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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
    September 15, 2008 - conduct and support research on the comparative outcomes, clinical effectiveness, and appropriateness of pharmaceuticals … support research with a focus on outcomes, comparative clinical effectiveness, and appropriateness of pharmaceuticals … MedWatch database and the Canadian Health Services (CHS) pharmaceutical database for any reports about drugs
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-use-disorder_disposition-comments.pdf
    December 06, 2016 - and SUBUTEX® (buprenorphine HCl, sublingual tablet), available at: http://www.fda.gov/downloads/Drugs … NASTAD works to bolster health department support for MAT with people who inject drugs (PWID) through … a sharpening of our focus so that we can prevent new infections and overdose among people who use drugs … Penner General Thank you for supporting opportunities to improve the lives of people who use drugs … Primary care patients with drug use report chronic pain and self-medicate with alcohol and other drugs
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
    May 29, 2025 - TCA_PCT Table F-2a. Harms of tricyclic antidepressants versus placebo Author, Year Quality Pain Population Drug Class Drug Assessment Time (Wk) Time Category WAE: n WAE: N SAE: n SAE: N Cardiac Rhythm Abnormalities: Specific AE Cardiac Rhythm Abnormalities: n Cardiac Rhythm Abnormalities: N N Randomized Cognitive Eff…
  4. effectivehealthcare.ahrq.gov/sites/default/files/mcda-ijzerman.pdf
    January 01, 2011 - Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis (MCDA) and Conjoint Analysis (CA) Slide 1 Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis (MCDA) and Conjoint Analysis (CA) Maarten J…
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
    January 01, 2007 - conduct and support research on the comparative outcomes, clinical effectiveness, and appropriateness of pharmaceuticals … - When used in pregnancy during the second and third trimesters, drugs that act directly on the … Different effect of antihypertensive drugs on conduit artery endothelial function. … Tolerability of antihypertensive drugs in a community-based setting. … Long-term persistence with antihypertensive drugs in new patients.
  6. S77 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
    October 01, 2007 - number of prescriptions filled for 30-day periods, we are unable to calculate the actual use of generic drugs … a sliding-scale basis for this group, and because copayments are tied to the cost of their specific drugs
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
    October 01, 2010 - Catheter Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation: The A4 Study. Circulation. … Catheter ablation versus antiarrhythmic drugs for atrial fibrillation: The A4 Study. … It concluded that AF ablation was superior to anti-arrhythmic drugs in paroxysmal AF patients, helping … Catheter ablation versus antiarrhythmic drugs for atrial fibrillation: The A4 Study. … Catheter Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation: The A4 Study.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
    May 29, 2025 - TCA_PCT Table F-2a. Harms of tricyclic antidepressants versus placebo Author, Year Quality Pain Population Drug Class Drug Assessment Time (Wk) Time Category WAE: n WAE: N SAE: n SAE: N Cardiac Rhythm Abnormalities: Specific AE Cardiac Rhythm Abnormalities: n Cardiac Rhythm Abnormalities: N N Randomized Cognitive Eff…
  9. effectivehealthcare.ahrq.gov/sites/default/files/thromboembolism-update-executive-170622.pdf
    June 01, 2017 - The modalities can be used alone or in combination, at variable doses (of drugs) or regimens (of mechanical … history of abnormal surgical bleeding or bleeding disorder, prior medications (e.g., antiplatelet drugs … Studies evaluated the following thromboprophylaxis classes (and combinations thereof): antiplatelet drugs … Among four RCTs of low versus high dose FXaI, studies favored higher dose FXaI (multiple drugs, mostly … In particular, there are sparse RCTs or NRCSs that evaluated antiplatelet drugs (e.g., aspirin), VKA
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-executive-170622.pdf
    June 01, 2017 - The modalities can be used alone or in combination, at variable doses (of drugs) or regimens (of mechanical … history of abnormal surgical bleeding or bleeding disorder, prior medications (e.g., antiplatelet drugs … Studies evaluated the following thromboprophylaxis classes (and combinations thereof): antiplatelet drugs … Among four RCTs of low versus high dose FXaI, studies favored higher dose FXaI (multiple drugs, mostly … In particular, there are sparse RCTs or NRCSs that evaluated antiplatelet drugs (e.g., aspirin), VKA
