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Total Results: 1,134 records

Showing results for "efficacy".

341. Disposition of Comments for CER 201 Effectiveness of Indoor Allergen Reduction in the Management of Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
     February 15, 2018 - Reduction seems to equate the lack of appropriate studies on single interventions with a lack of efficacy … As it is, the document makes it sound like the absence of studies equates with lack of efficacy, which … The efficacy of allergen avoidance in mite-sensitive patients was demonstrated in the 1980’s by the … However, for some interventions there is evidence demonstrating lack of efficacy as well. … Aside from age, there are other features that appear to be important in determining efficacy, so that

342. Fraenkel (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/fraenkel.pdf
     May 29, 2025 - Untitled Pie Chart contacting  the  following  labels:  Cancer, Infertility,  Infection,  Efficacy

343. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - One phase III trial is ongoing, evaluating pirfenidone’s long-term safety and efficacy in patients … Safety and efficacy of treatment with lumacaftor in combination with ivacaftor in patients with CF … Efficacy and safety of pirfenidone for idiopathic pulmonary fibrosis. … Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis. … New data demonstrate sustained long-term efficacy of OFEV on slowing disease progression and safety

344. Functional-Limitations-Horizon-Scan-High-Impact-1306 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/functional-limitations-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - within 0–4 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … Comments: The experts commenting on this topic stated that a well-tolerated oral agent with high efficacy … significant morbidity and disability, a large unmet need remains for new treatments with improved efficacy … Evidence to date of dimethyl fumarate’s modestly-improved efficacy against relapse and brain lesions … The device’s perceived complex nature, the existence of comparators, and limited safety and efficacy

345. Disposition of Comments for CER 212 Nonsurgical Treatments for Urinary Incontinence in Women (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-212-urinary-incontinence-disposition-comments.pdf
     August 08, 2018 - This is a condition where the women’s willingness to engage in a therapy overrides efficacy. … The efficacy data for a drug for urgency incontinence may be quite good but this doesn’t matter if … Future efficacy studies need to not only assess efficacy but measure a broader array of factors that … Safety and efficacy have not been determined for various patient populations such as pregnant women … This is especially important when clinicians are faced with situations where efficacy needs to be

346. Multiple-Sclerosis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
     April 01, 2015 - Unfortunately, the efficacy of MS treatments appears to correlate with the frequency and severity of … • Common reasons for discontinuing include side effects, uncertainty about or perceived lack of efficacy … Current treatment strategies for multiple sclerosis - efficacy versus neurological adverse effects. … PRISMS-4: long-term efficacy of interferon- beta-1a in relapsing MS. … Multiple sclerosis patients’ benefit-risk preferences: serious adverse event risks versus treatment efficacy

347. Methods-Guidance-Applicability Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
     January 01, 2011 - Monitoring practices or visit frequency not used in typical practice Efficacy studies with strict … pragmatic” or “practical” trials) are designed to give more broadly applicable results than more common efficacy … trials.35,36 If data from both efficacy and effectiveness studies are available, comparing findings … Translating efficacy into effectiveness in antiretroviral therapy: beyond the pill count. … A simple and valid tool distinguished efficacy from effectiveness studies.

348. Methods Guide Atkins (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methods_guide_atkins.pdf
     January 01, 2011 - Monitoring practices or visit frequency not used in typical practice Efficacy studies with strict … pragmatic” or “practical” trials) are designed to give more broadly applicable results than more common efficacy … trials.35,36 If data from both efficacy and effectiveness studies are available, comparing findings … Translating efficacy into effectiveness in antiretroviral therapy: beyond the pill count. … A simple and valid tool distinguished efficacy from effectiveness studies.

