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  1. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1406.pdf
    January 01, 2020 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Along with access to relatively inexpensive illicit opioid drugs, such as heroin, and increased use … Available: http://www.accessdata.fda.gov/scripts/cder/drugs atfda/index.cfm? … For drugs that save lives, a steep cost. [internet].
  2. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
    January 01, 2016 - San Diego (CA): Amylin Pharmaceuticals, Inc.; 2010 Jun 15 [accessed 2011 Feb 22]. [3 p]. … Amylin Pharmaceuticals. … San Diego (CA): Amylin Pharmaceuticals, Inc.; 2012 Jan 27 [accessed 2012 Feb 20]. [4 p]. … San Diego (CA): Amylin Pharmaceuticals, Inc.; 2012 Jan 27. 11 p. … Get drugs straight to the eye. [internet].
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
    January 27, 2012 - The following designs were also eligible for KQ 3 if they compared two or more drugs of interest: nonrandomized … cohort studies, and case-control studies were eligible as long as the studies compared two or more drugs … J Stud Alcohol Drugs. 2008 Jul;69(4):535-8. PMID: 18612569. 19. … J Stud Alcohol Drugs. 2009 Mar;70(2):186-96. PMID: 19261230. 47. … Chronic care management for dependence on alcohol and other drugs: the AHEAD randomized trial.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0075_03-10-2009.pdf
    January 01, 2009 - corticosteroids, immune system suppressors, antibiotics, anti-diarrheals, anti-tumor necrosis factor (TNF) drugs
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0313_02-09-2009.pdf
    January 01, 2009 - A number of drugs and dietary measures have been shown to reduce the rate of stone recurrence.
  6. S16 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
    October 01, 2007 - controlled trials (RCTs) remain the ac- cepted “gold standard” for determining the efficacy of new drugs … Follow-up and monitoring is designed to promote adherence to the drugs under study and to detect any … Drug coverage—Which bisphosphonate drugs should be included on a drug fomulary? … , quality of intervention Timing of intervention Cointerventions, quality of care Adherence (for drugs … Treatment with drugs to lower blood pressure and blood cholesterol based on an individual’s absolute
  7. S89 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
    October 01, 2007 - Rapid Cycle Analysis Team Background: Rare but serious adverse events associated with vac- cines or drugs … meningococcal vaccine, drug safety (Med Care 2007;45: S89–S95) Concerns about the safety of vaccines and drugs … the Centers for Disease Control and Prevention (CDC) and Food and Drug Administration (FDA) and, for drugs … In addition, because drugs treat specific conditions, the pool of users for a new medication is limited … early detection of potential adverse events after the introduction of new vaccines, and possibly new drugs
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
    December 06, 2010 - Available therapies for RA include corticosteroids, oral disease-modifying antirheumatic drugs (DMARDs … Finally, very little is known about the benefits or risks of these drugs AMONG different patient subgroups … review did not include certolizumab pegol, golimumab, and tocilizumab (listed above), because these drugs … Golimumab Simponi® Tocililizumab Actemra®, RoActemrai® • Comparators: For all KQs: all review drugs
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
    August 01, 2017 - Food and Drug Administration (FDA) has approved several prescription drugs for insomnia, typically … Food and Drug Administration (FDA) for insomnia. d Other benzodiazepines include drugs approved by … the FDA for insomnia (estazolam, flurazepam, lorazepam, quazepam, and triazolam) and drugs not approved
  10. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
    May 01, 2006 - trials comparing darbepoetin to epoetin showed no statistically significant difference between these drugs … trials comparing darbepoetin to epoetin showed no statistically significant difference between these drugs … trials comparing darbepoetin to epoetin showed no statistically significant difference between these drugs
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
    January 27, 2012 - prevention or pharmacotherapy combined with various co-interventions (including both FDA-approved drugs … Inpatient settings Interventions As defined above in PICOTS Pharmacotherapy for alcohol withdrawal; any drugs … J Stud Alcohol Drugs. 2008 Jul;69(4):535-8. PMID: 18612569. 23.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
    January 09, 2020 - However, simple analgesics including 2 nonsteroidal anti-inflammatory drugs (NSAIDs) used … reason, the American Headache Society has explicitly stated that opioids and butalbital-containing drugs … therapy versus: 1) nonopioid pharmacologic therapy (e.g., acetaminophen, nonsteroidal anti-inflammatory drugs … effectiveness of nonopioid pharmacologic therapy (e.g., acetaminophen, nonsteroidal anti-inflammatory drugs … , topical nonopioid abortive drug, including: • Acetaminophen • Nonsteroidal anti-inflammatory drugs
  13. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1412.pdf
    January 01, 2015 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Results The table below lists the four topics for which (1) preliminary phase III data for drugs, at … San Diego (CA): Amylin Pharmaceuticals, Inc.; 2012 Jan 27 [accessed 2014 Apr 10]. [5 p]. … Get drugs straight to the eye. [internet].
