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effectivehealthcare-admin.ahrq.gov/products/depression-harms/research-protocol
May 01, 2019 - (2) Moderate—We are moderately confident that the estimate of effect lies close to the true effect … (3) Low—We have limited confidence that the estimate of effect lies close to the true effect for this … that additional evidence is needed before concluding either that the findings are stable or that the estimate … (4) Insufficient—We have no evidence, we are unable to estimate an effect, or we have no confidence … in the estimate of the effect for this outcome.
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effectivehealthcare-admin.ahrq.gov/products/asthma-provider-adherence/research-protocol
December 01, 2019 - with the DerSimonian and Laird formula for continuous outcomes. 36 We will calculate a pooled effect estimate … evidence reflects the true effect, and further research is very unlikely to change our confidence in the estimate … of the effect and may change the estimate); 3) “low” grade (indicating low confidence that the evidence … reflects the true effect, and further research is likely to change our confidence in the estimate of … the effect and is likely to change the estimate); and 4) “insufficient” grade (evidence is unavailable
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effectivehealthcare-admin.ahrq.gov/products/nppv-respiratory-failure/research-protocol
December 01, 2020 - addressing effectiveness, confounding by indication makes it unlikely that these studies would yield a valid estimate … Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to change the confidence in the estimate of effect and is likely to change … the estimate.
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effectivehealthcare-admin.ahrq.gov/products/arthritis-knee-physical-therapy/research-protocol
December 01, 2019 - We will include observational studies when trial data are insufficient to estimate the benefits and harms … Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to change the confidence in the estimate of effect and is likely to change … the estimate.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-infertility_research.pdf
June 01, 2017 - ................................................................................................ 2
Estimate … A secondary goal was to estimate the person-hours required to complete these analyses. … Estimate of Person-Hours Required to Complete the Project
EPC staff routinely log the time spent working … We used the staff
logs and co-investigator reports to estimate the total staff time and co-investigator … Background and Objectives
Methods
Scope and General Approach
Searching CT.gov
Matching Studies
Estimate
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
December 18, 2019 - • Precision (precise or imprecise)
o Degree of certainty surrounding an effect estimate as it relates … • Moderate—we are moderately confident that the estimate of effect lies close to the true
effect … • Low—we have limited confidence that the estimate of effect lies close to the true effect
for this … • Insufficient—we have no evidence, we are unable to estimate an effect, or we have no
confidence … in the estimate of effect for this outcome.
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effectivehealthcare-admin.ahrq.gov/products/management-infantile-epilepsy/research
March 01, 2023 - procedures may cause seizure freedom in some infants; however, the precise proportion is too variable to estimate … seizure freedom in some infants (SOE: low for both), but the precise proportion is too variable to estimate … of the effect and is likely to change the estimate. … of the effect and may change the estimate. … evidence reflects the true effect; further research is very unlikely to change our confidence in the estimate
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effectivehealthcare-admin.ahrq.gov/products/cervical-ripening/protocol
May 01, 2020 - Precision (precise or imprecise)
Degree of certainty surrounding an effect estimate as it relates … Moderate—we are moderately confident that the estimate of effect lies close to the true effect for this … Low—we have limited confidence that the estimate of effect lies close to the true effect for this outcome … Insufficient—we have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.
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effectivehealthcare-admin.ahrq.gov/products/coronary-artery-disease-testing/research-protocol
December 01, 2019 - Precision: describes the level of certainty of the estimate of effect for a particular outcome with a … precise estimate being on that allows a clinically useful conclusion; graded as precise or imprecise … High—We are very confident that the estimate of effect lies close to the true effect for this outcome … estimate of effect for this outcome. … Computed tomography (CT) with fractional flow reserve (FFR)
In order to estimate coronary blood flow
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effectivehealthcare-admin.ahrq.gov/products/obesity-research-methods/research-protocol
January 01, 2019 - features, approaches to linking data sources, or analytic methods) would help to strengthen efforts to estimate … just below the cutoff are assumed to be very similar, so comparing these groups allows for a valid estimate … questions:
KQ1: What are the important gaps in existing population-based data sources used to estimate … KQ4: What are the important gaps related to the methods used to estimate the effect of programs, policies … KQ5: What are the important gaps related to risks of bias in population-level data sources used to estimate
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/long-term-care-adults_research-protocol.pdf
December 20, 2011 - direct link between intervention and outcome)
Precision (degree of certainty surrounding an effect estimate … evidence reflects the true effect; further
research is very unlikely to change the confidence in the estimate … of effect and may
change the estimate.
