-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
December 06, 2010 - Available therapies for RA include
corticosteroids, oral disease-modifying antirheumatic drugs (DMARDs … Finally, very little is known about the
benefits or risks of these drugs AMONG different patient subgroups … review did not include certolizumab pegol, golimumab,
and tocilizumab (listed above), because these drugs … Golimumab Simponi®
Tocililizumab Actemra®, RoActemrai®
• Comparators:
For all KQs: all review drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
October 01, 2007 - Rapid Cycle
Analysis Team
Background: Rare but serious adverse events associated with vac-
cines or drugs … meningococcal vaccine, drug safety
(Med Care 2007;45: S89–S95)
Concerns about the safety of vaccines and drugs … the
Centers for Disease Control and Prevention (CDC) and Food
and Drug Administration (FDA) and, for drugs … In addition, because drugs treat specific conditions, the pool
of users for a new medication is limited … early detection of potential adverse events after the
introduction of new vaccines, and possibly new drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
October 01, 2007 - controlled trials (RCTs) remain the ac-
cepted “gold standard” for determining the efficacy of new drugs … Follow-up and monitoring is
designed to promote adherence to the drugs under study and
to detect any … Drug coverage—Which bisphosphonate drugs should be included on a
drug fomulary? … , quality of intervention
Timing of intervention
Cointerventions, quality of care
Adherence (for drugs … Treatment with drugs to lower
blood pressure and blood cholesterol based on an individual’s absolute
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-adults-and-children-with-asthma-what-is-the-effectiveness-of-the-buteyko-breathing-method-on-reducing-bronchodilator-and-inhaled-steroid-use-and-improving-health-status
September 01, 2009 - no
If yes, explain the specific technologies, devices, drugs, or interventions you would like to
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-all-patients-addressing-continuum-of-care-has-research-analysis-been-performed-to-promote-the-benefit-of-certified-nurse-case-managers-working-with-physicians-to-promote-appropriate-utilization-of-services-and-to-facilita
March 10, 2009 - no
If yes, explain the specific technologies, devices, drugs, or interventions you would like to
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/this-survey-would-about-early-warning-signs-of-multiple-sclerosis-which-i-documented-as-late-as-2-years-before-my-diagnosis-and-early-as-childhood-i-am-almost-finished-with-a-survey-i-spent-10-years-as-education-director-for-
October 15, 2010 - no
If yes, explain the specific technologies, devices, drugs, or interventions you would like to
-
effectivehealthcare.ahrq.gov/products/depression-care-distributed-networks/abstract
May 08, 2009 - Describe the patterns of use of antidepressants and combinations of other psychotropic drugs, both alone
-
effectivehealthcare.ahrq.gov/products/calcineurin-inhibitor/research
March 15, 2016 - Avoidance strategies based on de novo use of alternative immunosuppressive drugs are not widely studied
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-patients-with-insomnia-how-do-commonly-used-medications-compare-for-effectiveness-and-harms-including-addictive-potential
September 22, 2010 - yes
If yes, explain the specific technologies, devices, drugs, or interventions you would like to
-
effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … Cambridge
(MA): Aegerion Pharmaceuticals, Inc.; 2012 Dec.
12 p. … Cambridge (MA):
Aegerion Pharmaceuticals, Inc.; 2013 Apr. 12 p.
-
effectivehealthcare.ahrq.gov/products/diabetes-glucose-control/research
August 04, 2010 - Exenatide, manufactured as Byetta by Amylin Pharmaceuticals, Inc. … Additionally, a separate, linkable file is available which includes pharmacy claims for prescription drugs … In Table 3 , we provide details about the other drugs for DM used by these patients. … Experts weigh in on promotion, prescription of off-label drugs. JAMA 2007;297:683-684.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/multinational-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - focused on the outcomes, effectiveness, comparative clinical
effectiveness, and appropriateness of pharmaceuticals … Food and Drug Administration [FDA], Health
Canada, Japanese Pharmaceuticals and Medical Devices Agency … http://www.fda.gov/downloads/Drugs/Drug
Safety/ucm089809.pdf. Accessed January
10, 2017.
21. … http://www.fda.gov/downloads/Drugs/Guida
nces/ucm073122.pdf. Accessed January 10,
2017.
