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Total Results: 2,078 records

Showing results for "drugs".

141. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes_hi_impact.pdf
     March 01, 2012 - for development of exenatide, leaving sole development responsibility to Amylin Pharmaceuticals. … No major hypoglycemia events occurred. 47 In July 2011, Amylin Pharmaceuticals, Eli Lilly, and … Drugs Future 2008;33(9):745-51. 74. … Selected pharmaceuticals in late stage U.S. and E.U. development or registration. … The Woodlands (TX): Lexicon Pharmaceuticals; [accessed 2011 May 23]. [1 p].

142. Topic 0590 Strategies to Treat and Manage Infantile Hemangioma NSD FINAL_SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0715-140408.pdf
     April 08, 2014 - Comparator(s): Systemic (enteral) medical therapy using corticosteroids, medical therapy using cytostatic drugs … infantile hemangioma as compared to other medical interventions, including corticosteroids, cytostatic drugs

143. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - (Morrisville, NC), a subsidiary of Valeant Pharmaceuticals International, Inc. … Raleigh (NC): Salix Pharmaceuticals, Inc. 2014 Mar. 19 p. 5. … Raleigh (NC): Salix Pharmaceuticals, Ltd.; 2014 Oct 21 [accessed 2015 Feb 11]. [5 p]. … Salix Pharmaceuticals, Inc. … Raliegh (NC): Salix Pharmaceuticals, Inc.; 2015 May. 7 p.

144. S66 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
     October 01, 2007 - ORIGINAL ARTICLE Assessment of Adherence to and Persistence on Disease-Modifying Antirheumatic Drugs … Griffin, MD, MPH*§¶ Objective: Biologic disease-modifying antirheumatic drugs (DMARDs) are efficacious … The discontinuation of either of the drugs determined the end of the episode. … The impact of non-compliance on the cost-effectiveness of pharmaceuticals: a review of the literature … New drugs for rheumatoid arthritis. N Engl J Med. 2004;350:2167–2179. 43.

145. Comparative Effectiveness of Medications in Patients with Epilepsy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
     March 01, 2012 - This is seldom an issue for antiepileptic drugs unless they are given intraveneously. … However, when we looked at the newer drugs actually compared, there are only but a few newer drugs … Each of these properties clearly impacts the effective selection and use of these drugs. … The problem of pharmacokinetic interactions of other drugs with antiepileptic drugs is important to … - lowering drugs.

146. Comparative Effectiveness of First and Second Generation Antipsychotics in the Adult Population | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/antipsychotics-adults/research-protocol
     December 01, 2010 - New drugs for the treatment of schizophourenic patients. … Developing novel antipsychotic drugs: strategies and goals. … Curr Opin CPNS Invest Drugs 2000;2:25-39. Dawkins K, Lieberman JA, Lebowitz BD, et al. … Effectiveness of antipsychotic drugs in patients with chouronic Schizophrenia. … Comparative effectiveness of antipsychotic drugs.

147. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
     December 01, 2010 - Antipsychotic drugs, neurotransmitters, and Schizophrenia. … New drugs for the treatment of schizophourenic patients. … Developing novel antipsychotic drugs: strategies and goals. … Effectiveness of antipsychotic drugs in patients with chouronic Schizophrenia. … Comparative effectiveness of antipsychotic drugs.

148. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0477_11-01-2011.pdf
     January 01, 2011 - The nominator is also concerned with adverse side effects of pharmaceuticals used to treat fibromyalgia … (e.g., cyclobenzaprine); simple analgesics; opioid analgesics (e.g., tramadol); anti-inflammatory drugs

149. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
     October 01, 2011 - work loss.3, 4 Common oral medications for osteoarthritis include nonsteroidal anti- inflammatory drugs … Food and Drug Administration (FDA) as pharmaceuticals, including glucosamine and chondroitin.5 Opioid … In addition, benefits and harms may vary for individual drugs within a class. … Non-steroidal anti- inflammatory drugs. … Non- steroidal anti-inflammatory drugs for low-back pain.

150. Drug Therapy for Early Rheumatoid Arthritis in Adults – An Update | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine-update/research-protocol
     May 24, 2017 - Newly approved drugs and those under review by the FDA are described in Section B (see Table 1) above … Few data are available on efficacy for these drugs; even less is known about how their effectiveness … and harms compared with that of existing drugs. … What has Changed New drugs: Additional clinical trials of three biosimilar drugs and a tsDMARD (an … Clinical trials of new drugs for the treatment of rheumatoid arthritis: focus on early disease.

