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effectivehealthcare.ahrq.gov/products/back-pain-treatment/clinician
November 15, 2016 - Pharmacological interventions: Nonsteroidal anti- inflammatory drugs (NSAIDs) may be effective in treating … Table 5 : FDA Black Box Warnings for Drugs Used To Treat Low Back Pain
Drugs
FDA Black Box Warning … immediate-release)
Misuse, abuse, addiction, overdose, and death
Nonsteroidal anti-inflammatory drugs … Furthermore, several of the trials evaluating antidepressants were funded by the manufacturers of the drugs
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - .
�� Pharmacological interventions: Nonsteroidal anti-
inflammatory drugs (NSAIDs) may be effective … Furthermore, several of the
trials evaluating antidepressants were funded by the
manufacturers of the drugs … Drugs FDA Black Box Warning
Opioids
(immediate-release)
��Misuse, abuse, addiction, overdose, and … death
Nonsteroidal
anti-inflammatory
drugs
��Cardiovascular thrombotic events, including
myocardial … can be fatal
Antidepressants �� Suicidal thoughts and behaviors
Table 5: FDA Black Box Warnings for Drugs
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-seniors-pneumonia_research.pdf
May 01, 2008 - period
preceding a hospitalization for depression [7], leading to the hypothesis that antidepressant drugs … Most diagnoses, drugs
prescribed ever in the past, and currently prescribed drugs examined were substantially … range of potential signals to be further
tested, did not measure actual exposure to antidepressant drugs … Risk of community-
acquired pneumonia and use of gastric acid-
suppressive drugs. … 536 (4.5) 636 (1.3) 2.24 (1.97 to 2.54)
suicidal ideation 7 (0.1) 19 (0.0) 1.98 (0.78 to 5.07)
drugs
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - they are based on
insufficient or low evidence and the broad categorization
into newer and older drugs … Comparative safety of antiepileptic drugs
during pregnancy. Neurology. 2012 May
22;78(21):1692-9. … Gastrointestinal adverse effects of
antiepileptic drugs in intractable epileptic
patients. … Assessing bioequivalence of generic
antiepilepsy drugs. … Suicidal risk and suicide attempts in
people treated with antiepileptic drugs for
epilepsy.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - they are based on
insufficient or low evidence and the broad categorization
into newer and older drugs … Comparative safety of antiepileptic drugs
during pregnancy. Neurology. 2012 May
22;78(21):1692-9. … Gastrointestinal adverse effects of
antiepileptic drugs in intractable epileptic
patients. … Assessing bioequivalence of generic
antiepilepsy drugs. … Suicidal risk and suicide attempts in
people treated with antiepileptic drugs for
epilepsy.
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effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
January 01, 2012 - In the health care sector, horizon
scanning pertains to identifying new (and new uses of existing) pharmaceuticals … Combination phentermine-topiramate (Qsymia®, Vivus, Inc., Mountain View, CA)
Lorcaserin (Belviq®, Arena Pharmaceuticals … Phentermine-topiramate is a controlled-release formulation
of two separate FDA-approved drugs. … Arena Pharmaceuticals and Eisai announce FDA
approval of Belviq (lorcaserin HCl) for chronic
weight … San Diego
(CA): Arena Pharmaceuticals; 2012 Jun 27
[accessed 2012 Jul 5]. [4 p].
-
effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
January 28, 2016 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … unmet need for new antiviral drugs for treating chronic HCV
infection. … Manufacturers with the most advanced candidates include the Janssen
Pharmaceuticals unit of Johnson … It excluded 72 drugs in 2015, including Harvoni, Sovaldi, and Olysio. … Available:
http://blue.regence.com/trgmedpol/drugs/dru366
.pdf.
91.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
March 09, 2010 - Center Systematic Review Protocol
Project Title: The Effectiveness of Disease-Modifying Antirheumatic
Drugs … Therapy with the so-called disease-modifying anti-rheumatic drugs (DMARDs) has
become an increasingly … These drugs, which operate through a
number of different mechanisms (see Table 2), share the common … effect of limiting radiologic
progression of disease.4 Although these drugs can dramatically improve … There are
many unanswered questions about the safety and effectiveness of these drugs, especially for
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_executive.pdf
June 01, 2013 - to be similar enough to be grouped together
and all beta blocker drugs to be similar enough to be … • Although based on limited studies and use of different
drugs for pretreatment, current evidence … Procedural therapies:
• Transcatheter PVI versus antiarrhythmic drugs
– Based on eight RCTs (five … For KQ 3, our findings underscore the need for additional
studies to compare rate-control drugs with … of the comparative safety and effectiveness
of these different drugs and procedures.
