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effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
November 02, 2019 - Evidence-based Practice Center Systematic Review Protocol: Therapies for Clinically Localized Prostate Cancer
Evidence-based Practice Center Systematic Review Protocol
Project Title: Therapies for Clinically Localized Prostate Cancer
Initial Publication Date: September 12, 2019
Amendment Date: November 2,…
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effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … at Point of This Intervention
Patients with OA are often prescribed nonsteroidal anti-inflammatory drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - How about treatment duration in these
drugs? … We have commented on the imprecision for
several drugs due to small samples, and have
run an adjusted … We had mentioned the limited precision from
several drugs. … Public Comment
(Cynthia Russo,
Janssen
Pharmaceuticals,
Inc.) … Public Comment
(Cynthia Russo,
Janssen
Pharmaceuticals,
Inc.)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - How about treatment duration in these
drugs? … We have commented on the imprecision for
several drugs due to small samples, and have
run an adjusted … We had mentioned the limited precision from
several drugs. … Public Comment
(Cynthia Russo,
Janssen
Pharmaceuticals,
Inc.) … Public Comment
(Cynthia Russo,
Janssen
Pharmaceuticals,
Inc.)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - Conclusions
Nonopioid drugs (mainly serotonin-norepinephrine reuptake inhibitor [SNRI]
antidepressants … , pregabalin/gabapentin, and nonsteroidal anti-inflammatory drugs [NSAIDs])
resulted in small to moderate … patients with
specific types of noncancer chronic pain in the short term, with few differences between drugs … Interventions
• Oral pharmacologic agents: nonsteroidal anti-inflammatory drugs, acetaminophen,
muscle … events, cardiovascular events, and liver or kidney-related harms for non-
steroidal anti-inflammatory drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
January 30, 2013 - Additionally, combination drug therapy (using multiple drugs with different mechanisms of
action) is … www.effectivehealthcare.ahrq.gov
Published online: January 30, 2013 4
information regarding the latest drugs … 10, 20, 30,
60, 90 mg
Varies Oral Approved
Afeditab CR Nifedipine
Watson
Pharmaceuticals … 30, 60 mg Varies Oral Approved
Nifediac Nifedipine
Teva
Pharmaceuticals
30, 60, 90
mg … 120, 180,
240 mg
Varies Oral Off-Label use
Diltia Diltiazem Watson
Pharmaceuticals
120, 180
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
August 01, 2020 - for the same drug, while Table 5b summarizes retention findings for XR and daily formulations
for drugs … vulnerability assessment
for rapid dissemination of HIV or HCV
infections among persons who inject drugs … KQ3: Not reported
Fair
Rosenthal,
201634
RCT
USA
Braeburn
Pharmaceuticals
177
Age … Medications Timing & Outcome Interventions Results Quality
Rating
Lofwall, 201835
RCT
USA
Braeburn
Pharmaceuticals
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
April 22, 2013 - Further, adverse effects of antipsychotic drugs
have been thoroughly summarized in existing
systematic … We have revised the document to emphasize
the specific drugs evaluated within classes,
paying particular … name amantadine
We have revised the key points, results, and
SOE table to emphasize the specific drugs … We also reviewed the document to ensure
consistency in how drugs were classified. … We
acknowledge that some drugs are not readily
classified or could be classified in more than
one
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - crisis.10
A recent series of related systematic reviews found that opioids,11 several nonopioid drugs … substances; co-use of kratom or other plant-
based substances and opioids
All KQs: Co-use of other drugs … • Co-use of other interventions for pain: opioids, nonopioids (e.g. nonsteroidal anti-
inflammatory drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/women-hiv_research-protocol.pdf
March 01, 2016 - rates of substance abuse compared
to younger women, they may be more vulnerable to the effects of drugs … depression, PTSD,
bipolar, schizophrenia), addiction and substance abuse (heroin, cocaine, prescription
