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effectivehealthcare.ahrq.gov/products/plant-based-chronic-pain-treatment/protocol
November 03, 2020 - Moderate— We are moderately confident that the estimate of effect lies close to the true effect for this … Low— We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient— We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
February 01, 2019 - least three studies reporting outcomes that are
homogeneous enough to provide a meaningful combined estimate … • Moderate—We are moderately confident that the estimate of effect lies close to the true
effect for … • Low—We have limited confidence that the estimate of effect lies close to the true effect
for this … • Insufficient—We have no evidence, we are unable to estimate an effect, or we have no
confidence in … the estimate of effect for this outcome.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
January 28, 2019 - pertaining to each KQ will be classified into four categories:
1) High – We are very confident that the estimate … another study would not change the conclusions.
2) Moderate – We are moderately confident that the estimate … that additional evidence is needed before concluding either that the
findings are stable or that the estimate … of effect is close to the true effect.
4) Insufficient – We have no evidence, we are unable to estimate … an effect, or we have
no confidence in the estimate of the effect for this outcome.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
October 01, 2022 - procedures
may cause seizure freedom in some infants; however, the precise proportion is too
variable to estimate … cause seizure freedom in some infants (SOE: Low);
however, the precise proportion is too variable to estimate
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/mmm-draft-protocol-amendment.pdf
February 02, 2022 - consistency (similarity of
effect direction and size); 4) precision (degree of certainty around an estimate … An imprecise estimate is one for which the confidence interval is
wide enough to include clinically … ● Moderate: Moderately confident that estimate of effect lies close to true effect. … Additional evidence necessary before concluding that
findings are stable or that estimate of effect … ● Insufficient: No evidence, unable to estimate an effect, or no confidence in estimate of
effect
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
July 01, 2012 - The worse the
deviation of the reference test from the unobserved “truth,” the poorer the estimate of … More accurately, a study of diagnostic
accuracy tries to estimate quantities that are functions of the … The data in the 2 X 2 table are then sufficient to estimate the four remaining probabilities
(α1, β1 … Because the four probabilities necessarily sum to 1, it is sufficient to estimate
any three. … Note that the naïve estimate for the sensitivity and specificity of the index
test approach the true
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
November 13, 2014 - consistency
(similarity of effect direction and size); (4) precision (degree of certainty around an
estimate … An imprecise estimate is one for which the confidence interval is wide enough to
include clinically … the overall strength of evidence for each outcome will be
rated as:41
• High: Very confident that estimate … Additional evidence
necessary before concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence
in estimate of effect
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/telehealth-acute-chronic_research-protocol.pdf
February 15, 2017 - • Moderate—Confident that the estimate of effect lies close to the true effect for this
outcome. … • Low—Limited confidence that the estimate of effect lies close to the true effect for this
outcome … Investigators are unable to estimate an effect, or have no
confidence in the estimate of effect for … In this project DM will be used to estimate the
clinical and cost outcomes of telehealth consultations … for a selected clinical condition and to
estimate the impact of different payment models for telehealth
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effectivehealthcare.ahrq.gov/products/chronic-pain-opioid-treatment/research-protocol
December 19, 2013 - Moderate — We are moderately confident that the estimate of effect lies close to the true effect for … Low — We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient — We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/products/osteoarthritis-pain/research-protocol
August 05, 2010 - ; the directness of the evidence linking the intervention and health outcomes; the precision of the estimate … reflects the true effect and that further research is very unlikely to change our confidence in the estimate … of effect and may change the estimate; (3) “low” grade indicates low confidence that the evidence reflects … the true effect and further research is likely to change the confidence in the estimate of effect and … is likely to change the estimate; (4) “insufficient” grade indicates evidence either is unavailable
-
effectivehealthcare.ahrq.gov/products/multiple-sclerosis/research-protocol
December 17, 2013 - these factors, the overall evidence for each outcome will be rated as: 16
High : Very confident that estimate … Moderate : Moderately confident that estimate of effect lies close to true effect. … Low : Limited confidence that estimate of effect lies close to true effect; major or numerous deficiencies … Additional evidence necessary before concluding that findings are stable or that estimate of effect is … Insufficient : No evidence, unable to estimate and effect, or no confidence in estimate of effect.
