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effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
April 01, 2012 - Clinical cardiovascular effectiveness/
efficacy outcomes (e.g., mortality and specific
cardiovascular … • Reported clinical or surrogate cardiovascular efficacy
or harms, or pharmacokinetic outcomes, in … efficacy studies.29
Data Synthesis and Analysis
All analyses compared the combination of dietary … Most studies were
short-term efficacy trials. … A simple and valid
tool distinguished efficacy from effectiveness studies.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
November 01, 2012 - Key Questions not only addressed short-term
efficacy and safety but also assessed longer term benefits … Inclusion and Exclusion Criteria
For treatment efficacy, we included studies if they were
RCTs that … Key Points
• RCT results were limited to short-term efficacy studies
versus placebo or usual care ( … There was no evidence of a difference in
treatment efficacy between these two agents. … Efficacy and
safety of pramipexole in restless legs syndrome.
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Two clinical trials, investigating optimal doses of intranasal esketamine for MDD
and efficacy for … They were encouraged by reported clinical trial data demonstrating
broad efficacy, but noted a dearth … If intravenous scopolamine has superior efficacy, experts thought, its use would have
some impact on … Replication of ketamine's antidepressant efficacy
in bipolar depression: a randomized controlled … Antidepressant efficacy of ketamine in
treatment-resistant major depression: a two-
site randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1512.pdf
December 01, 2015 - within 0–3 years of potential diffusion (e.g., in
phase III trials or for which some preliminary efficacy … Based on available efficacy and diffusion data, experts’ comments indicated that
ES-4
off-label … Some clinical interventions also solicit patient feedback on perceived program
tolerability and efficacy … limited patient-interaction components; published
data from these trials show varied intervention efficacy … , but failed to demonstrate broad value for multiple patient populations or long-term efficacy
for
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-cardio-dental.pdf
July 01, 2023 - Rapid Response: Efficacy of Dental Services for Reducing Adverse Events in Those Undergoing Insertion … of Implantable Cardiovascular Devices
Rapid Response
July 2023
Efficacy of Dental Services … A systematic review19 sought studies examining the efficacy of dental care prior to either
surgical … Our MEDLINE search identified no primary studies or systematic
reviews on the efficacy of dental care … Suggested language for
acknowledgment: This work was based on an evidence report, Efficacy of Dental
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
January 01, 2009 - management in low-risk, full-term planned vaginal deliveries, including maternal and
child health outcomes, efficacy … as opioids), other inhalational agents, non-pharmacologic methods of
pain management
Outcome(s): efficacy
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0108_05-24-2009.pdf
January 01, 2009 - The more specific topic of the efficacy of IV Benadryl, Toradol, and Reglan in an emergency … reviews caution against the
use of opioids as first-line treatment for migraine because of lack of efficacy
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
March 01, 2014 - , and patient
outcome efficacy of instruments used to assess cough? … or patient outcome
efficacy of these tools. … We did not identify any studies evaluating
the comparative therapeutic efficacy or patient outcome … The effect of moguisteine was too imprecise to draw
conclusions about is efficacy. … or patient outcome
efficacy.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
February 01, 2016 - Focus of This Summary
This is a summary of a systematic review evaluating the evidence regarding the efficacy … Evidence from randomized,
placebo-controlled trials does not support the efficacy of disulfiram. … There was moderate-strength
evidence for the efficacy of topiramate (i.e., unapproved use under
the … Clinical Bottom Line
Table 1: Summary of Findings and Strength of Evidence for the Efficacy of Medications … having psychosocial cointerventions along
with taking the medications
�� Evidence related to the efficacy
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0623-140828.pdf
April 25, 2014 - The topic was nominated by an individual who is specifically interested in the safety and
Summary: efficacy … ART)
Outcome(s): Conception, pregnancy, and safety and efficacy
Key Questions What are the best options
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0405_01-16-2011.pdf
January 01, 2011 - For treatment efficacy: improvement in cough symptoms; cough severity; cough
counts; cough-related quality … What is the best way to assess cough severity and the efficacy of cough therapies?
