-
effectivehealthcare-admin.ahrq.gov/products/bipolar-disorder-treatment/research-protocol
December 01, 2019 - Prevalence studies estimate about 1 to 4% of the population has bipolar disorder, with relatively similar … Moderate : Moderately confidence that estimate of effect lies close to true effect. … Low : Limited confidence that estimate of effect lies close to true effect; major or numerous deficiencies … Additional evidence necessary before concluding that findings are stable or that estimate of effect is … Insufficient : No evidence, unable to estimate an effect, or no confidence in estimate of effect.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
February 01, 2019 - least three studies reporting outcomes that are
homogeneous enough to provide a meaningful combined estimate … • Moderate—We are moderately confident that the estimate of effect lies close to the true
effect for … • Low—We have limited confidence that the estimate of effect lies close to the true effect
for this … • Insufficient—We have no evidence, we are unable to estimate an effect, or we have no
confidence in … the estimate of effect for this outcome.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
January 28, 2019 - pertaining to each KQ will be classified into four categories:
1) High – We are very confident that the estimate … another study would not change the conclusions.
2) Moderate – We are moderately confident that the estimate … that additional evidence is needed before concluding either that the
findings are stable or that the estimate … of effect is close to the true effect.
4) Insufficient – We have no evidence, we are unable to estimate … an effect, or we have
no confidence in the estimate of the effect for this outcome.
-
effectivehealthcare-admin.ahrq.gov/products/multiple-sclerosis/research-protocol
December 01, 2019 - factors, the overall evidence for each outcome will be rated as: 16
High : Very confident that estimate … Moderate : Moderately confident that estimate of effect lies close to true effect. … Low : Limited confidence that estimate of effect lies close to true effect; major or numerous deficiencies … Additional evidence necessary before concluding that findings are stable or that estimate of effect is … Insufficient : No evidence, unable to estimate and effect, or no confidence in estimate of effect.
-
effectivehealthcare-admin.ahrq.gov/products/acute-pain-ems/protocol
February 01, 2019 - Moderate— We are moderately confident that the estimate of effect lies close to the true effect for this … Low— We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient— We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of the effect for this outcome.
-
effectivehealthcare-admin.ahrq.gov/products/osteoarthritis-pain/research-protocol
December 01, 2019 - ; the directness of the evidence linking the intervention and health outcomes; the precision of the estimate … reflects the true effect and that further research is very unlikely to change our confidence in the estimate … of effect and may change the estimate; (3) “low” grade indicates low confidence that the evidence reflects … the true effect and further research is likely to change the confidence in the estimate of effect and … is likely to change the estimate; (4) “insufficient” grade indicates evidence either is unavailable
-
effectivehealthcare-admin.ahrq.gov/products/weight-loss-surgery/research-protocol
December 01, 2019 - For trials that are judged sufficiently clinically similar to warrant meta-analysis, we will estimate … Further research is very unlikely to change our confidence on the estimate of effect. … Further research may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to change our confidence in the estimate of effect and is likely to change … the estimate.
