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Total Results: 1,134 records

Showing results for "efficacy".

301. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
     February 01, 2012 - What is the comparative efficacy or effectiveness of FGAs and SGAs for treating disorder- or illness- … Tables with the summary of findings for efficacy and safety are presented below. … majority of the studies in this body of evidence were small to moderate-sized RCTs that examined the efficacy … In particular, the median study duration of 8 weeks is insufficient to assess some long-term efficacy … the limitations of the current evidence: • Studies examining long-term (at least 6 months followup) efficacy

302. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
     July 18, 2011 - These agents are indicated for the acute treatment of migraine in adults; however, reduced efficacy … This CER will specifically examine the efficacy of metoclopramide and the phenothiazines and investigate … Inclusion criteria Study design Efficacy and effectiveness: RCTs and NRCTs. … For the key efficacy outcomes (e.g., complete elimination of pain in the ED, Visual Analog Scale score … Evidence for Each Key Question We will evaluate the overall strength of the evidence for key efficacy

303. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
     March 28, 2019 - Efficacy ad safety of antidepressants for treatment of depression in Alzheimer’s disease: a metaanalysis … Peer reviewer #5 Introduction P. 2, next paragraph, 1st sentence: “Evaluating antidepressant efficacy … Reviewer #1, American Psychiatric Association Introduction On p. 3, in the 3rd paragraph under Efficacy … Therefore, in some studies the questionable efficacy may be attributable to subtherapeutic doses and … Peer reviewer #6 General Given similar efficacy among first line antidepressants, having information

304. White Paper: Living Systematic Reviews: Practical Considerations for Adapting Scope and Communicating the Evolving Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/scope-communicating-evolving-evidence-white-paper_0.pdf
     June 01, 2025 - opioids, nonopioid medications, and nonpharmacological interventions, are associated with limited efficacy … NCT05224336 Psilocybin; Placebo (Niacin) 20 July 2023 Open-label Study to Assess the Safety and Efficacy … March 2023 Cannabis Versus Oxycodone for Pain Relief Cannabis; Oxycodone; Placebo 100 June 2023 Efficacy … Cannabinoids CBD oil (MPL-001); CBD+THC oil (MPL-005); Placebo oil 51 December 2023 Safety and Efficacy … Assessment of Efficacy and Tolerability of Medicinal Cannabinoids in Patients With Multiple Sclerosis

305. Disposition of Comments for Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
     April 22, 2013 - Peer Reviewer 1 Results Page 35, line 28 What is a mixed efficacy-effectiveness study? … A “mixed efficacy-effectiveness” study was intended to refer to studies assessed to have scores of … 3 to 5 on the efficacy-effectiveness scale. … The scores corresponding to efficacy, mixed, or effectiveness are defined in Table 8. … Regardless, are the authors of the review calling for studies of the efficacy or effectiveness of e.g

306. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - within 0–4 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … visual development. 4 In 2012, Colaizy and colleagues presented data from a study evaluating the efficacy … In 2010, Sullivan and colleagues presented data from a study evaluating the efficacy of an exclusively … Overall, experts agreed that although more safety and efficacy studies must be performed to determine

307. Meditation Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
     October 17, 2012 - The Key Questions KQ 1: What are the efficacy and harms of Meditation Programs on negative affect … KQ 2: What are the efficacy and harms of Meditation Programs on attention among those with a clinical … KQ 3: What are the efficacy and harms of Meditation Programs on health-related behaviors affected by … KQ4: What are the efficacy and harms of Meditation Programs on pain and weight among those with a clinical … due to the intervention as opposed to efficacy due to a nonspecific placebo type effect.

308. Project Name: (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_disposition-comments.pdf
     October 25, 2011 - For example, CPAP has high efficacy but variable effectiveness limited by compliance. … Surgery has efficacy that is lower in most cases but effectiveness equal to efficacy because there … We do not believe that we have conflated or confused efficacy and effectiveness. … CPAP demonstrates very good efficacy. … We do not believe that we have conflated or confused efficacy and effectiveness.

309. Disposition of Comments Report for CER 207 on PTSD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-207-ptsd-disposition-comments.pdf
     May 17, 2018 - If I've read this correctly, you did require RCTs for treatment efficacy/effectiveness, but allows … All KQ4 studies are RCTs with efficacy or effectiveness findings reported in either KQ1, KQ2, or KQ3 … We note that we only include findings when differences in efficacy or effectiveness are reported via … Various controls were used in some tables, but, generally speaking, efficacy in the table title means … Efficacy of pharmacotherapy and psychotherapy for adult psychiatric disorders: A systematic overview

310. CARDIOVASCULAR (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - Investigators observed primary efficacy event rates in the device and control groups of 2.3% and 3.8% … The PREVAIL trial evaluated safety and efficacy of the device compared to warfarin therapy with three … However, some experts noted insufficient information regarding long-term safety and efficacy. … The PREVAIL trial (n=407) evaluated safety and efficacy of the device compared with warfarin therapy … However, some noted insufficient information regarding long-term safety and efficacy.