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
    June 01, 2022 - support the conclusions from the original report that triptans and nonsteroidal anti- inflammatory drugs … Results from included studies: KQ 2, nonsteroidal anti-inflammatory drugs ............ … versus: (1) nonopioid pharmacologic therapy (e.g., acetaminophen, nonsteroidal anti-inflammatory drugs … Abbreviations: ED = emergency department; KQ = Key Question; NSAID = nonsteroidal anti-inflammatory drugs … Results from included studies: KQ 2, nonsteroidal anti-inflammatory drugs Author, Year, Study Design
  12. effectivehealthcare.ahrq.gov/sites/default/files/crosscutting_hi_impact.pdf
    January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … It differentiated 100% of multiple drugs and doses taken simultaneously by type and by dose.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
    February 10, 2016 - role  of   perioperative  anti-­inflammatory  medications  (e.g.,  non-­steroidal  anti-­inflammatory  drugs … Appendix  A   outlines  manufacturers  of  key  device  and  drugs  used  to  treat  the  population   … or  obstructive  sleep-­disordered   breathing  may  include  use  of  the  following  classes  of  drugs … Some  drugs  are  not  recommended  in  younger   children  (e.g.,  diphenhydramine)  as  they  may   … Leukotriene  inhibitors:  These  drugs  are  FDA-­approved  to  treat  asthma  symptoms  in  children
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
    January 01, 2015 - Treatment components may include drugs, exercise programs, cognitive behavioral therapy (CBT), patient … In addition, numerous drugs approved for other conditions are currently used off label in patients … Pharmacolgic, nonpharmocologic, or multimodal treatments Adverse effects of drugs or interventions … We excluded studies of drugs not FDA approved in the United States for any condition; studies that … Subgroup Outcomes In this section, we first examine the effect of drugs on various subgroups and then
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-therapy-management_executive.pdf
    November 01, 2014 - require multiple chronic conditions or a minimum number or level of expenditures on prescription drugs … following 3 elements: – Comprehensive medication review covering all prescription and nonprescription drugs … Proximal and intermediate outcomes included number of drugs, identification of drug therapy problems … Drugs. 2009;69(4):393-406. Epub: 2009/03/28. PMID: 19323584. 10. 108th U.S. Congress.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
    May 01, 2022 - Opioid therapy versus nonopioid pharmacologic therapy (acetaminophen, non-steroidal anti-inflammatory drugs … CNS Drugs. 2021;35(1):105-20. doi: 10.1007/s40263- 020-00777-7. PMID: 33428176. … The treatment of topical drugs for postherpetic neuralgia: a network meta-analysis. … Canadian Agency for Drugs and Technologies in Health. 2021 PMID: 34185448. … Non-steroidal anti- inflammatory drugs for acute low back pain.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-computerized-cds-protocol.pdf
    May 08, 2023 - EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review 1 Evidence-based Practice Center Rapid Review Protocol Project Title: Making Healthcare Safer IV: Computerized Clinical Decision Support to Prevent Medication Errors and Adverse Drug Events Review …
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-adherence_research-protocol.pdf
    September 13, 2011 - infected blood.4 The most common mode of HCV transmission in the United States is the use of injection drugs … These new agents may be used in combination with existing antiviral drugs, and the duration of treatment … ribavirin and interferon doses, taking greater than 80 percent of the required dosage of one or both drugs … Additionally, we will request Scientific Information Packets from manufacturers of relevant drugs, devices … We will record the generic names of the drugs used to treat the intervention and control groups, dose
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence-quiz.ppt
    May 29, 2025 - good source of information for planning future research and may provide some preliminary data on new drugs
  20. effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence-quiz.ppt
    May 29, 2025 - good source of information for planning future research and may provide some preliminary data on new drugs

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