-
effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1506.pdf
June 01, 2015 - within 0–3 years of potential diffusion (e.g., in
phase III trials or for which some preliminary efficacy … in untested
populations and wanted to see more data evaluating long-term efficacy and effect size … To date,
researchers have published intervention efficacy data based on adult patients in Scotland, … Experts thought that available clinical trial data
indicated interactive text-messaging’s efficacy … Efficacy of intranasal naloxone as a needleless
alternative for treatment of opioid overdose in
the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
October 01, 2014 - Check for Qualitative Signals
The authors of the original CER conducted meta-analyses on the efficacy … Efficacy, long-term safety, and tolerability of
ziprasidone in children and adolescents with bipolar … Efficacy, long-term safety, and tolerability of
ziprasidone in children and adolescents with bipolar … SGAs were superior to placebo on the efficacy of SGAs in reducing aggression (-6.49
various measures … The primary efficacy measure was change in PANSS total
score from baseline to day 42.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
July 01, 2012 - prevalence of the
underlying condition or risk is low, or if the treatment options are of marginal efficacy … test to
classify a patient into a
disease/phenotype or
prognosis category
Diagnostic accuracy efficacy … Ability of a test to direct
clinical management
and improve patient
outcomes
Diagnostic thinking efficacy … Therapeutic efficacy
Patient outcome efficacy
Clinical utility
Impact on mortality or morbidity … The efficacy of
diagnostic imaging. Med Decis Making
1991;11(2):88-94.
22.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
June 01, 2015 - However, the experts thought additional clinical studies are needed to compare the efficacy of … ES-4
secukinumab to TNF inhibitors as well as to determine long-term efficacy of secukinumab. … However, the experts thought that
long-term efficacy data are needed to determine secukinumab’s true … Novartis Pharmaceuticals. 16 week efficacy
and 2 year long term safety and efficacy of
secukinumab … Novartis Pharmaceuticals. 16 week efficacy
and 5 year long term efficacy, safety and
tolerability
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
August 01, 2012 - events (AEs) and a lack of improvement in their
symptoms.4 As a result, ongoing evaluations of drug
efficacy … with schizophrenia,
schizophrenia-related psychoses, or bipolar disorder,
what are the comparative efficacy … Tables with a summary of findings for efficacy and safety
are presented below. … The authors reported that the overall efficacy
of the FDA-approved SGAs clozapine, olanzapine, and … Analysis of efficacy and
side effects in CATIE demonstrates drug response subgroups and
potential for
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-preventive-services-executive-summary.pdf
June 01, 2022 - services resulted in
similar rates of repeat IPV, depression, fear of partner, coercive control, self-
efficacy … Low
Self-efficacy Interactive online tools;
computerized encounters;
in-person interviews
followed … 3 RCTs (919) Telehealth is at least as effective as
usual care alternatives for improving
self-efficacy
-
effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
November 01, 2016 - within 0–3 years of potential diffusion (e.g., in
phase III trials or for which some preliminary efficacy … A clinical study to evaluate the safety and
efficacy of elagolix in subjects with moderate to
severe … Study to evaluate the long-term safety
and efficacy of elagolix in subjects with moderate
to severe … A global phase 3 study to evaluate the
safety and efficacy of elagolix in subjects with
moderate … Global study to evaluate the long-term
safety and efficacy of elagolix in subjects with
moderate
-
effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
November 01, 2016 - within 0–3 years of potential diffusion (e.g., in
phase III trials or for which some preliminary efficacy … Study to evaluate the long-term safety
and efficacy of elagolix in subjects with moderate
to severe … A global phase 3 study to evaluate the
safety and efficacy of elagolix in subjects with
moderate … Global study to evaluate the long-term
safety and efficacy of elagolix in subjects with
moderate … A clinical study to evaluate the safety and
efficacy of elagolix in subjects with moderate to
severe
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
May 29, 2025 - $Comparison$of$the$efficacy$
and$safety$profiles$of$two$fixed"dose$combinations$of$antihypertensive$ … $Antihypertensive$efficacy$and$
safety$of$olmesartan$medoxomil$and$ramipril$in$elderly$patients$with … $This$double"blind,$controlled,$randomised$trial$compared$its$antihypertensive$efficacy$and$safety$vs … ''
$
OBJECTIVES:$The$AliSkiren$Study$of$profound$antihypERtensive$efficacy$in$hyperTensIVE$patients … ''
$
OBJECTIVE:$To$assess$the$antihypertensive$efficacy$of$olmesartan$medoxomil$and$ramipril$on$24
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-3-acute-pain.pdf
June 01, 2022 - Efficacy
of routinely used analgesics in management
of pulpal pain postoperatively a clinical
study … Efficacy and safety of two fixed-dose
combinations of tramadol hydrochloride and
diclofenac sodium … Analgesic efficacy of naproxen sodium
versus hydrocodone/acetaminophen in acute
postsurgical dental … The
efficacy of cannabis in reducing back pain: a
systematic review. … Evaluation of the efficacy of liposomal
bupivacaine in total joint arthroplasty.
