-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
September 27, 2012 - estimation results)
Test used
Summary measures
Sample variability measures
Precision of estimate … Further research is very
unlikely to change our confidence in the estimate of effect. … Further
research may change our confidence in the estimate of effect and may change the
estimate. … Further research is likely
to change our confidence in the estimate of effect and is likely to change … the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetic-neuropathy_research-protocol.pdf
May 09, 2016 - Objectives for the Systematic Review
Background
Diabetic peripheral neuropathy
According to an estimate … that the evidence reflects
the true effect but further research could change our confidence in the estimate … of the effect and
may change the estimate);
(3) “low” strength of evidence (indicating low confidence … the evidence reflects the true
effect and further research is likely to change our confidence in the estimate … of the effect and is
likely to change the estimate); and
(4) “insufficient” strength of evidence (
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
March 31, 2010 - analyses by
omitting one study at a time to assess the influence of any single study on the pooled
estimate … that the evidence
reflects the true effect and further research may change our confidence in the estimate … of the effect and may change the estimate); (3) “low” grade (indicating low
confidence that the … evidence reflects the true effect and further research is likely to
change our confidence in the estimate … of the effect and is likely to change the
estimate); and (4) “insufficient” grade (evidence is unavailable
-
effectivehealthcare.ahrq.gov/sites/default/files/covariate-selection-chapter-7.pptx
January 01, 2013 - When the goal of comparative effectiveness research is to estimate the total causal effect of the treatment … mass index
Adjusting for a proxy or mismeasured confounder will reduce bias relative to the unadjusted estimate … Adjusting for a proxy or mismeasured confounder will reduce bias relative to the unadjusted estimate, … Another common problem in trying to estimate causal effects is that of unmeasured confounding. … predicted probability is then used as a balancing score or matching variable across treatment groups to estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
December 27, 2016 - another study
would not change the conclusions.
2) Moderate – We are moderately confident that the estimate … findings are likely to be stable, but some
doubt remains.
3) Low – We have limited confidence that the estimate … that additional evidence is
needed before concluding either that the findings are stable or that the
estimate … of effect is close to the true effect.
4) Insufficient – We have no evidence, we are unable to estimate … an effect, or
we have no confidence in the estimate of the effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - that the evidence reflects
the true effect, and further research may change our
confidence in the estimate … of effect and may change
the estimate); “low” (indicating low confidence that the
evidence reflects … the true effect, and further research is
likely to change our confidence in the estimate of effect … and is likely to change the estimate); or “insufficient”
(indicating that evidence is either unavailable … FS, and 89.1 percent for primary orchiopexy, slightly
lower in all types of surgery than the pooled estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
October 01, 2007 - Variable
Study of Neuroleptics
Can Between-Physician Differences in Prescribing Patterns Be
Used to Estimate … variable
(IV) methods that exploit differences in prescribing patterns be-
tween physicians may be used to estimate … In this article, we have evaluated the plausibility of the
conditions necessary for an estimate of a … “monotonicity,” is required to justify the use of conventional
IV estimators2 and in such cases the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
July 01, 2009 - The summary
estimate was derived from meta-analysis of three RCTs
that assessed the rhythm control of … The summary estimate was derived
from meta-analysis of six RCTs. … The evidence is
insufficient to estimate the predictive value of abnormal
EF or LAD on recurrence rates … The
evidence is insufficient to estimate the predictive value
of young or very old age.
