-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - Further research is
very unlikely to change our confidence in the estimate of effect. … Further research may
change our confidence in the estimate of effect and may change the estimate. … the estimate. … Any estimate of effect is
very uncertain. … A precise estimate is an estimate that would
allow a clinically useful conclusion.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - Prevalence studies estimate about 1 to 4%
of the population has bipolar disorder, with relatively similar … An imprecise estimate is one for
which the confidence interval is wide enough to include clinically … • Moderate: Moderately confidence that estimate of effect lies close to true
effect. … Additional evidence necessary
before concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence in
estimate of effect
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
February 01, 2019 - least three studies reporting outcomes that are
homogeneous enough to provide a meaningful combined estimate … • Moderate—We are moderately confident that the estimate of effect lies close to the true
effect for … • Low—We have limited confidence that the estimate of effect lies close to the true effect
for this … • Insufficient—We have no evidence, we are unable to estimate an effect, or we have no
confidence in … the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
January 28, 2019 - pertaining to each KQ will be classified into four categories:
1) High – We are very confident that the estimate … another study would not change the conclusions.
2) Moderate – We are moderately confident that the estimate … that additional evidence is needed before concluding either that the
findings are stable or that the estimate … of effect is close to the true effect.
4) Insufficient – We have no evidence, we are unable to estimate … an effect, or we have
no confidence in the estimate of the effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - August 05, 2010
evidence linking the intervention and health outcomes; the precision of the estimate … of effect and may change the estimate; (3) “low” grade
indicates low confidence that the evidence reflects … the true effect and further research is
likely to change the confidence in the estimate of effect and … is likely to change the
estimate; (4) “insufficient” grade indicates evidence either is unavailable … weaken the overall body of evidence for that particular outcome or make it difficult
to accurately estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
December 19, 2013 - and weighing
the combined results of the above domains:
• High — We are very confident that the estimate … • Moderate — We are moderately confident that the estimate of effect lies
close to the true effect … • Low — We have limited confidence that the estimate of effect lies close to
the true effect for this … • Insufficient — We have no evidence, we are unable to estimate an effect,
or we have no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
December 18, 2019 - • Precision (precise or imprecise)
o Degree of certainty surrounding an effect estimate as it relates … • Moderate—we are moderately confident that the estimate of effect lies close to the true
effect … • Low—we have limited confidence that the estimate of effect lies close to the true effect
for this … • Insufficient—we have no evidence, we are unable to estimate an effect, or we have no
confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/s5.pdf
October 01, 2007 - outcome, may be the better approach in
using such simulations.16
IV methods also allow investigators to estimate … A simulation-based evaluation of
methods to estimate the impact of an adverse event on hospital length … variable study of neuroleptics: can between-physician dif-
ferences in prescribing patterns be used to estimate … Using propensity scores
subclassification to estimate effects of longitudinal treatments: an ex-
ample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
May 19, 2011 - precision (precise or imprecise) of the evidence based on the degree of
certainty surrounding an effect estimate … A precise estimate is an estimate that would allow a
conclusion to be drawn. … An imprecise estimate is one for which the confidence interval is wide
enough to include clinically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_appendixes.pdf
October 06, 2006 - (From text or tables, not survival curves)
οSurvival-Overall οMortality-Overall οKaplan Meier Estimate … Outcome 1: _________________ ο Kaplan Meier Estimate ο Raw Percentage ο Absolute Numbers οOther … PCI
CABG
PCI/CABG ratio
Outcome 2: _________________ ο Kaplan Meier Estimate … 11
Appendix E: Abstraction Forms (continued)
Outcome 3: _________________ ο Kaplan Meier Estimate … PCI
CABG
PCI/CABG ratio
Outcome 4: _________________ ο Kaplan Meier Estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_clinician.pdf
September 01, 2014 - For many other interventions,
the evidence is insufficient to permit an estimate of their
benefits … Regarding Possible Harms
Other than for risperidone and aripiprazole, there was not
enough evidence to estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
April 01, 2013 - the peak velocity of
the tricuspid regurgitant (TR) jet is measured by Doppler
and—along with an estimate … TRV/TG/sPAP compared
with RHC
SOE = Moderate
(19 studies, 2,459 patients)
Echocardiographic estimate … TRV/VTIRVOT compared
with RHC
SOE = Moderate
(6 studies, 196 patients)
Echocardiographic estimate … First, echocardiography in a small but significant number
of patients may not produce an estimate of … Second, echocardiographic estimates of
sPAP often over- or under-estimate pulmonary artery
pressure
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research.pdf
June 01, 2017 - ................................................................................................ 2
Estimate … A secondary goal was to estimate the person-hours required to complete these analyses. … Estimate of Person-Hours Required to Complete the Project
EPC staff routinely log the time spent working … We used the staff
logs and co-investigator reports to estimate the total staff time and co-investigator … Background and Objectives
Methods
Scope and General Approach
Searching CT.gov
Matching Studies
Estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-protocol.pdf
April 08, 2024 - • Precision (precise or imprecise)
o Describes the level of certainty of the effect estimate for … a particular outcome with a
precise estimate being one that allows a clinically useful conclusion. … Low Limited confidence that the estimate of effect lies close to the true effect
for this outcome. … Additional evidence is needed before concluding
either that the findings are stable or that the estimate … Insufficient Investigators are unable to estimate an effect or have no confidence in the
estimate of
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
January 12, 2022 - for a particular
outcome with a precise estimate being one that allows a clinically useful
conclusion … strength of evidence grades
Strength of
Evidence
Description
High We are very confident that the estimate … Moderate We are moderately confident that the estimate of effect lies close
to the true effect for this … Low We have limited confidence that the estimate of effect lies close to
the true effect for this outcome … an effect, or we have no confidence in
the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation_research-protocol.pdf
October 25, 2010 - By one estimate, 2 percent of the U.S. population lives with TBI-related
disabilities.
9
Source … evidence reflects the true effect; further research is very
unlikely to change the confidence in the estimate … of effect and may change the estimate.
3. … the evidence reflects the true effect; further research is likely
to change the confidence in the estimate … of effect and is likely to change the estimate.
4.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults_research-protocol.pdf
December 20, 2011 - direct link between intervention and outcome)
Precision (degree of certainty surrounding an effect estimate … evidence reflects the true effect; further
research is very unlikely to change the confidence in the estimate … of effect and may
change the estimate.
3. … the evidence reflects the true effect; further
research is likely to change the confidence in the estimate … of effect and is
likely to change the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - when there is higher heterogeneity.24 For
dichotomous outcomes, we will calculate a pooled effect estimate … that the evidence reflects the true
effect but further research could change our confidence in the estimate … of the effect
and may change the estimate); (3) “low” grade (indicating low confidence that the
evidence … reflects the true effect and further research is likely to change our
confidence in the estimate of … the effect and is likely to change the estimate); and (4)
“insufficient” grade (indicating evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
April 21, 2011 - effectiveness, confounding by indication makes it unlikely that these studies
would yield a valid estimate … Further research is very
unlikely to change our confidence in the estimate of effect. … Further research
may change our confidence in the estimate of effect and may change the estimate. … Further research is likely
to change the confidence in the estimate of effect and is likely to change … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
May 26, 2015 - the grades of overall strength of evidence
Grade Definition
High We are very confident that the estimate … Moderate We are moderately confident that the estimate of effect lies close to the true effect
for … Low We have limited confidence that the estimate of effect lies close to the true effect for
this outcome … Insufficient We have no evidence, we are unable to estimate an effect, or we have no confidence
in … the estimate of effect for this outcome.