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effectivehealthcare.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
April 17, 2012 - Only one surgical treatment has definitively demonstrated long-term efficacy for morbidly obese
patients … Experts also opined that
further studies evaluating efficacy and safety are needed. … Regardless of the potential treatment efficacy, the EndoBarrier appears to have significant potential … A
multicenter, randomized efficacy study of the
EndoBarrier Gastrointestinal Liner for presurgical … Safety and efficacy study of
EndoBarrier in subjects with type II diabetes and
obesity.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
September 26, 2014 - Experts commenting on this intervention cited a limited amount of safety
and efficacy data. … However, some experts questioned long-term efficacy and
thought this intervention should be reserved … The ASPIRE study reportedly met
safety and efficacy endpoints and provided clinical validation for … Some cited the lack of long-term efficacy studies as potential
barriers for clinicians and patients … A study of the safety and efficacy of a
new treatment for diabetic macular edema.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer30_hip-fracture-pain-executive-summary_20110517.pdf
May 01, 2011 - KQ 4: Efficacy, effectiveness, and safety in
subpopulations. No data were reported. … KQ 4: Efficacy, effectiveness, and safety in
subpopulations. No data were reported. … KQ 4: Efficacy, effectiveness, and safety in
subpopulations. No data were reported. … KQ 4: Efficacy, effectiveness, and safety in
subpopulations. No data were reported. … KQ 4: Efficacy, effectiveness, and safety in
subpopulations.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-adults-prisons_executive.pdf
August 01, 2013 - Four trials tested the efficacy of pharmacologic therapies. … More
research is needed to better assess the efficacy of these
treatments. … One trial is testing the efficacy of
paliperidone palmitate compared with the efficacy of oral
antipsychotic … The second trial is comparing the efficacy
of MTC reentry compared with the efficacy of case
management … However,
one ongoing trial is testing the efficacy of forensic
assertive community treatment (FACT)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
October 30, 2019 - Efficacy and safety of dabigatran
compared to warfarin in patients with paroxysmal,
persistent, and … It is not clear to me what is the difference
between therapeutic efficacy and patient outcome
efficacy … , therapeutic
efficacy, and patient outcome
efficacy. … Recommendation: Based on the evidence, all
DOACS have shown safety and efficacy in patients
who are … Efficacy and safety
of rivaroxaban compared with warfarin in patients
with peripheral artery disease
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effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
January 01, 2012 - within 0–4 years of potential diffusion (e.g., in
phase III trials or for which some preliminary efficacy … Only one surgical treatment (gastric bypass surgery) has definitively demonstrated long-term
efficacy … While
preliminary results are promising, further studies evaluating efficacy and safety are needed, … A
multicenter, randomized efficacy study of the
EndoBarrier gastrointestinal liner for presurgical … Safety and efficacy study of
EndoBarrier in subjects with type II diabetes and
obesity.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-literacy_research-protocol.pdf
January 22, 2010 - Self-efficacy: Self-efficacy, a person’s confidence in their ability to carry out a
health behavior … Several researchers have
hypothesized a link between self-efficacy and literacy. … Literacy and its relationship with self-efficacy, trust, and
participation in medical decision making … Is self-efficacy associated with diabetes self-management
across race/ethnicity and health literacy? … Literacy, self-efficacy, and HIV medication adherence.
Patient Educ Couns 2007;65:253-60.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
May 01, 2022 - Efficacy and safety of two fixed-dose
combinations of tramadol hydrochloride and
diclofenac sodium … Efficacy
of routinely used analgesics in management
of pulpal pain postoperatively a clinical
study … Efficacy and safety of two fixed-dose
combinations of tramadol hydrochloride and
diclofenac sodium … Efficacy, acceptability, and safety of muscle
D-3
relaxants for adults with non-specific low … Evaluation of the efficacy of liposomal
bupivacaine in total joint arthroplasty.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
May 08, 2013 - Only RCT's were included for evaluating
efficacy of preventive interventions, so cohort studies were … Do not conflate
efficacy and effectiveness criteria – this is a comparative
effectiveness review so … These distinctions (quality; efficacy vs. … For Table 7, we agree that the terms "efficacy" and
"comparative effectiveness" were confusing. … In fact we did
not mean to use the terms "efficacy" and "effectiveness" to
distinguish trials that
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
December 01, 2015 - within 0–3 years of potential diffusion (e.g., in
phase III trials or for which some preliminary efficacy … Although evidence confirming the efficacy of antiamyloidogenic (amyloid-beta aggregation-
targeting) … testing, despite initial analysis of intermediate doses used in phase I testing
showing no clinical efficacy
-
effectivehealthcare.ahrq.gov/sites/default/files/s13.pdf
October 01, 2007 - become clear that the
information available at the time of drug marketing is
sufficient to prove drug efficacy … Post-marketing studies of drug
efficacy: why? Am J Med. 1985;78:475–480.
