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Showing results for "drugs".

621. Disposition of Comments Report for Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
     January 01, 2014 - Should drugs be administered right before PCI, 6 hours prior, 12 hours prior if possible? … I found the descriptions of the classes of drugs very helpful. … This is already a very large report, and delving further into the background for these drugs is out … UFH given the small number of studies with a head-to- head comparison of those drugs. … However, in KQ 1, all three drugs were compared.

622. CER 217 Management of Infertility Evidence Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
     May 01, 2019 - use of ovulation-induction agents including oral (clomiphene citrate or letrozole) and injected drugs … Use of fertility drugs and risk of ovarian cancer: results from a U.S.-based case-control study. … Risk of ovarian cancer in women treated with ovarian stimulating drugs for infertility. … Effects of fertility drugs on cancers other than breast and gynecologic malignancies. … Long-term relationship of ovulation-stimulating drugs to breast cancer risk.

623. Disposition of Comments Report for Evaluation and Treatment of Tinnitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_disposition-comments.pdf
     August 23, 2013 - Initially, these interventions were grouped together and labeled ‘medical’ because drugs and surgeries … I cannot see any advantage to lumping these drugs together but if you do want to group them, the only … We refer to gabapentin, baclofen, alprazolam, and acamprosate as neurotransmitter drugs and specify … Two of these feature experimental drugs that are not currently commercially available and this may be … Similarly, the grouping of antidepressants were in fact 4 different drugs with differing doses.

624. Disposition of Comments for CER 165 Fecal Incontinence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/fecal-incontinence_disposition-comments.pdf
     March 21, 2016 - For example, the easiest treatments to study (drugs) are not necessarily those that are used most … With diet drugs being 'symptom' and replacing sphincter being 'cure' - the issue would be what does … Stool modifying drugs are listed as BOTH pharmacological treatments and standard care treatments. … We assume that the Reviewer is referring to diet, over the counter drugs, PFMT, education, toileting … offers any advantage over standard care (such as dietary fiber supplementation, stool- modifying drugs

625. Stroke-Atrial-Fibrillation Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
     August 01, 2013 - , Bleeding history or predisposition, Labile international normalized ratio, Elderly [>65 years], Drugs … Despite all the potential advantages of the new drugs demonstrated in the clinical trials when compared … with warfarin, the new drugs still do not have a well-validated and -studied immediate antidote. … The shorter half-life of the novel drugs may help in the management of bleeding episodes in patients … receiving these drugs and should provide comfort that bleeding can be controlled without an antidote

626. Stakeholder Involvement in Improving Comparative Effectiveness Reviews: AHRQ and the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement_research.pdf
     September 01, 2011 - support research with a focus on outcomes, comparative clinical effectiveness, and appropriateness of pharmaceuticals … “Treating Type 2 Diabetes, The Oral Diabetes Drugs, comparing Effectiveness, Safety, and Price.” … Consumer Reports Best Buy Drugs. Yonkers, NY: Consumers Union; 2006. 8.

627. Dia 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
     January 01, 2011 - Dia 1 1 Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis (MCDA) and Conjoint Analysis (CA) Maarten J. IJzerman, PhD Professor and chair, department Health Technology & Services Research m.j.ijzerman@utwente.nl Multiple endpoints in …

628. AHRQ's Evidence-based Practice Center Division Annual Report 2019: Solving the Puzzle for Evidence-Based Decision Making (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2019.pdf
     January 01, 2019 - AHRQ's Evidence-based Practice Center Division Annual Report 2019: Solving the Puzzle for Evidence-Based Decision Making AHRQ’s Evidence-based Practice Center Divison Annual Report 2019 Solving the Puzzle for Evidence-Based Decision Making e Evidence-based Practice Center Program 2019 Year in Review EPC Missi…

629. Hypertension-Pulmonary-Arterial Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
     April 01, 2013 - These new data may clarify any effect on mortality and gauge the comparative effectiveness of these drugs … Additionally, combination drug therapy (using multiple drugs with different mechanisms of action) is … In order to 5 optimize PAH care, newer information regarding the latest drugs and combination therapies … compared a single drug (monotherapy) with placebo or standard therapy and included the following drugs … Drugs did not significantly differ in their odds of causing dizziness or diarrhea.

630. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
     May 07, 2010 - an ACEI versus a renin inhibitor, or an ARB versus a renin inhibitor (see Tables 1-3 for included drugs

631. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
     May 22, 2012 - Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation … Catheter ablation versus antiarrhythmic drugs for atrial fibrillation: the A4 study. … nebivolol, timolol) • Calcium channel blockers (verapamil, diltiazem) Clarification that these drugs … nebivolol, timolol) • Calcium channel blockers (verapamil, diltiazem) Clarification that these listed drugs … cardioversion and patient- enabled cardioversion using an ICD • Studies investigating use of antiarrhythmic drugs

632. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline_executive.pdf
     March 01, 2017 - If inflammation is part of the disease process, anti-inflammatory drugs may be effective. … Nonsteroidal Anti- Inflammatory Drugs (NSAIDs) • No evidence was available for the effect of low-dose … Antidementia Treatments • Low-strength evidence shows AChEI antidementia drugs did not reduce the incidence … instrumental activities of daily living; MCI=mild cognitive impairment; NSAIDs=nonsteroidal anti-inflammatory drugs

633. High-Cholestorol-Medicines-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_executive.pdf
     February 01, 2014 - result in an increase in side effects, as patients may experience the side effects common to both drugs … Excluded studies of drugs approved only for the treatment of homozygous FH. … Excluded studies of drugs not approved by the FDA or investigational drugs.

634. Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-research-protocol.pdf
     April 11, 2018 - considerations for AECOPD include short- acting/long-acting inhaled bronchodilators, anti-inflammatory drugs … in patients with advanced COPD suffering from an episode of AECOPD is unclear, especially as these drugs … mechanical ventilations • Complementary and alternative medicine interventions • Investigational drugs … and drugs that are only available outside of the U.S

635. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_executive.pdf
     March 01, 2017 - If inflammation is part of the disease process, anti-inflammatory drugs may be effective. … Nonsteroidal Anti- Inflammatory Drugs (NSAIDs) • No evidence was available for the effect of low-dose … Antidementia Treatments • Low-strength evidence shows AChEI antidementia drugs did not reduce the incidence … instrumental activities of daily living; MCI=mild cognitive impairment; NSAIDs=nonsteroidal anti-inflammatory drugs

636. Disposition of Comments for Diagnostic Accuracy of Screening and Treatment of Post-Acute Coronary Syndrome Depression (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-200-comments-post-acs.pdf
     November 14, 2017 - It is important that this list should not be interpreted as an endorsement of any of these drugs so … this point should be made the first time these drugs are mentioned. … The authors make it clear later in this report that the safety of the majority of these drugs has not … In both COPES and CODIACS, the study psychiatrist prescribed the drugs if the patient preferred an

637. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
     September 01, 2011 - $3,355 per employee during a 3-year observation period—approximately 65 percent related to prescription drugs … .1 At the same time, it is well recognized that some drugs used to treat GERD (such as proton pump inhibitors … Among them are the publication of approximately 3,000 new studies; the introduction of novel drugs; the … The large disease burden, economic impact, and market potential for new drugs and devices explain the

638. Disposition of Comments for Chronic Urinary Retention: Comparative Effectiveness and Harms of Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-urinary-retention_disposition-comments.pdf
     September 15, 2014 - Drugs. 2013:1-12. … , 3 treatment strategies are proposed (surgical, catheters, and drugs). … I remain unclear if these 3 treatments were analyzed for all etiologies - the role of drugs for BPH … However we found no studies of drugs used in treating CUR in men with BPH and no studies of treating

639. uterine-fibroids-protocol-160301 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
     March 01, 2016 -  bleeding;;  In  vitro   fertilization;;  Precocious  puberty;;  Prostate  cancer   AstraZeneca   Pharmaceuticals … indications:     Endometrial  hyperplasia;;  Endometriosis;;   Menopausal  symptom   Bayer  Healthcare   Pharmaceuticals

640. Crosscutting-Horizon-Scan-High-Impact-1312 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … It differentiated 100% of multiple drugs and doses taken simultaneously by type and by dose.