-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
November 13, 2014 - consistency
(similarity of effect direction and size); (4) precision (degree of certainty around an
estimate … An imprecise estimate is one for which the confidence interval is wide enough to
include clinically … the overall strength of evidence for each outcome will be
rated as:41
• High: Very confident that estimate … Additional evidence
necessary before concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence
in estimate of effect
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-draft-protocol.pdf
March 14, 2024 - and the initial study design, we will assign SOE rating as high,
moderate, low, or insufficient to estimate … High: We are very confident that the estimate of effect lies close to the true effect (the body
of evidence … Moderate: We are moderately confident that the estimate of effect lies close to the true effect
(the … Low: We have limited confidence that the estimate of effect lies close to the true effect (the
body … Insufficient: We are unable to estimate an effect or have no confidence in the estimate of
effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
December 17, 2013 - consistency (similarity of effect direction and size); and (4) precision (degree of
certainty around an estimate … • Moderate: Moderately confident that estimate of effect lies close to true effect. … • Low: Limited confidence that estimate of effect lies close to true effect; major or
numerous deficiencies … Additional evidence necessary before
concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate and effect, or no confidence in
estimate of effect
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-protocol-amended.pdf
November 18, 2024 - (e.g., National
Health and Nutrition Examination Survey), use this database to estimate usual nutrient … • Precision (precise or imprecise)
o This describes the level of certainty of the effect estimate … for a particular outcome with
a precise estimate being one that allows a clinically useful conclusion … Low Limited confidence that the estimate of effect lies close to the true effect for
this outcome. … Insufficient Investigators are unable to estimate an effect or have no confidence in the
estimate of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-executive-summary.pdf
November 01, 2024 - When more than two
studies were available, different designs and/or methods to calculate the estimate … Studies without a protein or amino acid requirement estimate (k=6) reported
outcomes such as growth,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
January 09, 2020 - initial study design, we will assign SOE rating as high,
moderate, low, or ‘insufficient evidence to estimate … High - We are very confident that the estimate of effect lies close to the true effect (the body
of … deficiencies and is judged to be stable).
11
Moderate - We are moderately confident that the estimate … Low - We have limited confidence that the estimate of effect lies close to the true effect (the
body … Insufficient - We have no evidence, are unable to estimate an effect, or have no confidence in
the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
September 18, 2012 - For groups
of events that appear in at least three trials, a meta-analysis can estimate the odds ratio … Further research is very
unlikely to change our confidence in the estimate of effect. … Further research
may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to
change our confidence in the estimate of effect and is likely to change … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
November 29, 2016 - Opioid overdoses
have serious adverse health consequences, even when not fatal; although difficult to
estimate … • Moderate—We are moderately confident that the estimate of effect lies close
to the true effect … • Low—We have limited confidence that the estimate of effect lies close to the
true effect for this … • Insufficient—We have no evidence, we are unable to estimate an effect, or we
have no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - • Moderate—We are moderately confident that the estimate of effect lies close to the true
effect … • Low—We have limited confidence that the estimate of effect lies close to the true effect
for this … that additional evidence is needed before concluding either that the findings are
stable or that the estimate … • Insufficient—We have no evidence, we are unable to estimate an effect, or we have no
confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol.pdf
February 01, 2023 - sign)
• Precision (precise or imprecise): Describes the degree of certainty surrounding an effect
estimate … given outcome, based on the width of confidence intervals
relative to a clinically important effect estimate … Moderate We are moderately confident that the estimate of effect lies close to the true
effect for this … Low We have limited confidence that the estimate of effect lies close to the true
effect for this outcome … Insufficient We are unable to estimate an effect, or we have no confidence in the estimate
of effect
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
July 19, 2023 - • Precision: Describes the level of certainty of the estimate of effect for a particular
