-
psnet.ahrq.gov/node/49630/psn-pdf
July 01, 2011 - These drugs have few drug–drug interactions, are not subject to variations in diet, and, unlike warfarin … addition, the commentary
does not include information regarding investigational or off-label use of pharmaceutical … products or
medical devices. … Overanticoagulation associated with combined
use of antibacterial drugs and acenocoumarol or phenprocoumon … atrial fibrillation and warfarin initiation: high risk periods
and implications for new antithrombotic drugs
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psnet.ahrq.gov/web-mm/right-place-right-drug-wrong-strength
March 26, 2015 - She was being treated with oral acetaminophen around the clock and nonsteroidal anti-inflammatory drugs … A profiled ADC setup releases only drugs that have been ordered and verified to the cabinet patient profile … by minimizing product and concentration options in the hospital formulary, especially for high-alert drugs … management systems, it is worthwhile to try to minimize the number of available concentrations of high-alert drugs
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psnet.ahrq.gov/sites/default/files/import/webmm.ahrq.gov.101_slideshow.ppt
July 01, 2005 - Warfarin
Warfarin is among the most commonly prescribed drugs
Near the top of list of drugs that lead … cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1307227
Drugs that Decrease Warfarin Metabolism and … cmd=retrieve&db=pubmed&list_uids=15911722&dopt=Abstract]
Drugs that Increase Warfarin Metabolism
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psnet.ahrq.gov/node/49668/psn-pdf
October 01, 2012 - nonmedical use of prescription pain medications.(2) Coincident with the greater
availability of these drugs … Use of
sedating drugs (e.g., antihistamines, benzodiazepines) and/or alcohol use, both associated with … Drugs with opioid agonist effects may cause respiratory depression. … The risk is increased in patients
with pre-existing respiratory compromise and with some abused drugs
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psnet.ahrq.gov/web-mm/medication-reconciliation-victory-after-avoidable-error
April 01, 2015 - updated in 2003 using a literature review and expert consensus.( 8 ) The updated Beers list includes drugs … to be avoided regardless of disease state or condition and a list of drugs to be avoided in patients … Dicyclomine, hyoscyamine, other gastrointestinal antispasmodic drugs High risk of anticholinergic … Discrepancies between in-home interviews and electronic medical records on regularly used drugs
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psnet.ahrq.gov/web-mm/miscalculated-risk
March 01, 2015 - As this case illustrates, oral opioids are high-risk drugs worthy of serious consideration when evaluating … morphine.( 5 ) Hydromorphone, meperidine, and morphine have also been erroneously interchanged, as have drugs … medication errors.( 11 ) CPOE might improve analgesic safety by preventing prescribers from ordering drugs … equianalgesic conversion algorithms could be programmed into CPOE software to help prescribers choose drugs
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psnet.ahrq.gov/node/41951/psn-pdf
September 07, 2016 - psnet.ahrq.gov/issue/examining-increase-drug-shortages
https://psnet.ahrq.gov/issue/shortage-perioperative-drugs-implications-anesthesia-practice-and-patient-safety
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psnet.ahrq.gov/node/44644/psn-pdf
February 14, 2017 - accompanying editorial notes that the FDA is under pressure to
relax restrictions on marketing of drugs
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psnet.ahrq.gov/node/40548/psn-pdf
March 23, 2012 - potentially-inappropriate-medications-defined-stopp-criteria-and-risk-adverse-
drug-events
Many medications, particularly sedatives and other drugs
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psnet.ahrq.gov/issue/high-priority-drug-drug-interactions-use-electronic-health-records
September 01, 2016 - March 4, 2015
Preventability of adverse drug events involving multiple drugs using publicly
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psnet.ahrq.gov/web-mm/direct-oral-anticoagulants-are-high-risk-medications-potentially-complex-dosing
August 21, 2005 - DOAC drugs should not be considered simply as substitutes for warfarin because their mechanism of action … Compared to warfarin, DOAC drugs are not as effective in preventing thrombosis for some conditions. … in patients taking it as compared to patients taking warfarin. 11 In combination with anti-platelet drugs … Titusville, NJ: Janssen Pharmaceuticals Inc.; 2020.
Eikelboom, J, Connoly, S, Bosch, J. … Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2020.
SAVAYSA [Package Insert].
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psnet.ahrq.gov/sites/default/files/import/webmm.ahrq.gov.260_slideshow.ppt
February 01, 2012 - 4 factors:
Informing providers the point of care, allowing them to choose best and most affordable drugs … At Henry Ford Health System, clinical decision support was associated with increased use of generic drugs … with E-prescribing
Experts have recommended all e-prescribing systems use standard nomenclature for drugs
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psnet.ahrq.gov/node/36364/psn-pdf
February 14, 2017 - In this study,
those drugs and digoxin accounted for nearly one-third of ADEs requiring hospitalization
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psnet.ahrq.gov/node/37112/psn-pdf
May 26, 2011 - While the study results are promising, one caveat is that the system was not used for high-risk
drugs
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psnet.ahrq.gov/node/43904/psn-pdf
October 13, 2015 - reducing-unacceptable-missed-doses-pharmacy-assistant-supported-medicine-administration
https://psnet.ahrq.gov/issue/audit-missed-or-delayed-antimicrobial-drugs
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psnet.ahrq.gov/node/39921/psn-pdf
September 01, 2016 - warning abandoned because several patients experienced delays in needed
treatment with one of the drugs
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psnet.ahrq.gov/node/46587/psn-pdf
January 23, 2019 - The most frequently observed medication administration errors included omissions,
administration of drugs
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psnet.ahrq.gov/web-mm/mismanagement-delirium
February 13, 2014 - first step in pharmacological management of delirium is to discontinue or reduce doses of psychoactive drugs … Drugs that could cause or worsen delirium should be discontinued or doses adjusted. … sedative hypnotics, anticholinergics, corticosteroids, polypharmacy, withdrawal of alcohol or other drugs … Renal, hepatic, and thyroid function Cultures of urine, blood, sputum Concentrations of suspected drugs … from delirium Management Actions Drug adjustments Reduce or remove psychoactive drugs
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psnet.ahrq.gov/web-mm/mistaken-dose-naloxone
March 21, 2009 - involved opioids – a 12% increase from 2016. 1 This opioid overdose epidemic is due to use of illicit drugs … , highly potent synthetic opioids, mixing of illicit and prescription opioid or sedative drugs, and misused … Prescription drugs: prescribers: naloxone hydrochloride and other FDA-approved drugs , AB 2760 , 2018
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psnet.ahrq.gov/node/49617/psn-pdf
January 01, 2011 - involvement of pharmacists at the time of
therapeutic decisions is encouraged, particularly when prescribing drugs … participation of pharmacists as active members of physician rounding teams reduces preventable
adverse drugs … key patient safety points specific to prescribing potentially
nephrotoxic and/or renally eliminated drugs