151. S58 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
     October 01, 2007 - powerful and under-used resource for health services research on the use and outcomes of prescription drugs … Key Words: Medicaid, prescription drugs, methodology, claims, outcomes, adherence (Med Care 2007;45: … Whereas participants in randomized clinical trials (RCTs) of drugs sometimes fail to represent the full … Examination of which beneficiaries use which drugs is simply a starting point; further insight can be … while hospitalized, over- the-counter drugs, and nonformulary drugs purchased out-of- pocket.28 Many

152. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … Combination phentermine-topiramate (Qsymia®, Vivus, Inc., Mountain View, CA)  Lorcaserin (Belviq®, Arena Pharmaceuticals … Phentermine-topiramate is a controlled-release formulation of two separate FDA-approved drugs. … Arena Pharmaceuticals and Eisai announce FDA approval of Belviq (lorcaserin HCl) for chronic weight … San Diego (CA): Arena Pharmaceuticals; 2012 Jun 27 [accessed 2012 Jul 5]. [4 p].

153. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
     January 01, 2012 - For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Results The table below lists the four topics for which (1) preliminary phase III data for drugs and … Most research activity in this priority area is focusing on drugs and biologics for irritable bowel … Curr Opin Investig Drugs 2001 Apr;2(4):505-9. PMID: 11566007 43. Tappenden K, Edelman J.

154. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_june_2012.pdf
     January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … below lists the three topics for which (1) preliminary phase III or later data were available for drugs … The experts stated oral treprostinil could be used more frequently than other drugs to treat patients

155. Changing Patterns of Medication Use in Patients With Rheumatoid Arthritis in a Medicaid Population | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine-1/research
     March 30, 2009 - Annual age-specific utilization of DMARDs, glucocorticoids, non-steroidal anti-inflammatory drugs (NSAIDs … rheumatoid arthritis, disease modifying anti-rheumatic drugs, epidemiology. … Introduction The treatment of rheumatoid arthritis (RA) with disease modifying anti-rheumatic drugs … Interestingly, about 10% of patients were not using any study drugs on the index dates. … The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis from

156. PHARMACO-EPIDEMIOLOGIC METHODS FOR A STUDY OF (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-mortality-elderly_research.pdf
     March 01, 2009 - first reported higher mortality in elderly patients taking haloperidol compared with two atypical drugs … FDA warns antipsychotic drugs may be risky for elderly. JAMA 2005 May 25;293(20):2462. 3. … Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using … Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death. … Antipsychotic drugs in dementia: what should be made of the risks?

157. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
     January 28, 2016 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … unmet need for new antiviral drugs for treating chronic HCV infection. … Manufacturers with the most advanced candidates include the Janssen Pharmaceuticals unit of Johnson … It excluded 72 drugs in 2015, including Harvoni, Sovaldi, and Olysio. … Available: http://blue.regence.com/trgmedpol/drugs/dru366 .pdf. 91.

158. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - they are based on insufficient or low evidence and the broad categorization into newer and older drugs … Comparative safety of antiepileptic drugs during pregnancy. Neurology. 2012 May 22;78(21):1692-9. … Gastrointestinal adverse effects of antiepileptic drugs in intractable epileptic patients. … Assessing bioequivalence of generic antiepilepsy drugs. … Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.

159. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - they are based on insufficient or low evidence and the broad categorization into newer and older drugs … Comparative safety of antiepileptic drugs during pregnancy. Neurology. 2012 May 22;78(21):1692-9. … Gastrointestinal adverse effects of antiepileptic drugs in intractable epileptic patients. … Assessing bioequivalence of generic antiepilepsy drugs. … Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.

160. Observed Association Between Antidepressant Use and Pneumonia Risk Was Confounded by Comorbidity Measures (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-seniors-pneumonia_research.pdf
     May 01, 2008 - period preceding a hospitalization for depression [7], leading to the hypothesis that antidepressant drugs … Most diagnoses, drugs prescribed ever in the past, and currently prescribed drugs examined were substantially … range of potential signals to be further tested, did not measure actual exposure to antidepressant drugs … Risk of community- acquired pneumonia and use of gastric acid- suppressive drugs. … 536 (4.5) 636 (1.3) 2.24 (1.97 to 2.54) suicidal ideation 7 (0.1) 19 (0.0) 1.98 (0.78 to 5.07) drugs