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Total Results: 1,528 records

Showing results for "drugs".

181. Diagnosis and Management of Gout: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
     January 01, 2017 - Treatments for gout attacks include nonsteroidal anti- inflammatory drugs (NSAIDs), colchicine, and … NSAIDs ��� ACTH = adrenocorticotropic hormone; N = number; NSAIDs = nonsteroidal anti-inflammatory drugs … the risk of gout attacks ��� N = number; NR = not reported; NSAIDs = nonsteroidal anti-inflammatory drugs … thromboembolic events, hepatic failure, TEN, SJS, and DRESS NSAIDs = nonsteroidal anti-inflammatory drugs

182. CER 218 Disposition of Comments: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
     April 23, 2019 - Table 5) Comment: Table 4 defines the interventions to be included in this systematic review as “Drugs … to determine whether these harms were associated with long-term treatment with these osteoporosis drugs … Class-Specific Harms of Drugs Used for Osteoporosis Treatment has several important errors. … to determine whether these harms were associated with long-term treatment with these osteoporosis drugs … Results Public Commenter #1 (Rafael Pirtillo Ferman -Altietus College) Drugs still working Thank

183. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
     January 01, 2012 - Optimer Pharmaceuticals announced a 2-year agreement with Cubist Pharmaceuticals, Inc. … Tibotec Pharmaceuticals, Vertex Pharmaceuticals. … Cambridge (MA): Vertex Pharmaceuticals, Inc.; 2012 Feb 23 [accessed 2012 May 21]. [5 p]. … Cambridge (MA): Vertex Pharmaceuticals Incorporated; [accessed 2012 May 17]. [3 p]. … San Diego (CA): Optimer Pharmaceuticals, Inc.; 2011 [accessed 2011 Jul 21]. [4 p].

184. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1512.pdf
     December 29, 2015 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Results The table below lists four topics for which (1) preliminary phase III data for drugs were … Treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs) are used for first-line therapy to … Novartis Pharmaceuticals. 16 week efficacy and 2 year long term safety and efficacy of secukinumab … Novartis Pharmaceuticals. 16 week efficacy and 5 year long term efficacy, safety and tolerability

185. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Autism treatments and drugs. [internet].

186. Disposition of Comments: CER 228, Nonopioid Pharmacologic Treatments for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-228-nonopioid-pharm-chronic-pain-comments.pdf
     April 16, 2020 - of 4 will addict, then there would be ~25 million Americans addicted, and actively seeking illicit drugs … This was a 13-week randomized trial comparing escitalopram with duloxetine and showed that both drugs … Each of the pharmaceuticals studied have unique profiles that make them clinically appropriate for … ASRA recognizes that all drugs – opioid and nonopioid – carry risks. … This report examines the evidence-base for nonopioid drugs used to treat chronic pain, varying by pain

187. Misuse of Prescription Stimulants in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol-amendment.pdf
     November 26, 2024 - For example, emergency department visits related to NMU of these drugs by adults increased from 5,212 … Misuse of Prescription Drugs Research Report. 2023. … https://nida.nih.gov/publications/research-reports/misuse-prescription-drugs/overview. … MMWR https://nida.nih.gov/publications/research-reports/misuse-prescription-drugs/overview https://

188. Migraine-Emergency Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
     November 01, 2012 - ergot derivatives (e.g., dihydroergotamine [DHE]), intravenous (IV) nonsteroidal anti-inflammatory drugs … Food and Drug Administration documents related to the drugs of interest were reviewed for additional … We recognize that many drugs have various effects. … For the mixed-treatment analysis, we identified a group of drugs that were not easily classified and … We refer to these drugs collectively as “orphan agents.”

189. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
     January 01, 2012 - In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … several weeks, following a single infusion. 37,41,42 The drug was originally launched by King Pharmaceuticals … Drugs Future 2009;34(3):217-21. 39. Thomson Reuters Integrity [database online]. … In: Drugs@FDA [internet]. Silver Spring (MD): U.S. … Available: http://www.accessdata.fda.gov/scripts/cder/drugs atfda/index.cfm?

190. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - Vertex Pharmaceuticals, Cystic Fibrosis Foundation. … Vertex Pharmaceuticals Incorporated, Cystic Fibrosis Foundation. … Pricing for orphan drugs: will the market bear what society cannot? … Vertex Pharmaceuticals Incorporated. … Vertex Pharmaceuticals Incorporated.

