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Showing results for "drugs".

401. S116 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s116.pdf
     October 01, 2007 - Helen Mogun, MS, and Sebastian Schneeweiss, MD, ScD Background: Postmarketing studies of prescription drugs … Violations of the exclusion restriction can occur if physicians who more frequently use the older drugs … Risk of death associated with the use of conventional versus atypical antipsychotic drugs among elderly

402. Fecal-Incontinence Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
     November 30, 2014 - In general, initial FI treatments tend to be conservative (diet, drugs, exercises, etc.) and become … do not achieve the desired level of continence may be augmented by dietary changes, exercises, or drugs … Sphincter function enhancers (topical phenylepinephrine gel, sodium valproate)  Other bowel-affecting drugs … English language RCTs and observational studies published from 1980 forward (to include early studies of drugs … We will also review Scientific Information Packets sent by manufacturers for relevant pharmaceuticals

403. Appendix A. Long COVID Models of Care – Grey literature sources (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-covid-appendix-a.pdf
     December 01, 2022 - Physical Medicine & Rehabilitation; ACC = American College of Cardiology; CADTH = Canadian Agency for Drugs

404. Systematic Review on Treatments for Acute Pain: Surveillance Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-2-acute-pain.pdf
     May 01, 2022 - Opioid therapy versus nonopioid pharmacologic therapy (acetaminophen, non-steroidal anti-inflammatory drugs … CNS Drugs. 2021;35(1):105-20. doi: 10.1007/s40263- 020-00777-7. PMID: 33428176. … The impact of nonsteroidal anti- inflammatory drugs on older adult trauma patients with hip fractures … The treatment of topical drugs for postherpetic neuralgia: a network meta-analysis. … Non-steroidal anti- inflammatory drugs for acute low back pain.

405. Disposition of Comments CER 214 Stroke Prevention in Patients With Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
     October 30, 2019 - First, the 2 study drugs have very different PK and PD properties, such that data scopes of greater … Secondly, based on the mechanism of action of the study drugs (anticoagulation) and the persistence … We felt that allowing the reader to see how the individual drugs performed in the same study was … When NOACs were initially being studied, there was an emphasis on comparing these drugs to warfarin … As noted on page 124 the document ” We also synthesized the findings for individual drugs.

406. Management of Acute Diverticulitis Additional Information for Topic Nomination (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diverticulitis-nomination-extra.pdf
     October 08, 2025 - Management of Acute Diverticulitis Additional Information for Topic Nomination Table 1. Key Questions and PICOTS KQ1: Antibiotics KQ1: Antibiotics vs. No Antibiotics KQ2: Diagnostic imaging KQ3: Follow-up colonoscopy KQ4: Surgical and interventional management KQ5: Prevention of recurrence Populat…

407. Mental-Illness-Heart Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
     April 01, 2013 - Adverse effects of psychotropic drugs (notably second-generation antipsychotics) also may contribute … The drug classes in our review sometimes included drugs with diverse mechanisms of action. … datasets No studies comparing optimized antipsychotic management (e.g., start with or switch to drugs … RCTs may be particularly useful for interventions specifically tailored for SMI populations and for drugs … Metabolic screening after the American Diabetes Association's consensus statement on antipsychotic drugs

408. Acute Treatment for Episodic Migraine: Surveillance Report 2 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
     June 01, 2022 - support the conclusions from the original report that triptans and nonsteroidal anti- inflammatory drugs … Results from included studies: KQ 2, nonsteroidal anti-inflammatory drugs ............ … versus: (1) nonopioid pharmacologic therapy (e.g., acetaminophen, nonsteroidal anti-inflammatory drugs … Abbreviations: ED = emergency department; KQ = Key Question; NSAID = nonsteroidal anti-inflammatory drugs … Results from included studies: KQ 2, nonsteroidal anti-inflammatory drugs Author, Year, Study Design

409. S77 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
     October 01, 2007 - number of prescriptions filled for 30-day periods, we are unable to calculate the actual use of generic drugs … a sliding-scale basis for this group, and because copayments are tied to the cost of their specific drugs

410. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
     June 01, 2017 - The modalities can be used alone or in combination, at variable doses (of drugs) or regimens (of mechanical … history of abnormal surgical bleeding or bleeding disorder, prior medications (e.g., antiplatelet drugs … Studies evaluated the following thromboprophylaxis classes (and combinations thereof): antiplatelet drugs … Among four RCTs of low versus high dose FXaI, studies favored higher dose FXaI (multiple drugs, mostly … In particular, there are sparse RCTs or NRCSs that evaluated antiplatelet drugs (e.g., aspirin), VKA

411. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
     June 01, 2017 - The modalities can be used alone or in combination, at variable doses (of drugs) or regimens (of mechanical … history of abnormal surgical bleeding or bleeding disorder, prior medications (e.g., antiplatelet drugs … Studies evaluated the following thromboprophylaxis classes (and combinations thereof): antiplatelet drugs … Among four RCTs of low versus high dose FXaI, studies favored higher dose FXaI (multiple drugs, mostly … In particular, there are sparse RCTs or NRCSs that evaluated antiplatelet drugs (e.g., aspirin), VKA

412. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
     September 01, 2009 - Administration (FDA), information packages submitted by the pharmaceutical companies marketing lipid- modifying drugs … , and the Internet. 3 Study Selection Studies employing therapeutic doses of drugs were included … Relevant nonstatin hypolipidemic drugs included ezetimibe, fibrates, niacin, BAS, and omega-3 fatty acids … Synthesis of evidence was specific to combinations employing different nonstatin hypolipidemic drugs.

413. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
     July 18, 2011 - A variety of selective 5-HT1 receptor agonists have been developed and represent a class of drugs called … emergency department; NRCT = nonrandomized controlled trial; NSAIDs = nonsteroidal anti-inflammatory drugs … race, use of concurrent pharmacological interventions), details of the intervention and comparator (drugs … (cephalgi$ or cephalalgi$).tw. 9. or/1-8 Terms for drugs used to treat acute migraine 10. exp serotonin

414. Disposition of Comments CER 219 Antipsychotics for the Prevention and Treatment of Delirium (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
     September 03, 2019 - We now state, “Although the drugs may have different mechanisms of action, we anticipated that most … drugs within a class would have similar clinical effects. … discussing the synthesis of the data, the draft report notes that “Since we anticipated that most drugs … We now state, “Although the drugs may have different mechanisms of action, we anticipated that most … drugs within a class would have similar clinical effects.

415. App-F2-Surv-Report-1-Nonopioid-Pharmacol-Chronic-Pain (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
     October 08, 2025 - TCA_PCT Table F-2a. Harms of tricyclic antidepressants versus placebo Author, Year Quality Pain Population Drug Class Drug Assessment Time (Wk) Time Category WAE: n WAE: N SAE: n SAE: N Cardiac Rhythm Abnormalities: Specific AE Cardiac Rhythm Abnormalities: n Cardiac Rhythm Abnormalities: N N Randomized Cognitive Eff…

416. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
     December 11, 2012 - Status UA/NSTEMI-Related FDA Indications Plavix® Clopidogrel Bristol Myers Squibb Sanofi Pharmaceuticals … thrombotic CV events in patients with ACS (UA, NSTEMI, STEMI) Arixtra® Fondaparinux GlaxoSmithKline Pharmaceuticals … in patients with nonvalvular atrial fibrillation Pradaxa® Dabigatran Boehringer Ingelheim Pharmaceuticals … Pfizer 2.5 mg 5 mg Twice daily Oral Not currently FDA approved Protonix® Pantoprazole Wyeth Pharmaceuticals … patients on dual antiplatelet therapy to reduce the risk of bleeding Prevacid® Lansoprazole Takeda Pharmaceuticals

417. Systematic Review on Nonopioid Pharmacologic Treatments for Chronic Pain: Surveillance Report 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
     April 01, 2022 - Conclusions Nonopioid drugs (mainly serotonin-norepinephrine reuptake inhibitor [SNRI] antidepressants … , pregabalin/gabapentin, and nonsteroidal anti-inflammatory drugs [NSAIDs]) resulted in small to moderate … patients with specific types of noncancer chronic pain in the short term, with few differences between drugs … Interventions • Oral pharmacologic agents: nonsteroidal anti-inflammatory drugs, acetaminophen, muscle … events, cardiovascular events, and liver or kidney-related harms for non- steroidal anti-inflammatory drugs

418. App-F2-Surv-Report-3-Nonopioid-Pharmacol-Chronic-Pain (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
     October 08, 2025 - TCA_PCT Table F-2a. Harms of tricyclic antidepressants versus placebo Author, Year Quality Pain Population Drug Class Drug Assessment Time (Wk) Time Category WAE: n WAE: N SAE: n SAE: N Cardiac Rhythm Abnormalities: Specific AE Cardiac Rhythm Abnormalities: n Cardiac Rhythm Abnormalities: N N Randomized Cognitive Eff…

419. Mobile Health Technology for Diabetes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-mobile-devices_research-protocol.pdf
     July 12, 2017 - product tables such as those published by the AHRQ Eisenberg Center11 and Consumer Report’s Best Buy Drugs … Consumer Reports, Best Buy Drugs. Best treatments for depression.

420. Disposition of Comments for Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
     April 22, 2013 - Further, adverse effects of antipsychotic drugs have been thoroughly summarized in existing systematic … We have revised the document to emphasize the specific drugs evaluated within classes, paying particular … name amantadine We have revised the key points, results, and SOE table to emphasize the specific drugs … We also reviewed the document to ensure consistency in how drugs were classified. … We acknowledge that some drugs are not readily classified or could be classified in more than one