311. Meditation Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/meditation_executive.pdf
     January 01, 2014 - What are the efficacy and harms of meditation programs on negative affect (e.g., anxiety, stress) and … What are the efficacy and harms of meditation programs on health-related behaviors affected by stress … What are the efficacy and harms of meditation programs on pain and weight among those with a clinical … Our team thought this was the most rigorous way to determine the efficacy of the interventions. … For this review, the comparisons with nonspecific active controls provided efficacy data, whereas

312. Tinnitus Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
     August 01, 2013 - Food Supplement Interventions A total of 16 unique studies (17 publications)12-28 evaluated the efficacy … When considering the individual types of interventions and efficacy with respect to TSQoL, the studies … Efficacy of repetitive transcranial magnetic stimulation for the treatment of refractory chronic tinnitus … Open ear hearing aids in tinnitus therapy: an efficacy comparison with sound generators. … MarkeTrak VIII: the prevalence of tinnitus in the United States and the self-reported efficacy of various

313. Disposition of Comments for Progestogens for Prevention of Preterm Birth (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
     September 07, 2012 - caproate when a sister agency of AHRQ, the FDA, has not approved this drug for reasons of safety and efficacy … Therefore, there appear to be differences in efficacy and safety. … This is the reason why the efficacy of 17-alpha hydroxyprogesterone caproate is questionable. … trial was exceedingly high, and raised questions about efficacy. … This is the reason why another randomized clinical trial is now in progress to test the efficacy and

314. Weight-Loss-Surgery Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_executive.pdf
     June 01, 2013 - The following studies were excluded: (1) studies that did not report any outcomes of efficacy, effectiveness … The overall strength of evidence for intervention efficacy was assessed by using guidance suggested … Taking into consideration the entire body of evidence, we rate the strength of evidence of efficacy … Thus, we have almost no data on long-term efficacy and safety. … Safety and efficacy of Roux-en-Y gastric bypass to treat type 2 diabetes mellitus in non-severely

315. Disposition of Comments for Treatments for Fibromyalgia in Adult Subgroups (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_disposition-comments.pdf
     January 26, 2015 - is not defined, yet policy makers use “efficacy” as a key driver in their formulas on what is covered … I suggest a definition of efficacy that includes minimally clinically significant change (Dworkin). … Given the limited efficacy of treatments overall, it is hard to see why sub-group treatments would have … While observational studies cannot tell one much about efficacy, they can tell us about whether these … Efficacy and Safety of Pregabalin in Patients with Fibromyalgia and Co-Morbid Depression Receiving

316. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/infectiousdisease_hi_impact.pdf
     December 01, 2013 - Researchers reported that these protease inhibitors increased efficacy so that 65% to 75% of patients … Experts speculated that the lack of efficacy in protecting women might be due to the drug’s inability … The study was stopped early due to lack of efficacy. … short-term efficacy. … A phase 2b, safety and efficacy study of Boceprevir in patients coinfected with HIV and Hepatitis

317. What are the comparative diagnostic accuracy, diagnostic thinking, therapeutic, and patient outcome efficacy of non-invasive tests for the risk stratification of patients with coronary artery disease? | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-are-the-comparative-diagnostic-accuracy-diagnostic-thinking-therapeutic-and-patient-outcome-efficacy-of-non-invasive-tests-for-the-risk-stratification-of-patients-with-coronary-artery-disease

318. Gibbons (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/gibbons.pdf
     January 01, 2010 - • Clinical effectiveness is dependant on efficacy at all “points of care” (ACO, PCMH, population health

319. Disposition of Comments Report for The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
     September 29, 2014 - is on clinical effectiveness, we are interested not just in outcomes associated with “ideal” use (efficacy … It provides an update on previous systematic reviews on the efficacy and safety of long-term opioids … Long-term opioid therapy for chronic non-cancer pain: A systematic review and meta-analysis of efficacy … results in Wild study: study not designed to measure efficacy primarily. 1. … Table 2 (Wild 2010): for clarity of efficacy results, consider restating to: mean pain intensity scores

320. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
     March 01, 2012 - New drugs and drug-delivery modalities are intended to optimize efficacy to enable patients to meet … However, experts noted that buccal insulin’s efficacy has not yet been conclusively demonstrated and … However, experts noted that buccal insulin’s efficacy has not yet been conclusively demonstrated … Experts expressed a desire for further data evaluating safety and efficacy of these modifications to … While experts deemed initial data on treatment efficacy promising, they expressed concerns regarding