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Showing results for "drugs".

361. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
     June 01, 2010 - patients to be new users of the specific cohort-defining drug or new users of the entire class of drugs … biased observational studies require all patients in the cohort to be new users of the entire class of drugs … Gaps in the evaluation and monitoring of new pharmaceuticals: proposal for a different approach. … Drug class review: atypical antipsychotic drugs, Final report update 2. In: Helfand M, ed. … patients with schizophrenia initiating treatment with an atypical antipsychotic medication, which drugs

362. Use of Observational Studies in Systematic Reviews of (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
     June 01, 2010 - patients to be new users of the specific cohort-defining drug or new users of the entire class of drugs … biased observational studies require all patients in the cohort to be new users of the entire class of drugs … Gaps in the evaluation and monitoring of new pharmaceuticals: proposal for a different approach. … Drug class review: atypical antipsychotic drugs, Final report update 2. In: Helfand M, ed. … patients with schizophrenia initiating treatment with an atypical antipsychotic medication, which drugs

363. Antipsychotics-Children Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
     June 04, 2010 - We were asked to study the use of these drugs for the following conditions: 1) pervasive developmental … Intervention drugs of interest The intervention drug must be an FDA-approved first or second generation … These drugs include: aripiprazole, asenapine, clozapine, iloperidone, olanzapine, paliperidone, quetiapine … Comparison drugs of interest http://www.effectivehealthcare.ahrq.gov/� Source: www.effectivehealthcare.ahrq.gov … co-morbidities, use of concurrent standard medical therapies), details of the intervention and comparator (drugs

364. Abnormal-Uterine-Bleeding Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
     November 21, 2011 - progestogens, combination (estrogen and progestogen) hormonal formulations, nonsteroidal anti-inflammatory drugs … longer commonly prescribed for related indications (e.g., the synthetic androgen– Danazol) nor for drugs … Interventions 1 :  Medical therapies o Nonsteroidal anti-inflammatory drugs o Antifibrinolytics … compounds that are no longer commonly prescribed, such as the synthetic androgen Danazol, as well as drugs … Interventions for Abnormal Uterine Bleeding Nonsteroidal anti-inflammatory drugs (NSAIDs)  Ibuprofen

365. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
     February 17, 2016 - history of abnormal surgical bleeding or bleeding disorder, prior medications (including antiplatelet drugs … of abnormal surgical bleeding or bleeding disorder o   Prior medications (especially antiplatelet drugs … surgical   bleeding   History  of  bleeding  disorder   Prior  medications  (especially   antiplatelet  drugs … Available drugs are anticoagulants that lower the likelihood that blood clots.

366. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label_executive.pdf
     January 01, 2007 - These drugs have been studied for off-label use in the following conditions: dementia and severe geriatric … How do atypical antipsychotic medications compare with other drugs for treating off- label indications … Effectiveness and comparison with other drugs Dementia-agitation and behavioral disorders A recent … Both drugs were associated with an increase in EPS (OR: 2.53 and 2.82, respectively) compared to placebo

367. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Results The table below lists the two topics for which (1) preliminary phase III data for drugs or

368. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
     July 13, 2011 - These drugs work, at least in part, through their effects on neurotransmitters such as serotonin, norepinephrine … somatization), KQ4 focuses on safety issues (adverse effects, adherence) with each of the different study drugs … or combinations of study drugs.

369. S143 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
     October 01, 2007 - Key Words: cohort studies, propensity scores, observational research (Med Care 2007;45: S143–S148) Drugs … Statins inhibit endogenous cholesterol synthesis, and ther- apy with these drugs improves lipoprotein … including ambulatory care, approved specialists and outside referrals, laboratory work, and prescription drugs

370. Rapid Response_The Association Between Outcomes and Dental Services in Persons With Autoimmune Disease Treated With Biologics and Other Immunosuppressants: A Rapid Response Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autoimmune-disease-rapid-research.pdf
     November 01, 2024 - studies had patients who were on either conventional or biologic disease-modifying anti-rheumatic drugs … A class of therapeutic agents called DMARDs (disease-modifying anti-rheumatic drugs) has been in use … yr 12.2% Abbreviations: csDMARDs: conventional synthetic disease-modifying anti-rheumatic drugs … ; DMARDs: disease-modifying anti-rheumatic drugs; mo: month; NR: not reported; NSAIDs: nonsteroidal … Mechanisms of Action of Disease Modifying Antirheumatic Drugs. J Rheumatol Suppl 1992, 32, 100–103

