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Showing results for "drugs".

41. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0264_01-14-2008.pdf
    January 01, 2008 - Summary: The nominator questions the comparative effectiveness of disease-modifying antirheumatic drugs … idiopathic arthritis Intervention(s): Corticosteroids; Synthetic disease-modifying anti-rheumatic drugs … intramuscular gold); biologic DMARDs (i.e., etanercept, infliximab, adalimumab, anakinra) Excluded drugs … penicillamine (toxicity), oral gold (marginal efficacy), chloroquine and hydroxychloroquine (antimalarial drugs

42. Evaluation of Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
    February 01, 2008 - Antiepileptic Drugs. Fifth ed. … Antiepileptic Drugs. Fourth ed. New York, Raven Press; 1995. p. 799-806. 19. … Antiepileptic Drugs. Fifth ed. … Therapeutic equivalence of generic drugs letter to health practitioners. … Are there potential problems with generic substitution of antiepileptic drugs?

43. #05 DEPRESSION (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Available: http://www.cesar.umd.edu/cesar/drugs/ketamine. pdf. 4. … CNS Drugs. 2012 Mar 1;26(3):189-204. … http://www.cesar.umd.edu/cesar/drugs/ketamine.pdf http://www.cesar.umd.edu/cesar/drugs/ketamine.pdf http … Rochester (MI): JHP Pharmaceuticals, LLC; 2011 Jun. 4 p.

44. Nonopioid Pharmacologic Treatments for Chronic Pain: Evidence Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
    April 01, 2020 - for Chronic Pain: Evidence Summary Purpose of Review Evaluate the benefits and harms of nonopioid drugs … neuropathy/post-herpetic neuralgia and fibromyalgia, and small with nonsteroidal anti-inflammatory drugs … (NSAIDs), acetaminophen, topical formulations such as capsaicin, and drugs used for other conditions … Few differences were found between drugs. … Differences were not found between drugs or doses.

45. #06 Developmental Delays ADHD, and Autism (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … These drugs will probably face intense scrutiny, considering the challenges of accurately diagnosing

46. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
    January 01, 2007 - Available therapies for RA include corticosteroids; synthetic disease-modifying antirheumatic drugs, … Finally, very little is known about the benefits or risks of these drugs in different patient subgroups … : comparative risk of harms: infliximab) vs. anti-TNF Moderate Low drugs Biologic DMARDs vs. … Moderate Moderate In patients with no previous use of study drugs, higher ACR 20/50 response rates … Adjusted indirect comparisons also indicated that anakinra has lower efficacy than anti-TNF drugs.

47. Dietary-Supplements Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
    April 01, 2012 - Comparative Effectiveness Review Number 51 Dietary Supplements in Adults Taking Cardiovascular Drugs … (when compared with cardiovascular drugs alone or cardiovascular drugs and a different dietary supplement … • Studies included cardiovascular drugs not marketed in the United States. … Drugs Aging. 2009 Dec;26(Suppl 1):41-51. PMID: 20136168. 13. Garner JB. … Dietary Supplements in Adults Taking Cardiovascular Drugs.

48. DEcIDE 32: The Incident User Design in Comparative Effectiveness Research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
    May 01, 2012 - ...............................................................................3 Recently Marketed Drugs … If newer drugs were started more recently, the newer drugs may appear safer than older drugs because … their apparent rate would be lower; investigators would observe a higher event rate for older drugs … in a class; requiring all patients in the cohort to have a 365-day window without use of any drugs … For drugs that are available as combination products, it is important to handle the baseline period

49. PULMONARY with "Discussions" in Exec Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - Boston (MA): Vertex Pharmaceuticals, Inc.; 2014 Nov 05 [accessed 2014 Dec 11]. [3 p]. … Boston (MA): Vertex Pharmaceuticals Incorporated [accessed 2015 Dec 10]. [2 p]. … MannKind Corporation, Takeda Pharmaceuticals America, Inc, Genentech USA, Inc. … Boehringer Ingelheim Pharmaceuticals, Inc. … Ridgefield (CT): Boehringer Ingelheim Pharmaceuticals, Inc.; 2014 Oct. 18 p.

50. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
    November 03, 2011 - The FDA has approved no drugs for migraine prevention in children. … prevention, which include novel antiepileptic drugs, calcium channel modulators, glutamate blockers … o Use of drugs for acute migraine (prescribed or over-counter). … Drugs approved by the FDA for migraine prevention and off-label drugs examined in clinical trials. … Studies that examined eligible drugs on populations with other diseases.

51. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
    September 01, 2011 - Disease-Modifying Antirheumatic Drugs (DMARDs) in Children With Juvenile Idiopathic Arthritis (JIA) … Treatment with the class of agents known as disease-modifying anti- rheumatic drugs (DMARDs) has become … , which are created by biologic processes, or non-biologic drugs, which are manufactured chemically. … Furthermore, it is possible that the effectiveness of these drugs varies by category of JIA. … be used for difficult-to-treat JIA, or the impact of using multiple drugs.

