-
effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
October 01, 2007 - Of 10,383
reports in 2004, 100% listed patient age, sex, and disposition; 98%
listed the implicated drugs … provides detailed and timely infor-
mation on outpatient ADEs treated in EDs and identifies specific
drugs … Deiden-
tified data are then forwarded to CDC where all case reports
involving pharmaceutical products … drugs are suspected, this
information may be added as a free-text description. … Risk assessment of drugs, biologics and therapeutic devices: present and
future issues.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
March 01, 2013 - Trospium chloride 60
mg once daily
Placebo Esprit Pharma and
Indevus
Pharmaceuticals Inc. … (formerly Indevus
Pharmaceuticals Inc.). … Oxybutynin 2.5 mg
twice daily
Placebo Funded by Smith and
Nephew
Pharmaceuticals Ltd. … chloride Propantheline and
placebo
Pharmcia Leo
Therapeutics,
Helsingborg, Sweden
provided the
pharmaceutical … preparations used in
this study
Toglia, 201075
Study: Post-hoc Karram,
200939
VENUS
N: 739
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
April 18, 2013 - We did
review off-label drugs available in the US. … of the outcomes with different
drugs. … The large number of off label drugs may
reflects the fact that approved drugs have
undesirable balance … drugs
from different classes. … , as well as individual drugs.
-
effectivehealthcare.ahrq.gov/sites/default/files/s5.pdf
October 01, 2007 - The
advent of Medicare Part D for outpatient prescription drugs has
drawn significant attention to the … or outcome misclassification), random er-
ror, confounding by clinical conditions, indications for drugs … , both alone and in comparison across
drugs. … Assessment of adherence
to and persistence on disease-modifying antirheumatic drugs
(DMARDs) in patients … Comparison of meta-
analytic results of indirect, direct, and combined comparisons of drugs
for chronic
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1506.pdf
June 01, 2015 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … Results
The table below lists the single topic for which (1) preliminary phase III data for drugs (or … Frustratingly, an
unusually high percentage of investigational drugs have not met primary endpoints
-
effectivehealthcare.ahrq.gov/products/diabetes-oral-drugs-safety-knowledge-gaps/research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
May 29, 2025 - Drugs and devices that are subject to CED should qualify for Medicare transitional pass-through status … Application of CED to on-label uses of drugs and biologicals restricts patient access. … Caution against the broad use of CED for on-label uses of drugs and biologics that have gone through … Ban CED for drugs with accelerated approval. … Recommends that on-label uses of drugs and biologicals be excluded from CED restrictions.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
January 01, 2015 - When
considering categories of these interventions, such as drugs, devices, and procedures, new
pharmaceuticals … that new pharmaceuticals/biotechnologies and new off-label uses of existing
pharmaceuticals constitute … New Era of High-Cost Pharmaceuticals
The proportion of costs attributable to new specialty pharmaceuticals … Although anti-obesity drugs are not part of the high-cost paradigm seen with specialty
pharmaceuticals … The demand for new antiobesity drugs has been addressed in large part by three new oral
drugs approved
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - Patients with osteoarthritis also use over-the-counter
supplements not regulated by the FDA as pharmaceuticals … Pharmacokinetics, Indications, and Dosing of drugs to be included. … Oral drugs (trade names provided only for drugs under patent)
Drug (any trade name): acetaminophen … Non-steroidal anti-inflammatory
drugs. … Non-steroidal anti-inflammatory
drugs for low-back pain.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
April 01, 2013 - Topiramate and propranolol decreased use of drugs for acute migraine attacks. … among approved drugs. … Approved drugs were more effective than off-label
