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effectivehealthcare-admin.ahrq.gov/products/health-information-exchange/research-protocol
December 01, 2019 - Moderate: We are moderately confident that the estimate of effect lies close to the true effect for this … Low: We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient: We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.
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effectivehealthcare-admin.ahrq.gov/products/crohns-disease/research-protocol
December 01, 2019 - We will estimate treatment effects relative to the reference treatment (basic parameters, i.e. comparisons … evidence reflects the true effect and further research is very unlikely to change our confidence in the estimate … of the effect and may change the estimate); (3) “low” grade (indicating low confidence that the evidence … reflects the true effect and further research is likely to change our confidence in the estimate of … the effect and is likely to change the estimate); and (4) “insufficient” grade (evidence is unavailable
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effectivehealthcare-admin.ahrq.gov/products/cultural-competence/research-protocol
December 01, 2019 - An imprecise estimate is one for which the confidence interval is wide enough to include clinically distinct … Moderate : Moderately confidence that estimate of effect lies close to true effect. … Low : Limited confidence that estimate of effect lies close to true effect; major or numerous deficiencies … Additional evidence necessary before concluding that findings are stable or that estimate of effect is … Insufficient : No evidence, unable to estimate an effect, or no confidence in estimate of effect.
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effectivehealthcare-admin.ahrq.gov/products/head-neck-cancer-update/research-protocol
December 01, 2019 - Precision
Required
Precision is the degree of certainty surrounding an effect estimate with respect … Score as one of two levels:
Precise
Imprecise
A precise estimate is one that would allow … Moderate
We are moderately confident that the estimate of effect lies close to the true effect for … Insufficient
We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/obesity-research-methods_research-protocol.pdf
February 08, 2017 - features, approaches to linking
data sources, or analytic methods) would help to strengthen efforts to estimate … of
intervention
Group composition changing over time;
Comparison group not providing
accurate estimate … just below the cutoff are assumed to be very similar, so comparing these groups allows
for a valid estimate … KQ4: What are the important gaps related to the methods used to estimate the effect of
programs, policies … KQ5: What are the important gaps related to risks of bias in population-level data
sources used to estimate
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
January 15, 2015 - • Precision: describes the level of certainty of the estimate of effect for a
particular outcome … • Moderate—We are moderately confident that the estimate of effect lies
close to the true effect … • Insufficient—We have no evidence, we are unable to estimate an effect, or
we have no confidence … in the estimate of effect for this outcome. … Computed tomography (CT) with fractional flow reserve (FFR)
In order to estimate coronary blood flow
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
February 01, 2018 - studies with zero events in one arm, or studies with sparse binary data
but no zero events, obtain an estimate
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effectivehealthcare-admin.ahrq.gov/products/dietary-protein-intake/research
November 01, 2024 - When more than two studies were available, different designs and/or methods to calculate the estimate
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
July 28, 2016 - As recommended by the Methods Guide, judgments
about the benefit of performing a new quantitative estimate … , or provide a more up-to-date estimate reflecting current practice. … • Moderate—We are moderately confident that the estimate of effect lies close to
the true effect … • Low—We have limited confidence that the estimate of effect lies close to the true
effect for this … Published online: July 28, 2016 20
have no confidence in the estimate of effect for this outcome
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
January 01, 2012 - of effect and may
change the estimate; (3) low, indicating low confidence that
further research is … very likely to have an important impact
on the confidence in the estimate of effect and is likely … to change the estimate; and (4) insufficient, indicating
that evidence either is unavailable or does … - Estimate the proportion of individuals with
abnormal one-time abnormalities who meet the
criteria … A new equation to
estimate glomerular filtration rate. Ann Intern Med 2009 May
5;150(9):604-12.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/s131.pdf
October 01, 2007 - The final estimate is similar to that
obtained as a pooled estimate of 3 pravastatin RCTs in patients … Propensity scores estimate each patient’s proba-
bility of treatment given all measured covariates. … an estimate for the age group comparable to
ours for this study. … Nonetheless, even if the gold standard estimate for our cohort
5 population had been the PROSPER trial … In the end, however, it
may not be possible to determine whether the changes in the
effect estimate seen
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effectivehealthcare-admin.ahrq.gov/products/grant-manuscripts/borrowing-strength-abstract
June 01, 2024 - strength (BoS) statistic, which quantifies the percentage reduction in the uncertainty of the effect estimate
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effectivehealthcare-admin.ahrq.gov/products/lung-cancer-nonsurgical-therapies/research-protocol
December 01, 2019 - Because the goal of any pooling is to estimate unconditional effects, 39 random-effects models will … Further research is very unlikely to change our confidence in the estimate of effect.