-
effectivehealthcare.ahrq.gov/products/weight-loss-surgery/research-protocol
December 14, 2010 - For trials that are judged sufficiently clinically similar to warrant meta-analysis, we will estimate … Further research is very unlikely to change our confidence on the estimate of effect. … Further research may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to change our confidence in the estimate of effect and is likely to change … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
December 17, 2013 - consistency (similarity of effect direction and size); and (4) precision (degree of
certainty around an estimate … • Moderate: Moderately confident that estimate of effect lies close to true effect. … • Low: Limited confidence that estimate of effect lies close to true effect; major or
numerous deficiencies … Additional evidence necessary before
concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate and effect, or no confidence in
estimate of effect
-
effectivehealthcare.ahrq.gov/products/integrated-pain-management/protocol
November 10, 2020 - of effect for a particular outcome with a precise estimate being on that allows a clinically useful … Moderate
We are moderately confident that the estimate of effect lies close to the true effect for … Low
We have limited confidence that the estimate of effect lies close to the true effect for this … Insufficient
We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/products/bipolar-disorder-treatment/research-protocol
June 23, 2014 - Prevalence studies estimate about 1 to 4% of the population has bipolar disorder, with relatively similar … Moderate : Moderately confidence that estimate of effect lies close to true effect. … Low : Limited confidence that estimate of effect lies close to true effect; major or numerous deficiencies … Additional evidence necessary before concluding that findings are stable or that estimate of effect is … Insufficient : No evidence, unable to estimate an effect, or no confidence in estimate of effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
November 29, 2016 - Opioid overdoses
have serious adverse health consequences, even when not fatal; although difficult to
estimate … • Moderate—We are moderately confident that the estimate of effect lies close
to the true effect … • Low—We have limited confidence that the estimate of effect lies close to the
true effect for this … • Insufficient—We have no evidence, we are unable to estimate an effect, or we
have no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
September 18, 2012 - For groups
of events that appear in at least three trials, a meta-analysis can estimate the odds ratio … Further research is very
unlikely to change our confidence in the estimate of effect. … Further research
may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to
change our confidence in the estimate of effect and is likely to change … the estimate.
-
effectivehealthcare.ahrq.gov/products/diagnostic-errors-emergency/protocol
December 21, 2020 - evidence reflects the true effect and further research is very unlikely to change our confidence in the estimate … that the evidence reflects the true effect but further research could change our confidence in the estimate … of the effect and may change the estimate); (3) "low" grade (indicating low confidence that the evidence … reflects the true effect and further research is likely to change our confidence in the estimate of … the effect and is likely to change the estimate); and (4) "insufficient" grade (indicating evidence is
-
effectivehealthcare.ahrq.gov/products/migraine-treatments/protocol
January 08, 2020 - initial study design, we will assign SOE rating as high, moderate, low, or 'insufficient evidence to estimate … High— We are very confident that the estimate of effect lies close to the true effect (the body of evidence … Moderate— We are moderately confident that the estimate of effect lies close to the true effect (the … Low— We have limited confidence that the estimate of effect lies close to the true effect (the body of … Insufficient— We have no evidence, are unable to estimate an effect, or have no confidence in the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
January 09, 2020 - initial study design, we will assign SOE rating as high,
moderate, low, or ‘insufficient evidence to estimate … High - We are very confident that the estimate of effect lies close to the true effect (the body
of … deficiencies and is judged to be stable).
11
Moderate - We are moderately confident that the estimate … Low - We have limited confidence that the estimate of effect lies close to the true effect (the
body … Insufficient - We have no evidence, are unable to estimate an effect, or have no confidence in
the estimate