drugs except for the angiotensin II receptor blocker … or approved versus off-label drugs. … or approved versus off label drugs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0024_06-09-2008.pdf
January 01, 2008 - manic or
depressive phases, rapid cycling, mixed states), do the typical and atypical
antipsychotic drugs … For adults experiencing a first episode of schizophrenia, do the atypical
antipsychotic drugs differ … comparative
evidence that differences in adherence or persistence among the atypical
antipsychotic drugs … developmental disorders or disruptive behavior disorders,
do the typical and atypical antipsychotic drugs … Behavioral and Psychological Symptoms of Dementia (BPSD),
do the typical and atypical antipsychotic drugs
-
effectivehealthcare.ahrq.gov/products/dietary-supplements/research
-
effectivehealthcare.ahrq.gov/sites/default/files/14_substanceabuse_potential_high_impact_june_2012.pdf
January 01, 2012 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … However, experts shared the belief that these drugs’ benefits would prove to be only incremental … Prescription drugs: abuse and addiction. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia_hi_impact.pdf
January 01, 2012 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures … interventions expected to be within 0 to 4 years of potential diffusion (e.g., in phase III trials
for pharmaceuticals … Information is compiled for expert comment on topics at a granular level (i.e., similar
drugs in the … The search is on for ways to definitively diagnose AD and for drugs, biologics, and alternative or
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
December 15, 2010 - specific dietary
supplements (when compared to cardiovascular drugs alone or cardiovascular drugs and … Classes of commonly used cardiovascular drugs to be considered (excluding drugs used
exclusively for … Analytic Framework for Dietary Supplement Use in Adults
Taking Cardiovascular Drugs. … Drugs Aging 2009;26(Suppl 1):41-51.
4. Garner JB. … Drugs 2009;69:1777-98.
7. Miller KL, Liebowitz RS, Newby LK.
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
December 01, 2014 - NPS Pharmaceuticals, Inc.. … Bedminster (NJ): NPS
Pharmaceuticals, Inc.; 2014 Jun. 18 p.
8. … Bedminster (NJ): NPS
Pharmaceuticals, Inc.; 2011 May 12 [accessed
2011 Jul 15]. [2 p]. … Bedminster (NJ): NPS Pharmaceuticals,
Inc.; 2011 Oct 31 [accessed 2011 Nov 11]. [4 p]. … Bedminster (NJ): NPS
Pharmaceuticals, Inc.; 2012 Dec 21. 45 p.
14.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_executive.pdf
June 01, 2013 - ,
pediatricians prescribe drugs approved for adults or off-
label drugs (approved for clinical conditions … Off-Label Pharmacologic Agents: Antiepileptic Drugs
Topiramate. … Two small RCTs compared drugs with active
nonpharmacologic treatments. … No studies compared combined treatments for migraine
prevention with drugs alone. … Drugs for preventing migraine headaches
in children.
-
effectivehealthcare.ahrq.gov/sites/default/files/s9.pdf
October 01, 2007 - detailed (including
beneficiary identifiers, contract identifiers pharmacy provider infor-
mation on drugs … Key Words: Medicare, Part D, pharmaceuticals
(Med Care 2007;45: S9–S12)
The Medicare Part D benefit … Part D plan covers 15%,
and the beneficiary pays a 5% coinsurance, or copayments of
$2 for generic drugs … and $5 for nongeneric drugs. … Drugs provided (including the National Drug Classifica-
tion �NDC� code, compound code, and quantity
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1506.pdf
October 01, 2015 - Boston (MA): Vertex Pharmaceuticals, Inc.; 2014
Nov 05 [accessed 2014 Dec 11]. [3 p]. … Boston (MA): Vertex
Pharmaceuticals Inc.; 2015 Jan 11 [accessed 2015
May 13]. [5 p]. … Boston (MA):
Vertex Pharmaceuticals Inc.; 2015 May 12
[accessed 2015 May 13]. [2 p]. … Boehringer Ingelheim Pharmaceuticals, Inc. … Ridgefield (CT):
Boehringer Ingelheim Pharmaceuticals, Inc.; 2014
Oct. 18 p.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
July 27, 2023 - Center Rapid Response Protocol
Project Title: Making Healthcare Safer IV:
Protocols for High-Risk Drugs … The “Protocols for High-Risk Drugs:
Reducing Adverse Drug Events Related to Anticoagulants” as a patient … High-Alert Drugs: Patient Safety Practices for
Intravenous Anticoagulants.