-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
January 27, 2012 - prevention or pharmacotherapy combined with
various co-interventions (including both FDA-approved drugs … Inpatient settings
Interventions As defined above in PICOTS Pharmacotherapy for alcohol
withdrawal; any drugs … J Stud Alcohol Drugs.
2008 Jul;69(4):535-8. PMID: 18612569.
23.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_disposition-comments.pdf
August 23, 2013 - Public Reviewer
#1 – Sabine
Luik, Boehringer
Ingelheim
Pharmaceuticals,
Inc. … Public Reviewer
#1 – Sabine
Luik, Boehringer
Ingelheim
Pharmaceuticals,
Inc. … Public Reviewer
#1 – Sabine
Luik, Boehringer
Ingelheim
Pharmaceuticals,
Inc. … Acknowledged
Public Reviewer
#1 – Sabine
Luik, Boehringer
Ingelheim
Pharmaceuticals,
Inc. … No known reversibility agents for the new
drugs.
Thank you for this comment.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0075_03-10-2009.pdf
January 01, 2009 - corticosteroids, immune system suppressors,
antibiotics, anti-diarrheals, anti-tumor necrosis factor (TNF) drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0313_02-09-2009.pdf
January 01, 2009 - A number of drugs and dietary measures have been shown to reduce the rate of stone
recurrence.
-
effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
October 01, 2007 - controlled trials (RCTs) remain the ac-
cepted “gold standard” for determining the efficacy of new drugs … Follow-up and monitoring is
designed to promote adherence to the drugs under study and
to detect any … Drug coverage—Which bisphosphonate drugs should be included on a
drug fomulary? … , quality of intervention
Timing of intervention
Cointerventions, quality of care
Adherence (for drugs … Treatment with drugs to lower
blood pressure and blood cholesterol based on an individual’s absolute
-
effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
October 01, 2007 - Rapid Cycle
Analysis Team
Background: Rare but serious adverse events associated with vac-
cines or drugs … meningococcal vaccine, drug safety
(Med Care 2007;45: S89–S95)
Concerns about the safety of vaccines and drugs … the
Centers for Disease Control and Prevention (CDC) and Food
and Drug Administration (FDA) and, for drugs … In addition, because drugs treat specific conditions, the pool
of users for a new medication is limited … early detection of potential adverse events after the
introduction of new vaccines, and possibly new drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
December 06, 2010 - Available therapies for RA include
corticosteroids, oral disease-modifying antirheumatic drugs (DMARDs … Finally, very little is known about the
benefits or risks of these drugs AMONG different patient subgroups … review did not include certolizumab pegol, golimumab,
and tocilizumab (listed above), because these drugs … Golimumab Simponi®
Tocililizumab Actemra®, RoActemrai®
• Comparators:
For all KQs: all review drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
August 01, 2017 - Food and Drug Administration (FDA) has
approved several prescription drugs for insomnia, typically … Food and Drug Administration
(FDA) for insomnia.
d Other benzodiazepines include drugs approved by … the FDA for insomnia (estazolam, flurazepam, lorazepam, quazepam, and triazolam) and drugs
not approved
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
May 01, 2006 - trials
comparing darbepoetin to epoetin showed no
statistically significant difference between these
drugs … trials comparing
darbepoetin to epoetin showed no statistically
significant difference between these drugs … trials comparing
darbepoetin to epoetin showed no statistically
significant difference between these drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0108_05-24-2009.pdf
January 01, 2009 - migraine patients require multiple
doses and often do not relieve the migraine and that some other drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-199-skin-cancer.pdf
December 01, 2017 - • Recurrence rates for SCC in
situ were lower with PDT and
cryotherapy than with drugs. … Adverse Events, All BCC Lesions
In Table B drugs were most likely to have adverse events
leading to … Conversely, use of topical drugs is
generally limited to primary, superficial tumors. … Therefore,
comparisons of the efficacy of radiation and drugs for the
low-risk BCCs included in our … Adjuvant radiotherapy and new drugs (including epidermal
growth factor receptor inhibitors, such as
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
July 06, 2015 - Antihypertensive drugs and risk of cancer: network
meta-analyses and trial sequential analyses of 324 … The primary goal of this review is to identify any missing studies, drugs, interventions, or
