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Showing results for "efficacy".

261. What is the efficacy and comparative effectiveness of pharmacological and nonpharmacological treatments for adults with schizophrenia What are the harms from pharmacological and nonpharmacological treatments for adults with… | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-efficacy-and-comparative-effectiveness-of-pharmacological-and-nonpharmacological-treatments-for-adults-with-schizophrenia-what-are-the-harms-from-pharmacological-and-nonpharmacological-treatments-for-adults-with-

262. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
     February 01, 2015 - within 0–3 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … Research into intranasal insulin’s efficacy for treating AD is being advanced by several academic and … Additionally, approved treatments are effective for only some AD patients, and efficacy decreases over … ., Lynnwood, WA), and nasal spray bottles.3,4,12,14,15 These clinical trials have also tested the efficacy … colleagues published multiple analyses from a clinical trial (n=104) investigating intranasal insulin efficacy

263. pneumonia-antibiotic-treatment-protocol-130718 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
     July 19, 2013 - The primary goals of clinical pharmacokinetics include enhancing efficacy and decreasing toxicity of … have shown conflicting results.18-20 For antibiotics in which the AUC/MIC ratio is the predictor of efficacy … These guidelines recommend a target AUC/MIC ratio of 400 for optimal efficacy of vancomycin. … dosage, and route of administration with the goal of maximizing treatment effectiveness to improve the efficacy … Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model

264. Evidence Summary: CER 231 Care Interventions for People Living With Dementia and Their Caregivers (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-231-dementia-interventions-evidence-summary_0.pdf
     August 01, 2020 - The vast majority of studies had small sample size, were pilots that had not undergone traditional efficacy … Only with such improvements will we be able to draw clearer, less ambiguous conclusions related to efficacy

265. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - Results – KQ2 My main concerns (specifically with Q2a) are the use of SMDs for the evaluation of efficacy … TEP #2 Results – KQ2 I don’t think a summary statement of opioid efficacy should be made based on … Otherwise, typical opioids are considered to be equivalent in efficacy for pain and have been treated … Similarly, were dropout rates due to lack of efficacy assessed? … We did not assess dropout rates due to lack of efficacy, as this would have been accounted for in the

266. Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
     March 24, 2017 - Results – KQ2 My main concerns (specifically with Q2a) are the use of SMDs for the evaluation of efficacy … TEP #2 Results – KQ2 I don’t think a summary statement of opioid efficacy should be made based on … Otherwise, typical opioids are considered to be equivalent in efficacy for pain and have been treated … Similarly, were dropout rates due to lack of efficacy assessed? … We did not assess dropout rates due to lack of efficacy, as this would have been accounted for in the

267. Topic Brief: Updating Pharmacotherapy for Adults with Alcohol Use Disorders in Outpatient Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/nt_docs/topic-brief-updating-pharmacotherapy.pdf
     September 30, 2022 - have also been tried for the treatment of AUD.53 However, due to limited evidence regarding their efficacy … Efficacy of Varenicline in Patients With Severe Alcohol Dependence: A Pilot Double-Blind Randomized … Long-term safety and efficacy of Nalmefene in Japanese patients with alcohol dependence. … Efficacy of Naltrexone for the Treatment of Alcohol Dependence in Latino Populations. … Self-efficacy mediates the effects of Topiramate and GRIK1 genotype on drinking.

268. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_june_2012.pdf
     January 01, 2012 - New drugs and drug-delivery modalities are intended to optimize efficacy to enable patients to meet … However, experts noted that buccal insulin’s efficacy has not yet been conclusively demonstrated and … However, experts noted that buccal insulin’s efficacy has not yet been conclusively demonstrated and … Most experts noted a lack of efficacy trials as a reason for skepticism over Oral-lyn’s ability to … Experts expressed a desire for further data evaluating safety and efficacy of these modifications to

269. Topic Brief: Nonpharmacologic Treatment of Mental Health Conditions in Pregnant and Postpartum People (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/nt_docs/1002-nonpharmacologic-treatment-topic-brief.pdf
     June 03, 2024 - The efficacy of cognitive behavioral therapy for the treatment of antenatal depression: A systematic … Efficacy of Prenatal Yoga in the Treatment of Depression and Anxiety during Pregnancy: A Systematic … Efficacy of rTMS in decreasing postnatal depression symptoms: A systematic review. … Efficacy of acupuncture versus sham acupuncture for postpartum depression disorder: Study protocol for … The efficacy of early iron supplementation on postpartum depression, a randomized double-blind placebo-controlled

270. Topic 0583 Renal Masses and Localized Renal Cancer NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0710-140625.pdf
     January 08, 2014 - overall survival), renal function, complications Key Questions What is the comparative oncologic efficacy