191. Horizon-Scan Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-protocol.pdf
     December 01, 2011 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … If so, do not select, because these are “me-too” of existing drugs. … Covers future industry trends, key industry developments, research and development of drugs and pharmaceuticals … Industries covered: pharmaceuticals, biotechnology, medical equipment & devices, and in vitro diagnostics

192. Disposition of Comments Report for Treatment of Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
     June 28, 2013 - And for KQ4, comparing anti-arrhythmic drugs (AADs) with electrical cardioversion for restoration of … We have added additional information about whether the drugs were given IV, orally, or a combination … Mascette ES (Results) The inclusion of amiodarone and sotalol as rate-control drugs (pp. … Mascette Results A gender difference in efficacy of drugs (but not proarrhythmia) is mentioned on … Comparative efficacy of rate control drugs is a good example.

193. The Effectiveness of Disease-Modifying Antirheumatic Drugs (DMARDS) in Children With Juvenile Idiopathic Arthritis (JIA) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/juvenile-arthritis-dmards/research-protocol

194. S158 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
     October 01, 2007 - Measures: Association between nonsteroidal antiinflammatory drugs (NSAIDs) and mortality. … In addition, frail elderly patients, who use the most drugs and have the highest adverse event rates, … These databases are, however, often the best source of information on the association between drugs and … diseases, because they allow timely assessment of infrequently used drugs and rare outcomes in large … Selective prescribing led to overestimation of the benefits of lipid-lowering drugs.

195. #05 DEPRESSION (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … Results The table below lists the seven topics for which (1) preliminary phase III data on drugs or … to several weeks, following a single infusion. 29,33,34 The drug was launched in 1966 by King Pharmaceuticals … Drugs Future 2009;34(3):217-21. 31. Thomson Reuters Integrity [database online]. … In: Drugs@FDA [internet]. Silver Spring (MD): U.S.

196. Disposition of Comments for CER 208 Treatment for Bipolar Disorder in Adults A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-adults-disposition-comments.pdf
     August 07, 2018 - Introduction Peer Reviewer #6 “Drugs for acute mania are generally used for shorter periods than … drugs used for treating depression or for maintenance.” – This is often not the case. … The statement is not true of other drugs. Thank you for the clarification. … We revised the sentence to read that some drugs may increase these risks. … Perhaps for clarity “Other drugs for acute mania” could be relabeled “Drugs Not Approved by FDA For

197. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Results The table below lists the two topics for which (1) preliminary phase III data on drugs, phase … A third topic that was in the December 2013 report, the oral tablet ivacaftor (Kalydeco™, Vertex Pharmaceuticals

198. Point-Of-Care Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/point-of-care_research.pdf
     April 01, 2014 - We typically did not review evidence summaries on specific interventions, such as specific drugs or … Dietary Supplements in Adults Taking Cardiovascular Drugs. … Interactions of commonly used dietary supplements with cardiovascular drugs: a systematic review. … Dietary Supplements in Adults Taking Cardiovascular Drugs. … Interactions of commonly used dietary supplements with cardiovascular drugs: a systematic review.

199. Arthritis-Psoriatric Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
     April 01, 2012 - Available therapies for PsA include corticosteroids, oral disease-modifying antirheumatic drugs or … Effective Health Care infliximab) are also classified as antitumor necrosis factor (anti-TNF) drugs … Finally, very little is known about the benefits or risks of these drugs in different patient subgroups … Analytic framework for treatment for psoriatic arthritis DMARDS = disease-modifying antirheumatic drugs … Discussion No head-to-head controlled trials meeting inclusion criteria existed for any drugs in this

200. VU EPC DBD Protocol_AHRQ comments_revised_clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf
     January 30, 2014 - CNS Drugs. 2006;20(7):549-65. PMID: 16800715 41. Newcorn JH, Ivanov I. … BTA Pharmaceuticals Inc., Bridgewater, NJ Bupropion Mylan Pharmaceuticals Inc., Morgantown, WV Selective … New York, NY Citalopram Teva Pharmaceuticals, Sellersville, PA Escitalopram Teva Pharmaceuticals, Sellersville … , PA Paroxetine Teva Pharmaceuticals, Sellersville, PA Fluvoxamine Mylan Pharmaceuticals Inc., Morgantown … ") OR SU.EXACT.EXPLODE("Adrenergic Drugs")) OR (SU.EXACT.EXPLODE("Anticonvulsive Drugs") OR SU.EXACT.EXPLODE