-
effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
January 01, 2012 - For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … Results
The table below lists the four topics for which (1) preliminary phase III data for drugs and … Most
research activity in this priority area is focusing on drugs and biologics for irritable bowel … Curr
Opin Investig Drugs 2001 Apr;2(4):505-9.
PMID: 11566007
43. Tappenden K, Edelman J.
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations
in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … ALZT-OP1's developers hypothesize that
administering these drugs in concert will relieve symptoms of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - This review did not evaluate
pharmacokinetics of the drugs. … into the text of
the report for methotrexate or the other
drugs. … I would also indicate the drugs that you are referring
to. … So a moderate SoE for symptoms only applies to a few drugs not
the entire class. … Specific drugs are
described in the text.
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence.pdf
October 26, 2020 - -2
3 or/1-2 (7262)
4 exp *Therapeutics/ (2522988)
5 (biofeedback or device* or diet* or drug or drugs … (anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug or drugs … ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug or drugs … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug OR drugs … OR+f
ecal+incontinence+OR+faecal+incontinence+%29+AND+%28+biofeedback+OR
+device+OR+diet+OR+drug+OR+drugs
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_2.pdf
October 26, 2020 - -2
3 or/1-2 (7262)
4 exp *Therapeutics/ (2522988)
5 (biofeedback or device* or diet* or drug or drugs … (anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug or drugs … ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug or drugs … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug OR drugs … OR+f
ecal+incontinence+OR+faecal+incontinence+%29+AND+%28+biofeedback+OR
+device+OR+diet+OR+drug+OR+drugs
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_1.pdf
October 26, 2020 - -2
3 or/1-2 (7262)
4 exp *Therapeutics/ (2522988)
5 (biofeedback or device* or diet* or drug or drugs … (anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug or drugs … ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug or drugs … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug OR drugs … OR+f
ecal+incontinence+OR+faecal+incontinence+%29+AND+%28+biofeedback+OR
+device+OR+diet+OR+drug+OR+drugs
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_0.pdf
October 26, 2020 - -2
3 or/1-2 (7262)
4 exp *Therapeutics/ (2522988)
5 (biofeedback or device* or diet* or drug or drugs … (anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug or drugs … ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug or drugs … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug OR drugs … OR+f
ecal+incontinence+OR+faecal+incontinence+%29+AND+%28+biofeedback+OR
+device+OR+diet+OR+drug+OR+drugs
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_12.pdf
October 26, 2020 - -2
3 or/1-2 (7262)
4 exp *Therapeutics/ (2522988)
5 (biofeedback or device* or diet* or drug or drugs … (anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug or drugs … ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug or drugs … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug OR drugs … OR+f
ecal+incontinence+OR+faecal+incontinence+%29+AND+%28+biofeedback+OR
+device+OR+diet+OR+drug+OR+drugs
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_11.pdf
October 26, 2020 - -2
3 or/1-2 (7262)
4 exp *Therapeutics/ (2522988)
5 (biofeedback or device* or diet* or drug or drugs … (anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug or drugs … ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug or drugs … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug OR drugs … OR+f
ecal+incontinence+OR+faecal+incontinence+%29+AND+%28+biofeedback+OR
+device+OR+diet+OR+drug+OR+drugs
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_10.pdf
October 26, 2020 - -2
3 or/1-2 (7262)
4 exp *Therapeutics/ (2522988)
5 (biofeedback or device* or diet* or drug or drugs … (anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug or drugs … ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug or drugs … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug OR drugs … OR+f
ecal+incontinence+OR+faecal+incontinence+%29+AND+%28+biofeedback+OR
+device+OR+diet+OR+drug+OR+drugs
-
effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-fecal-incontinence_9.pdf
October 26, 2020 - -2
3 or/1-2 (7262)
4 exp *Therapeutics/ (2522988)
5 (biofeedback or device* or diet* or drug or drugs … (anal or fecal or faecal) adj incontinen*).ti. (584)
2 (biofeedback or device* or diet* or drug or drugs … ((anal or fecal or faecal) adj incontinen*).ti. (15)
2 (biofeedback or device* or diet* or drug or drugs … incontinence OR fecal incontinence OR faecal incontinence ) AND ( biofeedback OR
device OR diet OR drug OR drugs … OR+f
ecal+incontinence+OR+faecal+incontinence+%29+AND+%28+biofeedback+OR
+device+OR+diet+OR+drug+OR+drugs