2.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
December 30, 2015 - We did not identify eligible
trials assessing the efficacy of barbiturates or
diphenhydramine. … We aimed to assess the efficacy of the active
treatment when it was administered. … We report outcomes
measured at six months and over as sustained
efficacy. … and longterm efficacy. … There is no consideration of duration of
efficacy in the results section.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - , and patient
outcome efficacy) of available clinical and imaging tools for predicting thromboembolic … , and patient
outcome efficacy) of clinical tools and associated risk factors for predicting bleeding … thinking efficacy
Therapeutic efficacy
Patient outcome efficacy
• Timing:
Not applicable … for
predicting thromboembolic risk and bleeding events:
o Diagnostic accuracy efficacy
o Diagnostic … thinking efficacy
o Therapeutic efficacy
o Patient outcome efficacy
Timing • Timing of followup
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
September 01, 2011 - Peer Reviewer
#7
Introduction This CE review summarizes the CE data on the efficacy,
effectiveness … BA 25) has substantial
efficacy in experimental studies, yet this is not described. … Source: www.effectivehealthcare.ahrq.gov
11
efficacy endpoint of remission, measured using the … Peer Reviewer
#11
General The review appears to ignore the wealth of evidence about the
efficacy … This is
a serious limitation of this work since it ignores the wealth of data on
the efficacy of ECT
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
September 01, 2017 - o Original conclusions are likely current for efficacy and comparative effectiveness of medications … o Original conclusions are likely current for efficacy and comparative effectiveness. … o 1a: Efficacy conclusions are likely current for medications approved for use. … o 2a: Efficacy: Original conclusions are likely current. … Disulfiram efficacy in the treatment of alcohol dependence: a meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
September 01, 2019 - We were unable to draw conclusions about
the efficacy of opioids compared with nitrous oxide
(based … Efficacy of intravenous paracetamol versus intravenous
morphine in acute limb trauma. … Analgesic efficacy
of intranasal ketamine versus intranasal fentanyl for
moderate to severe pain in … Comparing the analgesic efficacy of morphine
plus ketamine versus morphine plus placebo in
patients … Comparison of clinical efficacy of intravenous
acetaminophen with intravenous morphine in acute
renal
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/living-systematic-reviews-full-text-articles-white-paper.pdf
January 01, 2024 - Safety and
efficacy of low-dose Medical Cannabis oils
in Multiple Sclerosis. … Cannabis extract CT-921 has a high
efficacy– adverse effect profile in a
neuropathic pain model. … Safety and efficacy of medical
cannabis in fibromyalgia. … Safety and
efficacy of low-dose medical cannabis oils
in multiple sclerosis. … Safety and efficacy of medical
cannabis in fibromyalgia.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
April 01, 2020 - Uncertainty persists
regarding their overall efficacy and
variations in efficacy by age and disorder … The SR examined efficacy and
comparative effectiveness of nonpharmacological,
pharmacological, and … A double-blind
efficacy and safety study of duloxetine fixed doses in
children and adolescents with … A double-blind
efficacy and safety study of duloxetine flexible dosing in
children and adolescents … A randomized, double-blind,
placebo-controlled evaluation of the safety and
efficacy of citalopram
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
March 01, 2019 - None of the trials were powered to evaluate harms
as they were all designed to assess efficacy. … Efficacy
of citalopram in the prevention of recurrent depression
in elderly patients: placebo-controlled … Comparative efficacy
and safety of sertraline versus nortriptyline in major
depression in patients … Efficacy and
tolerability of venlafaxine in geriatric outpatients
with major depression: a double-blind … Comparative
efficacy of sertraline vs. fluoxetine in patients age 70 or
over with major depression.
-
effectivehealthcare.ahrq.gov/products/atypical-antipsychotics-off-label/research