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  1. effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_june_2012.pdf
    January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … below lists the three topics for which (1) preliminary phase III or later data were available for drugs … The experts stated oral treprostinil could be used more frequently than other drugs to treat patients
  2. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
    March 01, 2012 - for development of exenatide, leaving sole development responsibility to Amylin Pharmaceuticals. … No major hypoglycemia events occurred. 47 In July 2011, Amylin Pharmaceuticals, Eli Lilly, and … Drugs Future 2008;33(9):745-51. 74. … Selected pharmaceuticals in late stage U.S. and E.U. development or registration. … The Woodlands (TX): Lexicon Pharmaceuticals; [accessed 2011 May 23]. [1 p].
  3. Diabetes Mellitus (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
    March 01, 2012 - for development of exenatide, leaving sole development responsibility to Amylin Pharmaceuticals. … No major hypoglycemia events occurred. 47 In July 2011, Amylin Pharmaceuticals, Eli Lilly, and … Drugs Future 2008;33(9):745-51. 74. … Selected pharmaceuticals in late stage U.S. and E.U. development or registration. … The Woodlands (TX): Lexicon Pharmaceuticals; [accessed 2011 May 23]. [1 p].
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
    March 01, 2012 - This is seldom an issue for antiepileptic drugs unless they are given intraveneously. … However, when we looked at the newer drugs actually compared, there are only but a few newer drugs … Each of these properties clearly impacts the effective selection and use of these drugs. … The problem of pharmacokinetic interactions of other drugs with antiepileptic drugs is important to … - lowering drugs.
  5. effectivehealthcare.ahrq.gov/products/antipsychotics-adults/research-protocol
    December 01, 2010 - New drugs for the treatment of schizophourenic patients. … Developing novel antipsychotic drugs: strategies and goals. … Curr Opin CPNS Invest Drugs 2000;2:25-39. Dawkins K, Lieberman JA, Lebowitz BD, et al. … Effectiveness of antipsychotic drugs in patients with chouronic Schizophrenia. … Comparative effectiveness of antipsychotic drugs.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
    December 01, 2010 - Antipsychotic drugs, neurotransmitters, and Schizophrenia. … New drugs for the treatment of schizophourenic patients. … Developing novel antipsychotic drugs: strategies and goals. … Effectiveness of antipsychotic drugs in patients with chouronic Schizophrenia. … Comparative effectiveness of antipsychotic drugs.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0477_11-01-2011.pdf
    January 01, 2011 - The nominator is also concerned with adverse side effects of pharmaceuticals used to treat fibromyalgia … (e.g., cyclobenzaprine); simple analgesics; opioid analgesics (e.g., tramadol); anti-inflammatory drugs
  8. S66 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
    October 01, 2007 - ORIGINAL ARTICLE Assessment of Adherence to and Persistence on Disease-Modifying Antirheumatic Drugs … Griffin, MD, MPH*§¶ Objective: Biologic disease-modifying antirheumatic drugs (DMARDs) are efficacious … The discontinuation of either of the drugs determined the end of the episode. … The impact of non-compliance on the cost-effectiveness of pharmaceuticals: a review of the literature … New drugs for rheumatoid arthritis. N Engl J Med. 2004;350:2167–2179. 43.
  9. effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine-update/research-protocol
    May 24, 2017 - Newly approved drugs and those under review by the FDA are described in Section B (see Table 1) above … Few data are available on efficacy for these drugs; even less is known about how their effectiveness … and harms compared with that of existing drugs. … What has Changed New drugs: Additional clinical trials of three biosimilar drugs and a tsDMARD (an … Clinical trials of new drugs for the treatment of rheumatoid arthritis: focus on early disease.
  10. S58 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
    October 01, 2007 - powerful and under-used resource for health services research on the use and outcomes of prescription drugs … Key Words: Medicaid, prescription drugs, methodology, claims, outcomes, adherence (Med Care 2007;45: … Whereas participants in randomized clinical trials (RCTs) of drugs sometimes fail to represent the full … Examination of which beneficiaries use which drugs is simply a starting point; further insight can be … while hospitalized, over- the-counter drugs, and nonformulary drugs purchased out-of- pocket.28 Many
  11. effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine-1/research
    March 30, 2009 - Annual age-specific utilization of DMARDs, glucocorticoids, non-steroidal anti-inflammatory drugs (NSAIDs … rheumatoid arthritis, disease modifying anti-rheumatic drugs, epidemiology. … Introduction The treatment of rheumatoid arthritis (RA) with disease modifying anti-rheumatic drugs … Interestingly, about 10% of patients were not using any study drugs on the index dates. … The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis from
  12. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
    October 01, 2011 - work loss.3, 4 Common oral medications for osteoarthritis include nonsteroidal anti- inflammatory drugs … Food and Drug Administration (FDA) as pharmaceuticals, including glucosamine and chondroitin.5 Opioid … In addition, benefits and harms may vary for individual drugs within a class. … Non-steroidal anti- inflammatory drugs. … Non- steroidal anti-inflammatory drugs for low-back pain.
  13. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - (Morrisville, NC), a subsidiary of Valeant Pharmaceuticals International, Inc. … Raleigh (NC): Salix Pharmaceuticals, Inc. 2014 Mar. 19 p. 5. … Raleigh (NC): Salix Pharmaceuticals, Ltd.; 2014 Oct 21 [accessed 2015 Feb 11]. [5 p]. … Salix Pharmaceuticals, Inc. … Raliegh (NC): Salix Pharmaceuticals, Inc.; 2015 May. 7 p.
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-mortality-elderly_research.pdf
    March 01, 2009 - first reported higher mortality in elderly patients taking haloperidol compared with two atypical drugs … FDA warns antipsychotic drugs may be risky for elderly. JAMA 2005 May 25;293(20):2462. 3. … Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using … Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death. … Antipsychotic drugs in dementia: what should be made of the risks?
  15. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Vertex Pharmaceuticals Incorporated. … Vertex Pharmaceuticals Incorporated.
  16. effectivehealthcare.ahrq.gov/health-topics/prescription-drug-abuse?_gl=1*ep2bro*_ga*MzY2OTg1NzkzLjE3MjA0NzgzMzY.*_ga_45NDTD15CJ*MTcyMDQ3ODQ4NS4xLjAuMTcyMDQ3ODQ4NS42MC4wLjA.
  17. effectivehealthcare.ahrq.gov/health-topics/prescription-drug-abuse/
  18. effectivehealthcare.ahrq.gov/products/urinary-incontinence-treatment/research
    April 09, 2012 - Benefits from drugs are small. Drugs for urgency UI have comparable effectiveness.
  19. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-the-elderly-taking-cardiovasculare-medications-what-are-the-comparative-risks-and-benefits-of-commonly-used-herbal-supplements
    April 01, 2009 - no If yes, explain the specific technologies, devices, drugs, or interventions you would like to … about the Effective Health Care Program Dietary Supplements in Adults Taking Cardiovascular Drugs
  20. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-adult-female-patients-what-is-the-comparative-effective-of-non-surgical-and-surgical-treatment-of-chronic-pelvic-pain
    July 21, 2009 - yes If yes, explain the specific technologies, devices, drugs, or interventions you would like to … see compared: Drugs, behavioral treatments and hysterectomy (with or without oophorectomy) What

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