52. Obesity (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - Given the limited pharmacologic treatment options for obesity, additional pharmaceuticals intended … San Diego (CA): Arena Pharmaceuticals, Inc; 2010 Nov 09 [accessed 2011 Dec 16]. [3 p]. … Washington (DC): Arena Pharmaceuticals, Inc.; 2009 Oct 27 [accessed 2011 Apr 21]. [4 p]. … San Diego (CA): Arena Pharmaceuticals, Inc.; 2010 Jul 01 [accessed 2014 Apr 29]. [3 p]. … San Diego (CA): Arena Pharmaceuticals; 2012 Jun 27 [accessed 2012 Jul 05]. [4 p].

53. Cover Page (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
    September 01, 2007 - For example, although 15 drugs were withdrawn from the market between 1997 and 2005 based on MedWatch … The surveillance administration process involves the identification of newly introduced drugs that … No effective mechanism currently exists for tracking the purchase of such drugs. … Such dispensation of drugs by the physicians may need to be monitored, especially for drugs that have … In order to cater to this need, all drugs taken by patients will need to be monitored.

54. Cover Page (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
    September 01, 2007 - For example, although 15 drugs were withdrawn from the market between 1997 and 2005 based on MedWatch … The surveillance administration process involves the identification of newly introduced drugs that … No effective mechanism currently exists for tracking the purchase of such drugs. … Such dispensation of drugs by the physicians may need to be monitored, especially for drugs that have … In order to cater to this need, all drugs taken by patients will need to be monitored.

55. S29 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s29.pdf
    October 01, 2007 - it involved 2 short-term drugs instead of 2 long-term drugs? … Changes could also confuse physicians; confusion could generalize beyond the study drugs. … Some leaders noted that newer drugs are not typically included on their formulary. … Including short term drugs would be more challenging. … Make clear that physicians have flexibility to prescribe nonstudy drugs.

56. Evidence Summary for CER 239: Acute Treatments for Episodic Migraine (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
    December 01, 2020 - Points • Compared with placebo, treatments such as triptans, NSAIDs (nonsteroidal anti- inflammatory drugs … Some opioids may be less effective than other drugs. … Results Evidence on triptans and nonsteroidal anti-inflammatory drugs (NSAIDs) was summarized from … In terms of applicability, several of the established drugs, such as the ergot alkaloids, may not be … In general, adverse events of these drugs are mild and transient.

57. Obesity (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
    July 01, 2013 - San Diego (CA): Arena Pharmaceuticals, Inc; 2010 Nov 9 [accessed 2011 Dec 16]. [3 p]. … Washington (DC): Arena Pharmaceuticals, Inc.; 2009 Oct 27 [accessed 2011 Apr 21]. [4 p]. … San Diego (CA): Arena Pharmaceuticals, Inc.; 2009 Dec 22 [accessed 2012 Mar 26]. [2 p]. … San Diego (CA): Arena Pharmaceuticals; 2012 Jun 27 [accessed 2012 Jul 5]. [4 p]. … Arena Pharmaceuticals. Lorcaserin hydrochloride. Drugs Future. 2007;32(9):766-70. 77.

58. PULMONARY with "Discussions" in Exec Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1412.pdf
    October 01, 2015 - Cambridge (MA): Vertex Pharmaceuticals, Inc.; 2011 Nov 03 [accessed 2014 Apr 10]. [4 p]. … Cambridge (MA): Vertex Pharmaceuticals, Inc.; 2010 Nov 08 [accessed 2011 Jan 04]. [1 p]. … Boston (MA): Vertex Pharmaceuticals, Inc.; 2014 Nov 05 [accessed 2014 Dec 11]. [3 p]. … Boehringer Ingelheim Pharmaceuticals, Inc. … Ridgefield (CT): Boehringer Ingelheim Pharmaceuticals, Inc.; 2014 Oct. 18 p.

59. Rapid Evidence Product: Misuse of ADHD Prescription Stimulants in Adults (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-adhd-prescription-rapid-research.pdf
    July 01, 2025 - Misuse of Prescription Drugs Research Report. 2023. … https://nida.nih.gov/publications/research -reports/misuse-prescription- drugs/overview. … initiated prescription stimulants alone or at the same age as other drugs. … A relatively small percentage “because they are safer than street drugs.” How acquired? … , 31% used them with alcohol or illicit drugs.

60. #06 Developmental Delays ADHD, and Autism (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_autism_potential_high_impact_june_2012.pdf
    January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … These drugs will likely face intense scrutiny, considering the challenges of accurately diagnosing