outcome, … where a precise estimate is one that allows a clinically useful
conclusion. … • Moderate: We are moderately confident that the estimate of effect lies close to the
true effect … • Insufficient: We have no evidence, we are unable to estimate an effect, or we have
no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_executive.pdf
February 01, 2014 - or when the reported effect estimate appeared to
contradict the reported events per person-time. … reflects the true effect and further research is
likely to change our confidence in the estimate of … the
effect and is likely to change the estimate
• “Insufficient” grade: evidence is unavailable; … HSTCL (insufficient data to
estimate incidence)
Insufficient We identified 37 unique cases of HSTCL … All cancers (insufficient data
to estimate incidence)
Low The risk of other cancers did not differ
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
June 01, 2023 - • Precision: Describes the level of certainty of the estimate of effect for a particular
outcome, … where a precise estimate is one that allows a clinically useful
conclusion. … • Moderate: We are moderately confident that the estimate of effect lies close to the
true effect … • Insufficient: We have no evidence, we are unable to estimate an effect, or we have
no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
February 01, 2016 - 2 RCTs Insufficient Unable to estimate 2 RCTs Insufficient
Antiseizure medications No evidence -- -- … NSAID Unable to estimate 1 RCT Insufficient Unable to estimate 1 RCT Insufficient
NSAID vs. … NSAID Unable to estimate 1 RCT Insufficient Unable to estimate 1 RCT Insufficient
NSAID vs. … NSAID Unable to estimate 1 RCT Insufficient Unable to estimate 1 RCT Insufficient
NSAID vs. … Unable to estimate 1 SR (13 RCTs) Insufficient Unable to estimate 1 SR (13 RCTs) Insufficient
Kinesio
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/child-growth-development-outcomes-protocol.pdf
August 19, 2024 - (e.g., National Health and Nutrition
Examination Survey), use this database to estimate usual nutrient … • Precision (precise or imprecise)
o This describes the level of certainty of the effect estimate … for a particular outcome
with a precise estimate being one that allows a clinically useful conclusion … Low Limited confidence that the estimate of effect lies close to the true effect
for this outcome. … Insufficient Investigators are unable to estimate an effect or have no confidence in
the estimate of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostatic-hyperplasia-medications_research-protocol.pdf
April 21, 2015 - similarity of effect direction and size among studies); (4) precision (degree
of certainty around an estimate … An imprecise estimate is one for which the
confidence interval is wide enough to include clinically … • Moderate: Moderately confident that estimate of effect lies close to true
effect. … Additional evidence
necessary before concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence
in estimate of effect.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - OR=0.66; 95% Bayesian
credible interval [BCI]: 0.53, 0.82) and neonatal mortality
(meta-estimate OR … Among
the trials in the meta-estimate, the risk of preterm birth
was 46.6 percent among women in the … The aggregate estimate
suggests progestogen treatment in women with preterm
labor decreases the risk … of preterm birth before 37 weeks
(meta-estimate OR=0.26; 95% BCI: 0.10, 0.49). … Among the trials in the meta-estimate,
the risk of preterm birth was 47.5 percent among women
in the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
May 01, 2013 - Further research is unlikely
to change our confidence in the estimate of the effect. … Further research may change our confidence in the estimate of the effect and may change the estimate. … the estimate. … Further research may change our confidence in the estimate of the effect and may change the estimate. … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol-amendment.pdf
February 03, 2025 - sign)
• Precision (precise or imprecise): Describes the degree of certainty surrounding an effect
estimate … given outcome, based on the width of confidence intervals
relative to a clinically important effect estimate … Moderate We are moderately confident that the estimate of effect lies close to the true
effect for this … Low We have limited confidence that the estimate of effect lies close to the true
effect for this outcome … Insufficient We are unable to estimate an effect, or we have no confidence in the estimate
of effect
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
February 05, 2025 - and the initial study design, we will assign SOE rating as high,
moderate, low, or insufficient to estimate … High: We are very confident that the estimate of effect lies close to the true effect (the body
of evidence … Moderate: We are moderately confident that the estimate of effect lies close to the true effect
(the … Low: We have limited confidence that the estimate of effect lies close to the true effect (the
body … Insufficient: We are unable to estimate an effect or have no confidence in the estimate of
effect.