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  1. effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Autism treatments and drugs. [internet].
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol-amendment.pdf
    November 26, 2024 - For example, emergency department visits related to NMU of these drugs by adults increased from 5,212 … Misuse of Prescription Drugs Research Report. 2023. … https://nida.nih.gov/publications/research-reports/misuse-prescription-drugs/overview. … MMWR https://nida.nih.gov/publications/research-reports/misuse-prescription-drugs/overview https://
  3. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - Vertex Pharmaceuticals, Cystic Fibrosis Foundation. … Vertex Pharmaceuticals Incorporated, Cystic Fibrosis Foundation. … Pricing for orphan drugs: will the market bear what society cannot? … Vertex Pharmaceuticals Incorporated. … Vertex Pharmaceuticals Incorporated.
  4. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
    January 01, 2012 - In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … several weeks, following a single infusion. 37,41,42 The drug was originally launched by King PharmaceuticalsDrugs Future 2009;34(3):217-21. 39. Thomson Reuters Integrity [database online]. … In: Drugs@FDA [internet]. Silver Spring (MD): U.S. … Available: http://www.accessdata.fda.gov/scripts/cder/drugs atfda/index.cfm?
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
    November 01, 2012 - ergot derivatives (e.g., dihydroergotamine [DHE]), intravenous (IV) nonsteroidal anti-inflammatory drugs … Food and Drug Administration documents related to the drugs of interest were reviewed for additional … We recognize that many drugs have various effects. … For the mixed-treatment analysis, we identified a group of drugs that were not easily classified and … We refer to these drugs collectively as “orphan agents.”
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-protocol.pdf
    December 01, 2011 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … If so, do not select, because these are “me-too” of existing drugs. … Covers future industry trends, key industry developments, research and development of drugs and pharmaceuticals … Industries covered: pharmaceuticals, biotechnology, medical equipment & devices, and in vitro diagnostics
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
    June 28, 2013 - And for KQ4, comparing anti-arrhythmic drugs (AADs) with electrical cardioversion for restoration of … We have added additional information about whether the drugs were given IV, orally, or a combination … Mascette ES (Results) The inclusion of amiodarone and sotalol as rate-control drugs (pp. … Mascette Results A gender difference in efficacy of drugs (but not proarrhythmia) is mentioned on … Comparative efficacy of rate control drugs is a good example.
  8. effectivehealthcare.ahrq.gov/products/juvenile-arthritis-dmards/research-protocol
  9. S158 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
    October 01, 2007 - Measures: Association between nonsteroidal antiinflammatory drugs (NSAIDs) and mortality. … In addition, frail elderly patients, who use the most drugs and have the highest adverse event rates, … These databases are, however, often the best source of information on the association between drugs and … diseases, because they allow timely assessment of infrequently used drugs and rare outcomes in large … Selective prescribing led to overestimation of the benefits of lipid-lowering drugs.
  10. #05 DEPRESSION (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … Results The table below lists the seven topics for which (1) preliminary phase III data on drugs or … to several weeks, following a single infusion. 29,33,34 The drug was launched in 1966 by King PharmaceuticalsDrugs Future 2009;34(3):217-21. 31. Thomson Reuters Integrity [database online]. … In: Drugs@FDA [internet]. Silver Spring (MD): U.S.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
    August 07, 2018 - Introduction Peer Reviewer #6 “Drugs for acute mania are generally used for shorter periods than … drugs used for treating depression or for maintenance.” – This is often not the case. … The statement is not true of other drugs. Thank you for the clarification. … We revised the sentence to read that some drugs may increase these risks. … Perhaps for clarity “Other drugs for acute mania” could be relabeled “Drugs Not Approved by FDA For
  12. effectivehealthcare.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
    January 01, 2012 - Optimer Pharmaceuticals announced a 2-year agreement with Cubist Pharmaceuticals, Inc. … Tibotec Pharmaceuticals, Vertex Pharmaceuticals. … Cambridge (MA): Vertex Pharmaceuticals, Inc.; 2012 Feb 23 [accessed 2012 May 21]. [5 p]. … Cambridge (MA): Vertex Pharmaceuticals Incorporated; [accessed 2012 May 17]. [3 p]. … San Diego (CA): Optimer Pharmaceuticals, Inc.; 2011 [accessed 2011 Jul 21]. [4 p].
