-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol-final.pdf
October 15, 2024 - Moderate There is moderately confidence that that the true value of the estimate of interest is on
one … The true value of the
estimate may deviate slightly from the target of the certainty rating (i.e. may … Low There is low confidence that that the true value of the estimate of interest is on one side
of a … The true value of the estimate may
deviate from the target of the certainty rating (i.e. likely fall … Very Low There is very-low confidence that that the true value of the estimate of interest is on
one
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
November 01, 2013 - Further research is very unlikely to change
our confidence in the estimate of effect. … Further research may change our
confidence in the estimate of effect and may change the
estimate. … Further research is likely to change the
confidence in the estimate effect and is likely to change … the estimate … for
sensitivity of 95 percent (95% confidence interval [CI], 93
to 97%) and a pooled estimate for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-children_research-protocol.pdf
December 11, 2015 - For all analyses, we will use random-effects models
to estimate pooled or comparative effects. … Moderate We are moderately confident that the estimate of effect lies close to the true effect for
this … Low We have limited confidence that the estimate of effect lies close to the true effect for this
outcome … Insufficient We have no evidence, we are unable to estimate an effect, or we have no confidence in
the … estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
June 12, 2013 - Because the goal of any pooling is to estimate unconditional
effects,51 random-effects models will be … Further research is very
unlikely to change our confidence in the estimate of effect. … Further
research may change our confidence in the estimate of effect and may change the
estimate. … Further research is likely
the change the confidence in the estimate of effect and is likely to change … the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - factors, the overall evidence for each outcome was rated as
follows:16
• High—Very confident that estimate … • Moderate—Moderately confident that estimate of effect
lies close to true effect. … • Low—Limited confidence that estimate of effect lies
close to true effect; major or numerous deficiencies … Additional evidence necessary before
concluding that findings are stable or that estimate of
effect … • Insufficient—No evidence, unable to estimate an effect,
or no confidence in estimate of effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pelvic-pain_research-protocol.pdf
February 16, 2011 - evidence reflects the true effect and further research is very unlikely to change our confidence in
the estimate … confidence that the evidence reflects
the true effect and further research may change our confidence in the estimate … of effect and
may change the estimate), “low” (indicating low confidence that the evidence reflects … the true
effect and further research is likely to change our confidence in the estimate of effect and … is
likely to change the estimate), or “insufficient” (indicating that evidence is either unavailable
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
November 21, 2011 - evidence reflects the true effect and further research is
very unlikely to change our confidence in the estimate … that the evidence reflects the true effect and
further research may change our confidence in the estimate … of effect and may
change the estimate); “low” (indicating low confidence that the evidence
reflects … the true effect and further research is likely to change our confidence
in the estimate of effect … and is likely to change the estimate); or “insufficient”
(indicating that evidence is either unavailable
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-grading_methods.pdf
July 01, 2012 - Precision Precision is the degree of
certainty surrounding an effect
estimate with respect to a given … Score dichotomously as one of two levels of precision:
• Precise
• Imprecise
A precise estimate is … an estimate that would allow a
clinically useful conclusion. … An imprecise estimate is one
for which the confidence interval is wide enough to
include clinically … Publication bias indicates that
studies may have been published
selectively, with the result that the
estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - Further research is very
unlikely to change our confidence in the estimate of effect. … Further
research may change our confidence in the estimate of effect and may change the
estimate. … Further research is likely
to change the confidence in the estimate of effect and is likely to change … the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
March 29, 2011 - evidence reflects the true effect and further research is very unlikely to change our confidence in the
estimate … confidence that the evidence reflects the true
effect and further research may change our confidence in the estimate … of effect and may change the
estimate), “low” (indicating low confidence that the evidence reflects … the true effect and further
research is likely to change our confidence in the estimate of effect and … is likely to change the
estimate), or “insufficient” (indicating that evidence is either unavailable
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive.pdf
October 01, 2015 - The point estimate
of the risk ratio indicated a clinically unimportant
difference in the risk of CIN … was higher for statins than for high-dose
N-acetylcysteine despite having a lower pooled risk ratio
estimate … The pooled estimate of the risk ratio for statins plus
N-acetylcysteine versus N-acetylcysteine alone … The pooled estimate of the effect of ascorbic
acid compared with N-acetylcysteine demonstrated a
statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
July 01, 2012 - underlying disease processes to such
an extent that we are unable to develop a credible model to estimate … importantly, preexisting models will not have had the benefit of the current
systematic review to estimate … The systematic review could
synthesize available evidence, identify gaps, and estimate many necessary … Evidence exists to estimate the benefits and harms of pharmacologic therapy in those
with and without
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbi-protocol.pdf
August 09, 2021 - initial study design, we will assign SOE rating as high,
moderate, low, or ‘insufficient evidence’ to estimate … an effect.
10
High - We are very confident that the estimate of effect lies close to … Moderate - We are moderately confident that the estimate of effect lies close to the true
effect (the … Low - We have limited confidence that the estimate of effect lies close to the true effect (the
body … Insufficient - We are unable to estimate an effect or have no confidence in the estimate of
effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
November 29, 2023 - consistency
(similarity of effect direction and size); (4) precision (degree of certainty around an
estimate … An assessment of high indicates strong confidence that the estimate of effect
lies close to true effect … An assessment of insufficient indicates no
evidence was located, and we were unable to estimate an … effect or had no confidence in
the estimate of effect in the body of evidence, if one exists, and precludes
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
November 28, 2023 - consistency (similarity of effect
direction and size); 4) precision (degree of certainty around an estimate … An assessment of High indicates
strong confidence that the estimate of effect lies close to true effect … An
assessment of Insufficient indicates no evidence was located, and we were unable to
estimate an … effect or had no confidence in the estimate of effect; the body of evidence, if
one exists, precludes
-
effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
January 01, 2013 - Violations in assumptions that result in meaningful effect estimate changes provide insight into the … approach to see how different an “as-treated” analysis would be even if intention to treat is the main estimate … consider the use of more than one cohort definition or statistical approach to ensure that the effect estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
September 21, 2012 - For example, investigators may
not be able to estimate the power or precision
of their proposed comparisons … Describe:
- The primary outcome on which the study size
or power estimate is based.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
December 01, 2017 - cancer
dissemination following morcellation of fibroids, this
review also includes literature to estimate … across
all trials of medical management, UAE, or myomectomy
that included subsequent treatment to estimate … We fit a
11
Bayesian binomial random effects model to update the
estimate of prevalence of identifying … When we limit
the analysis to retrospective studies, the estimate is 0.09
percent (95% credible interval … Additionally, such studies will be better able
to estimate both common and rare harms, including the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - reflects the true effect and that
further research is very unlikely to change our confidence
in the estimate … of effect and will not change the estimate. … the
evidence reflects the true effect and that further research
may change our confidence in the estimate … of effect and
may change the estimate. … of effect and is likely to change the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
January 01, 2024 - feasible, we will also analyze multiple intake thresholds using
generalized least square models to estimate … will assign a consensus strength of evidence (SoE) rating of high, moderate, low, or
insufficient to estimate … This approach is consistent
with the concept that for imprecise evidence “any estimate of effect is