devices … is needed to determine if ACE inhibitors or ARBs offer
additional benefits over other vasoactive drugs … Since ONTARGET
directly compared the same drugs as were evaluated in
the placebo-controlled HOPE and … Since ONTARGET
directly compared the same drugs as
were evaluated in the placebo-
controlled HOPE and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
January 01, 2007 - Both
drugs are produced by the same manufacturer,
which funded all available studies. … The second-
generation antidepressants cannot be considered
identical drugs. … Evidence of moderate strength supports
some differences among individual drugs with respect
to onset … The
incidence was 8-percent (95-percent CI, 3-11
percent) higher than with comparator drugs. … Mirtazapine led to higher weight gains than
comparator drugs (fluoxetine, paroxetine,
venlafaxine, and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
November 27, 2012 - We understand that many drugs have different
mechanisms of action (e.g., an antiemetic can
have analgesic … Promethazine (Phenergan) was included in
Table 1 under the “other agents” portion as
one of the drugs … Peer Reviewer
#2
Executive summary In the Executive Summary, drugs are loosely discussed in terms … of
neuroleptics, metoclopramide, and antihistamines (without specific
drugs listed), while in the … We collectively referred to these drugs as
“orphan agents”.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - most regulatory approvals, and the source of most advertising and other claims made on
behalf of drugs … For example,
a systematic review of nonsteroidal anti-inflammatory drugs (NSAIDs) found cyclo-oxygenase … Do selective
cyclo-oxygenase-2 inhibitors and traditional
non-steroidal anti-inflammatory drugs … Gastrointestinal toxicity with celecoxib vs
nonsteroidal anti-inflammatory drugs for
osteoarthritis … Causality assessment
of adverse reactions to drugs—I.
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - most regulatory approvals, and the source of most advertising and other claims made on
behalf of drugs … For example,
a systematic review of nonsteroidal anti-inflammatory drugs (NSAIDs) found cyclo-oxygenase … Do selective
cyclo-oxygenase-2 inhibitors and traditional
non-steroidal anti-inflammatory drugs … Gastrointestinal toxicity with celecoxib vs
nonsteroidal anti-inflammatory drugs for
osteoarthritis … Causality assessment
of adverse reactions to drugs—I.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_surveillance.pdf
March 14, 2013 - CER # 28:
Disease-Modifying Antirheumatic Drugs (DMARDs) in
Children with Juvenile Idiopathic Arthritis … ..................................................... 5
1
Disease-Modifying Antirheumatic Drugs … Introduction
Comparative Effectiveness Review (CER) #28, Disease-Modifying Antirheumatic Drugs … examples of how advances in understanding the biology of inflammation have led to
development of drugs … Disease-Modifying Antirheumatic Drugs
(DMARDs) in Children with Juvenile
Idiopathic Arthritis (JIA)
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_surveillance.pdf
March 14, 2013 - CER # 28:
Disease-Modifying Antirheumatic Drugs (DMARDs) in
Children with Juvenile Idiopathic Arthritis … ..................................................... 5
1
Disease-Modifying Antirheumatic Drugs … Introduction
Comparative Effectiveness Review (CER) #28, Disease-Modifying Antirheumatic Drugs … examples of how advances in understanding the biology of inflammation have led to
development of drugs … Disease-Modifying Antirheumatic Drugs
(DMARDs) in Children with Juvenile
Idiopathic Arthritis (JIA)
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - have also emerged since 2010 which may change the balance of benefit
and risk attributable to these drugs … In this era of
intensive direct-to-consumer marketing of new drugs, clinicians need a trustworthy source … Health and Human Services; 2008 [cited 2014 July
13]; Available from:
http://www.fda.gov/downloads/Drugs … Comparative
effectiveness and safety of medications for type 2 diabetes: an update including new drugs … http:www.effectivehealthcare.ahrq.gov
http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
January 01, 2011 - For example, the individual trials of statin drugs to treat high
cholesterol each selected specific … and discrete populations, used different drugs, different
dosages, and different cointerventions. … differing risks,
nationalities, and underlying conditions provides evidence that the benefits of statin drugs … Drugs
2007;67(14):1969-1979.
20. Walker, CF, Kordas K, Stoltzfus, RJ, et al. … Drug class review of Alzheimer’s drugs.
Final report. 2006.