271. Disposition of Comments for Treatments for Seasonal Allergic Rhinitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_disposition-comments.pdf
     July 17, 2013 - ; uncontrolled studies are prone to increased risk of bias due to the subjective reporting of both efficacy … noncomparative studies are prone to increased risk of bias due to the subjective reporting of both efficacy … Similarly to the statement about efficacy above lack of evidence of increased harm is not equal to … for greater clarity: “This calls into question what is perhaps accepted wisdom about the greater efficacy … Evidence for efficacy of (1) combination intranasal corticosteroid plus oral selective antihistamine

272. Disposition of Comments for Psychological Treatments and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
     April 03, 2013 - It does not indicate that a treatment has been proven to lack efficacy.” 8 Anonymous Public Reviewer … The reconceptualization stems from the usefulness of hybridized efficacy and effectiveness research … A major and important treatment efficacy. … On the other hand, if it were 50, there is almost complete overlap, and no treatment efficacy. … When several different outcomes are reported, and they do not come to the same conclusion on efficacy

273. Acute Treatment for Episodic Migraine: Surveillance Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
     June 01, 2022 - For triptan insufficient responders (defined as patients who had poor or very poor treatment efficacy … Lasmiditan efficacy in the acute treatment of migraine was independent of prior response to triptans … Comparison of efficacy outcomes in trials using a M207 in the acute treatment of a single migraine … Efficacy of acupressure on intensity of acute migraine in patients attending an emergency department … Lasmiditan efficacy in mild versus moderate or severe migraine headaches (1811).

274. Disposition of Comments for Migraine in Adults: Preventive Pharmacologic Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
     April 18, 2013 - We revised the report clarifying the evidence from efficacy RCTs of individual drugs and from network … Comparative effectiveness trials should examine the drugs that had been shown efficacy (better than … safety but no efficacy report. to what purpose? … We reviewed RCTs and controlled clinical trials for drugs efficacy and comparative effectiveness. … We could not find RCTs or controlled clinical trials of botox efficacy in children.

275. Ptsd-Adults-Trauma-Interventions Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
     November 08, 2012 - Critical incident stress debriefing (CISD): Efficacy in question. NSPB. 2005;3(2):49-70. 16. … “Absolute effectiveness” has been replaced by “efficacy”. … “Absolute effectiveness” has been replaced by “efficacy”. … “Absolute effectiveness” has been replaced by “efficacy”. … “Absolute effectiveness” has been replaced by “efficacy”.

276. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
     January 10, 2012 - In 2008, Schmitt and colleagues published a meta-analysis analyzing the efficacy and tolerability of … Based on the results of their meta-analysis, the authors concluded that the efficacy of systemic agents … As suggested in the public comments, we will consider when evaluating efficacy data whether patients … Synthesis KQs 1 and 2 explore the efficacy and safety of three classes of therapy for the treatment … Efficacy and safety results from the randomized controlled comparative study of adalimumab vs.

277. Asthma-Immunotherapy-2010 Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2010_research-protocol.pdf
     January 01, 2010 - of the patient’s immune system.4,17-20,22 Controlled clinical trials have demonstrated therapeutic efficacy … induce a beneficial clinical effect) have either decreased or increased in tandem with no resultant efficacy … Short- and long-term efficacy and effectiveness. … Outcomes for KQs 1 and 3 KQ 1 evaluates efficacy and effectiveness of SIT, and KQ 3 evaluates the … Efficacy of Allervax® ragweed in the treatment of ragweed-induced allergy.

278. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1306.pdf
     January 01, 2016 - But the experts called for longer safety and efficacy studies to determine whether this system would … Another clinical expert mentioned this drug’s potential efficacy, shown in two phase III trial results … Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to … Efficacy and safety of exenatide once weekly versus metformin, pioglitazone, and sitagliptin used … Two-year safety and efficacy of ranibizumab 0.5 mg in diabetic macular edema: interim analysis of

279. Chronic-Urinary-Retention Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-urinary-retention_research.pdf
     September 01, 2014 - Two small RCTs studied efficacy and comparative effectiveness of CUR interventions in populations with … Efficacy of sacral nerve stimulation for urinary retention: results 18 months after implantation. … conducted a systematic review evaluating the efficacy of sacral neuromodulation with implanted devices … All four studies were efficacy trials. … Efficacy of sacral nerve stimulation for urinary retention: results 18 months after implantation.

280. Disposition of Comments for Pulmonary Arterial Hypertension: Screening, Management, and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
     April 25, 2013 - This stepwise addition of therapy does not test the efficacy of combination versus monotherapy. … Public Reviewer - ACCP 6 Results The assessment of drug efficacy presents another constellation of … Public Reviewer - ACCP 9 Results p.98: “…we would infer efficacy of tadalfil from controlled trials … Previous studies have been designed to examine short term efficacy of particular treatments. … We identified 3 RCTs that evaluated the efficacy of tadalafil (Table 23).