-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting_hi_impact.pdf
January 01, 2012 - Coordinating Council for Comparative Effectiveness Research,
AHRQ is interested in innovations in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar
drugs in the … It differentiated 100% of multiple
drugs and doses taken simultaneously by type and by dose.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - have been diagnosed
with delirium using a validated instrument
• Interventions:
o Antipsychotic drugs … , risperidone, ziprasidone)
o We will only include studies where the effects of the antipsychotic drugs … quetiapine,
risperidone, ziprasidone)
• We will exclude studies where the
effects of the antipsychotic drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
October 08, 2025 - NPP_Pain
Table F-1a. Pain severity for neuropathic pain
Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug 1 Drug 2 Measure Name Measure Scale Assessment Time (Wk) Time Category Grp 1 Baseline N Grp 1 Baseline Mean Pain Score Grp1 Baseline Variance Type Grp1 Baseline Variance Grp1 Baseline Lower Limi…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
January 01, 2015 - Treatment
components may include drugs, exercise programs,
cognitive behavioral therapy (CBT), patient … In addition, numerous drugs
approved for other conditions are currently used off label
in patients … Pharmacolgic,
nonpharmocologic, or
multimodal treatments
Adverse effects of
drugs or interventions … We
excluded studies of drugs not FDA approved in the United
States for any condition; studies that … Subgroup Outcomes
In this section, we first examine the effect of drugs on
various subgroups and then
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
February 10, 2016 - role of
perioperative anti-inflammatory medications (e.g., non-steroidal anti-inflammatory drugs … Appendix A
outlines manufacturers of key device and drugs used to treat the population … or obstructive sleep-disordered
breathing may include use of the following classes of drugs … Some drugs are not recommended in younger
children (e.g., diphenhydramine) as they may … Leukotriene inhibitors: These drugs are FDA-approved to treat asthma symptoms in children
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
May 01, 2022 - Opioid therapy versus nonopioid pharmacologic therapy (acetaminophen, non-steroidal
anti-inflammatory drugs … CNS Drugs.
2021;35(1):105-20. doi: 10.1007/s40263-
020-00777-7. PMID: 33428176. … The treatment
of topical drugs for postherpetic neuralgia: a
network meta-analysis. … Canadian Agency for
Drugs and Technologies in Health. 2021
PMID: 34185448. … Non-steroidal anti-
inflammatory drugs for acute low back pain.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-adherence_research-protocol.pdf
September 13, 2011 - infected blood.4 The most common mode of HCV
transmission in the United States is the use of injection drugs … These new agents may be
used in combination with existing antiviral drugs, and the duration of treatment … ribavirin and interferon doses, taking greater than 80 percent of
the required dosage of one or both drugs … Additionally, we will request Scientific Information Packets from manufacturers of relevant
drugs, devices … We will record the generic names of
the drugs used to treat the intervention and control groups, dose
-
effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence-quiz.ppt
October 08, 2025 - good source of information for planning future research and may provide some preliminary data on new drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence-quiz.ppt
October 08, 2025 - good source of information for planning future research and may provide some preliminary data on new drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
September 15, 2008 - conduct and support research on the comparative outcomes, clinical
effectiveness, and appropriateness of pharmaceuticals … support research with a focus on outcomes, comparative clinical effectiveness,
and appropriateness of pharmaceuticals … MedWatch database and the
Canadian Health Services (CHS) pharmaceutical database for any reports about drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/diverticulitis-nomination-extra.pdf
October 08, 2025 - Management of Acute Diverticulitis Additional Information for Topic Nomination
Table 1. Key Questions and PICOTS
KQ1: Antibiotics KQ1: Antibiotics vs.