4. … Postmarketing studies of drug
efficacy: when must they be randomized?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation-future_research.pdf
January 01, 2013 - Addressing
these issues will enhance understanding of efficacy and comparative effectiveness, which … Specifically, we found insufficient evidence to assess efficacy or
effectiveness, and identified few … 2.3
Tier 3: Low Priority
Subgroups: Does the efficacy of specific multidisciplinary rehabilitation … Facilitators will utilize approaches
aimed at maximizing participant self-efficacy, reducing barriers … A randomized wait-list control group design will
be used to evaluate the efficacy of the intervention
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_disposition-comments.pdf
January 27, 2014 - 2 It is not
appropriate to use
reimbursement categories to
describe results that measure
efficacy … As
well, at the conclusion of the
study, the data must
demonstrate both safety and
efficacy to merit … This has clearly impacted
the quality of potential efficacy data.” … The
data demonstrated safety and
efficacy in healing patients
with VLUs in ulcers greater
than 1 … As
stated previously, the Apligraf
pivotal study was only
designed to test safety and
efficacy in
-
effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_2012-12-10.pdf
January 01, 2012 - New drugs and drug-
delivery modalities are intended to optimize efficacy to enable patients to meet … However, experts noted that
buccal insulin’s efficacy has not yet been conclusively demonstrated and … However, experts noted that buccal insulin’s efficacy has not yet been conclusively
demonstrated and … Most
experts noted a lack of efficacy trials as a reason for skepticism over Oral-lyn’s ability to … Efficacy and
safety of exenatide once weekly versus liraglutide
in subjects with type 2 diabetes
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar_research.pdf
August 01, 2015 - Study design:
Allocation: Randomized
Endpoint Classification:
Safety/Efficacy Study
Intervention … Study design:
Allocation: Randomized
Endpoint Classification: Efficacy
Study
Intervention Model: … Study design:
Allocation: Randomized
Endpoint Classification: Efficacy
Study
Intervention Model: … Study design:
Allocation: Randomized
Endpoint Classification: Efficacy
Study
Intervention Model: … Study design:
Allocation: Randomized
Endpoint Classification:
Safety/Efficacy Study
Intervention
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_surveillance.pdf
April 01, 2012 - another treatment as significantly superior to the one evaluated in the original
review, based on efficacy … B, four quality C) with largely null
findings did not support any substantive
differences in the efficacy … The RCT showed
equivalency but non-superiority
(except for average leak values)
in efficacy, adherence … Devices
The strength of evidence is insufficient to draw
conclusions with regard to the relative efficacy … Prospective trial of efficacy and safety of
ondansetron and fluoxetine in patients with
obstructive
-
effectivehealthcare.ahrq.gov/sites/default/files/study-eligibility-criteria.ppt
January 01, 2000 - Studies To Be Included
Limiting a review to randomized controlled trials is appropriate for questions of efficacy … Exercise 2:
Selecting Criteria for a Narrow Research Question
What is the efficacy of home uterine activity … Notice that the question focuses on “efficacy” (which suggests the inclusion of randomized controlled … Exercise 2: Implications of a Question That Requires Narrow Criteria
Efficacy: randomized controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0264_01-14-2008.pdf
January 01, 2008 - Excluded drugs (rarely or very infrequently used): penicillamine (toxicity), oral gold
(marginal efficacy
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0663-131114.pdf
April 10, 2013 - Bipolar disorder is a difficult illness to treat as available treatments have differential efficacy
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0496_12-30-2011.pdf
January 01, 2011 - What is the comparative efficacy of different therapies in preventing contrast-
induced nephropathy?