371. Calcineurin_Inhibitors_Protocol_FINAL_10-07-2014 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
     October 08, 2014 - amount of drug administered early or late post- transplant; 4) CNI avoidance, which substitutes other drugs … Safety of immunosuppressive drugs used as maintenance therapy in kidney transplantation: a systematic … Pharmaceuticals. 2013;6(10):1170-94. Also available: http://dx.doi.org/10.3390/ph6101170. … relies on antibodies binding to specific antigens; frequently used to measure levels of therapeutic drugs … in a biologic sample Nephrotoxicity: exposure of the kidneys to poisonous (toxic) chemicals; many drugs

372. Data-Points-9 Maps (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/data-points-9_maps.pdf
     October 08, 2025 - Utilization of Sulfonylureas per 100 Diabetic Medicare Beneficiaries With Continuous Enrollment in Parts A and B FFS and Part D, by Hospital Referral Region (HRR), 2006-2009 Annual Utilization of Sulfonylureas Among Diabetic Beneficiaries With At Least One Antidiabetic Drug Order, by HRR, 2006 Annual Util…

373. Medication-Therapy-Management Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
     January 01, 2014 - programs target Medicare Part D enrollees, who have multiple chronic diseases, are taking multiple Part D drugs … , and are likely to incur annual costs for covered Part D drugs that exceed a predetermined level (“ … A plan may require no more than eight Part D drugs, although they may set at the maximum at any number … personal medication report, which is a written list of the patient’s prescription and nonprescription drugs … Drugs. 2009;69(4):393-406. PMID: 19323584. 3. Lewin Group.

374. Topic 0494 Tacrolimus Monitoring and Treatment Renal Transplantation NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0583-131115.pdf
     March 13, 2013 - A systematic review will outline the most effective choices among new drugs and monitoring strategies

375. Disposition of Comments for Technical Brief 28 MAT Models (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-use-disorder_disposition-comments.pdf
     December 06, 2016 - and SUBUTEX® (buprenorphine HCl, sublingual tablet), available at: http://www.fda.gov/downloads/Drugs … NASTAD works to bolster health department support for MAT with people who inject drugs (PWID) through … a sharpening of our focus so that we can prevent new infections and overdose among people who use drugs … Penner General Thank you for supporting opportunities to improve the lives of people who use drugs … Primary care patients with drug use report chronic pain and self-medicate with alcohol and other drugs

376. Identification and Treatment of Post-Acute Coronary Syndrome (ACS) Depression: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
     February 15, 2017 - Appendix A: FDA Status and Warnings for Drugs … Vintage Pharmaceuticals,LLC, Huntsville, AL, 2006. 9. … Teva Pharmaceuticals USA, Inc. (per FDA), Horsham, PA, 2014. 19.

377. Microsoft Word - Comp Eff 10.doc (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
     January 01, 2007 - conduct and support research on the comparative outcomes, clinical effectiveness, and appropriateness of pharmaceuticals … - When used in pregnancy during the second and third trimesters, drugs that act directly on the … Different effect of antihypertensive drugs on conduit artery endothelial function. … Tolerability of antihypertensive drugs in a community-based setting. … Long-term persistence with antihypertensive drugs in new patients.

378. App-F1-Surv-Report-1-Nonopioid-Pharmacol-Chronic-Pain (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
     October 08, 2025 - NPP_Pain Table F-1a. Pain severity for neuropathic pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug 1 Drug 2 Measure Name Measure Scale Assessment Time (Wk) Time Category Grp 1 Baseline N Grp 1 Baseline Mean Pain Score Grp1 Baseline Variance Type Grp1 Baseline Variance Grp1 Baseline Lower Limi…

379. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
     October 01, 2010 - Catheter Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation: The A4 Study. Circulation. … Catheter ablation versus antiarrhythmic drugs for atrial fibrillation: The A4 Study. … It concluded that AF ablation was superior to anti-arrhythmic drugs in paroxysmal AF patients, helping … Catheter ablation versus antiarrhythmic drugs for atrial fibrillation: The A4 Study. … Catheter Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation: The A4 Study.

380. App-F1-Surv-Report-2-Nonopioid-Pharmacol-Chronic-Pain (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f1-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
     October 08, 2025 - NPP_Pain Table F-1a. Pain severity for neuropathic pain Author, Year Quality Pain Population Drug Class 1 Drug Class 2 Drug 1 Drug 2 Measure Name Measure Scale Assessment Time (Wk) Time Category Grp 1 Baseline N Grp 1 Baseline Mean Pain Score Grp1 Baseline Variance Type Grp1 Baseline Variance Grp1 Baseline Lower Limi…