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psnet.ahrq.gov/issue/chemotherapy-drug-shortages-pediatric-oncology-consensus-statement
March 15, 2017 - An ethical framework for allocating scarce life-saving chemotherapy and supportive care drugs … April 26, 2023
Nearly all thirty most frequently used emergency department drugs experienced
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psnet.ahrq.gov/issue/diagnostic-error-result-drug-laboratory-test-interactions
November 21, 2018 - Related Resources From the Same Author(s)
Impact of interactions between drugs … February 6, 2019
Impact of interactions between drugs and laboratory test results on
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psnet.ahrq.gov/issue/impact-drug-shortages-patients-cardiovascular-disease-causes-consequences-and-call-action
October 10, 2012 - November 1, 2023
Nearly all thirty most frequently used emergency department drugs experienced … September 7, 2016
Despite federal legislation, shortages of drugs used in acute care
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psnet.ahrq.gov/issue/association-label-drug-use-and-adverse-drug-events-adult-population
February 03, 2011 - The accompanying editorial notes that the FDA is under pressure to relax restrictions on marketing of drugs
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psnet.ahrq.gov/web-mm/novel-drug-misuse
September 30, 2010 - that the commentary does not include information about or discuss investigational or off-label use of pharmaceutical … products or medical devices. … addition, the commentary does not include information regarding investigational or off-label use of pharmaceutical … products or medical devices. … July 14, 2010
Adverse events associated with sedatives, analgesics, and other drugs that
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psnet.ahrq.gov/web-mm/compare-and-contrast
July 16, 2019 - possible risk factors for CN include older age (with normal kidney function), concomitant use of selected drugs … Physicians should avoid other nephrotoxic drugs if at all possible. … addition, their commentary does not include information regarding investigational or off-label use of pharmaceutical … products or medical devices. … Medications – Stop drugs that may increase contrast nephrotoxicity: diuretics and non-steroidal agents
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psnet.ahrq.gov/node/60611/psn-pdf
June 24, 2020 - DOAC drugs should not
be considered simply as substitutes for warfarin because their mechanism of action … Compared to warfarin, DOAC drugs are not as effective in preventing thrombosis for some conditions. … in patients taking it as compared to
patients taking warfarin.11 In combination with anti-platelet drugs … Titusville, NJ: Janssen Pharmaceuticals Inc.; 2020.
2. Eikelboom, J, Connoly, S, Bosch, J. … Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2020.
22. SAVAYSA [Package Insert].
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psnet.ahrq.gov/node/39519/psn-pdf
June 16, 2019 - ismp-medication-error-report-analysis-44
This report discusses examples of serious medication errors involving "sound-alike" drugs
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psnet.ahrq.gov/issue/serious-adverse-drug-events-reported-food-and-drug-administration-1998-2005
June 07, 2016 - Voluntarily reported adverse drug events increased markedly from 1998-2005, with a small proportion of drugs
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psnet.ahrq.gov/node/38375/psn-pdf
December 01, 2019 - The report for the 2nd quarter
of 2019 focuses on problems related to methotrexate errors, addictive drugs
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psnet.ahrq.gov/perspective/conversation-david-juurlink-md-phd
May 22, 2017 - We are rightly reluctant to use nonsteroidal anti-inflammatory drugs in certain patients. … With the pharmacology of these drugs, it makes a lot of sense that that would be the case. … But they'll perceive it as "These drugs are treating my pain and I need to continue them." … It's paradoxical and it's not widely appreciated, but these drugs can themselves cause pain. … The primary goal of medical practice is to relieve suffering and these drugs do have a role.
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psnet.ahrq.gov/perspective/opioid-overdose-patient-safety-problem
May 01, 2017 - We are rightly reluctant to use nonsteroidal anti-inflammatory drugs in certain patients. … With the pharmacology of these drugs, it makes a lot of sense that that would be the case. … But they'll perceive it as "These drugs are treating my pain and I need to continue them." … It's paradoxical and it's not widely appreciated, but these drugs can themselves cause pain. … The primary goal of medical practice is to relieve suffering and these drugs do have a role.
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psnet.ahrq.gov/issue/medication-errors-new-approaches-prevention
November 18, 2016 - 2014
Multimodal system designed to reduce errors in recording and administration of drugs … 2019
Multimodal system designed to reduce errors in recording and administration of drugs
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psnet.ahrq.gov/issue/ismp-national-vaccine-errors-reporting-program-one-three-vaccine-errors-associated-age
July 27, 2016 - July 8, 2015
Survey suggests possible downward trend in identifying key drugs/drug classes … May 7, 2014
Audit of missed or delayed antimicrobial drugs.
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psnet.ahrq.gov/node/49611/psn-pdf
October 01, 2010 - increase the risk of toxicity include advancing age, cardiac status, and concomitant use of other drugs … administered along with other agents that also affect
cardiac conduction (e.g., type I antiarrhytmic drugs … of the
contribution of pharmacokinetic drug interactions to the toxicity profile of antidepressant drugs … CDC: Antidepressants most prescribed drugs in U.S. CNNhealth.com. July 9, 2007. … Antidepressant drugs and the emergence of suicidal tendencies. Drug
Saf. 1993;8:186-212.
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psnet.ahrq.gov/web-mm/one-ace-too-many
June 21, 2016 - Although ACE inhibitors are generally well tolerated, like most drugs, their most worrisome adverse effects … to occur early in therapy.( 4 ) The front-loading of adverse events, which is characteristic of most drugs … concomitant therapies, and comorbid illnesses, particularly renal disease and diabetes mellitus.( 1,2,5 ) Drugs … Second, RCTs restrict or prohibit the concomitant use of other drugs that can cause hyperkalemia. … Can occur with prophylactic doses (eg, 5000 units BID) Nonsteroidal anti-inflammatory drugs
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psnet.ahrq.gov/web-mm/hazards-loading-doses
December 01, 2003 - doses are larger than maintenance doses and most are administered in a single bolus, although some drugs … digoxin, amiodarone) may require multiple loading doses administered over several hours to days.( 1 ) Drugs … With many drugs, an increase in dose will give you a proportional increase in expected concentration. … associated with loading doses.( 7,8 ) From an organizational perspective, these include identifying drugs … that have the greatest risk of causing harm, limiting the number of drugs on formulary that require
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psnet.ahrq.gov/node/846768/psn-pdf
March 29, 2023 - depressant
medications such as opioids should be administered sparingly, and non-opioid analgesic drugs … should be
used whenever possible.17 Neuromuscular blocking drugs also need to be fully reversed prior … on a sufficiently high carbon dioxide level to
drive respiration.25
Reverse neuromuscular blocking drugs … acceleromyography applied to the adductor pollicis muscle
to confirm full recovery from neuromuscular blocking drugs … Ensure adequate reversal of neuromuscular blocking drugs prior to extubation.
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psnet.ahrq.gov/node/43202/psn-pdf
September 11, 2023 - survey will inform the revision of a high-alert medication list used to raise awareness about certain drugs
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psnet.ahrq.gov/web-mm/cardiac-arrest-woman-uti-case-qt-prolongation
March 27, 2024 - Additionally, the list of drugs that are known to prolong the QTc interval should be readily available … Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs. … Torsades de pointes associated with nonantiarrhythmic drugs and observations on gender and QTc. … Interactions of a series of fluoroquinolone antibacterial drugs with the human cardiac K+ channel HERG