349. Antipsychotics-Children Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
     June 04, 2010 - • Wording has been changed to clarify that the CER will compare efficacy, effectiveness and safety … Question 1: What is the comparative efficacy or effectiveness of first and second generation antipsychotics … We will compare the efficacy and effectiveness of FDA-approved first generation and second generation … Criteria for Inclusion/Exclusion of Studies in the Review Study design For efficacy, we will include … For the questions on efficacy and effectiveness, we will conduct comprehensive searches in the following

350. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - within 0–4 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … 70% of patients with CF. 7 Additionally, the manufacturer is sponsoring a study to evaluate the efficacy … Forthcoming information regarding third-party payer coverage, patient copayments, real-world clinical efficacy … Additionally, if physicians observe limited efficacy in clinical practice they could be hesitant to

351. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
     January 01, 2015 - within 0–3 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … agreed on the need for effective T2DM treatments, citing patient adherence issues and the lack of efficacy … colleagues reported outcomes from 5- day, random-order, crossover studies assessing the safety and efficacy … APDS in the United States.7,21 The ASPIRE clinical trial was designed to evaluate the safety and efficacy … A study of the safety and efficacy of a new treatment for diabetic macular edema.

352. Management of Renal Masses and Localized Renal Cell Carcinoma: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_clinician.pdf
     July 01, 2017 - Allowing for multiple retreatments led to a more comparable efficacy rate for TA. … RR of recurrence 0.37 (0.15 to 0.89) RR of recurrence 1.21 (0.58 to 2.50) for studies of secondary efficacy … of TA (secondary efficacy refers to retreatment with TA) ��� Overall survival 13 (8,451) Better

353. Disposition of Comments_Comparative Effectiveness Review No. 264_Social and Structural Determinants of Maternal Morbidy and Mortality: An Evidence Map (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-264-maternal-morbidity-mortality-disposition-comments.pdf
     December 21, 2023 - As such, efficacy or effectiveness studies of interventions to improve maternal health were not in … We did specify that interventional research examining efficacy or effectiveness of an intervention … We did specify that interventional research examining efficacy or effectiveness of an intervention … We did specify that interventional research examining efficacy or effectiveness of an intervention … We did specify that interventional research examining efficacy or effectiveness of an intervention

354. Contrast-Induced Nephropathy (CIN): Current State of the Evidence on Contrast Media and Prevention of CIN (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
     August 01, 2016 - The other review assessed the evidence regarding the comparative efficacy of measures to prevent CIN … various patient factors (e.g., comorbidities, baseline kidney function) or contrast dose; and how the efficacy

355. Fleisher (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/fleisher.pdf
     January 01, 2010 - Increase awareness, knowledge, and skills • Increase access and utilization of services • Increase self-­‐efficacy … Spark new knowledge or interest • Provide referrals • Create social support and  improve self-­‐efficacy

356. Nonopioid Pharmacologic Treatments for Chronic Pain: Appendix G (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-apg.xlsx
     January 01, 2019 - Unclear Yes No No (25%); Yes Yes Fair Enteshari-Moghaddam 2019 Unclear No Yes Yes Unclear Unclear [for efficacy … Unclear Unclear Yes Yes Yes Yes No (27%); Yes Yes Fair Schnitzer 2004 Yes Yes Yes Yes Yes No for efficacy

357. Disposition of Comments for CER 211: Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-211-rheumatoid-arthritis-disposition-comments.pdf
     December 20, 2018 - Peer Reviewer #4 Evidence Summary Page 17, lines 49-51: how do you balance the higher efficacy … Because our report is a comparative effectiveness review, we did not focus on the general efficacy of … We agree that lack of adherence can have other reasons than harms (e.g., lack of efficacy). … NICE DSU Technical Support Document 7: Evidence Synthesis of Treatment Efficacy in Decision Making: … We agree that lack of adherence can have other reasons than harms (e.g., lack of efficacy).

358. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - within 0–4 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … The FDA has requested additional data supporting the efficacy of Probuphine, including:  The ability

359. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0094_04-09-2009.pdf
     January 01, 2009 - individuals with ASD who present with severe aggression and irritability, what is the comparative efficacy

360. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
     January 01, 2012 - III trials for pharmaceuticals or biotechnologies or in phase II or a trial with some preliminary efficacy … frequently seen injuries caused by HBOT, so the treatment is controversial not only on the basis of efficacy … oxygen poisoning, barotrauma, and blurred vision, despite very preliminary results showing some efficacy … colleagues reported results from a multicenter, randomized, double-blind controlled trial on the efficacy … have a great impact on the unmet need, but more information about the frequency of treatments and efficacy