Results

Total Results: 1,134 records

Showing results for "efficacy".

321. Disposition of Comments for CER 147 Menopausal Symptoms: Comparative Effectiveness of Therapies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
     March 05, 2015 - Efficacy of nonestrogenic hot flash therapies among women stratified by breast cancer history and tamoxifen … An analysis of the comparative efficacy of both low dose paroxetine and ospemifene, well-studied agents … Their focus on the lack of evidence on compounded HT (safety and efficacy) being used by millions of … The conclusion of the report that estrogen has the greatest efficacy compared with other agents for … Unclear to me why efficacy in terms of vasomotor sx could not also be expressed in terms of absolute

322. Blood-Clots-Hip-Knee-Surgery Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
     March 01, 2012 - orthopedic surgery (total hip or knee replacement, hip fracture surgery), what is the comparative efficacy … For efficacy outcomes in KQ 1, only placebo or control arms of RCTs and observational studies were … Studies meeting less than five criteria would be classified as efficacy trials and deemed to have less … Although RCTs and studies that used objective diagnostic means to confirm efficacy outcomes were included … VKAs but higher bleeding; worse efficacy vs. factor Xa inhibitors but lower bleeding).

323. Urinary-Incontinence-Treatment Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-treatment_research-protocol.pdf
     September 30, 2010 - We will analyze the harmful effects of drugs from all sources including efficacy, effectiveness, and … For questions 2 and 3, we will define efficacy and effectiveness trials following criteria from the … Clinical efficacy and safety of tolterodine in the treatment of overactive bladder: a pooled analysis … Efficacy and tolerability of fesoterodine in women with overactive bladder. … Comparative efficacy of behavioral interventions in the management of female urinary incontinence.

324. Psychological and Pharmacological Treatments for Adults with Posttraumatic (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment-update_research-protocol.pdf
     December 31, 2017 - for many clinical conditions; however, little published data exist on the efficacy of hypnosis in treating … Where one report found evidence to suggest efficacy of a particular treatment, another report deemed … the underlying evidence inadequate to address efficacy and, therefore, was unable to make a recommendation … help determine whether the change to DSM-5 criteria to diagnose PTSD has any implications for the efficacy … We feel that the results should not be used to make decisions about efficacy/effectiveness.

325. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_executive.pdf
     October 01, 2007 - For example, most patients in RCTs had preserved left ventricular function, so variations in the efficacy … Accordingly, comparative efficacy of CABG and PCI according to variations in coronary anatomy could not … AWESOME trials reported specific analyses: they found no significant differences in the comparative efficacy … comparative effectiveness of PCI and CABG would be feasible, as well as assessment of whether relative efficacy … are also needed to assess whether the availability of drug-coated stents has affected the comparative efficacy

326. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-anemia-update_research-protocol.pdf
     June 16, 2010 - studied and used clinically for more than a decade to treat various anemias; they have similar clinical efficacy … EPO), epoetin-alpha and beta, are available for the treatment of anemia, both with similar clinical efficacy … There are several evidence-based guidelines assessing the efficacy of erythropoietin for treating patients … Further, analyses of efficacy and safety are suggested, either assessed per the approved prescribing … The efficacy of rHuEPO in cancer-related anaemia. Br J Haematol 2003;121(1): 3-11. 10.

327. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1506.pdf
     December 01, 2015 - within 0–3 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … identified since the publication of the previous High Impact report, have demonstrated promising efficacy

328. Knowledge Brief #2 Methods and Measures of Public Deliberation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/knowledge-brief-2-methods-public-deliberation-130213.pdf
     February 01, 2013 - Civic-mindedness, capacity for civic engagement, engagement in the political process, sense of self-efficacy … , sense of empowerment, political efficacy and solidarity, and anticipated post-meeting activity related

329. Knowledge Brief #2 Methods and Measures of Public Deliberation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/knowledge-brief-2-methods-public-deliberation-130213.pdf
     February 01, 2013 - Civic-mindedness, capacity for civic engagement, engagement in the political process, sense of self-efficacy … , sense of empowerment, political efficacy and solidarity, and anticipated post-meeting activity related

330. Methods-Guidance-Reporting-Bias Methods (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
     November 01, 2013 - Lower drug efficacy was found in 46 percent of reanalyses, identical efficacy in 7 percent, and greater … efficacy in 46 percent. … Eighty-eight percent of the 48 trials measuring efficacy and 62 percent of 26 trials measuring harms … Publication bias in antipsychotic trials: An analysis of efficacy comparing the published literature … Selective publication of antidepressant trials and its influence on apparent efficacy.

