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Showing results for "drugs".

1381. Data-Points-8 Tables1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/data-points-8_tables1.pdf
      January 01, 2009 - Medicare Parts A, B, and D Beneficiaries With Hypertension, With Use of One or More Antihypertensive Drugs … , With Hypertension and Use of One or More Antihypertensive Drugs, and Average Number of Antihypertensive … Medicare Parts A, B, and D Beneficiaries With Hypertension and Use of One or More Antihypertensive Drugs … Medicare Parts A, B, and D Beneficiaries With Hypertension and Use of One or More Antihypertensive Drugs … Medicare Parts A, B, and D Beneficiaries With Hypertension and Use of One or More Antihypretensive Drugs

1382. Understanding Health-Systems’ Use of and Need for Evidence To Inform Decisionmaking (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-systems-research.pdf
      October 01, 2017 - These reviews focus on a variety of issues, including assessing and comparing clinical drugs, treatments … I feel like the thing that I'm most struggling with from an evidence-based standpoint, is limiting pharmaceuticals … o What are the opportunities to substitute less costly, but equally effective, pharmaceuticals for specific … These reviews focus on a variety of issues, including comparing clinical drugs or treatments, and interventions … o Prevention strategies o Diagnostic strategies o Treatment strategies  Drugs, devices, non-pharmaceuticals

1383. The Refinement of Topics for Systematic Reviews: Lessons and Recommendations From the Effective Health Care Program (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
      January 01, 2013 - Disease-Modifying Antirheumatic Drugs (DMARDs) in Children With Juvenile Idiopathic Arthritis (JIA) … • Include information on the FDA status, indications, and relevant warnings for drugs or devices to … • Include information on the FDA status, indications, and relevant warnings for drugs or devices to … Disease-Modifying Antirheumatic Drugs (DMARDs) in Children With Juvenile Idiopathic Arthritis (JIA) … PICO (Intervention): Corticosteroids; Synthetic disease- modifying anti- rheumatic drugs (DMARDs)

1384. CER 217 Management of Infertility Evidence Summary (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
      May 01, 2019 - use of ovulation-induction agents including oral (clomiphene citrate or letrozole) and injected drugs … Use of fertility drugs and risk of ovarian cancer: results from a U.S.-based case-control study. … Risk of ovarian cancer in women treated with ovarian stimulating drugs for infertility. … Effects of fertility drugs on cancers other than breast and gynecologic malignancies. … Long-term relationship of ovulation-stimulating drugs to breast cancer risk.

1385. Disposition of Comments Report for Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
      January 01, 2014 - Should drugs be administered right before PCI, 6 hours prior, 12 hours prior if possible? … I found the descriptions of the classes of drugs very helpful. … This is already a very large report, and delving further into the background for these drugs is out … UFH given the small number of studies with a head-to- head comparison of those drugs. … However, in KQ 1, all three drugs were compared.

1386. Microsoft Word - finbody.doc (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
      January 01, 2007 - conduct and support research on the comparative outcomes, clinical effectiveness, and appropriateness of pharmaceuticals … currently used interventions, including angioplasty with stent placement and/or those antihypertensive drugs … explicitly evaluated aggressive medical treatment with ACE inhibitors, statins, and anti-platelet drugs … after revascularization do occur in a small percentage of patients, and each of the antihypertensive drugs … eligibility criteria reported analyses of whether periprocedural interventions, such as different drugs

1387. Disposition of Comments Report for Evaluation and Treatment of Tinnitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_disposition-comments.pdf
      August 23, 2013 - Initially, these interventions were grouped together and labeled ‘medical’ because drugs and surgeries … I cannot see any advantage to lumping these drugs together but if you do want to group them, the only … We refer to gabapentin, baclofen, alprazolam, and acamprosate as neurotransmitter drugs and specify … Two of these feature experimental drugs that are not currently commercially available and this may be … Similarly, the grouping of antidepressants were in fact 4 different drugs with differing doses.

