-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - and telaprevir (trade name
Incivek®), for treatment of chronic HCV genotype
1 infection.24,25 Both drugs … Packets on unpublished
and published trials were solicited from manufacturers of
included antiviral drugs … their
effects would be helpful for guiding health care providers’
treatment choices between these drugs … Third, few trials
have evaluated the regimens approved specifically by the
FDA for these drugs, limiting … are currently in active development,
and further studies with new drugs and drug regimens are
expected
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
February 01, 2015 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … targeting pathways and processes hypothesized to underlie AD-related cognitive decline,
neuroprotective pharmaceuticals … CNS Drugs. 2013 Jul;27(7):505-14.
-
effectivehealthcare.ahrq.gov/products/osteoporosis-fracture-prevention/research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-adults-prisons_research-protocol.pdf
September 13, 2012 - lower risk for developing movement disorders and
other unpleasant side effects, but some of these drugs … in most prison formularies for treating bipolar disorder and
schizoaffective disorder because these drugs … Drug therapy/
Exp antidepressive agents/
Psychotropic drugs/
Therapeutic use.fs. … OR exp neuroleptic
agent/ OR exp neuroleptic drugs/ OR psychopharmacotherapy/ OR psychotropic
agent … / OR psychotropic drugs/
8 Pharmacologic
interventions
Text words
(drug ADJ (based OR counseling
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-evidence-reviews-federal-agencies.pdf
July 01, 2020 - These reviews focus on a variety of issues,
including comparing clinical drugs or treatments, and interventions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
November 01, 2014 - hospital-acquired pneumonia.
4
Optimal treatment involves choosing the right drug
or combination of drugs … During the same period, the number of new antibiotics
developed has decreased, especially for drugs … toxicities.19 With fewer
antibiotic options, ensuring the appropriate and judicious
use of these drugs … infection
more rapidly and accurately, public policies to support
development and approval of new drugs … Bad bugs, no drugs: no ESCAPE revisited. Clin
Infect Dis. 2009 Sep 15;49(6):992-3.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-update_research-protocol.pdf
January 15, 2015 - The antihypertensive agents, lipid-lowering
drugs, and antiplatelet agents are all FDA approved for … The risks and adverse events of the
drugs are well-understood and include symptomatic hypotension, myalgia … therapy, including “aggressive medical therapy” (antihypertensive,
antiplatelet, and lipid-lowering drugs … Categorical (eg, better/worse)
o Continuous BP
o Medication need (eg, number of antihypertensive drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
July 01, 2016 - Treatments typically follow a progression from less invasive
nonsurgical interventions (dietary fiber, drugs … Nonsurgical treatments include dietary fiber supplementation,
bowel schedules, stool-modifying drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/s1.pdf
October 01, 2007 - health of many Americans as well as the effectiveness of nearly all other health care
services in which pharmaceuticals … As the federal government becomes a major payer
of prescription drugs while also providing insurance
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-3-nonopioid-pharm-chronic-pain.pdf
July 01, 2022 - Pregabalin/
gabapentin versus
duloxetine short-
term
No difference between drugs
• SOE: Insufficient … 83
Conclusions
A systematic review and three subsequent surveillance updates have found nonopioid drugs … Nonopioid drugs were associated with increased risk of class-specific
harms (e.g., gastrointestinal … vivo
effects of nonselective, partially selective,
and selective non steroidal anti-
inflammatory drugs … Effectiveness and safety of non-steroidal
anti-inflammatory drugs and opioid
treatment for knee and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
September 01, 2019 - Key Messages
• As initial therapy in the prehospital setting:
– Nonsteroidal anti-inflammatory drugs … including ketamine,
acetaminophen (APAP), nitrous
oxide/oxygen and nonsteroidal
anti-inflammatory drugs … Versus Opioid
Opioids Versus
APAP
Opioids
Versus Nitrous
Oxide
Opioids Versus
NSAIDs
Specific drugs … =intranasal;
IV=intravenous; NEB=nebulized; NR=not reported; NSAIDs=nonsteroidal anti-inflammatory drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
January 01, 2015 - other drugs). … We made a note
of this in Table 2, where the drugs are first
described. … Provide the names of the
specific drugs, as in Table 51 on the next page. … Same issue, provide the names of specific
drugs. … Incretinbased drugs and
the risk of congestive heart failure.
-
effectivehealthcare.ahrq.gov/products/grant-manuscripts/rapid-network-abstract
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
December 16, 2011 - Pharmacological treatment is generally reserved for patients with severe RLS.
11
The major classes
of drugs … nicotine; antidepressants; antihistamines)
†Adverse effects of treatments are specific to use of these drugs … We do not know the impact of long-term use of
these drugs in children. … Neither do we know the risks/benefits of the drugs for older adults who
take several medications for … All reported adverse reactions and effects including Augmentation (Harms
specific to each class of drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
March 01, 2013 - Pomona, NY: Duramed
Pharmaceuticals, Inc.; 2009.
83. Nordette [package insert]. … Wayne, NJ: Bayer HealthCare
Pharmaceuticals, Inc.; 2012.
86. … Wayne, NJ: Bayer HealthCare
Pharmaceuticals, Inc.; 2009.
92. FDA. … Morgantown, WV:
Mylan Pharmaceuticals, Inc.; 2006.
106. Naprosyn [package insert]. … Nonsteroidal anti-
inflammatory drugs for dysmenorrhoea.
-
effectivehealthcare.ahrq.gov/sites/default/files/introduction-user-guide-to-ocer_130129.pdf
April 26, 2012 - In addition, new drugs and other interventions
often lack comparative efficacy data to quantify
a therapy … obstructive
pulmonary disease,13 carotid revascularization
among Medicare beneficiaries,14 prescription
drugs … ADHD
drugs and serious cardiovascular events in
children and young adults.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-psoriatric_research-protocol.pdf
December 06, 2010 - Available therapies
for PsA include corticosteroids, oral disease-modifying antirheumatic drugs (DMARDs … Finally, very little is known about the benefits or risks of these
drugs in different patient subgroups … Simponi®
Tocililizumab Actemra®, RoActemrai®
• Comparators:
All key questions: all review drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
December 01, 2014 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Available:
http://www.cesar.umd.edu/cesar/drugs/ketamine.
pdf.
4. … CNS Drugs. 2012 Mar
1;26(3):189-204. … PMID: 23200737
http://www.cesar.umd.edu/cesar/drugs/ketamine.pdf
http://www.cesar.umd.edu/cesar/drugs … Rochester (MI): JHP
Pharmaceuticals, LLC; 2011 Jun. 4 p.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0651-131114.pdf
June 20, 2013 - joint steroid injection,
intradiscal methylene blue, intradiscal ozone, injections involving anti-TNF drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - focused on the outcomes, effectiveness, comparative clinical effectiveness, and
appropriateness of pharmaceuticals … evaluate
outcomes for diverse purposes ranging from the
natural history of a disease, to the safety of drugs … focused on the outcomes,
effectiveness, comparative clinical effectiveness, and
appropriateness of pharmaceuticals … AEs are categorized according to the
seriousness and, for drugs, the expectedness of the
event. … If the
registry receives sponsorship, in whole or in part,
from a regulated industry (for drugs or devices