-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
August 01, 2012 - vs. risperidone No significant difference for economic independence (1 RCT) or attitude
regarding drugs … the pooled results may not have
sufficient power to detect equivalence or noninferiority
between drugs … assessed across studies precluded firm conclusions
regarding the overall effectiveness of individual drugs … Second-generation versus first-
generation antipsychotic drugs for schizophrenia: a meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
January 01, 2009 - especially true in diseases that afflict patients with lower compliance rates such as abusers of alcohol and drugs … evaluating magnesium as a treatment for acute myocardial infarction that were conducted before thrombolytic drugs … , antiplatelet drugs, ß-blockers, and primary percutaneous coronary intervention (PCI) were used
Only … an outcome measure
Trials comparing cyclooxygenase-2 inhibitors and nonsteroidal antiinflammatory drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - Aspirin + dipyridamole (Aggrenox®)
Dipyridamole (Persantine®)
Combinations of antiplatelet drugs … o Aspirin + dipyridamole (Aggrenox®)
o Dipyridamole (Persantine®)
o Combinations of antiplatelet drugs … abnormal renal/liver function, stroke, bleeding history or predisposition, labile INR, elderly (>65), drugs … abnormal renal/liver function, stroke, bleeding history or
predisposition, labile INR, elderly (>65), drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
April 01, 2010 - walking devices, had slower measured gait velocities, and used
more nonsteroidal anti-inflammatory drugs … outcomes of treatments for knee OA.11 Treatment options include pain relievers, anti-
inflammatory drugs … Studies examining the marginal effects of drugs
combined with physical therapy will be excluded. … Title 21—Food
and Drugs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
January 30, 2013 - Additionally, combination drug therapy (using multiple drugs with different mechanisms of
action) is … www.effectivehealthcare.ahrq.gov
Published online: January 30, 2013 4
information regarding the latest drugs … 10, 20, 30,
60, 90 mg
Varies Oral Approved
Afeditab CR Nifedipine
Watson
Pharmaceuticals … 30, 60 mg Varies Oral Approved
Nifediac Nifedipine
Teva
Pharmaceuticals
30, 60, 90
mg … 120, 180,
240 mg
Varies Oral Off-Label use
Diltia Diltiazem Watson
Pharmaceuticals
120, 180
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1406.pdf
June 01, 2014 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … at Point of This Intervention
Patients with OA are often prescribed nonsteroidal anti-inflammatory drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
June 01, 2011 - Currently, three classes of drugs that interact
with this system are used to inhibit the effects of
angiotensin … (2) Relative persistence with drug therapy across the
different classes of drugs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/emt-naloxon_research-protocol.pdf
November 29, 2016 - race, type of opioid involved in
overdose, dose of opioid involved in overdose, presence of other drugs … race, type of opioid involved in
overdose, dose of opioid involved in overdose, presence of other drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-3-acute-pain.pdf
June 01, 2022 - Opioid therapy versus nonopioid pharmacologic therapy (acetaminophen, non-steroidal
anti-inflammatory drugs … CNS Drugs.
2021;35(1):105-20. doi: 10.1007/s40263-
020-00777-7. PMID: 33428176. … The impact of nonsteroidal anti-
inflammatory drugs on older adult trauma
patients with hip fractures … The treatment
of topical drugs for postherpetic neuralgia: a
network meta-analysis. … Non-steroidal anti-
inflammatory drugs for acute low back pain.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
April 01, 2020 - action of opioids used (e.g., pure
opioid agonists, partial opioid agonists such
as buprenorphine, or drugs … action of opioids used
(e.g., pure opioid agonists, partial opioid
agonists such as buprenorphine, or drugs … function; there were also no differences in
likelihood of a positive urine for opioids, cocaine, or other drugs … https://www.fda.gov/drugs/drug-safety-and-availability/
fda-identifies-harm-reported-sudden-discontinuation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
April 01, 2022 - Effectiveness and safety of non-steroidal
anti-inflammatory drugs and opioid
treatment for knee and … Oral
nonsteroidal anti-inflammatory drugs
(NSAIDs) for cancer pain in adults. … Drugs R
D. 2019 Sep;19(3):247-54.
doi:10.1007/s40268-019-0276-x. PMID:
31177479. … Acupuncture
combined with opioid drugs on moderate
and severe cancer pain: a randomized
controlled … Drugs. 2020
Oct;80(15):1563-76. doi:10.1007/s40265-
020-01368-y. PMID: 32737739.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
March 01, 2014 - underreporting side effects and adverse events could
limit the assessment of effectiveness of these drugs … studies focusing on the adult population, many
of the drug treatment trials we identified included drugs … Finally, we
grouped antitussive and protussive drugs into subsets that
sometimes included pharmacologically … diverse agents or
separate drugs with certain similarities. … Reminder for Parents: Do Not Give Infants
Cough and Cold Products Designed for Older Children.www.fda.
gov/Drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-2.xlsx
September 30, 2015 - medication (n=2)
Sedation (n=4)
Constipation (n=4)
Headaches (n=3)
Nausea/vomiting (n=2)
Craving for old drugs … without previous related drug use (including tramadol, Panadol, and Non-Steroidal Anti-Inflammatory Drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_1-user-guide-to-ocer_130129.pdf
August 13, 2012 - Coverage Which bisphosphonate drugs should be included on a drug formulary? … management What should a health plan do to minimize the risks associated with use of
bisphosphonate drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
April 01, 2021 - health disorders and their healthcare providers is how to balance benefits and harms of
psychotropic drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
October 27, 2017 - /liver function, S=stroke, B=bleeding history or predisposition,
L=labile INR, E=elderly (> 65), D=drugs … warfarin, with a clear benefit
in reducing the occurrence of intracranial hemorrhage.
20-23
These
drugs … With the availability of these drugs for clinical use,
additional knowledge is needed to help inform … Treatment Description
to better understand the relative risks and benefits of these drugs … abnormal renal/liver function, stroke, bleeding history or
predisposition, labile INR, elderly (> 65), drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
December 19, 2018 - action of opioids used (e.g., pure
opioid agonists, partial opioid agonists such as buprenorphine or drugs … there differences between pure opioid agonists and partial opioid agonists
such as buprenorphine or drugs … or
intramuscular
administration of
opioids
Nonopioid
therapies
(pharmacologic
[antiepileptic drugs … ,
benzodiazepines,
nonsteroidal
antiinflammatory
drugs, skeletal
muscle relaxants,
serotonin
norepinephrine
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-use-disorder_research-protocol.pdf
February 24, 2016 - approximately 1.9 million Americans 12
years or older were estimated to have OUD due to prescription drugs … socioeconomically disadvantaged settings with
limited access to care.11,12 Compared with OUD due to prescription drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
May 01, 2014 - anxiolytics,
antidepressants, antivirals, beta-blockers, immune modulators, non-steroidal anti-
inflammatory drugs … unique identifier] (36939)
18 16 or 17 (140490)
19 exp drug therapy/ (1112200)
20 exp drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
September 01, 2010 - and support research on the comparative
outcomes, clinical effectiveness, and appropriateness of pharmaceuticals … Drugs based on a person's genetics
37.5%
(3)
50.0%
(4)
12.5%
(1)
Q12. … Gene-based drugs
54.5%
(6)
9.1%
(1)
36.4%
(4)
Q12. … Drugs that target specific molecular cancer
pathways
62.5%
(5)
37.5%
(3)
0
(0)
Q13. … Randomized controlled trials I
Drug development 224
Molecular targeted
drugs specific