4
5
There
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_appendixes.pdf
May 23, 2005 - First, it is not possible to obtain a highly stable
estimate when meta-regression is used to explain … 85.9%
(81.5% to 90.4%)
Summary
estimate
75.5%
(70.1% to 80.9%)
Summary
estimate
77.3%
( … 71.9% to 82.7%)
Summary
estimate
84.7%
(80.1% to 89.2%)
Heterogeneous,
no summary
estimate … 86.1%
(83.8% to
88.5%)
Summary
estimate
66.4%
(64.5% to
68.2%)
Summary
estimate
47.0% … (43.6% to
50.4%)
Summary
estimate
93.3%
(92.3% to
94.2%)
Heterogeneous,
no summary
estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
May 01, 2013 - The AHRQ evidence
review found a best estimate for period prevalence (the
proportion of the population … To estimate the balance of benefits and harms of different
screening strategies, we also adapted an … Despite sparse data for harms, we can readily
estimate the number of false-positive screening test results … Only one
study judged to be at high risk of bias provided a specific
estimate of the effect of a risk … This estimate could
be compared with the estimated number of unwanted
screening outcomes resulting
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-evidence-communication_research-protocol.pdf
July 31, 2012 - Precision—“the degree of certainty surrounding an effect estimate with respect to a given
outcome.” … interval, which indicates the reproducibility of the estimate. … Further research is very unlikely to
change our confidence in the estimate of effect. … Further research may change
our confidence in the estimate of the effect and may change the estimate … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infertility_research-protocol.pdf
October 12, 2015 - As recommended by the Guide, judgments about the benefit of performing a new quantitative
estimate will … , or provide a more up-to-date estimate reflecting current practice. … High—We are very confident that the estimate of effect lies close to the true effect
for this outcome … Insufficient—We have no evidence, we are unable to estimate an effect, or we have
no confidence in the … estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_executive.pdf
January 01, 2014 - Any subgroup
summary estimate based on fewer than three studies is
noted as such and should be interpreted … When the summary estimate and CI
were precise and crossed 1, we looked at the particular
studies to … effect estimates:
300 mg versus 600 mg clopidogrel loading dose
Outcome and Timing SOEa and Effect Estimate … versus fondaparinux (percutaneous coronary intervention cohort)
Outcome and Timing SOEa and Effect Estimate … single antiplatelet versus dual antiplatelet therapy (continued)
Outcome and Timing SOEa and Effect Estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/obesity-child_executive.pdf
March 31, 2010 - The results of each meta-analysis contributed to our
assessment of the precision of the estimate of … We
also assessed the precision of the estimate of the outcome
when we could not conduct meta-analysis … of the effect and may change the estimate;
(3) “low” grade, indicating low confidence that the
evidence … reflects the true effect, and further research is
likely to change our confidence in the estimate of … the effect
and is likely to change the estimate; and (4) “insufficient”
grade, indicating that evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment-update_research-protocol.pdf
December 31, 2017 - of 18.7 percent and a current PTSD
prevalence estimate of 9.1 percent7 among Vietnam veterans. … For all analyses, we will use
random-effects models to estimate pooled or comparative effects. … Further research is very unlikely
to change our confidence in the estimate of effect. … Further research may change
our confidence in the estimate of the effect and may change the estimate … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - combination
of systematic review and decision-analytic modeling
presented in this report allows us to estimate … injectable or implantable hormonal contraception)
Studies that do not include controls; i.e.,
an estimate … The second analysis was a direct comparison to
estimate the difference in outcomes between the average … Further
work—using quantitative methods to estimate the potential
benefit of primary prevention strategies … The likelihood that OC use decreases life expectancy is
low, but there is insufficient evidence to estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_research-protocol.pdf
December 23, 2014 - These random effects will allow both an estimate of the overall (population)
effect as well as an estimate … Moderate We are moderately confident that the estimate of effect lies close to the true effect for this … Low We have limited confidence that the estimate of effect lies close to the true effect for this
outcome … Insufficient We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-adherence_research-protocol.pdf
September 13, 2011 - Further
research is very unlikely to change our confidence in the estimate of
effect. … Further research may change our confidence in the estimate of
effect and may change the estimate. … Further
research is likely to change the confidence in the estimate of effect
and is likely to change … the estimate. … well-designed search, but will
provide a more useful answer to end-
users of the review than a quantitative
estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
January 27, 2012 - For quantitative syntheses, we will use random-effects models to estimate
pooled effects.42 For continuous … Further research is very
unlikely to change our confidence in the estimate of effect. … Further research may
change our confidence in the estimate of the effect and may change the estimate … Further research is likely to
change our confidence in the estimate of the effect and is likely to change … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
February 01, 2018 - Statistical models exist that assume consistency (consistency models) and
which allow for direct/indirect estimate … • Side-splitting: A node is a treatment and a side/edge is a
comparison.12
► Compares the pooled estimate … from direct evidence only to the pooled
estimate including both direct and indirect evidence.
12.