-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_executive.pdf
February 01, 2014 - or when the reported effect estimate appeared to
contradict the reported events per person-time. … reflects the true effect and further research is
likely to change our confidence in the estimate of … the
effect and is likely to change the estimate
• “Insufficient” grade: evidence is unavailable; … HSTCL (insufficient data to
estimate incidence)
Insufficient We identified 37 unique cases of HSTCL … All cancers (insufficient data
to estimate incidence)
Low The risk of other cancers did not differ
-
effectivehealthcare.ahrq.gov/products/bladder-cancer-muscle-invasive/research-protocol
July 21, 2014 - precise estimates on outcomes for which studies are similar enough to provide a meaningful combined estimate … Moderate — We are moderately confident that the estimate of effect lies close to the true effect for … Low — We have limited confidence that the estimate of effect lies close to the true effect for this outcome … Insufficient — We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
July 19, 2023 - • Precision: Describes the level of certainty of the estimate of effect for a particular
outcome, … where a precise estimate is one that allows a clinically useful
conclusion. … • Moderate: We are moderately confident that the estimate of effect lies close to the
true effect … • Insufficient: We have no evidence, we are unable to estimate an effect, or we have
no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - • Moderate—We are moderately confident that the estimate of effect lies close to the true
effect … • Low—We have limited confidence that the estimate of effect lies close to the true effect
for this … that additional evidence is needed before concluding either that the findings are
stable or that the estimate … • Insufficient—We have no evidence, we are unable to estimate an effect, or we have no
confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/products/worker-health/research-protocol
May 26, 2015 - of evidence
Grade
Definition
Source: Berkman et al. 23
High
We are very confident that the estimate … Moderate
We are moderately confident that the estimate of effect lies close to the true effect for … Low
We have limited confidence that the estimate of effect lies close to the true effect for this outcome … Insufficient
We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/products/antipsychotics/research-protocol
September 06, 2018 - when there is higher heterogeneity. 24 For dichotomous outcomes, we will calculate a pooled effect estimate … that the evidence reflects the true effect but further research could change our confidence in the estimate … of the effect and may change the estimate); (3) "low" grade (indicating low confidence that the evidence … reflects the true effect and further research is likely to change our confidence in the estimate of … the effect and is likely to change the estimate); and (4) "insufficient" grade (indicating evidence is
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - OR=0.66; 95% Bayesian
credible interval [BCI]: 0.53, 0.82) and neonatal mortality
(meta-estimate OR … Among
the trials in the meta-estimate, the risk of preterm birth
was 46.6 percent among women in the … The aggregate estimate
suggests progestogen treatment in women with preterm
labor decreases the risk … of preterm birth before 37 weeks
(meta-estimate OR=0.26; 95% BCI: 0.10, 0.49). … Among the trials in the meta-estimate,
the risk of preterm birth was 47.5 percent among women
in the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostatic-hyperplasia-medications_research-protocol.pdf
April 21, 2015 - similarity of effect direction and size among studies); (4) precision (degree
of certainty around an estimate … An imprecise estimate is one for which the
confidence interval is wide enough to include clinically … • Moderate: Moderately confident that estimate of effect lies close to true
effect. … Additional evidence
necessary before concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence
in estimate of effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
February 01, 2016 - 2 RCTs Insufficient Unable to estimate 2 RCTs Insufficient
Antiseizure medications No evidence -- -- … NSAID Unable to estimate 1 RCT Insufficient Unable to estimate 1 RCT Insufficient
NSAID vs. … NSAID Unable to estimate 1 RCT Insufficient Unable to estimate 1 RCT Insufficient
NSAID vs. … NSAID Unable to estimate 1 RCT Insufficient Unable to estimate 1 RCT Insufficient
NSAID vs. … Unable to estimate 1 SR (13 RCTs) Insufficient Unable to estimate 1 SR (13 RCTs) Insufficient
Kinesio
-
effectivehealthcare.ahrq.gov/products/carioverter-difibrillators/abstract
April 14, 2010 - Aim 4: To estimate the incidence of various potential short and long-term adverse events following ICD
-
effectivehealthcare.ahrq.gov/products/cervical-ripening/protocol
January 16, 2020 - Precision (precise or imprecise)
Degree of certainty surrounding an effect estimate as it relates to … Moderate—we are moderately confident that the estimate of effect lies close to the true effect for this … Low—we have limited confidence that the estimate of effect lies close to the true effect for this outcome … Insufficient—we have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/products/noninvasive-nonpharm-pain-update/protocol
March 01, 2019 - Precision: describes the level of certainty of the estimate of effect for a particular outcome with … a precise estimate being on that allows a clinically useful conclusion; graded as precise or imprecise … Moderate— We are moderately confident that the estimate of effect lies close to the true effect for this … Insufficient— We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
June 01, 2023 - • Precision: Describes the level of certainty of the estimate of effect for a particular
outcome, … where a precise estimate is one that allows a clinically useful
conclusion. … • Moderate: We are moderately confident that the estimate of effect lies close to the
true effect … • Insufficient: We have no evidence, we are unable to estimate an effect, or we have
no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
December 11, 2018 - • Precision: describes the level of certainty of the estimate of effect for a
particular outcome … • Moderate—We are moderately confident that the estimate of effect lies
close to the true effect … • Low—We have limited confidence that the estimate of effect lies close to
the true effect for this … • Insufficient—We have no evidence, we are unable to estimate an effect, or
we have no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
May 01, 2013 - Further research is unlikely
to change our confidence in the estimate of the effect. … Further research may change our confidence in the estimate of the effect and may change the estimate. … the estimate. … Further research may change our confidence in the estimate of the effect and may change the estimate. … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preoperative-testing_disposition-comments.pdf
January 29, 2014 - We also reran with the profile likelihood random-effects model
(pl), which had a negative estimate for … Also the point estimate RR = 0.5 indicates a difference larger
than 20% (the typical definition of MID … The MID system does, in
fact, rely on the 95% CIs, not the point estimate. … (the magnitude of the point estimate should be
taken into account in some way). … As noted, this was done only to provide a rough estimate to
compare adverse event rates.
-
effectivehealthcare.ahrq.gov/products/psoriasis-chronic/research-protocol
September 27, 2011 - A precise estimate is an estimate that would allow a clinically useful conclusion. … Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change confidence in the estimate of effect and may change the estimate. … Further research is likely to change confidence in the estimate of effect and is likely to change the … estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - Prevalence studies estimate about 1 to 4%
of the population has bipolar disorder, with relatively similar … An imprecise estimate is one for
which the confidence interval is wide enough to include clinically … • Moderate: Moderately confidence that estimate of effect lies close to true
effect. … Additional evidence necessary
before concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence in
estimate of effect
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - Further research is
very unlikely to change our confidence in the estimate of effect. … Further research may
change our confidence in the estimate of effect and may change the estimate. … the estimate. … Any estimate of effect is
very uncertain. … A precise estimate is an estimate that would
allow a clinically useful conclusion.
-
effectivehealthcare.ahrq.gov/products/kidney-stone-prevention/research-protocol
June 15, 2011 - link between intervention and outcome); and 4) precision (degree of certainty surrounding an effect estimate … A precise estimate is one that would yield a clinically meaningful conclusion. … of effect and may change the estimate. … that the evidence reflects the true effect; further research is likely to change confidence in the estimate … of effect and is likely to change the estimate.