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0108_05-24-2009.pdf
    January 01, 2009 - migraine patients require multiple doses and often do not relieve the migraine and that some other drugs
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-199-skin-cancer.pdf
    December 01, 2017 - • Recurrence rates for SCC in situ were lower with PDT and cryotherapy than with drugs. … Adverse Events, All BCC Lesions In Table B drugs were most likely to have adverse events leading to … Conversely, use of topical drugs is generally limited to primary, superficial tumors. … Therefore, comparisons of the efficacy of radiation and drugs for the low-risk BCCs included in our … Adjuvant radiotherapy and new drugs (including epidermal growth factor receptor inhibitors, such as
  16. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
    July 06, 2015 - Antihypertensive drugs and risk of cancer: network meta-analyses and trial sequential analyses of 324 … The primary goal of this review is to identify any missing studies, drugs, interventions, or devices … is needed to determine if ACE inhibitors or ARBs offer additional benefits over other vasoactive drugs … Since ONTARGET directly compared the same drugs as were evaluated in the placebo-controlled HOPE and … Since ONTARGET directly compared the same drugs as were evaluated in the placebo- controlled HOPE and
  17. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
    January 01, 2007 - Both drugs are produced by the same manufacturer, which funded all available studies. … The second- generation antidepressants cannot be considered identical drugs. … Evidence of moderate strength supports some differences among individual drugs with respect to onset … The incidence was 8-percent (95-percent CI, 3-11 percent) higher than with comparator drugs. … Mirtazapine led to higher weight gains than comparator drugs (fluoxetine, paroxetine, venlafaxine, and
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_surveillance.pdf
    March 14, 2013 - CER # 28: Disease-Modifying Antirheumatic Drugs (DMARDs) in Children with Juvenile Idiopathic Arthritis … ..................................................... 5 1 Disease-Modifying Antirheumatic Drugs … Introduction Comparative Effectiveness Review (CER) #28, Disease-Modifying Antirheumatic Drugs … examples of how advances in understanding the biology of inflammation have led to development of drugs … Disease-Modifying Antirheumatic Drugs (DMARDs) in Children with Juvenile Idiopathic Arthritis (JIA)
  19. 8 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
    November 01, 2008 - most regulatory approvals, and the source of most advertising and other claims made on behalf of drugs … For example, a systematic review of nonsteroidal anti-inflammatory drugs (NSAIDs) found cyclo-oxygenase … Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs … Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis … Causality assessment of adverse reactions to drugs—I.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_surveillance.pdf
    March 14, 2013 - CER # 28: Disease-Modifying Antirheumatic Drugs (DMARDs) in Children with Juvenile Idiopathic Arthritis … ..................................................... 5 1 Disease-Modifying Antirheumatic Drugs … Introduction Comparative Effectiveness Review (CER) #28, Disease-Modifying Antirheumatic Drugs … examples of how advances in understanding the biology of inflammation have led to development of drugs … Disease-Modifying Antirheumatic Drugs (DMARDs) in Children with Juvenile Idiopathic Arthritis (JIA)

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