-
effectivehealthcare.ahrq.gov/products/c-difficile-update/research-protocol
December 23, 2014 - consistency (similarity of effect direction and size); 4) precision (degree of certainty around an estimate … Moderate : Moderately confident that estimate of effect lies close to true effect. … Low : Limited confidence that estimate of effect lies close to true effect; major or numerous deficiencies … Additional evidence necessary before concluding that findings are stable or that estimate of effect is … Insufficient : No evidence, unable to estimate an effect, or no confidence in estimate of effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - consistency (similarity of effect direction and size); 4) precision (degree of certainty
around an estimate … An imprecise estimate is one for which the confidence interval is wide enough to
include clinically … • Moderate: Moderately confident that estimate of effect lies close to true effect. … Additional evidence necessary
before concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence in
estimate of effect
-
effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
February 01, 2008 - Further research is very unlikely to change our confidence in the
estimate of effect. … of effect and may
change the estimate. … the estimate. … Precision
Precision refers to the degree of certainty surrounding an effect estimate with
respect … A precise estimate is
an estimate that would allow a clinically useful conclusion.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/research-protocol-osteoporosis_2.pdf
October 05, 2018 - An imprecise estimate is one for which the
15
confidence interval is wide enough to include … overall strength of evidence for each
comparison and outcome as:[21]
• High: Very confident that estimate … • Moderate: Moderately confident that estimate of effect lies close to true effect. … Additional evidence necessary before
concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence in estimate
of effect
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
September 01, 2014 - studies (1980 or later) only if the evidence from
systematic reviews was insufficient to support an
estimate … We are very confident that the estimate of effect
lies close to the true effect for this outcome. … We are moderately confident that the
estimate of effect lies close to the true effect for this
outcome … We have limited confidence that the estimate of
effect lies close to the true effect for this outcome … We have no evidence, we are unable to
estimate an effect, or we have no confidence in the
estimate of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
February 01, 2008 - Further research is very unlikely to change our confidence in the
estimate of effect. … of effect and may
change the estimate. … the estimate. … Precision
Precision refers to the degree of certainty surrounding an effect estimate with
respect … A precise estimate is
an estimate that would allow a clinically useful conclusion.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
June 13, 2013 - Does a troponin elevation help to estimate prognosis after ACS in the following
subgroups?
a. … T, or hs troponin I) against another type of troponin assay, does a certain
type of troponin test estimate … of the effect
and may change the estimate); 3) “low” grade (indicating low confidence that the
evidence … reflects the true effect and that further research is likely to change our
confidence in the estimate … of the effect and is likely to change the estimate); and 4)
“insufficient” grade (evidence is unavailable
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pwd-care-interventions-protocol.pdf
February 22, 2019 - An imprecise estimate is one for which the confidence interval is wide enough to
include clinically … the overall strength of evidence for each outcome will be
rated as:
• High: Very confident that estimate … • Moderate: Moderately confident that estimate of effect lies close to true effect. … Additional evidence necessary before
concluding that findings are stable or that estimate of effect is … • Insufficient: No evidence, unable to estimate an effect, or no confidence in
estimate of effect.
-
effectivehealthcare.ahrq.gov/products/quality-tools-testing/research
March 20, 2012 - The ratios were combined to give an overall estimate of differences in effect estimates with inverse-variance
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
January 10, 2012 - Precision
refers to the degree of certainty surrounding the effect estimate with respect to a given … A precise estimate is an estimate that would allow a clinically useful
conclusion. … Further research is very unlikely to change our confidence in the
estimate of effect. … Further research may change confidence in the estimate of effect
and may change the estimate. … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diagnostic-tests-accuracy_research.pdf
January 01, 2013 - The p ’s in
Table 4 estimate the corresponding probabilities (π ’s) in Table 3. … For example, the estimate
of the probability of a true positive result in study k is π̂ Dk , 1= x … We estimate TPR by T
PRk = π̂ Dk , 1 , and FPR by F
PRk = π̂ Dk , 1 . … For each combination of test results, the estimate of the population proportion
is
π̂ Dk = x
D
k … (41)
In an analogous manner, to estimate differences between summary logit-FPRs for tests i and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
September 20, 2017 - , the consistency of results from new studies compared to the
pooled estimate, and the likelihood that … • Precision: describes the level of certainty of the estimate of effect for a
particular outcome … • Moderate—We are moderately confident that the estimate of effect lies
close to the true effect … • Insufficient—We have no evidence, we are unable to estimate an effect, or
we have no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/products/treatments-acute-pain/protocol
January 02, 2020 - Moderate—We are moderately confident that the estimate of effect lies close to the true effect for this … Low—We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient—We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_disposition-comments.pdf
November 27, 2012 - one of many references
Hepatitis C virus infection in USA: an estimate of true
prevalence Eric Chak … , and actually fairly close to the Chak
study estimate (1.6% vs. 2.0%). … Changed to revised estimate 0.86 (0.78 - 0.95). … This had no effect
on the estimate. … Hepatitis C virus infection in USA: an estimate of true prevalence.
-
effectivehealthcare.ahrq.gov/products/undescended-testicle/research-protocol
September 02, 2011 - evidence reflects the true effect and further research is very unlikely to change our confidence in the estimate … confidence that the evidence reflects the true effect and further research may change our confidence in the estimate … of effect and may change the estimate); “low” (indicating low confidence that the evidence reflects … the true effect and further research is likely to change our confidence in the estimate of effect and … is likely to change the estimate); or “insufficient” (indicating that evidence is either unavailable
-
effectivehealthcare.ahrq.gov/products/bladder-cancer-non-muscle-invasive/research-protocol
July 21, 2014 - Moderate — We are moderately confident that the estimate of effect lies close to the true effect for … Low — We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient — We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
April 25, 2013 - size across
the body of evidence is reasonably large (e.g.,
4000 patients), EPCs can consider the estimate … Precision is based on the confidence interval of
the estimate; the estimate can be precise, even if … and 95% confidence intervals) in Amgen’s reanalysis, the point
estimate for on-study mortality was … However, when the BEST study was excluded, the
point estimate for on-study mortality decreased from … A
meta-analysis of these 8 trials resulted in an
estimate of 1.92 (95% CI 0.97, 2.86; I2
0%).delarue
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
May 01, 2013 - The AHRQ evidence
review found a best estimate for period prevalence (the
proportion of the population … To estimate the balance of benefits and harms of different
screening strategies, we also adapted an … Despite sparse data for harms, we can readily
estimate the number of false-positive screening test results … Only one
study judged to be at high risk of bias provided a specific
estimate of the effect of a risk … This estimate could
be compared with the estimated number of unwanted
screening outcomes resulting
-
effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
January 01, 2013 - Analyses of heterogeneity of treatment effect have two main goals:
To estimate treatment effects in clinically … To estimate treatment effects in clinically relevant subgroups (subgroup analysis)
2.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
November 01, 2017 - of
Patients
Study
Design/
ROB
Consistency/
Directness
Precision/
Publication
Bias
Effect
Estimate … of
Patients
Study
Design/
ROB
Consistency/
Directness
Precision/
Publication
Bias
Effect
Estimate … Number of
Patients
Study
Design/ROB
Consistency/
Directness
Precision
Publication
Bias
Effect Estimate