Results

Total Results: 1,134 records

Showing results for "efficacy".

181. Omega−3 Fatty Acids and Cardiovascular Disease: An Updated Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
     August 01, 2016 - Key Questions The Key Questions address issues of efficacy (i.e., causal relationships from trials) … • What is the relative efficacy of different n-3 FA on CVD outcomes and risk factors? … • How does the efficacy or association of n-3 FA on CVD outcomes and risk factors differ by source … What is the relative efficacy of different n-3 FA on CVD outcomes and risk factors? … • There is low strength of evidence of greater efficacy of marine oils over ALA. 1.3.

182. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
     December 14, 2010 - Comparators: N/A Outcomes: Efficacy and effectiveness outcomes are the same as in KQ1. … For efficacy/effectiveness outcomes, a statistician will extract data. … We will define loss to follow-up as the number of patients excluded from efficacy analyses, expressed … Data Synthesis Our a priori analytic plan is to summarize the evidence for efficacy and effectiveness … For the efficacy and comparative effectiveness analyses, we will focus on studies that report outcomes

183. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - within 0–3 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … FDA has requested additional data supporting efficacy, including:  The ability of Probuphine to provide … The approach enhances collaboration among many existing programs and resources to purportedly boost efficacy … In 2011, Project Lazarus’ founders published preliminary efficacy data from 2009 and 2010. … health 5 systems background acknowledged the preliminary nature of the overdose prevention efficacy

184. Comparative Effectiveness of Medications in Patients with Epilepsy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
     March 01, 2012 - You are correct that there is likely variability between newer agents in terms of efficacy and safety … Our review sought to answer questions about the efficacy of newer antiepileptic medications as compared … Switchback rates are surrogates for either efficacy or tolerability that some content experts felt … (including broad spectrum efficacy--i.e., effective in both partial and generalized onset seizures) … In our report, we evaluated overall withdrawal, withdrawal due to lack of efficacy and withdrawal due

185. Disposition of Comments for Chronic Urinary Retention: Comparative Effectiveness and Harms of Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-urinary-retention_disposition-comments.pdf
     September 15, 2014 - Pessary placement would have been included had we found studies assessing their efficacy or comparative … Cruz F, et al: Efficacy and safety of onabotulinumtoxinA in patients with urinary incontinence due to … This focus of this review was to assess the efficacy and/or comparative effectiveness of treatments … Systematic reviews that assess the efficacy and effectiveness of bladder management interventions for … Efficacy and Safety of Botulinum Toxin A Intradetrusor Injections in Adults with Neurogenic Detrusor

186. 08 Functional Limitations Potential High Impact 2012-12-10 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/08_functional_limitations_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - Experts commenting on this drug generally believe that if efficacy is confirmed in pivotal trials, … These therapies have limited efficacy and are invasive and associated with adverse events, marking … FDA did not cite any clinical safety or efficacy issues or request any additional clinical studies … Experts expressed concerns over limited efficacy and safety studies available for this device. … Efficacy and tolerability of MAP0004, a novel inhaled therapy, in treating acute migraine.

187. Fibromyalgia Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
     January 01, 2015 - What are the efficacy and comparative effectiveness of treatments for fibromyalgia in each of these … Efficacy of an EMG- biofeedback therapy in fibromyalgia patients. … Efficacy of milnacipran in patients with fibromyalgia. J Rheumatol. 2005 Oct;32(10):1975-85. … Differential efficacy of written emotional disclosure for subgroups of fibromyalgia patients. … Efficacy of Raloxifen in treatment of fibromyalgia in menopausal women.

188. Allergy-Seasonal Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_executive.pdf
     July 01, 2013 - Comparison of efficacy and harms findings for four treatment comparisons Comparison Representationa … Efficacy Outcome Harms Outcome 1. … • As described below, reporting of efficacy outcomes in SAR research is currently nonstandard. … The efficacy of nasal antihistamines in the treatment of allergic rhinitis. … Criteria for clinical efficacy--readout and monitoring of clinical studies.

189. Type-2-Diabetes-Medications-Update Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
     December 31, 2013 - A randomized, parallel group, double-blind, multicentre study comparing the efficacy and safety of … Efficacy and safety of alogliptin added to 26 http://www.effectivehealthcare.ahrq … Efficacy and safety of insulin detemir once daily in combination with sitagliptin and metformin: … Efficacy and safety of treatment with sitagliptin or glimepiride in patients with type 2 diabetes … Safety and efficacy of linagliptin as add-on therapy to metformin in patients with type 2 diabetes

190. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-executive-170505.pdf
     May 01, 2017 - Whereas the efficacy of TKR for improving pain and function has been demonstrated, not all patients … For the current report, we excluded studies that used only comparators of unclear efficacy (e.g., HA … The efficacy of a topical gel prepared using Lake Urmia mud in patients with knee osteoarthritis. … [Analgesic efficacy of TENS therapy in patients with gonarthrosis. … Efficacy of lateral heel wedge orthotics for the treatment of patients with knee osteoarthritis.

191. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-3.pdf
     June 01, 2022 - Model-based Meta-analysis to Compare Primary Efficacy-endpoint, Efficacy-time Course, Safety, and Tolerability … Efficacy of tapentadol prolonged release for pre- and post-operative low back pain: a prospective … Acceptability and efficacy of naltrexone for criminal justice-involved individuals with opioid use … Comparative Efficacy of Therapeutics for Chronic Cancer Pain: A Bayesian Network Meta-Analysis. … Safety and efficacy of the unique opioid buprenorphine for the treatment of chronic pain.

192. Attention Deficit Hyperactivity Disorder: Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
     October 01, 2011 - From a design hierarchy perspective, comparative group designs provide stronger evidence for efficacy … Two reports focus on the safety and continued efficacy of the noradrenergic agonist GXR.70,71 Three … Efficacy and safety of immediate­release methylphenidate treatment for preschoolers with ADHD. … Efficacy of parent­child interaction therapy: interim report of a randomized trial with short­term … Efficacy of methylphenidate among preschool children with developmental disabilities and ADHD.

193. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol-amendment.pdf
     January 08, 2025 - OROS-methylphenidate efficacy on specific EPC Protocol Version 21, 3/4/2024 executive … Efficacy of meta-cognitive therapy for adult ADHD. … Efficacy, safety and variability in pharmacotherapy for adults with attention deficit hyperactivity … Efficacy of Cognitive Behavioral Therapy Combined with Pharmacotherapy Versus Pharmacotherapy Alone … A comparison of efficacy between cognitive behavioral therapy (CBT) and CBT combined with medication

194. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
     February 01, 2015 - within 0–3 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … Multiple experts wanted to see additional efficacy data, including evidence of citalopram’s superiority … on these hypotheses, American and European clinical trials are investigating intranasal insulin’s efficacy … Additionally, preliminary data from two trials indicate a possible genetic basis for treatment efficacy … Depending on efficacy from ongoing trials and individual patients’ disease progression, clinicians

195. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
     June 01, 2010 - Unfortunately, given the lack of efficacy (as defined from the regulatory perspective) concluded by … In this setting, the consequence of the lack of efficacy of any therapy that might be utilized is the … studies (Mayer 2005a2° and Mayer 200821) in the evaluation of efficacy in the Draft Report. … The report does not claim that the Stein TBI RCT was powered for efficacy outcomes. … Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage.

196. Cer-242-Radiation-Therapy-Brain-Metastases-Evidence-Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
     June 01, 2021 - Other therapies have been investigated as co-interventions with radiation therapy to either increase efficacy … Outcomes including efficacy, impact on quality of life and neurocognition, and adverse effects are important … information on the optimal technique (e.g. hippocampal avoidance WBRT), dose and fractionation, and efficacy

197. Template for Reports Developed (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-updates_methods.pdf
     July 01, 2011 - ‘No Tx’ (RCTs) Outcome-1 (e.g., efficacy) Sub-population-1 (e.g., males) 5 1.5 (1.1, 1.7)£ … ‘PL’ (RCTs) Outcome-1 (e.g., efficacy) Sub-population-1 (e.g., males) 3 0.9 (0.8, 1.4) N=3 … 0 0.9 (0.8, 1.4) N=3 None No evidence of difference in efficacy between ‘A’ and ‘PL’ in males … ‘B’ (Non- RCTs) µ Outcome-1 (e.g., efficacy) Sub-population-1 (e.g., males) 2 2.3 (1.5, 3.4 … -1 (e.g., males) No evidence of difference in efficacy between ‘A’ and ‘C’ in males KQ may need

198. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
     April 01, 2022 - Model-based Meta-analysis to Compare Primary Efficacy-endpoint, Efficacy-time Course, Safety, and Tolerability … Efficacy of tapentadol prolonged release for pre- and post-operative low back pain: a prospective … Comparative Efficacy of Therapeutics for Chronic Cancer Pain: A Bayesian Network Meta-Analysis. … Safety and efficacy of the unique opioid buprenorphine for the treatment of chronic pain. … Efficacy and safety of morphine hydrochloride in cancer patients with chronic pain.

199. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/management-adhd-adults-protocol.pdf
     June 10, 2024 - Efficacy of meta-cognitive therapy for adult ADHD. … The Efficacy of Computerized Cognitive Training in Adults With ADHD: A Randomized Controlled Trial. … Efficacy, safety and variability in pharmacotherapy for adults with attention deficit hyperactivity … Efficacy of Cognitive Behavioral Therapy Combined with Pharmacotherapy Versus Pharmacotherapy Alone … A comparison of efficacy between cognitive behavioral therapy (CBT) and CBT combined with medication

200. Asthma-Immunotherapy-2010 Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_executive.pdf
     January 01, 2010 - We included 74 references that investigated the efficacy and safety of subcutaneous immunotherapy, … 60 studies that investigated the efficacy and safety of sublingual immunotherapy, and 8 studies that … Efficacy of subcutaneous immunotherapy in the pediatric subpopulation. … Efficacy of sublingual immunotherapy in the pediatric subpopulation. … Discussion For this review of the effectiveness, efficacy, and safety of specific immunotherapy, we