No Antibiotics
KQ2: Diagnostic
imaging
KQ3: Follow-up
colonoscopy
KQ4: Surgical and
interventional
management
KQ5: Prevention of
recurrence
Populat…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/deprescribing-protocol.pdf
July 01, 2023 - approach, known as deprescribing, is defined as a “systematic process of
identifying and discontinuing drugs … Drugs Aging. 2013 Oct;30(10):793-807. doi: 10.1007/s40266-013-0106-8. PMID:
23912674.
10.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
October 01, 2021 - preferred treatment of chronic pain.1,2 However, recent
systematic reviews found that several nonopioid drugs … qualitative and
indirect comparisons with very limited evidence on cannabis products relative to the
other drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/searching.ppt
January 01, 2011 - Ottawa: Canadian Agency for Drugs and Technologies in Health; 2008. … Ottawa: Canadian Agency for Drugs and Technologies in Health; 2008. … or may be incompletely published elsewhere
Good check for publication bias
Regulatory Web sites:
Drugs … That is because the approval process for new drugs and devices requires submission of data that may not … Ottawa: Canadian Agency for Drugs and Technologies in Health; 2008.
Sassi F, Archard L, McDaid D.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tinnitus_research-protocol.pdf
February 22, 2012 - Tinnitus can also be a side effect of potentially ototoxic drugs, ranging from
aspirin taken to alleviate … arthritic pain to aminoglycoside antibiotics and life-saving drugs used to treat
cancer.4 These effects … While drugs are used for tinnitus, there is no drug that has been approved
specifically for its treatment … Behavioral methods should be used before considering the use of drugs. … Drugs can be used to treat comorbid conditions such as anxiety and depression.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
July 01, 2009 - (cross-walked) to one of several
coding systems; ICD-9 CM for diagnoses, RxNORM and GCN codes for drugs … of
SNOMED CT versus commercially available drug codes for group classifications and
combination drugs … the DARTNet Diabetes Replication Cohort was generally similar to those seen
in phase 1 related to drugs … study will describe the patterns of use of
antidepressants and combinations of other psychotropic drugs … research, DARTNet’s ultimate aim is to improve the understanding of the effectiveness
of various drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-covid-appendix-a.pdf
December 01, 2022 - Physical Medicine & Rehabilitation; ACC = American College of Cardiology; CADTH = Canadian Agency for Drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
October 08, 2025 - TCA_PCT
Table F-2a. Harms of tricyclic antidepressants versus placebo
Author, Year Quality Pain Population Drug Class Drug Assessment Time (Wk) Time Category WAE: n WAE: N SAE: n SAE: N Cardiac Rhythm Abnormalities: Specific AE Cardiac Rhythm Abnormalities: n Cardiac Rhythm Abnormalities: N N Randomized Cognitive Eff…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-risk-reduction_research.pdf
October 25, 2010 - conduct and support research on the comparative
outcomes, clinical effectiveness, and appropriateness of pharmaceuticals … Drugs based on a person's genetics 37.5%
(3)
50.0%
(4)
12.5%
(1) Q12. … Gene-based drugs 54.5%
(6)
9.1%
(1)
36.4%
(4)
Q12. … Drugs that target specific molecular cancer
pathways
62.5%
(5)
37.5%
(3)
0
(0) Q13. … Randomized controlled trials I
Drug development 224
Molecular targeted
drugs specific to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-prepub-final-research-appendix-c.xlsx
January 01, 2024 - health legume allergy; milk or lactose intolerance; chronic diseases; pregnancy; lactation; intake of pharmaceuticals … lactose intolerance, chronic bowel diseases, pregnancy, lactation, and the intake of blood lipid–lowering pharmaceuticals … funding of study NR 18–55 years, BMI: 18.5-30 kg/m2, healthy and free of chronic diseases, avoid any pharmaceuticals … Antibiotics, anti-inflammatory/immune suppressive drugs and spasmolytics use.* (e.g. hospital or nursing … Antibiotics, anti-inflammatory/immune suppressive drugs and spasmolytics use. 4 wk 4-6 wk 28/28 d Days