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  1. effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … It differentiated 100% of multiple drugs and doses taken simultaneously by type and by dose.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
    May 07, 2010 - an ACEI versus a renin inhibitor, or an ARB versus a renin inhibitor (see Tables 1-3 for included drugs
  3. effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine/research
  4. Topic-Brief3-Sud (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief3-SUD.pdf
    April 01, 2021 - buprenorphine/naloxone in pain, function, side effects, or use of unprescribed opioids, cocaine, or other drugs … involves shifting “waves” of overdose deaths associated with heroin, synthetic opioids, and prescription drugs
  5. Topic-Brief3-Sud (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief3-SUD.pdf
    April 01, 2021 - buprenorphine/naloxone in pain, function, side effects, or use of unprescribed opioids, cocaine, or other drugs … involves shifting “waves” of overdose deaths associated with heroin, synthetic opioids, and prescription drugs
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-1.pdf
    June 01, 2022 - Results from included studies: KQ 2. nonsteroidal anti-inflammatory drugs ............ … Rimegepant 75 mg is more effective for migraine than nonsteroidal anti-inflammatory drugs: post hoc … Biohaven Pharmaceuticals I. … Biohaven Pharmaceuticals I. … CNS Drugs. 2020 Oct;34(10):1015-24. doi: 10.1007/s40263-020- 00753-1. PMID: 32857291.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/lysosomal-storage-diseases-therapies_research-protocol.pdf
    November 15, 2012 - The ERT manufacturers’ websites will be searched to inform Guiding Questions 1 and 2: Biomarin Pharmaceuticals … Emerging drugs for lysosomal storage diseases. Expert Opin Emerg Drugs 2010 Sep;15(3):495-507. … Inc (March 2010) Zavesca® (miglustat), Actelion Pharmaceuticals, FDA approved in Aug 2003 for adult
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
    April 01, 2022 - Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and … Oral nonsteroidal anti-inflammatory drugs (NSAIDs) for cancer pain in adults. … Drugs R D. 2019 Sep;19(3):247-54. doi:10.1007/s40268-019-0276-x. PMID: 31177479. … Acupuncture combined with opioid drugs on moderate and severe cancer pain: a randomized controlled … Drugs. 2020 Oct;80(15):1563-76. doi:10.1007/s40265- 020-01368-y. PMID: 32737739.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
    January 01, 2009 - especially true in diseases that afflict patients with lower compliance rates such as abusers of alcohol and drugs … evaluating magnesium as a treatment for acute myocardial infarction that were conducted before thrombolytic drugs … , antiplatelet drugs, ß-blockers, and primary percutaneous coronary intervention (PCI) were used Only … as an outcome measure Trials comparing cyclooxygenase-2 inhibitors and nonsteroidal antiinflammatory drugs
  10. effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
    January 01, 2009 - especially true in diseases that afflict patients with lower compliance rates such as abusers of alcohol and drugs … evaluating magnesium as a treatment for acute myocardial infarction that were conducted before thrombolytic drugs … , antiplatelet drugs, ß-blockers, and primary percutaneous coronary intervention (PCI) were used Only … an outcome measure Trials comparing cyclooxygenase-2 inhibitors and nonsteroidal antiinflammatory drugs
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
    January 30, 2012 -  Aspirin + dipyridamole (Aggrenox®)  Dipyridamole (Persantine®)  Combinations of antiplatelet drugs … o Aspirin + dipyridamole (Aggrenox®) o Dipyridamole (Persantine®) o Combinations of antiplatelet drugs … abnormal renal/liver function, stroke, bleeding history or predisposition, labile INR, elderly (>65), drugs … abnormal renal/liver function, stroke, bleeding history or predisposition, labile INR, elderly (>65), drugs
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
    April 01, 2010 - walking devices, had slower measured gait velocities, and used more nonsteroidal anti-inflammatory drugs … outcomes of treatments for knee OA.11 Treatment options include pain relievers, anti- inflammatory drugs … Studies examining the marginal effects of drugs combined with physical therapy will be excluded. … Title 21—Food and Drugs.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-203-adhd-disposition-comments.pdf
    January 01, 2018 - Public Reviewer #4 (Manisha Madhoo, Shire Pharmaceuticals) (Previous row continued) Methods • … CNS Drugs. 2013 Dec;27(12):1081-92. … Public Reviewer #4 (Manisha Madhoo, Shire Pharmaceuticals) Methods Lastly, the authors may want … TEP Reviewer #2 Discussion/ Conclusion [conclusion that for ADHD treatment, FDA-approved drugs most … Yet the conclusions make clear recommendation that "For ADHD treatment, FDA-approved drugs are most
  14. Ced-Appendix-3 (xls file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
    June 24, 2022 - National Institute for Health and Care Excellence (NICE) Specification for Cancer Drugs Fund data collection … www.nice.org.uk/Media/Default/About/what-we-do/NICE-guidance/NICE-technology-appraisal-guidance/cancer-drugs-fund
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
    March 01, 2014 - underreporting side effects and adverse events could limit the assessment of effectiveness of these drugs … studies focusing on the adult population, many of the drug treatment trials we identified included drugs … Finally, we grouped antitussive and protussive drugs into subsets that sometimes included pharmacologically … diverse agents or separate drugs with certain similarities. … Reminder for Parents: Do Not Give Infants Cough and Cold Products Designed for Older Children.www.fda. gov/Drugs
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_consumer.pdf
    August 01, 2015 - � Chemotherapy: Certain drugs are used to kill cancer cells.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
    October 27, 2017 - /liver function, S=stroke, B=bleeding history or predisposition, L=labile INR, E=elderly (> 65), D=drugs … warfarin, with a clear benefit in reducing the occurrence of intracranial hemorrhage. 20-23 These drugs … With the availability of these drugs for clinical use, additional knowledge is needed to help inform … Treatment Description to better understand the relative risks and benefits of these drugs … abnormal renal/liver function, stroke, bleeding history or predisposition, labile INR, elderly (> 65), drugs
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
    November 01, 2012 - injection drug users.16-22 About 60 percent of new infections occur in individuals who report injecting drugs … partners, unprotected sex, and/or sex with a person infected with HCV infection or using injection drugs … Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health
  19. CERs Report cover (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
    September 01, 2010 - and support research on the comparative outcomes, clinical effectiveness, and appropriateness of pharmaceuticalsDrugs based on a person's genetics 37.5% (3) 50.0% (4) 12.5% (1) Q12. … Gene-based drugs 54.5% (6) 9.1% (1) 36.4% (4) Q12. … Drugs that target specific molecular cancer pathways 62.5% (5) 37.5% (3) 0 (0) Q13. … Randomized controlled trials I Drug development 224 Molecular targeted drugs specific
  20. effectivehealthcare.ahrq.gov/sites/default/files/tnd-0855-170515.pdf
    April 28, 2017 - mHealth for Diabetes i Results of Topic Selection Process & Next Steps The nominator, a managed care pharmacist, is interested in a new systematic review evaluating the effectiveness of mobile health (mHealth) technologies for diabetes. This topic met the Effective Health Care Program selection crit…

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