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/headaches-pregnancy.pdf
    March 23, 2019 - For example, nonsteroidal anti- inflammatory drugs (NSAIDs) have been shown to be associated with a higher … therapies used outside of pregnancy, such as complementary and alternative therapies and biologic drugs … Use of non-steroidal anti-inflammatory drugs in pregnancy: impact on the fetus and newborn. … https://www.fda.gov/drugs/drugsafety/ucm350684.htm. Accessed on March 23, 2019. … https://www.fda.gov/drugs/drugsafety/ucm350684.htm 19 16. Andrade C.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/point-of-care_research.pdf
    April 01, 2014 - We typically did not review evidence summaries on specific interventions, such as specific drugs or … Dietary Supplements in Adults Taking Cardiovascular Drugs. … Interactions of commonly used dietary supplements with cardiovascular drugs: a systematic review. … Dietary Supplements in Adults Taking Cardiovascular Drugs. … Interactions of commonly used dietary supplements with cardiovascular drugs: a systematic review.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
    April 01, 2012 - Available therapies for PsA include corticosteroids, oral disease-modifying antirheumatic drugs or … Effective Health Care infliximab) are also classified as antitumor necrosis factor (anti-TNF) drugs … Finally, very little is known about the benefits or risks of these drugs in different patient subgroups … Analytic framework for treatment for psoriatic arthritis DMARDS = disease-modifying antirheumatic drugs … Discussion No head-to-head controlled trials meeting inclusion criteria existed for any drugs in this
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
    November 27, 2012 - Peer Reviewer #1 Introduction The gabapentin- pregabalin group of drugs is called “GABA analogs”. … This complication can occur in 9- 17% of RLS patients using these drugs. … First, FDA approved drugs include rotigotine (probably approved after submission) and gabapentin enacarbil … was not identified as a therapy commonly used and we identified no eligible studies examining these drugs … Since most of the report does not actually compare drugs, why can these not be included?
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostatic-hyperplasia-medications_research-protocol.pdf
    April 21, 2015 - Prescribing behavior has changed with the approval of new drugs and the availability of new evidence … for efficacy, comparative effectiveness, and harms.6 Table 1 provides a list of drugs commonly used … and enlarged prostates with either agent are supported by systematic reviews.10, 13 Recently, newer drugs … A new AB, silodosin, was approved for the treatment of BPH in 2008.7 Several anticholinergics drugs … symptoms such as urgency, frequency, and nocturia, which may or may not be causally related.15 These drugs
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-heart-disease-children_research.pdf
    January 01, 2023 - The study drugs included all medications with a label indication for treatment of ADHD as of December … Study Medications ADHD medications and other drugs of interest were identified from pharmacy records … person-day of follow-up for cohort members was classified according to probable use of study ADHD drugs … ADHD drugs and cardiovascular risk. N Engl J Med 2006 Apr 6;354(14):1445-8. 6. … Atypical antipsychotic drugs and the risk of sudden cardiac death.
  19. effectivehealthcare.ahrq.gov/sites/default/files/prostatic-hyperplasia-medications_disposition-comments.pdf
    May 26, 2016 - Included trials did not report the impact of the combination of these drugs on blood pressure and we … We revised the sentence to clarify: “Recently, newer drugs and drug in other classes approved for … All drugs are FDA-approved and therefore likely to have trials published in English. … We included drugs ‘newly used’ to treat LUTS attributable to BPH. … Drugs with insufficient evidence were added to the anticholinergics paragraph.
  20. effectivehealthcare.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
    January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Tofacitinib (CP-690,550) in combination with traditional disease-modifying anti- rheumatic drugs:

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