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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/predictors-trauma-care_research-protocol.pdf
    May 31, 2017 - • Moderate—We are moderately confident that the estimate of effect lies close to the true effect … • Low—We have limited confidence that the estimate of effect lies close to the true effect for this … that additional evidence is needed before concluding either that the findings are stable or that the estimate … • Insufficient—We have no evidence, we are unable to estimate an effect, or we have no confidence … in the estimate of effect for this outcome.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-adherence-interventions_research-protocol.pdf
    August 18, 2011 - to 50 percent are not taken as prescribed. 11 Across the many studies that have been conducted to estimate … Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of the effect and may change the estimate … Further research is likely to change our confidence in the estimate of the effect and is likely to change … the estimate.
  3. effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
    January 01, 2011 - epidemiologic terms (continued) Term Definition Comments Selection bias Distortion of treatment effect estimate … Information bias Distortion of treatment effect estimate as a result of measurement error in any variable … the estimation of the odds ratio in a case-control study is a computationally more efficient way to estimate … A conditional Poisson regression is used to estimate the incidence rate ratio within individuals. … Flexible matching strategies to increase power and efficiency to detect and estimate gene-environment
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
    June 01, 2012 - Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to change the confidence in the estimate of effect and is likely to change … the estimate … Of these 94 studies, 78 studies included sufficient data to estimate the sensitivity and specificity
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_executive.pdf
    March 01, 2017 - For the cognitive training interventions we did use Cohen’s D to estimate effect size where possible … consistency (similarity of effect direction and size); and (4) precision (degree of certainty around an estimate … • Moderate: Moderate confidence that the estimate reflects the true effect. … • Low: Limited confidence that the estimate of effect lies close to true effect. … Further research is likely to change confidence in the estimate of effect, and may change the estimate
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline_executive.pdf
    March 01, 2017 - For the cognitive training interventions we did use Cohen’s D to estimate effect size where possible … consistency (similarity of effect direction and size); and (4) precision (degree of certainty around an estimate … • Moderate: Moderate confidence that the estimate reflects the true effect. … • Low: Limited confidence that the estimate of effect lies close to true effect. … Further research is likely to change confidence in the estimate of effect, and may change the estimate
  7. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-medical-update_research-protocol.pdf
    February 16, 2016 - Moderate     Moderately  confident  that  the  estimate  of  effect  lies  close  to  the  true  effect … Low     Limited  confidence  that  the  estimate  of  effect  lies  close  to  the  true  effect  for … Additional  evidence  is   needed  before  concluding  that  the  findings  are  stable  or  that  the  estimate … Insufficient     No  evidence  or  unable  to  estimate  an  effect.   … No  confidence  in  the  estimate  of  effect  for  this   outcome.  
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
    December 05, 2018 - For all analyses, we will use random effects models to estimate pooled or comparative effects; unlike … Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of the effect and may change the estimate … Further research is likely to change our confidence in the estimate of the effect and is likely to change … the estimate.
  9. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
    October 01, 2011 - ; the directness of the evidence linking the intervention and health outcomes; the precision of the estimate … reflects the true effect and that further research is very unlikely to change our confidence in the estimate … of effect and may change the estimate; a “low” grade indicates low confidence that the evidence reflects … the true effect and further research is likely to change the confidence in the estimate of effect and … is likely to change the estimate; an “insufficient” grade indicates evidence either is unavailable or
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
    January 01, 2014 - For all analyses, we will use random-effects models to estimate pooled or comparative effects. … Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of the effect and may change the estimate … Further research is likely to change our confidence in the estimate of the effect and is likely to change … the estimate.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
    September 24, 2024 - Moderate We are moderately confident that the estimate of effect lies close to the true effect for this … Low We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
    October 27, 2017 - for the Management of Patients with Atrial Fibrillation recommends the use the CHADS2-VASc score to estimate … • Moderate—We are moderately confident that the estimate of effect lies close to the true effect … that additional evidence is needed before concluding either that the findings are stable or that the estimate … • Insufficient—We have no evidence, we are unable to estimate an effect, or we have no confidence … in the estimate of effect for this outcome.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
    July 01, 2012 - Typically patients are classified as diagnostic test positive or negative to estimate the test’s accuracy … development sample) by using the data to define cutoff levels or model its relationships to the outcome and estimate
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/people-with-disabilities-protocol.pdf
    January 16, 2024 - The four levels are: • High—Very confident that the estimate of effect lies close to the true effect … • Moderate—Confident that the estimate of effect lies close to the true effect for this outcome. … • Low—Limited confidence that the estimate of effect lies close to the true effect for this outcome … Additional evidence is needed before concluding either that the findings are stable or that the estimate … Investigators are unable to estimate an effect, or have no confidence in the estimate of effect for
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-postpartum-screening_research-protocol.pdf
    May 01, 2013 - We can, however, readily estimate the number of false-positive screening test results, or total referrals … Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to change the confidence in the estimate of effect and is likely to change … the estimate
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-metaanalysis_methods.pdf
    July 01, 2012 - prevailing reasoning, across studies sensitivity and specificity are likely negatively correlated: as one estimate … positive estimated correlation between sensitivity and specificity (e.g., based on the correlation estimate … It is also informative to estimate “summary” negative (or positive) predictive values for this test.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
    January 01, 2011 - specified depending on the area of research) 6±2 5±2 Is necessary information usually available to estimate … 5±2 4±2 Is subjective decision needed to estimate validity? 5±2 6±2 10 Table 2. … Systematic reviews should incorporate quality into the synthesis of evidence to estimate how it affects … sample Not reported Poor reporting The authors did not assess sampling bias Minor flaw Estimate … Reporting of prevalence Not clear Poor reporting Point prevalence Minor flaw Precision of estimate
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-users-amended-protocol.pdf
    June 21, 2019 - evaluating and weighing the combined results of the above domains: • High: Very confident that the estimate … • Moderate: Moderately confident that the estimate of effect lies close to the true effect for this … • Low: Limited confidence that the estimate of effect lies close to the true effect for this outcome … Additional evidence is needed before concluding either that the findings are stable or that the estimate … • Insufficient: No evidence, unable to estimate an effect, or have no confidence in the estimate
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol-final.pdf
    October 15, 2024 - Moderate There is moderately confidence that that the true value of the estimate of interest is on one … The true value of the estimate may deviate slightly from the target of the certainty rating (i.e. may … Low There is low confidence that that the true value of the estimate of interest is on one side of a … The true value of the estimate may deviate from the target of the certainty rating (i.e. likely fall … Very Low There is very-low confidence that that the true value of the estimate of interest is on one
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
    January 01, 2010 - meta-analyses,9-11,23-28 other more recent studies have demonstrated a DES survival advantage with a point-estimate … Utilizing propensity scores to estimate causal treatment effects with censored time- lagged data. … Model OR>1 indicates more DES; OR<1 indicates more BMS Odds Ratio Estimates Effect Point Estimate … Effective Health Care Research Report Number 17 29 Odds Ratio Estimates Effect Point Estimate … Effective Health Care Research Report Number 17 30 Odds Ratio Estimates Effect Point Estimate

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