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  1. effectivehealthcare.ahrq.gov/products/c-difficile-update/research-protocol
    December 23, 2014 - consistency (similarity of effect direction and size); 4) precision (degree of certainty around an estimate … Moderate : Moderately confident that estimate of effect lies close to true effect. … Low : Limited confidence that estimate of effect lies close to true effect; major or numerous deficiencies … Additional evidence necessary before concluding that findings are stable or that estimate of effect is … Insufficient : No evidence, unable to estimate an effect, or no confidence in estimate of effect.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
    December 23, 2014 - consistency (similarity of effect direction and size); 4) precision (degree of certainty around an estimate … An imprecise estimate is one for which the confidence interval is wide enough to include clinically … • Moderate: Moderately confident that estimate of effect lies close to true effect. … Additional evidence necessary before concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence in estimate of effect
  3. effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
    February 01, 2008 - Further research is very unlikely to change our confidence in the estimate of effect. … of effect and may change the estimate. … the estimate. … Precision Precision refers to the degree of certainty surrounding an effect estimate with respect … A precise estimate is an estimate that would allow a clinically useful conclusion.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
    October 05, 2018 - An imprecise estimate is one for which the 15 confidence interval is wide enough to include … overall strength of evidence for each comparison and outcome as:[21] • High: Very confident that estimate … • Moderate: Moderately confident that estimate of effect lies close to true effect. … Additional evidence necessary before concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence in estimate of effect
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
    September 01, 2014 - studies (1980 or later) only if the evidence from systematic reviews was insufficient to support an estimate … We are very confident that the estimate of effect lies close to the true effect for this outcome. … We are moderately confident that the estimate of effect lies close to the true effect for this outcome … We have limited confidence that the estimate of effect lies close to the true effect for this outcome … We have no evidence, we are unable to estimate an effect, or we have no confidence in the estimate of
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
    February 01, 2008 - Further research is very unlikely to change our confidence in the estimate of effect. … of effect and may change the estimate. … the estimate. … Precision Precision refers to the degree of certainty surrounding an effect estimate with respect … A precise estimate is an estimate that would allow a clinically useful conclusion.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
    June 13, 2013 - Does a troponin elevation help to estimate prognosis after ACS in the following subgroups? a. … T, or hs troponin I) against another type of troponin assay, does a certain type of troponin test estimate … of the effect and may change the estimate); 3) “low” grade (indicating low confidence that the evidence … reflects the true effect and that further research is likely to change our confidence in the estimate … of the effect and is likely to change the estimate); and 4) “insufficient” grade (evidence is unavailable
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pwd-care-interventions-protocol.pdf
    February 22, 2019 - An imprecise estimate is one for which the confidence interval is wide enough to include clinically … the overall strength of evidence for each outcome will be rated as: • High: Very confident that estimate … • Moderate: Moderately confident that estimate of effect lies close to true effect. … Additional evidence necessary before concluding that findings are stable or that estimate of effect is … • Insufficient: No evidence, unable to estimate an effect, or no confidence in estimate of effect.
  9. effectivehealthcare.ahrq.gov/products/quality-tools-testing/research
    March 20, 2012 - The ratios were combined to give an overall estimate of differences in effect estimates with inverse-variance
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
    January 10, 2012 - Precision refers to the degree of certainty surrounding the effect estimate with respect to a given … A precise estimate is an estimate that would allow a clinically useful conclusion. … Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change confidence in the estimate of effect and may change the estimate. … the estimate.
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diagnostic-tests-accuracy_research.pdf
    January 01, 2013 - The p ’s in Table 4 estimate the corresponding probabilities (π ’s) in Table 3. … For example, the estimate of the probability of a true positive result in study k is π̂ Dk , 1= x … We estimate TPR by T PRk = π̂ Dk , 1 , and FPR by F PRk = π̂ Dk , 1 . … For each combination of test results, the estimate of the population proportion is π̂ Dk = x D k … (41) In an analogous manner, to estimate differences between summary logit-FPRs for tests i and
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
    September 20, 2017 - , the consistency of results from new studies compared to the pooled estimate, and the likelihood that … • Precision: describes the level of certainty of the estimate of effect for a particular outcome … • Moderate—We are moderately confident that the estimate of effect lies close to the true effect … • Insufficient—We have no evidence, we are unable to estimate an effect, or we have no confidence … in the estimate of effect for this outcome.
  13. effectivehealthcare.ahrq.gov/products/treatments-acute-pain/protocol
    January 02, 2020 - Moderate—We are moderately confident that the estimate of effect lies close to the true effect for this … Low—We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient—We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
    November 27, 2012 - one of many references Hepatitis C virus infection in USA: an estimate of true prevalence Eric Chak … , and actually fairly close to the Chak study estimate (1.6% vs. 2.0%). … Changed to revised estimate 0.86 (0.78 - 0.95). … This had no effect on the estimate. … Hepatitis C virus infection in USA: an estimate of true prevalence.
  15. effectivehealthcare.ahrq.gov/products/undescended-testicle/research-protocol
    September 02, 2011 - evidence reflects the true effect and further research is very unlikely to change our confidence in the estimate … confidence that the evidence reflects the true effect and further research may change our confidence in the estimate … of effect and may change the estimate); “low” (indicating low confidence that the evidence reflects … the true effect and further research is likely to change our confidence in the estimate of effect and … is likely to change the estimate); or “insufficient” (indicating that evidence is either unavailable
  16. effectivehealthcare.ahrq.gov/products/bladder-cancer-non-muscle-invasive/research-protocol
    July 21, 2014 - Moderate — We are moderately confident that the estimate of effect lies close to the true effect for … Low — We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient — We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
    April 25, 2013 - size across the body of evidence is reasonably large (e.g., 4000 patients), EPCs can consider the estimate … Precision is based on the confidence interval of the estimate; the estimate can be precise, even if … and 95% confidence intervals) in Amgen’s reanalysis, the point estimate for on-study mortality was … However, when the BEST study was excluded, the point estimate for on-study mortality decreased from … A meta-analysis of these 8 trials resulted in an estimate of 1.92 (95% CI 0.97, 2.86; I2 0%).delarue
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
    May 01, 2013 - The AHRQ evidence review found a best estimate for period prevalence (the proportion of the population … To estimate the balance of benefits and harms of different screening strategies, we also adapted an … Despite sparse data for harms, we can readily estimate the number of false-positive screening test results … Only one study judged to be at high risk of bias provided a specific estimate of the effect of a risk … This estimate could be compared with the estimated number of unwanted screening outcomes resulting
  19. effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
    January 01, 2013 - Analyses of heterogeneity of treatment effect have two main goals: To estimate treatment effects in clinically … To estimate treatment effects in clinically relevant subgroups (subgroup analysis) 2.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
    November 01, 2017 - of Patients Study Design/ ROB Consistency/ Directness Precision/ Publication Bias Effect Estimate … of Patients Study Design/ ROB Consistency/ Directness Precision/ Publication Bias Effect Estimate … Number of Patients Study Design/ROB Consistency/ Directness Precision Publication Bias Effect Estimate

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