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effectivehealthcare-admin.ahrq.gov/products/genitourinary-syndrome/research
March 01, 2025 - different from the estimate of effect. … Low: Our confidence in the effect estimate is limited; the true effect may be substantially different … from the estimate of the effect. … Moderate: We are moderately confident in the effect estimate; the true effect is likely to be close … to the effect estimate, but there is a possibility that it is substantially different.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
September 18, 2012 - For groups
of events that appear in at least three trials, a meta-analysis can estimate the odds ratio … Further research is very
unlikely to change our confidence in the estimate of effect. … Further research
may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to
change our confidence in the estimate of effect and is likely to change … the estimate.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
November 29, 2016 - Opioid overdoses
have serious adverse health consequences, even when not fatal; although difficult to
estimate … • Moderate—We are moderately confident that the estimate of effect lies close
to the true effect … • Low—We have limited confidence that the estimate of effect lies close to the
true effect for this … • Insufficient—We have no evidence, we are unable to estimate an effect, or we
have no confidence … in the estimate of effect for this outcome.
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effectivehealthcare-admin.ahrq.gov/products/long-term-care-adults/research-protocol
December 01, 2019 - direct link between intervention and outcome)
Precision (degree of certainty surrounding an effect estimate … evidence reflects the true effect; further research is very unlikely to change the confidence in the estimate … of effect and may change the estimate. … that the evidence reflects the true effect; further research is likely to change the confidence in the estimate … of effect and is likely to change the estimate.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
January 09, 2020 - initial study design, we will assign SOE rating as high,
moderate, low, or ‘insufficient evidence to estimate … High - We are very confident that the estimate of effect lies close to the true effect (the body
of … deficiencies and is judged to be stable).
11
Moderate - We are moderately confident that the estimate … Low - We have limited confidence that the estimate of effect lies close to the true effect (the
body … Insufficient - We have no evidence, are unable to estimate an effect, or have no confidence in
the estimate
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effectivehealthcare-admin.ahrq.gov/products/migraine-treatments/protocol
March 01, 2020 - initial study design, we will assign SOE rating as high, moderate, low, or 'insufficient evidence to estimate … High— We are very confident that the estimate of effect lies close to the true effect (the body of evidence … Moderate— We are moderately confident that the estimate of effect lies close to the true effect (the … Low— We have limited confidence that the estimate of effect lies close to the true effect (the body of … Insufficient— We have no evidence, are unable to estimate an effect, or have no confidence in the estimate
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effectivehealthcare-admin.ahrq.gov/products/worker-health/research-protocol
December 01, 2019 - Moderate
We are moderately confident that the estimate of effect lies close to the true effect for … Low
We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient
We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
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effectivehealthcare-admin.ahrq.gov/products/antidepressants-seniors-pneumonia/research
January 01, 2020 - We then examined each potential confounding factor individually using a change-in-estimate criterion … ten percent or more, we considered it to be a confounding factor and retained it in the "change-in-estimate … The change-in-estimate adjusted ORs for cyclic agents and SSRI/SSNRIs were also similar to the corresponding … of the large number of cases of hospitalization for depression, and the narrow CIs for this effect estimate …
Characteristic
Cases N (%)
Controls N (%)
Minimally adjusted OR (95% CI) *
Change-in-estimate
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effectivehealthcare-admin.ahrq.gov/products/antipsychotics/research-protocol
January 01, 2019 - when there is higher heterogeneity. 24 For dichotomous outcomes, we will calculate a pooled effect estimate … that the evidence reflects the true effect but further research could change our confidence in the estimate … of the effect and may change the estimate); (3) "low" grade (indicating low confidence that the evidence … reflects the true effect and further research is likely to change our confidence in the estimate of … the effect and is likely to change the estimate); and (4) "insufficient" grade (indicating evidence is
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/child-growth-development-outcomes-protocol-amended.pdf
November 18, 2024 - (e.g., National
Health and Nutrition Examination Survey), use this database to estimate usual nutrient … • Precision (precise or imprecise)
o This describes the level of certainty of the effect estimate … for a particular outcome with