-
effectivehealthcare-admin.ahrq.gov/products/chronic-pain-opioid-treatment/research-protocol
December 01, 2019 - Moderate — We are moderately confident that the estimate of effect lies close to the true effect for … Low — We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient — We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
October 01, 2022 - procedures
may cause seizure freedom in some infants; however, the precise proportion is too
variable to estimate … cause seizure freedom in some infants (SOE: Low);
however, the precise proportion is too variable to estimate
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol-amendment.pdf
February 04, 2025 - The four levels are:
• High—Very confident that the estimate of effect lies close to the true effect … • Moderate—Confident that the effect estimate lies close to the true effect for this outcome. … Additional
evidence is needed before concluding that the findings are stable or that the estimate of … Investigators are unable to estimate an effect or have no confidence
in the estimate of the effect of … Precision is the degree of certainty surrounding an effect estimate concerning a given
outcome, based
-
effectivehealthcare-admin.ahrq.gov/products/ems-blood-transfusion/protocol
February 01, 2025 - Moderate—Confident that the effect estimate lies close to the true effect for this outcome. … Low—Limited confidence that the estimate of effect lies close to the true effect for this outcome. … Additional evidence is needed before concluding that the findings are stable or that the estimate of … Investigators are unable to estimate an effect or have no confidence in the estimate of the effect of … Precision is the degree of certainty surrounding an effect estimate concerning a given outcome, based
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/mmm-draft-protocol-amendment.pdf
February 02, 2022 - consistency (similarity of
effect direction and size); 4) precision (degree of certainty around an estimate … An imprecise estimate is one for which the confidence interval is
wide enough to include clinically … ● Moderate: Moderately confident that estimate of effect lies close to true effect. … Additional evidence necessary before concluding that
findings are stable or that estimate of effect … ● Insufficient: No evidence, unable to estimate an effect, or no confidence in estimate of
effect
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
November 13, 2014 - consistency
(similarity of effect direction and size); (4) precision (degree of certainty around an
estimate … An imprecise estimate is one for which the confidence interval is wide enough to
include clinically … the overall strength of evidence for each outcome will be
rated as:41
• High: Very confident that estimate … Additional evidence
necessary before concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate an effect, or no confidence
in estimate of effect
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/telehealth-acute-chronic_research-protocol.pdf
February 15, 2017 - • Moderate—Confident that the estimate of effect lies close to the true effect for this
outcome. … • Low—Limited confidence that the estimate of effect lies close to the true effect for this
outcome … Investigators are unable to estimate an effect, or have no
confidence in the estimate of effect for … In this project DM will be used to estimate the
clinical and cost outcomes of telehealth consultations … for a selected clinical condition and to
estimate the impact of different payment models for telehealth
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
July 01, 2012 - The worse the
deviation of the reference test from the unobserved “truth,” the poorer the estimate of … More accurately, a study of diagnostic
accuracy tries to estimate quantities that are functions of the … The data in the 2 X 2 table are then sufficient to estimate the four remaining probabilities
(α1, β1 … Because the four probabilities necessarily sum to 1, it is sufficient to estimate
any three. … Note that the naïve estimate for the sensitivity and specificity of the index
test approach the true
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
December 17, 2013 - consistency (similarity of effect direction and size); and (4) precision (degree of
certainty around an estimate … • Moderate: Moderately confident that estimate of effect lies close to true effect. … • Low: Limited confidence that estimate of effect lies close to true effect; major or
numerous deficiencies … Additional evidence necessary before
concluding that findings are stable or that estimate of effect … • Insufficient: No evidence, unable to estimate and effect, or no confidence in
estimate of effect
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-draft-protocol.pdf
March 14, 2024 - and the initial study design, we will assign SOE rating as high,
moderate, low, or insufficient to estimate … High: We are very confident that the estimate of effect lies close to the true effect (the body
of evidence … Moderate: We are moderately confident that the estimate of effect lies close to the true effect
(the … Low: We have limited confidence that the estimate of effect lies close to the true effect (the
body … Insufficient: We are unable to estimate an effect or have no confidence in the estimate of
effect.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-executive-summary.pdf
November 01, 2024 - When more than two
studies were available, different designs and/or methods to calculate the estimate … Studies without a protein or amino acid requirement estimate (k=6) reported
outcomes such as growth,
-
effectivehealthcare-admin.ahrq.gov/products/cervical-degenerative-disease/research
February 01, 2024 - that the evidence reflects the true effect; further research is likely to change our confidence in the estimate … of the effect and is likely to change the estimate. … of the effect and may change the estimate. … evidence reflects the true effect; further research is very unlikely to change our confidence in the estimate … Studies should also estimate the minimally important between-group differences for included outcomes
-
effectivehealthcare-admin.ahrq.gov/products/bladder-cancer-muscle-invasive/research-protocol
December 01, 2020 - precise estimates on outcomes for which studies are similar enough to provide a meaningful combined estimate … Moderate — We are moderately confident that the estimate of effect lies close to the true effect for … Low — We have limited confidence that the estimate of effect lies close to the true effect for this outcome … Insufficient — We have no evidence, we are unable to estimate an effect, or we have no confidence in … the estimate of effect for this outcome.