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Showing results for "efficacy".

  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
    April 01, 2012 - Clinical cardiovascular effectiveness/ efficacy outcomes (e.g., mortality and specific cardiovascular … • Reported clinical or surrogate cardiovascular efficacy or harms, or pharmacokinetic outcomes, in … efficacy studies.29 Data Synthesis and Analysis All analyses compared the combination of dietary … Most studies were short-term efficacy trials. … A simple and valid tool distinguished efficacy from effectiveness studies.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
    November 01, 2012 - Key Questions not only addressed short-term efficacy and safety but also assessed longer term benefits … Inclusion and Exclusion Criteria For treatment efficacy, we included studies if they were RCTs that … Key Points • RCT results were limited to short-term efficacy studies versus placebo or usual care ( … There was no evidence of a difference in treatment efficacy between these two agents. … Efficacy and safety of pramipexole in restless legs syndrome.
  3. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Two clinical trials, investigating optimal doses of intranasal esketamine for MDD and efficacy for … They were encouraged by reported clinical trial data demonstrating broad efficacy, but noted a dearth … If intravenous scopolamine has superior efficacy, experts thought, its use would have some impact on … Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled … Antidepressant efficacy of ketamine in treatment-resistant major depression: a two- site randomized
  4. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - within 0–3 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … Based on available efficacy and diffusion data, experts’ comments indicated that ES-4 off-label … Some clinical interventions also solicit patient feedback on perceived program tolerability and efficacy … limited patient-interaction components; published data from these trials show varied intervention efficacy … , but failed to demonstrate broad value for multiple patient populations or long-term efficacy for
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-cardio-dental.pdf
    July 01, 2023 - Rapid Response: Efficacy of Dental Services for Reducing Adverse Events in Those Undergoing Insertion … of Implantable Cardiovascular Devices Rapid Response July 2023 Efficacy of Dental Services … A systematic review19 sought studies examining the efficacy of dental care prior to either surgical … Our MEDLINE search identified no primary studies or systematic reviews on the efficacy of dental care … Suggested language for acknowledgment: This work was based on an evidence report, Efficacy of Dental
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0122_06-29-2009.pdf
    January 01, 2009 - management in low-risk, full-term planned vaginal deliveries, including maternal and child health outcomes, efficacy … as opioids), other inhalational agents, non-pharmacologic methods of pain management Outcome(s): efficacy
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0108_05-24-2009.pdf
    January 01, 2009 -  The more specific topic of the efficacy of IV Benadryl, Toradol, and Reglan in an emergency … reviews caution against the use of opioids as first-line treatment for migraine because of lack of efficacy
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
    March 01, 2014 - , and patient outcome efficacy of instruments used to assess cough? … or patient outcome efficacy of these tools. … We did not identify any studies evaluating the comparative therapeutic efficacy or patient outcome … The effect of moguisteine was too imprecise to draw conclusions about is efficacy. … or patient outcome efficacy.
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
    February 01, 2016 - Focus of This Summary This is a summary of a systematic review evaluating the evidence regarding the efficacy … Evidence from randomized, placebo-controlled trials does not support the efficacy of disulfiram. … There was moderate-strength evidence for the efficacy of topiramate (i.e., unapproved use under the … Clinical Bottom Line Table 1: Summary of Findings and Strength of Evidence for the Efficacy of Medications … having psychosocial cointerventions along with taking the medications �� Evidence related to the efficacy
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0623-140828.pdf
    April 25, 2014 - The topic was nominated by an individual who is specifically interested in the safety and Summary: efficacy … ART) Outcome(s): Conception, pregnancy, and safety and efficacy Key Questions What are the best options
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0405_01-16-2011.pdf
    January 01, 2011 - For treatment efficacy: improvement in cough symptoms; cough severity; cough counts; cough-related quality … What is the best way to assess cough severity and the efficacy of cough therapies? 2.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_disposition-comments.pdf
    December 30, 2015 - We did not identify eligible trials assessing the efficacy of barbiturates or diphenhydramine. … We aimed to assess the efficacy of the active treatment when it was administered. … We report outcomes measured at six months and over as sustained efficacy. … and longterm efficacy. … There is no consideration of duration of efficacy in the results section.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
    January 30, 2012 - , and patient outcome efficacy) of available clinical and imaging tools for predicting thromboembolic … , and patient outcome efficacy) of clinical tools and associated risk factors for predicting bleeding … thinking efficacy  Therapeutic efficacy  Patient outcome efficacy • Timing: Not applicable … for predicting thromboembolic risk and bleeding events: o Diagnostic accuracy efficacy o Diagnostic … thinking efficacy o Therapeutic efficacy o Patient outcome efficacy Timing • Timing of followup
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
    September 01, 2011 - Peer Reviewer #7 Introduction This CE review summarizes the CE data on the efficacy, effectiveness … BA 25) has substantial efficacy in experimental studies, yet this is not described. … Source: www.effectivehealthcare.ahrq.gov 11 efficacy endpoint of remission, measured using the … Peer Reviewer #11 General The review appears to ignore the wealth of evidence about the efficacy … This is a serious limitation of this work since it ignores the wealth of data on the efficacy of ECT
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
    September 01, 2017 - o Original conclusions are likely current for efficacy and comparative effectiveness of medications … o Original conclusions are likely current for efficacy and comparative effectiveness. … o 1a: Efficacy conclusions are likely current for medications approved for use. … o 2a: Efficacy: Original conclusions are likely current. … Disulfiram efficacy in the treatment of alcohol dependence: a meta-analysis.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
    September 01, 2019 - We were unable to draw conclusions about the efficacy of opioids compared with nitrous oxide (based … Efficacy of intravenous paracetamol versus intravenous morphine in acute limb trauma. … Analgesic efficacy of intranasal ketamine versus intranasal fentanyl for moderate to severe pain in … Comparing the analgesic efficacy of morphine plus ketamine versus morphine plus placebo in patients … Comparison of clinical efficacy of intravenous acetaminophen with intravenous morphine in acute renal
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/living-systematic-reviews-full-text-articles-white-paper.pdf
    January 01, 2024 - Safety and efficacy of low-dose Medical Cannabis oils in Multiple Sclerosis. … Cannabis extract CT-921 has a high efficacy– adverse effect profile in a neuropathic pain model. … Safety and efficacy of medical cannabis in fibromyalgia. … Safety and efficacy of low-dose medical cannabis oils in multiple sclerosis. … Safety and efficacy of medical cannabis in fibromyalgia.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
    April 01, 2020 - Uncertainty persists regarding their overall efficacy and variations in efficacy by age and disorder … The SR examined efficacy and comparative effectiveness of nonpharmacological, pharmacological, and … A double-blind efficacy and safety study of duloxetine fixed doses in children and adolescents with … A double-blind efficacy and safety study of duloxetine flexible dosing in children and adolescents … A randomized, double-blind, placebo-controlled evaluation of the safety and efficacy of citalopram
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
    March 01, 2019 - None of the trials were powered to evaluate harms as they were all designed to assess efficacy. … Efficacy of citalopram in the prevention of recurrent depression in elderly patients: placebo-controlled … Comparative efficacy and safety of sertraline versus nortriptyline in major depression in patients … Efficacy and tolerability of venlafaxine in geriatric outpatients with major depression: a double-blind … Comparative efficacy of sertraline vs. fluoxetine in patients age 70 or over with major depression.
  20. effectivehealthcare.ahrq.gov/products/atypical-antipsychotics-off-label/research

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