Moderate. … Further research may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to change our confidence in the estimate of effect and is likely to change … the estimate.
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effectivehealthcare-admin.ahrq.gov/products/care-adults-down-syndrome/protocol
February 01, 2025 - Moderate: Moderately confident that estimate of effect lies close to true effect. … Low: Limited confidence that estimate of effect lies close to true effect; major or numerous deficiencies … Additional evidence necessary before concluding that findings are stable or that estimate of effect is … Insufficient: No evidence, unable to estimate an effect, or no confidence in estimate of effect. … Current Estimate of Down Syndrome Population Prevalence in the United States.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/care-adults-down-syndrome-protocol-amendment.pdf
February 05, 2025 - evidence for each intervention/comparison/
outcome will be rated as:
● High: Very confident that estimate … ● Moderate: Moderately confident that estimate of effect lies close to true effect. … Additional evidence necessary before
concluding that findings are stable or that estimate of effect … ● Insufficient: No evidence, unable to estimate an effect, or no confidence in estimate
of effect … Current Estimate of Down Syndrome
Population Prevalence in the United States.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
November 01, 2010 - K/DOQI CKD definition and stage classification, and utilizing a urinary
ACR >30 mg/g (adjusted to estimate … persistence) as the marker for kidney damage and
the Modification of Diet in Renal Disease (MDRD) formula to estimate … applying the more
accurate Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula to
estimate … patients for
worsening function or damage is only possible with laboratory testing (i.e., measures to
estimate … A new equation to estimate glomerular filtration rate.
Ann Intern Med. 2009;150(9):604-612.
4.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/strategies-integrating-behavioral-health-protocol.pdf
August 04, 2022 - The four levels are:
• High—Very confident that the estimate of effect lies close to the true effect … • Moderate—Confident that the estimate of effect lies close to the true effect for this
outcome. … • Low—Limited confidence that the estimate of effect lies close to the true effect for this
outcome … Additional
evidence is needed before concluding either that the findings are stable or that the
estimate … Investigators are unable to estimate an effect or have no
confidence in the estimate of effect for this
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
April 03, 2014 - Very confident that the estimate of effect lies close to the true effect. … Moderately confident that the estimate of effect lies close to true effect. … Limited confidence that estimate of effect lies close to true effect; major or
numerous deficiencies … Additional evidence necessary before
concluding that findings are stable or that estimate of effect … No evidence, unable to estimate and effect, or no confidence in estimate of
effect.
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effectivehealthcare-admin.ahrq.gov/products/radiation-therapy-bone-metastases/protocol
August 01, 2022 - for a particular outcome with a precise estimate being one that allows a clinically useful conclusion … Strength of Evidence
Description
High
We are very confident that the estimate … Moderate
We are moderately confident that the estimate of effect lies close to the true effect … Low
We have limited confidence that the estimate of effect lies close to the true effect for this … Insufficient
We are unable to estimate an effect, or we have no confidence in the estimate of effect
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effectivehealthcare-admin.ahrq.gov/products/ptsd-adult-treatment/research-protocol
December 01, 2020 - of 18.7 percent and a current PTSD prevalence estimate of 9.1 percent 4 among Vietnam veterans. … For all analyses, we will use random-effects models to estimate pooled or comparative effects. … Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of the effect and may change the estimate. … the estimate.