37. … /downloads/Drugs/DrugSafety/ucm089809.pdf
http://www.wma.net/en/30publications/10policies/b3/
http://
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/multinational-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - focused on the outcomes, effectiveness, comparative clinical
effectiveness, and appropriateness of pharmaceuticals … Food and Drug Administration [FDA], Health
Canada, Japanese Pharmaceuticals and Medical Devices Agency … http://www.fda.gov/downloads/Drugs/Drug
Safety/ucm089809.pdf. Accessed January
10, 2017.
21. … http://www.fda.gov/downloads/Drugs/Guida
nces/ucm073122.pdf. Accessed January 10,
2017.
37. … /downloads/Drugs/DrugSafety/ucm089809.pdf
http://www.wma.net/en/30publications/10policies/b3/
http://
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - most regulatory approvals, and the source of most advertising and other claims made on
behalf of drugs … For example,
a systematic review of nonsteroidal anti-inflammatory drugs (NSAIDs) found cyclo-oxygenase … Do selective
cyclo-oxygenase-2 inhibitors and traditional
non-steroidal anti-inflammatory drugs … Gastrointestinal toxicity with celecoxib vs
nonsteroidal anti-inflammatory drugs for
osteoarthritis … Causality assessment
of adverse reactions to drugs—I.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - most regulatory approvals, and the source of most advertising and other claims made on
behalf of drugs … For example,
a systematic review of nonsteroidal anti-inflammatory drugs (NSAIDs) found cyclo-oxygenase … Do selective
cyclo-oxygenase-2 inhibitors and traditional
non-steroidal anti-inflammatory drugs … Gastrointestinal toxicity with celecoxib vs
nonsteroidal anti-inflammatory drugs for
osteoarthritis … Causality assessment
of adverse reactions to drugs—I.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-199-skin-cancer.pdf
December 01, 2017 - • Recurrence rates for SCC in
situ were lower with PDT and
cryotherapy than with drugs. … Adverse Events, All BCC Lesions
In Table B drugs were most likely to have adverse events
leading to … Conversely, use of topical drugs is
generally limited to primary, superficial tumors. … Therefore,
comparisons of the efficacy of radiation and drugs for the
low-risk BCCs included in our … Adjuvant radiotherapy and new drugs (including epidermal
growth factor receptor inhibitors, such as
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
July 06, 2015 - Antihypertensive drugs and risk of cancer: network
meta-analyses and trial sequential analyses of 324 … The primary goal of this review is to identify any missing studies, drugs, interventions, or
devices … is needed to determine if ACE inhibitors or ARBs offer
additional benefits over other vasoactive drugs … Since ONTARGET
directly compared the same drugs as were evaluated in
the placebo-controlled HOPE and … Since ONTARGET
directly compared the same drugs as
were evaluated in the placebo-
controlled HOPE and
-
effectivehealthcare.ahrq.gov/products/calcineurin-inhibitor/research-protocol
October 14, 2014 - amount of drug administered early or late post-transplant; 4) CNI avoidance, which substitutes other drugs … Safety of immunosuppressive drugs used as maintenance therapy in kidney transplantation: a systematic … Pharmaceuticals. 2013;6(10):1170-94. Also available: https://dx.doi.org/10.3390/ph6101170 . … relies on antibodies binding to specific antigens; frequently used to measure levels of therapeutic drugs … in a biologic sample
Nephrotoxicity: exposure of the kidneys to poisonous (toxic) chemicals; many drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
January 01, 2007 - Both
drugs are produced by the same manufacturer,
which funded all available studies. … The second-
generation antidepressants cannot be considered
identical drugs. … Evidence of moderate strength supports
some differences among individual drugs with respect
to onset … The
incidence was 8-percent (95-percent CI, 3-11
percent) higher than with comparator drugs. … Mirtazapine led to higher weight gains than
comparator drugs (fluoxetine, paroxetine,
venlafaxine, and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
February 01, 2013 - What is the effectiveness of approved RLS drugs on patient subgroups such as children,
older adults … O
2 What is the effectiveness of other drugs that are not dopamine agonists or alpha 2 ligands (e.g. … Comparator Nontreatment, drugs, or
nondrug therapies. … Nontreatment, drugs, or nondrug
therapies. … • What is the effectiveness of other drugs that are not dopamine agonists or alpha 2 ligands
(e.g.