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Showing results for "drugs".

301. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
     January 01, 2009 - Background—In drug development, a four-phase hierarchical model for the clinical evaluation of new pharmaceuticals … Analogous to the four-phase model for the evaluation of new drugs, these models require that certain … Why have the phases in the clinical evaluation of drugs become so well engrained in our thinking, and … The four phases in the development of drugs and devices have shown their merit. … Trials in humans take place only after drugs have been tested thoroughly in the laboratory in animal

302. Topic Suggestion Description | Effective Health Care Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/fibromyalgia-very-few-doctors-know-how-to-treat-this-pain-some-states-there-are-really-none-more-more-are-being-diagnosed-but-no-treatment-especially-with-severe-pain-fibro-brings-on-ibs-migrainesno-sleep-ect-a-lot-of-meds-ha
     November 01, 2011 - no If yes, explain the specific technologies, devices, drugs, or interventions you would like to

303. Iron-Deficiency Anemia in Renal Dialysis Patients | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/iron-deficiency-anemia-in-renal-dialysis-patients
     June 17, 2008 - None If yes, explain the specific technologies, devices, drugs, or interventions you would like to

304. Can anything be done to improve diabetic periphheral neuropathy?What is truly effective? What research seems promising? (diabetes type 2,well controlled) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/can-anything-be-done-to-improve-diabetic-periphheral-neuropathywhat-is-truly-effective-what-research-seems-promising-diabetes-type-2well-controlled
     April 02, 2013 - no If yes, explain the specific technologies, devices, drugs, or interventions you would like to

305. Femur Neck | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/femur-neck
     April 12, 2018 - Long-Term Drug Therapy and Drug Holidays for Osteoporotic Fracture Prevention Research Protocol April 12, 2018 Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review Systematic Review April 23, 2019

306. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
     January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Tofacitinib (CP-690,550) in combination with traditional disease-modifying anti- rheumatic drugs:

307. Quality of Life | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/quality-life
     August 08, 2018 - Synthesizing Evidence for Quality Improvement Abstract August 8, 2018 Long-Term Drug Therapy and Drug Holidays for Osteoporotic Fracture Prevention Research Protocol April 12, 2018 Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic…

308. VU EPC DBD Protocol_AHRQ comments_revised_clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf
     January 30, 2014 - CNS Drugs. 2006;20(7):549-65. PMID: 16800715 41. Newcorn JH, Ivanov I. … BTA Pharmaceuticals Inc., Bridgewater, NJ Bupropion Mylan Pharmaceuticals Inc., Morgantown, WV Selective … New York, NY Citalopram Teva Pharmaceuticals, Sellersville, PA Escitalopram Teva Pharmaceuticals, Sellersville … , PA Paroxetine Teva Pharmaceuticals, Sellersville, PA Fluvoxamine Mylan Pharmaceuticals Inc., Morgantown … ") OR SU.EXACT.EXPLODE("Adrenergic Drugs")) OR (SU.EXACT.EXPLODE("Anticonvulsive Drugs") OR SU.EXACT.EXPLODE

309. Executive Summary_Comparative Effectiveness Review No. 263: Management of Postpartum Hypertensive Disorders of Pregnancy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
     May 01, 2023 - Two RCTs specifically evaluated end-organ protective effects of two antihypertensive drugs in patients … Because the studies evaluated a large variety of specific drugs and evaluated disparate outcomes, we … evidence related to maternal morbidity and mortality (among two small studies that evaluated different drugs … Trials are needed for the numerous antihypertensive drugs commonly used in practice to allow better

310. Topic Brief on Mental Health Treatments in Pregnancy (pdf file)
     effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-disposition-mental-health-pregnancy_0.pdf
     June 01, 2021 - CNS drugs. 2017;31(6):439-450. 11. Pacchiarotti I, Leon-Caballero J, Murru A, et al. … First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies … Detoxification from opiate drugs during pregnancy. … Atypical antipsychotic drugs and pregnancy outcome: a prospective, cohort study. … Drugs. 2017;77(11):1211-1219. 56. Knickmeyer RC, Meltzer-Brody S, Woolson S, et al.

311. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-disposition-120104.pdf
     April 01, 2011 - Drugs that are not approved by the FDA have been removed. … Drugs that are not approved by the FDA have been removed. … Weiglein; Takeda Pharmaceuticals North America, Inc Results 1. … Weiglein; Takeda Pharmaceuticals North America, Inc Results 1. … Weiglein; Takeda Pharmaceuticals North America, Inc Discussion 1.

312. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1306.pdf
     October 01, 2014 - In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … after administration.35 Manufacturer and regulatory status: The drug was launched in 1966 by King Pharmaceuticals … Drugs Future. 2009;34(3):217-21. 31. Research suggests new drug targets for depression. … In: Drugs@FDA [internet]. Silver Spring (MD): U.S.

313. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/infectiousdisease_hi_impact.pdf
     December 01, 2013 - Telaprevir Telaprevir (Incivek™, Vertex Pharmaceuticals, Inc., Cambridge, MA) is orally administered … Optimer Pharmaceuticals announced a 2-year agreement with Cubist Pharmaceuticals, Inc. … Tibotec Pharmaceuticals, Vertex Pharmaceuticals. … Berlin: Vertex Pharmaceuticals; 2011 Mar 31 [accessed 2011 May 17]. [4 p]. … (FDA briefing document for Anti-Infective Drugs Advisory committee meeting).

314. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1406.pdf
     January 01, 2020 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Along with access to relatively inexpensive illicit opioid drugs, such as heroin, and increased use … Available: http://www.accessdata.fda.gov/scripts/cder/drugs atfda/index.cfm? … For drugs that save lives, a steep cost. [internet].

315. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
     January 01, 2006 - Common oral medications for osteoarthritis include nonsteroidal antiinflammatory drugs (NSAIDs) and acetaminophen … Food and Drug Administration (FDA) as pharmaceuticals, including glucosamine and chondroitin, as well … In addition, efficacy and safety may vary for individual drugs within a class. … For this report, we defined the terms “selective NSAIDs” or “COX-2 selective NSAIDs” as drugs in the … We defined “partially selective NSAIDs” as other drugs shown to have partial in vitro COX-2 selectivity

316. Adaptation of Data Mining Algorithms Assessing the Comparative Effectiveness and Safety of NSAIDs | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/nsaids-safety-data-mining/research
     December 02, 2009 - who were exposed to cyclooxygenase selective (coxib) or nonselective nonsteroidal anti-inflammatory drugs

317. Finding Evidence for Comparing Medical Interventions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-finding-evidence_methods.pdf
     January 01, 2011 - These approval documents—which can be found at Drugs@FDA.gov—may help identify publication bias even … Ottawa: Canadian Agency for Drugs and Technologies in Health; 2008. 46. … Ottawa: Canadian Agency for Drugs and Technologies in Health. … an pharmaceuticals, more non-U.S. coverage than MEDLINE Avenell, 2001 Minozzi, 2000 Sampson, … and pharmaceuticals Fishman, 1996 Wolfe, 2002 MANTIS (Manual Alternative and Natural Therapy Index

318. A Pilot Study Using Machine Learning and Domain Knowledge To Facilitate Comparative Effectiveness Review Updating | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/machine-learning/research
     September 07, 2012 - decisions from a 2006 comparative effectiveness review of off-label uses of atypical anti-psychotic drugs

319. Impact of Employment Interventions for Persons with Serious Mental Illnesses (SMI) on Non-Employment Patient-Centered Outcomes | Effective Health Care Program
     effectivehealthcare.ahrq.gov/products/mental-illness-employment/abstract
     December 20, 2011 - patterns of medical and mental health care and patient-reported functional status, use of alcohol and drugs

320. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0407_01-20-2011.pdf
     January 01, 2011 - PICO Population(s): Adult patients with PAD and comorbid or multimorbid disease Intervention(s): Drugs