-
effectivehealthcare.ahrq.gov/products/cardio-dental/research
-
effectivehealthcare.ahrq.gov/products/atypical-antipsychotics-off-label-update/research-protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Only one surgical treatment (gastric bypass surgery) has definitively demonstrated long-term
efficacy … However, experts generally indicated a need for more
trials to determine the safety and efficacy of … However, some
experts expressed concern regarding long-term efficacy and the potential for patients … One expert with a research perspective noted the limited amount of long-term safety and efficacy
data … A prospective,
randomized multicenter study to evaluate the
safety and efficacy of the ReShape Duo
-
effectivehealthcare.ahrq.gov/sites/default/files/interactive_media_epstein_respondent.pdf
January 01, 2009 -
Slide
7:
When
providing
information
is
not
enough…
• Promoting
self-‐efficacy … • Self-‐efficacy
• Capability
• Peer
or
family
support
Source:
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_executive.pdf
September 01, 2011 - A 2006 study on Efficacy and Comparative
Effectiveness of Off-label Use of Atypical
Antipsychotics reviewed … the scientific
evidence on the safety, efficacy, and
effectiveness for off-label uses. … The efficacy results are summarized in Table A below. … The evidence that atypicals have efficacy in treating
symptoms of dementia has increased in the past … There are insufficient data regarding efficacy,
effectiveness, and harms to determine what subset of
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
October 01, 2014 - Depending on DBS efficacy, its use might allow some patients to eliminate or lower their drug;
however … Efficacy and safety of mifepristone for the
treatment of psychotic depression. … Replication of ketamine's antidepressant efficacy
in bipolar depression: a randomized controlled … Antidepressant efficacy of ketamine in treatment-
resistant major depression: a two-site randomized … A study of the
use of IV scopolamine to augment the efficacy of
electroconvulsive therapy (ECT).
-
effectivehealthcare.ahrq.gov/sites/default/files/prostatic-hyperplasia-medications_disposition-comments.pdf
May 26, 2016 - TEP Reviewer
#1
Introduction Page 2, line 2: The reviewer suggests that it is effectiveness, not efficacy … darifenacin, and trospium showed X for
efficacy but low SOE in all trials- I felt like that was missing … (for example, you do say “evidence was insufficient to assess
efficacy or adverse effects of mirabegron … Additionally,
the durability of benefit is uncertain for the new agents that showed similar efficacy … Participant blinding in PDE-5s
may not be successful given their efficacy
with ED (participants could
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
November 27, 2012 - If a
report were to show improve efficacy with a
less convenient therapy that would be a
decision … Other missing papers of note:
Efficacy of biologics in the treatment of moderate to severe psoriasis … Unfortunate to
see the short time frames of the available studies for efficacy and harms. … Several intra-individual half-side comparison studies have addressed the
efficacy of narrow-band UV … Efficacy and safety of infliximab vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
March 01, 2012 - Regarding the definition of "normal," the focus of this report is
comparative efficacy of osteoporosis … We have changed the text to read "To date, the comparative
efficacy of available treatments has not … And in
describing included study designs for efficacy and safety, we
note that we included RCTs and … How does this relate to drug efficacy? … Yet these
drugs are not included in the efficacy section. Delete.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
October 27, 2017 - resulted in reduced stroke and bleeding events when compared
with warfarin, and apixaban showed better efficacy … Diagnostic thinking efficacy
Therapeutic efficacy
Patient outcome efficacy … for
predicting thromboembolic risk and bleeding events (KQ1
and 2):
o Diagnostic accuracy efficacy … o Diagnostic thinking efficacy (defined as how using
diagnostic technologies help or confirm the … diagnosis of the referring provider)
o Therapeutic efficacy (defined as how the intended
treatment