Results

Total Results: 1,134 records

Showing results for "efficacy".

101. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0272_03-06-2008.pdf
     January 01, 2008 - While there is consistent evidence on the efficacy of CPAP and its use as a first-line therapy, no comparative

102. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
     January 01, 2010 - than main health outcomes of interest Often not available for vulnerable populations Generally report efficacy … Finally, RCTs generally address efficacy rather than effectiveness. … Randomized controlled trials (RCTs) are the gold standard for evaluating efficacy. … Most randomized controlled trials (RCTs) are efficacy trials. … Patients who are more susceptible to harms are often underrepresented in efficacy trials.

103. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
     January 01, 2010 - than main health outcomes of interest Often not available for vulnerable populations Generally report efficacy … Finally, RCTs generally address efficacy rather than effectiveness. … Randomized controlled trials (RCTs) are the gold standard for evaluating efficacy. … Most randomized controlled trials (RCTs) are efficacy trials. … Patients who are more susceptible to harms are often underrepresented in efficacy trials.

104. Nppv-Respiratory-Failure Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
     July 01, 2012 - We rated each of the seven items as effectiveness (score = 1) or efficacy (score = 0); scores were … Final efficacy-effectiveness scores were based on the mean of two independent ratings. … For these analyses, we categorized studies as mostly efficacy (score of 0–2), mixed efficacy-effectiveness … Most studies were classified as mixed efficacy-effectiveness studies; only two were classified as … A simple and valid tool distinguished efficacy from effectiveness studies.

105. Gout Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
     March 01, 2016 - • High-strength evidence supports the efficacy of NSAIDs to reduce pain in acute gout. … African-American) do not affect the efficacy of febuxostat or allopurinol. … Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol. … Diabetes and gout: efficacy and safety of febuxostat and allopurinol. … African American patients with gout: efficacy and safety of febuxostat vs allopurinol.

106. Trauma-Interventions-Maltreatment-Child Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_executive.pdf
     April 01, 2013 - Scope and Key Questions This review provides a critical analysis and synthesis of the comparative efficacy … This trial assessed the comparative efficacy of Trauma Focused-Cognitive Behavioral Therapy (TF-CBT) … The efficacy of group treatment in sexually abused girls. … The efficacy of a relational treatment for maltreated children and their families. … Standards of evidence: criteria for efficacy, effectiveness and dissemination.

107. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - Only one surgical treatment (gastric bypass surgery) has definitively demonstrated long-term efficacy … If liraglutide demonstrates safety and long-term efficacy, it could fulfill a large unmet 14 … Experts agreed that lorcaserin’s impact potential depends heavily on the drug’s long- term efficacy … Efficacy comparisons with existing oral drug therapy for obesity do not exist, one research expert … A prospective, randomized multicenter study to evaluate the safety and efficacy of the ReShape Duo

108. Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
     May 01, 2016 - Efficacy studies only measured outcomes at the end of treatment (8 weeks to 6 months) and had no long-term … Pharmacological Interventions Efficacy studies of pharmacological interventions only measured outcomes … Overview of Clinical Research Evidence Table 1: Summary of Key Findings for the Efficacy and Comparative … identified several gaps and limitations in the evidence base: �� A critical gap exists in long-term efficacy … most evident for pharmacological and combination treatments. �� The evidence base for treatment efficacy

109. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
     July 01, 2013 - Only one surgical treatment (gastric bypass surgery) has definitively demonstrated long-term efficacy … If liraglutide demonstrates safety and long-term efficacy, it could fulfill a large unmet need. … Experts agreed that lorcaserin’s impact potential will depend heavily on the drug’s efficacy, with … There is no “efficacy comparison with existing oral drug therapy for obesity,” one research expert … A prospective, randomized multicenter study to evaluate the safety and efficacy of the ReShape Duo

110. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-bone-fracture_research-protocol.pdf
     May 14, 2010 - Evidence-based Practice Center (EPC) completed the first Comparative Effectiveness Review (CER) on the efficacy … However, treatment efficacy depends upon adherence, and although fracture trials that reported data … And c) Does efficacy of monitoring vary among the pharmacotherapies? … Inclusion criteria for effectiveness/efficacy questions: For titles obtained through the searches for … Assessment of Methodological Quality of Individual Studies For studies of efficacy, it is anticipated

111. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
     March 01, 2013 - MTX: No differences in adverse events in efficacy studies. … (Moderate) Biologic DMARDs plus MTX vs. biologic DMARDs: No differences in adverse events in efficacy … MTX: No differences in adverse events in efficacy studies. … (Moderate) Biologic DMARDs plus MTX vs. biologic DMARDs: No differences in adverse events in efficacy … biologic DMARDs: No differences in adverse events in efficacy studies.

112. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
     March 01, 2013 - MTX: No differences in adverse events in efficacy studies. … (Moderate) Biologic DMARDs plus MTX vs. biologic DMARDs: No differences in adverse events in efficacy … MTX: No differences in adverse events in efficacy studies. … (Moderate) Biologic DMARDs plus MTX vs. biologic DMARDs: No differences in adverse events in efficacy … biologic DMARDs: No differences in adverse events in efficacy studies.

113. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - The risk of withdrawing due to lack of efficacy was also significantly higher for newer antiepileptic … Comparative efficacy of combination drug therapy in refractory epilepsy. … Efficacy and safety of innovator versus generic drugs in patients with epilepsy: a systematic review … In patients with epilepsy, what is the comparative effectiveness/efficacy of antiepileptic medications … In patients with epilepsy, what is the comparative effectiveness/efficacy of antiepileptic medications

114. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - The risk of withdrawing due to lack of efficacy was also significantly higher for newer antiepileptic … Comparative efficacy of combination drug therapy in refractory epilepsy. … Efficacy and safety of innovator versus generic drugs in patients with epilepsy: a systematic review … In patients with epilepsy, what is the comparative effectiveness/efficacy of antiepileptic medications … In patients with epilepsy, what is the comparative effectiveness/efficacy of antiepileptic medications

115. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
     December 09, 2009 - stimulation (rTMS), or demonstrated effective psychotherapy (e.g., cognitive therapy [CBT or IPT]) differ in efficacy … How do these non-pharmacologic treatments compare with pharmacological treatments in efficacy or effectiveness … For adults with TRD, do non-pharmacologic interventions differ in their efficacy or effectiveness for … Do non-pharmacologic interventions (single or combination) differ in their efficacy or effectiveness … Specifically, the first two key questions pertain to the efficacy and effectiveness of obtaining (KQ1

116. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - within 0–3 years of potential diffusion (e.g., in phase III trials or for which some preliminary efficacy … Several ES-4 experts expected that the modest demonstrated efficacy and requirement for repeated … Treatments are aimed at symptomatic relief, but questions of safety and efficacy remain. … be moderate, depending on the number of irritable bowel syndrome patients in the practice and the efficacy … Salix's TARGET 3 study examines the safety and efficacy of repeat treatment with rifaximin 550 mg

117. Disposition of Comments Report for Allergen-Specific Immunotherapy for the Treatment of Allergic Rhinoconjunctivitis and/or Asthma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_disposition-comments.pdf
     January 01, 2010 - /III clinical study, of 400+ ragweed-allergic patients with RCS, completely failed to demonstrate efficacy … These secondary measures of clinical efficacy are important outcomes that further define the therapeutic … SLIT data may not accurately address the efficacy of SLIT because tablets or preparations intended … Studies addressing the efficacy of SIT in asthmatics may demonstrate efficacy for mild asthmatics but … The authors do not really tease this issue out (as being separate from efficacy within the context

118. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
     September 01, 2011 - well- being is critical to enable us to assess the overall impact of the disease and to quantify the efficacy … How do the efficacy, effectiveness, safety, and adverse effects of treatment with DMARDs differ among … How do the efficacy, effectiveness, Insufficient Only one study—an RCT of methotrexate versus safety, … NSAIDs—evaluated efficacy by JIA category. … Trials that evaluate the efficacy of treatment should be sufficiently long, with frequent assessment

119. Disposition of Comments for Comparative Effectiveness Review 133 Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
     May 27, 2014 - KQ3 gives more specific guidance regarding components of interventions for which we found efficacy. … Supporting the efficacy implies vagary as to whether there was evidence that it doesn’t work or there … We agree that “support the efficacy” can be vague; we have replaced this with “determine” or other … Or “current evidence is inadequate to determine the efficacy of telemonitoring.” … Also, on this bullet, get rid of the wording ‘support the efficacy’.

120. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: Surveillance Report 3 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
     May 01, 2022 - Efficacy of opioids for chronic pain: a review of the evidence. … Efficacy of cannabinoids in fibromyalgia: A literature review. … Off- label use of cannabinoids efficacy and safety. … Safety and efficacy of medical cannabis in fibromyalgia. … Efficacy of inhaled cannabis on painful diabetic neuropathy.