a precise estimate being one that allows a clinically useful conclusion … Low Limited confidence that the estimate of effect lies close to the true effect for
this outcome. … Insufficient Investigators are unable to estimate an effect or have no confidence in the
estimate of
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effectivehealthcare-admin.ahrq.gov/products/child-growth-development-outcomes/protocol
November 01, 2024 - (e.g., National Health and Nutrition Examination Survey), use this database to estimate usual nutrient … outcome with a precise estimate being one that allows a clinically useful conclusion. … Moderate Moderately confident that the estimate of effect lies close to the true effect for this outcome … Low Limited confidence that the estimate of effect lies close to the true effect for this outcome. … Insufficient Investigators are unable to estimate an effect or have no confidence in the estimate of
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/crohns-disease_executive.pdf
February 01, 2014 - or when the reported effect estimate appeared to
contradict the reported events per person-time. … reflects the true effect and further research is
likely to change our confidence in the estimate of … the
effect and is likely to change the estimate
• “Insufficient” grade: evidence is unavailable; … HSTCL (insufficient data to
estimate incidence)
Insufficient We identified 37 unique cases of HSTCL … All cancers (insufficient data
to estimate incidence)
Low The risk of other cancers did not differ
-
effectivehealthcare-admin.ahrq.gov/products/bereaved-persons/protocol
December 01, 2023 - Precision: Describes the level of certainty of the estimate of effect for a particular outcome, where … a precise estimate is one that allows a clinically useful conclusion. … Moderate: We are moderately confident that the estimate of effect lies close to the true effect for … Insufficient: We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
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effectivehealthcare-admin.ahrq.gov/products/tethered-spinal-cord/protocol
August 01, 2023 - Precision: Describes the level of certainty of the estimate of effect for a particular outcome, where … a precise estimate is one that allows a clinically useful conclusion. … Moderate: We are moderately confident that the estimate of effect lies close to the true effect for … Insufficient: We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
July 19, 2023 - • Precision: Describes the level of certainty of the estimate of effect for a particular
outcome, … where a precise estimate is one that allows a clinically useful
conclusion. … • Moderate: We are moderately confident that the estimate of effect lies close to the
true effect … • Insufficient: We have no evidence, we are unable to estimate an effect, or we have
no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - • Moderate—We are moderately confident that the estimate of effect lies close to the true
effect … • Low—We have limited confidence that the estimate of effect lies close to the true effect
for this … that additional evidence is needed before concluding either that the findings are
stable or that the estimate … • Insufficient—We have no evidence, we are unable to estimate an effect, or we have no
confidence … in the estimate of effect for this outcome.
-
effectivehealthcare-admin.ahrq.gov/products/plant-based-chronic-pain-treatment/protocol
April 01, 2023 - Moderate— We are moderately confident that the estimate of effect lies close to the true effect for this … Low— We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient— We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.
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effectivehealthcare-admin.ahrq.gov/products/kidney-stone-prevention/research-protocol
December 01, 2019 - link between intervention and outcome); and 4) precision (degree of certainty surrounding an effect estimate … A precise estimate is one that would yield a clinically meaningful conclusion. … of effect and may change the estimate. … that the evidence reflects the true effect; further research is likely to change confidence in the estimate … of effect and is likely to change the estimate.
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effectivehealthcare-admin.ahrq.gov/products/insomnia/research-protocol
December 01, 2019 - the overall strength of evidence for each outcome will be rated as: 39
High : Very confident that estimate … Moderate : Moderately confidence that estimate of effect lies close to true effect. … Low : Limited confidence that estimate of effect lies close to true effect; major or numerous deficiencies … Additional evidence necessary before concluding that findings are stable or that estimate of effect is … Insufficient : No evidence, unable to estimate an effect, or no confidence in estimate of effect.
-
effectivehealthcare-admin.ahrq.gov/products/nonopioid-chronic-pain/protocol
May 01, 2020 - least three studies reporting outcomes that are homogeneous enough to provide a meaningful combined estimate … Moderate— We are moderately confident that the estimate of effect lies close to the true effect for this … Low— We have limited confidence that the estimate of effect lies close to the true effect for this outcome … Insufficient— We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.