drugs … , alcohol, smoking, “party” drugs such as MDMA [Ecstasy], Flunitrazepam
[Rohypnol], Ketamine), musculoskeletal
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2019.pdf
January 01, 2019 - AHRQ's Evidence-based Practice Center Division Annual Report 2019: Solving the Puzzle for Evidence-Based Decision Making
AHRQ’s Evidence-based
Practice Center Divison
Annual Report 2019
Solving the Puzzle for Evidence-Based
Decision Making
e
Evidence-based Practice Center Program 2019 Year in Review
EPC Missi…
-
effectivehealthcare.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
January 01, 2011 - Dia 1
1
Integrating stakeholder preferences in
comparative effectiveness research
using multi-criteria decision analysis
(MCDA) and Conjoint Analysis (CA)
Maarten J. IJzerman, PhD
Professor and chair, department Health Technology &
Services Research
m.j.ijzerman@utwente.nl
Multiple endpoints in …
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/monitoring-programs-protocol.pdf
January 01, 2024 - effective are patient safety practices (PSPs) for identifying and monitoring
critical supplies and drugs … and
Economic Security (CARES) Act, established in 2020, which required manufacturers of
certain drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
August 01, 2012 - vs. risperidone No significant difference for economic independence (1 RCT) or attitude
regarding drugs … the pooled results may not have
sufficient power to detect equivalence or noninferiority
between drugs … assessed across studies precluded firm conclusions
regarding the overall effectiveness of individual drugs … Second-generation versus first-
generation antipsychotic drugs for schizophrenia: a meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1306.pdf
June 01, 2013 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … In the health care sector, horizon
scanning pertains to identifying new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … at Point of This Intervention
Patients with OA are often prescribed nonsteroidal anti-inflammatory drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-framework-for-conceptualizing-evidence-needs_0.pdf
December 01, 2017 - Decisions and questions for which health systems seek evidence
• Technology (e.g., drugs, devices, products … and use of evidence in health systems focuses on
the acquisition of health care technology (i.e., drugs … required
evidence.18, 19 In one study, the most common technologies reviewed by HTA programs were
drugs … 19% Policy
18% Non-drug, non-
device intervention 14%
Devices
12% Test, scales, risk
factors
8% Drugs … Penn CEP
FY2006-
2016
58% Rapid
Review (2)
33% Clinical
departments
17% CMO
21% Drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - medication (n=2)
Sedation (n=4)
Constipation (n=4)
Headaches (n=3)
Nausea/vomiting (n=2)
Craving for old drugs … without previous related drug use (including tramadol, Panadol, and Non-Steroidal Anti-Inflammatory Drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/selection-of-data-sources-chapter-8.pptx
January 01, 2013 - The NDC is a unique, 10-digit, 3-segment number that is a standard product identifier for human drugs … Claims submitted to insurance companies for payment for drugs are submitted with the NDC number and information … Risk of death associated with the use of conventional versus atypical antipsychotic drugs among elderly
-
effectivehealthcare.ahrq.gov/sites/default/files/exposure-definition-and-measurement_chapter-4.pptx
January 01, 2013 - exposures of interest are these two treatments, but it is also important to measure exposure to other drugs … such as aspirin or nonsteroidal anti-inflammatory drugs, which could increase the risk of GI bleeds … accurate than the recall of the use of medications (previous use of nonsteroidal anti-inflammatory drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - We searched Drugs@FDA for Medical/
Clinical and Statistical review documents containing harm
data for … Results are presented in terms of a placebo referent,
to rank the drugs based on a common comparator … SGAs Versus SGAs: Comparison of Different Drugs
Sixteen (5 long-term) and 37 (13 long-term) studies … Consensus
development conference on antipsychotic drugs and obesity and
diabetes. … Pediatr
Drugs. 2016;18: 319-328. PMID: 27278054.
38. Yoon Y, Wink LK, Pedapati EV, et al.