331. Arthritis-Knee-Physical-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
     April 01, 2010 - emphasize the role of nonpharmacologic treatments.11,12,14 However, scant evidence exists for the efficacy … Published reviews do not examine and compare the efficacy of all physical therapy interventions available … A comprehensive efficacy review of physical therapy for knee OA is necessary. … evidence-based physical therapy recommendations for adults with knee OA by synthesizing published efficacy … • Comparator Analysis of efficacy: o No active treatment (sham stimulation) Analysis

332. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
     January 28, 2016 - within 0–3 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … That limited efficacy coupled with low incidence of dengue virus infection in the United States limit … Phase III trials have shown it to have broad and high efficacy (>85% SVR) against several HCV genotypes … Based on preliminary, short-term efficacy data from a single clinical trial, the experts generally … Efficacy and effectiveness of an rVSV- vectored vaccine expressing Ebola surface glycoprotein: Interim

333. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
     March 01, 2010 - We cannot consider only the efficacy of these agents but also need to consider their harms. … Consider this given the inverse linear relationship between human growth hormone efficacy and age, as … KQ 6: In patients with CF, how are efficacy, effectiveness, safety, or adverse events impacted by rhGH … KQ 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of treatment … Key question 7: In patients with CF, how do the efficacy, effectiveness, safety, or adverse events of

334. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label_executive.pdf
     January 01, 2007 - Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics Executive Summary … www.effectivehealthcare. ahrq.gov/reports/final.cfm Number 6 Effective Health Care 2 Conclusions Evidence on the efficacy … Efficacy outcomes favored risperidone and olanzapine, and tolerability outcomes favored quetiapine and … olanzapine or risperidone as monotherapy for women with PTSD; the evidence was inconclusive regarding efficacy … With few exceptions, there is insufficient high-grade evidence to reach conclusions about the efficacy

335. Supplemental Project To Assess the Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
     March 01, 2018 - Efficacy and safety of pregabalin for treating neuropathic pain associated with diabetic peripheral … Efficacy and safety of lacosamide in painful diabetic neuropathy. … Efficacy and safety of the alpha4beta2 neuronal nicotinic receptor agonist ABT-894 in patients with … Dextromethorphan and memantine in painful diabetic neuropathy and postherpetic neuralgia: efficacy … Efficacy and safety of mexiletine in the treatment of painful diabetic neuropathy.

336. Disposition of Comments for CER 168 Infantile Hemangioma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
     January 15, 2016 - While Timolol therapy is very promising for small superficial IH, its efficacy for larger and more bulky … I believe that the efficacy and safety of both of these agents is largely dependent upon the type of … The majority of literature regarding intralesional steroids is focused on efficacy. … Peer reviewer #3 Results I don’t think one can accurately compare the treatment efficacy between these … Peer reviewer #3 Results 6) Page ES-15 – in regards to Corticosteroid efficacy, this paragraph reports

337. Methods Guide for Medical Test Reviews Chapter 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-topics_methods.pdf
     July 01, 2012 - situation requires the assumptions that the same cases would be detected by both tests and that treatment efficacy … which generally classify medical test research into 6 different domains or phases, including technical efficacy … , diagnostic accuracy, diagnostic thinking efficacy, therapeutic efficacy, patient outcome, and societal

338. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
     July 01, 2009 - WACA with or without additional ablation lines compared their efficacy to maintain sinus rhythm. … Six RCTs compared the efficacy of one RFA technique with vs. without the addition of left-sided ablation … current literature are needed before more reliable inferences can be made concerning the longer term efficacy … are most likely to benefit from RFA and studies on different RFA approaches and techniques to improve efficacy

339. Major-Depressive-Disorder Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/major-depressive-disorder_research-protocol.pdf
     November 24, 2014 - Available evidence for MDD does not warrant choosing one SGA over another based on either greater efficacy … To date, however, little is known about the comparative efficacy and effectiveness or harms of psychological … Outcomes • Efficacy: response, remission, speed of response, speed of remission, relapse, quality … Comparative efficacy and safety of a once-daily dosage of hypericum extract STW3-VI and citalopram in … The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the

340. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
     December 01, 2010 - The long-term consequences of SGAs remain largely unknown.10 There is debate surrounding the efficacy … with Schizophrenia, Schizophrenia-related psychoses, or bipolar disorder, what is the comparative efficacy … We will compare the efficacy and effectiveness of commercially available FDA-approved FGAs and SGAs … For the questions on efficacy and effectiveness, we will conduct comprehensive searches in the following … Upcoming agents for the treatment of Schizophrenia: mechanism of action, efficacy and tolerability.