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Total Results: 1,134 records

Showing results for "efficacy".

201. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1406.pdf
     January 01, 2020 - within 0–3 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … Experts wanted to see additional clinical trial data assessing baclofen’s long-term safety and efficacy … The program aims to boost efficacy through coordinating and integrating existing community efforts, … Project Lazarus reported preliminary efficacy data from 2009 and 2010 for Wilkes County, demonstrating … Efficacy of intranasal naloxone as a needleless alternative for treatment of opioid overdose in the

202. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
     February 17, 2016 - undergoing total hip replacement, total knee replacement, or hip fracture surgery; the comparative efficacy … orthopedic surgery (total hip or knee replacement, hip fracture surgery), what is the comparative efficacy … orthopedic surgery (total hip or knee replacement, hip fracture surgery), what is the comparative efficacy … orthopedic surgery (total hip or knee replacement, hip fracture surgery), what is the comparative efficacy … orthopedic surgery (total hip or knee replacement, hip fracture surgery), what is the comparative efficacy

203. Gout-managment-protocol-141103 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol.pdf
     November 03, 2014 - The evidence for the efficacy of specific dietary changes in managing gout (preventing flares) is a … Early initiation of treatment (KQ 1, 2, 3) • Outcomes: o For acute gout treatment (KQ1) § Efficacy … chronic gout treatment (uric acid lowering therapy), monitoring, and discontinuation (KQ3-5) § Efficacy … For studies of efficacy and effectiveness, we will limit the inclusion to randomized controlled trials … randomized controlled trials for an intervention of interest, we may consider observational studies of efficacy

204. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
     August 05, 2010 - In addition, efficacy and safety may vary for individual drugs within a class. … comparative effectiveness review (CER) is to update the previous report that assessed the comparative efficacy … We will include studies that evaluate the safety, efficacy or effectiveness of the previously mentioned … duration); method of outcome ascertainment if available, and results for each outcome, focusing on efficacy … Studies could receive one rating for assessment of efficacy and a different rating for assessment of

205. Disposition of Comments Report for Stroke Prevention in Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
     August 23, 2013 - Most trials reported primary efficacy endpoints in an ITT population. … This disparity in INR control likely affects the overall relative efficacy of an anticoagulant when … In addition, apixaban in particular showed safety and efficacy when compared to aspirin in patients … We have now reported the ITT results for the primary efficacy outcome of the ROCKET-AF trial before … 75) and younger patients for both efficacy and safety.

206. Acs-Pci-Adjunctive-Devices Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
     July 01, 2010 - agents—including glycoprotein IIb/IIIa receptor inhibitors and thienopyridines—have improved the efficacy … Minneapolis, MN) even being shown to increase MACE when compared to a control.4 Thus, the comparative efficacy … follow-up duration (<6 months vs. ≥6 months and publication type (full-text vs. abstract only) on the efficacy … used intention-to-treat analysis.11 Studies meeting fewer than five criteria would be classified as efficacy … A simple and valid tool distinguished efficacy from effectiveness studies.

207. Intermittent Inhalded Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-evidence-summary-corticosteroids-asthma.pdf
     October 01, 2017 - Advisory Council Asthma Expert Working group.1 The objectives of the systematic review are: • To assess efficacy … years and older with persistent asthma (with or without long-acting beta agonist (LABA) • To assess efficacy … controller therapy for persistent asthma in patients of all ages.1 Purpose of Review To assess the efficacy

208. CER 218 Evidence Summary: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-fracture-prevention-evidence-summary.pdf
     April 01, 2019 - used for research purposes, but should not be considered current. 2 Despite the evidence on the efficacy … Variation in Efficacy as a Function of Patient, Bone, or Osteoporosis Drug Characteristics Efficacy … Evidence on efficacy of long-term (>3 years) osteoporosis drug treatment Comparison # Studies by Design … Evidence on efficacy of long-term (>3 years) osteoporosis drug treatment (continued) 6 Comparison … Evidence on efficacy of long-term (>3 years) osteoporosis drug treatment (continued) Harms Due to

209. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - within 0–3 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … Internet by a company in Boise, ID (ABC Nutriceuticals, Inc.), although information on safety and efficacy … nucleus accumbens.5-8 Based on these findings, clinical trials are examining oxytocin’s safety and efficacy … from at least one company, ABC Nutriceuticals, Inc., Boise, ID, although information on safety and efficacy … Overall, experts noted that this intervention needs more data to show its efficacy and long-term effects

210. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
     February 10, 2010 - Does the efficacy and/or effectiveness of breathing techniques for asthma health outcomes differ between … Does the efficacy and/or effectiveness of breathing techniques for asthma health outcomes differ according … Does the efficacy and/or effectiveness of breathing techniques for other asthma outcomes differ between … Does the efficacy and/or effectiveness of breathing techniques for other asthma outcomes differ according … more extensively in non- highly developed countries (particularly yoga in India), so evidence on efficacy

211. Research Protocol: Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/safety-vaccines-protocol.pdf
     January 30, 2020 - Update on vaccination of preterm infants: a systematic review about safety and efficacy/effectiveness … Efficacy and safety of pertussis vaccination for pregnant women - a systematic review of randomised … Influenza and Pneumococcal Vaccination in Hematological Malignancies: a Systematic Review of Efficacy … Efficacy and effectiveness of high-dose versus standard-dose influenza vaccination for older adults: … Efficacy, effectiveness, and safety of herpes zoster vaccines in adults aged 50 and older: systematic

212. Palliative radiation therapy for bone metastases: Update of an ASTRO Evidence-Based Guideline (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-bone-metastases.pdf
     February 01, 2017 - Series from Gutierrez Bayard,7 Howell,1 and Majumder8 all evaluated the efficacy of treatment of symptomatic … However, SBRT efficacy and safety data are derived from lower quality studies with variable exclusion … been an abundance of recently published studies, including clinical trials, affirming the safety and efficacy … Efficacy of radiotherapy for painful bone metastases during the last 12 weeks of life: Results from the … A randomized controlled trial to compare the efficacy of bisphosphonates in the management of painful

213. - (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease-future_research.pdf
     July 01, 2016 - In addition, they reported that the “efficacy and safety of long-term immunomodulation versus anti-TNF … (such as disease flare and abscess) are safety outcomes or efficacy outcomes; (g) clearly accounting … Study design: Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: … Study design: Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment … Study design: Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model:

214. Searching for Relevant Studies (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/searching.ppt
     January 01, 2011 - Efficacy and harms searches may be separate. … Efficacy evaluations frequently are limited to RCTs. … Selective publication of antidepressant trials and its influence on apparent efficacy. … This can be important for determining efficacy and harms. … More than one search may be needed (e.g., separately for “efficacy” and “harms”).

215. Fatty-Acids-Cardiovascular-Disease Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_research-protocol.pdf
     April 02, 2015 - The Key Questions The key questions address both issues of efficacy (i.e., causal relationships from … • What is the relative efficacy of different n-3 FAs on CVD outcomes and risk factors? … n-3 FA variables and modifiers: • How does the efficacy or association of n-3 FA in preventing CVD … • How does the efficacy or association of n-3 FA on CVD outcomes and risk factors differ by ratios … • How does the efficacy or association of n-3 FA on CVD outcomes and risk factors differ by source

216. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
     January 01, 2012 - Only one surgical treatment has definitively demonstrated long-term efficacy for morbidly obese patients … While preliminary results are promising, experts opined that further studies evaluating efficacy and … Regardless of the potential treatment efficacy, the EndoBarrier appears to have significant potential … A multicenter, randomized efficacy study of the EndoBarrier gastrointestinal liner for presurgical … Safety and efficacy study of EndoBarrier in subjects with type II diabetes and obesity.

217. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0086_04-01-2009.pdf
     January 01, 2009 - However research on both efficacy and drug-supplement interactions is difficult to come by.

218. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - within 0–4 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … side effects, extensive lag time between start of medication and therapeutic effects, suboptimal efficacy … Depending on DBS treatment efficacy in individuals, its use might allow some patients to use lower … Experts suggested that because of ketamine’s rapid efficacy, this agent may be most useful in patients … Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled

219. Disposition of Comments for Venous Thromboembolism Prophylaxis in Orthopedic Surgery (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
     March 01, 2012 - and Safety Outcomes for RECORD 1-4 Studies Efficacy Outcomes Primary Efficacy Outcome ● DVT, … PE, and VT E-related mortality Other Efficacy Outcomes ● Symptomatic VTE during treatment and … We propose the following rubric: 1, Efficacy; 2, Safety; 3, Cost. … The relative significance of efficacy vs safety is somewhat more difficult to parse. … ; Improved Safety 2) Improved Efficacy; No improvement in Safety 3) No improvement in Efficacy; Improved

220. Topic 0438 Risk stratification and CAD NSD FINAL_SJ-2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0520-131115.pdf
     May 29, 2025 - comparative diagnostic accuracy, diagnostic thinking, and therapeutic and from Nominator: patient outcome efficacy