3. … the evidence reflects the true effect; further
research is likely to change the confidence in the estimate … of effect and is
likely to change the estimate.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/asthma-provider-adherence_research-protocol.pdf
March 02, 2012 - with the DerSimonian
and Laird formula for continuous outcomes.36 We will calculate a pooled effect estimate … that the evidence reflects the true effect, and further research may
change our confidence in the estimate … of the effect and may change the estimate); 3) “low” grade
(indicating low confidence that the evidence … reflects the true effect, and further research is likely to
change our confidence in the estimate of … the effect and is likely to change the estimate); and 4)
“insufficient” grade (evidence is unavailable
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation_research-protocol.pdf
October 25, 2010 - By one estimate, 2 percent of the U.S. population lives with TBI-related
disabilities.
9
Source … evidence reflects the true effect; further research is very
unlikely to change the confidence in the estimate … of effect and may change the estimate.
3. … the evidence reflects the true effect; further research is likely
to change the confidence in the estimate … of effect and is likely to change the estimate.
4.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - when there is higher heterogeneity.24 For
dichotomous outcomes, we will calculate a pooled effect estimate … that the evidence reflects the true
effect but further research could change our confidence in the estimate … of the effect
and may change the estimate); (3) “low” grade (indicating low confidence that the
evidence … reflects the true effect and further research is likely to change our
confidence in the estimate of … the effect and is likely to change the estimate); and (4)
“insufficient” grade (indicating evidence
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/nppv-respiratory-failure_research-protocol.pdf
April 21, 2011 - effectiveness, confounding by indication makes it unlikely that these studies
would yield a valid estimate … Further research is very
unlikely to change our confidence in the estimate of effect. … Further research
may change our confidence in the estimate of effect and may change the estimate. … Further research is likely
to change the confidence in the estimate of effect and is likely to change … the estimate.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
May 26, 2015 - the grades of overall strength of evidence
Grade Definition
High We are very confident that the estimate … Moderate We are moderately confident that the estimate of effect lies close to the true effect
for … Low We have limited confidence that the estimate of effect lies close to the true effect for
this outcome … Insufficient We have no evidence, we are unable to estimate an effect, or we have no confidence
in … the estimate of effect for this outcome.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-protocol.pdf
April 08, 2024 - • Precision (precise or imprecise)
o Describes the level of certainty of the effect estimate for … a particular outcome with a
precise estimate being one that allows a clinically useful conclusion. … Low Limited confidence that the estimate of effect lies close to the true effect
for this outcome. … Additional evidence is needed before concluding
either that the findings are stable or that the estimate … Insufficient Investigators are unable to estimate an effect or have no confidence in the
estimate of
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effectivehealthcare-admin.ahrq.gov/products/carbohydrate-intake/protocol
May 01, 2024 - outcome with a precise estimate being one that allows a clinically useful conclusion. … Moderate
Moderately confident that the estimate of effect lies close to the true effect for this … Low
Limited confidence that the estimate of effect lies close to the true effect for this outcome … Additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient
Investigators are unable to estimate an effect or have no confidence in the estimate
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effectivehealthcare-admin.ahrq.gov/products/quantitative-synthesis-expanded-methods/methods
December 01, 2019 - This bias is caused by measurement error in the control rate estimate and correlation between the control … placebo-controlled studies of Alzheimer’s drugs using standardized mean different and the combined estimate … The estimate of rate takes into account both the number of new cases, and followup time of population … Specify the scale to estimate the quality of the study and how internal and external validity of the … If study results are not quantitatively combined, a forest plot without a summary estimate can still
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
February 01, 2014 - To estimate the risk of death we relied on 2007
estimates from the U.S. … To
estimate the incidence rate we assumed a 50 percent increase from age category 65-74 years based … Gail/NCI index to estimate the relative weighted number of harm minus benefit outcomes
Gail/NCI benefit … However, little research
has been done so far to estimate the impact of joint distributions of outcomes … The USPSTF proposed to use risk prediction equations
to estimate the absolute 10-year risks of MI.