-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
November 01, 2010 - K/DOQI CKD definition and stage classification, and utilizing a urinary
ACR >30 mg/g (adjusted to estimate … persistence) as the marker for kidney damage and
the Modification of Diet in Renal Disease (MDRD) formula to estimate … applying the more
accurate Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula to
estimate … patients for
worsening function or damage is only possible with laboratory testing (i.e., measures to
estimate … A new equation to estimate glomerular filtration rate.
Ann Intern Med. 2009;150(9):604-612.
4.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - These random effects will allow us to estimate the overall (population)
effect and the … Moderate We are moderately confident that the estimate of effect lies close to the true … Low We have limited confidence that the estimate of effect lies close to the true effect … Insufficient We have no evidence, we are unable to estimate an effect, or we have no … confidence in the
estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
November 30, 2014 - Very confident that the estimate of effect lies close to the true effect. … Moderately confident that the estimate of effect lies close to true effect. … Limited confidence that estimate of effect lies close to true effect; major or
numerous deficiencies … Additional evidence necessary before
concluding that findings are stable or that estimate of effect … No evidence, unable to estimate and effect, or no confidence in estimate of
effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_research-protocol.pdf
July 21, 2014 - For all analyses, we will use random-
effects models to estimate pooled or comparative effects. … We are moderately confident that the estimate of effect lies close to the true effect Moderate
for this … We have limited confidence that the estimate of effect lies close to the true effect Low
for this outcome … We have no evidence, we are unable to estimate an effect, or we have no confidence in Insufficient
the … estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children_research-protocol.pdf
November 01, 2010 - estimation results)
test used
summary measures
sample variability measures
precision of estimate … categories:
• High quality: Further research is very unlikely to change our confidence in
the estimate … Moderate quality: Further research is likely to have an important impact on
our confidence in the estimate … impact
on our confidence in the estimate of effect and is likely to change the estimate
• Insufficient … : Any estimate of effect is very uncertain
If concerns arise with the body of evidence, additional
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diagnostic-tests-accuracy_research.pdf
January 01, 2013 - The p ’s in
Table 4 estimate the corresponding probabilities (π ’s) in Table 3. … For example, the estimate
of the probability of a true positive result in study k is π̂ D
k , 1= x … We estimate TPR by T
PRk = π̂ D
k , 1 , and FPR by F
PRk = π̂ D
k , 1 . … For each combination of test results, the estimate of the population proportion
is
π̂ D
k = xDk … (41)
In an analogous manner, to estimate differences between summary logit-FPRs for tests i and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
January 01, 2014 - Further research may change our confidence in the estimate of the effect and may change the estimate. … the estimate. … Further research may change our confidence in the estimate of the effect and may change the estimate. … the estimate. … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
June 01, 2010 - This is still a much higher usage rate than
the estimate of 1.5% of rescue therapy in the “real world … The highest
estimate of off-label use that is consistent with any current data
(including the Premier … This high
estimate would assume that all patients receive an average dose of 90
mcg/kg body weight. … of
some 330,000 total eligible procedures.12 Even using the liberal
estimate provided in the Draft … A liberal estimate from the Premier dataset would suggest
that approximately 2,000 patients with ICH
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf
January 30, 2014 - In addition, we will use the full-text screening form to
estimate the numbers of studies available to … The random effects in such a model will allow both an estimate of the
overall (population) effect as … Moderate We are moderately confident that the estimate of effect lies close to the true effect
for this … Insufficient We have no evidence, we are unable to estimate an effect, or we have no
confidence in the … estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
January 01, 2013 - The estimation of the odds ratio in a case-control study is a computationally more efficient way to estimate … Flexible matching strategies to increase power and efficiency to detect and estimate gene-environment … A conditional Poisson regression is used to estimate the incidence rate ratio within individuals. … discuss the potential for confounding by time-varying factors and clearly state how the resulting effect estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
January 01, 2013 - Analyses of heterogeneity of treatment effect have two main goals:
To estimate treatment effects in clinically … To estimate treatment effects in clinically relevant subgroups (subgroup analysis)
2.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
November 01, 2012 - percent of patients after
at least 10 years of followup.14,30-35 Overall, studies of
community cohorts estimate … the true
8
effect and that further research is very unlikely to change
our confidence in the estimate … that the evidence
reflects the true effect and further research may change
our confidence in the estimate … of effect and may change
the estimate. … of effect
and is likely to change the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
February 01, 2018 - ► SMD is computed as the mean effect divided by a pooled estimate of the
standard error, putting … of the treatment and control groups:
𝑑𝑑 =
𝑚𝑚𝑁𝑁 −𝑚𝑚𝑚𝑚
𝑆𝑆𝑝𝑝𝑝𝑝𝑝𝑝𝑝𝑝𝑝𝑝𝑑𝑑
► This estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ankyloglossia_executive.pdf
May 01, 2015 - Further research may change our
confidence in the estimate of effect and may change the
estimate. … Further research is likely to change confidence
in the estimate of effect and is also likely to change … the
estimate … We considered the strength of
evidence (confidence in the estimate of effect) to be low
for an immediate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
July 18, 2011 - reflects the true effect and further research is very unlikely to change our confidence in the
estimate … the evidence reflects the
true effect and that further research may change our confidence in the estimate … of effect and may
change the estimate); “low” (indicating low confidence that the evidence reflects … the true effect
and that further research is likely to change our confidence in the estimate of effect … and is likely
to change the estimate); and (4) “insufficient” (indicating that evidence is either
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
February 23, 2012 - Further research is
very unlikely to change our confidence in the estimate of effect. … Further
research may change our confidence in the estimate of effect and may change the
estimate. … Further research is
likely to change the confidence in the estimate of effect and is likely to change … the
estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
November 03, 2011 - Further research is very unlikely to
change our confidence
in the estimate of effect. … Further research may change our
confidence in the estimate of effect and may change the
estimate. … Further research is likely to change the
confidence in the estimate of effect and is likely to change … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
June 06, 2011 - Further research
is very unlikely to change our confidence in the estimate of effect. … Further
research may change our confidence in the estimate of effect and may change
the estimate. … Further research
is likely to change the confidence in the estimate of effect and is likely to change … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy_research-protocol.pdf
September 14, 2016 - evidence reflects the true effect and further research is very
unlikely to change our confidence in the estimate … that the evidence reflects the true effect but further research could change
our confidence in the estimate … of the effect and may change the estimate); (3) “Low” grade
(indicating low confidence that the evidence … reflects the true effect and further research is likely
to change our confidence in the estimate of … the effect and is likely to change the estimate); and
(4) “Insufficient” grade (indicating evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
July 01, 2010 - Although it is possible to estimate diagnostic accuracy from a two-group trial, the
results of such … For the review, we will define a “precise” estimate of sensitivity or specificity as being
one for which … bound of the 95 percent confidence interval
(95% CI) is no more than 5 points away from the summary estimate … ; for example, a
sensitivity of 98 percent (95% CI: 97–100%) will be a precise estimate of sensitivity … ,
whereas a sensitivity of 98 percent (95% CI: 88–100%) will be an imprecise estimate of
sensitivity