1388. Stroke-Atrial-Fibrillation Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
      August 01, 2013 - , Bleeding history or predisposition, Labile international normalized ratio, Elderly [>65 years], Drugs … Despite all the potential advantages of the new drugs demonstrated in the clinical trials when compared … with warfarin, the new drugs still do not have a well-validated and -studied immediate antidote. … The shorter half-life of the novel drugs may help in the management of bleeding episodes in patients … receiving these drugs and should provide comfort that bleeding can be controlled without an antidote

1389. Disposition of Comments for CER 165 Fecal Incontinence (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/fecal-incontinence_disposition-comments.pdf
      March 21, 2016 - For example, the easiest treatments to study (drugs) are not necessarily those that are used most … With diet drugs being 'symptom' and replacing sphincter being 'cure' - the issue would be what does … Stool modifying drugs are listed as BOTH pharmacological treatments and standard care treatments. … We assume that the Reviewer is referring to diet, over the counter drugs, PFMT, education, toileting … offers any advantage over standard care (such as dietary fiber supplementation, stool- modifying drugs

1390. Stakeholder Involvement in Improving Comparative Effectiveness Reviews: AHRQ and the Effective Health Care Program (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement_research.pdf
      September 01, 2011 - support research with a focus on outcomes, comparative clinical effectiveness, and appropriateness of pharmaceuticals … “Treating Type 2 Diabetes, The Oral Diabetes Drugs, comparing Effectiveness, Safety, and Price.” … Consumer Reports Best Buy Drugs. Yonkers, NY: Consumers Union; 2006. 8.

1391. Hypertension-Pulmonary-Arterial Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
      April 01, 2013 - These new data may clarify any effect on mortality and gauge the comparative effectiveness of these drugs … Additionally, combination drug therapy (using multiple drugs with different mechanisms of action) is … In order to 5 optimize PAH care, newer information regarding the latest drugs and combination therapies … compared a single drug (monotherapy) with placebo or standard therapy and included the following drugs … Drugs did not significantly differ in their odds of causing dizziness or diarrhea.

1392. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
      May 22, 2012 - Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation … Catheter ablation versus antiarrhythmic drugs for atrial fibrillation: the A4 study. … nebivolol, timolol) • Calcium channel blockers (verapamil, diltiazem) Clarification that these drugs … nebivolol, timolol) • Calcium channel blockers (verapamil, diltiazem) Clarification that these listed drugs … cardioversion and patient- enabled cardioversion using an ICD • Studies investigating use of antiarrhythmic drugs

1393. uterine-fibroids-protocol-160301 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
      March 01, 2016 -  bleeding;;  In  vitro   fertilization;;  Precocious  puberty;;  Prostate  cancer   AstraZeneca   Pharmaceuticals … indications:     Endometrial  hyperplasia;;  Endometriosis;;   Menopausal  symptom   Bayer  Healthcare   Pharmaceuticals

1394. Hepatitis-C-Screening Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
      November 01, 2012 - injection drug users.16-22 About 60 percent of new infections occur in individuals who report injecting drugs … partners, unprotected sex, and/or sex with a person infected with HCV infection or using injection drugs … Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health

1395. Crosscutting-Horizon-Scan-High-Impact-1312 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1312.pdf
      December 01, 2013 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … It differentiated 100% of multiple drugs and doses taken simultaneously by type and by dose.

1396. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_executive.pdf
      March 01, 2017 - If inflammation is part of the disease process, anti-inflammatory drugs may be effective. … Nonsteroidal Anti- Inflammatory Drugs (NSAIDs) • No evidence was available for the effect of low-dose … Antidementia Treatments • Low-strength evidence shows AChEI antidementia drugs did not reduce the incidence … instrumental activities of daily living; MCI=mild cognitive impairment; NSAIDs=nonsteroidal anti-inflammatory drugs

1397. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline_executive.pdf
      March 01, 2017 - If inflammation is part of the disease process, anti-inflammatory drugs may be effective. … Nonsteroidal Anti- Inflammatory Drugs (NSAIDs) • No evidence was available for the effect of low-dose … Antidementia Treatments • Low-strength evidence shows AChEI antidementia drugs did not reduce the incidence … instrumental activities of daily living; MCI=mild cognitive impairment; NSAIDs=nonsteroidal anti-inflammatory drugs

1398. Disposition of Comments for Diagnostic Accuracy of Screening and Treatment of Post-Acute Coronary Syndrome Depression (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-200-comments-post-acs.pdf
      November 14, 2017 - It is important that this list should not be interpreted as an endorsement of any of these drugs so … this point should be made the first time these drugs are mentioned. … The authors make it clear later in this report that the safety of the majority of these drugs has not … In both COPES and CODIACS, the study psychiatrist prescribed the drugs if the patient preferred an

1399. Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-research-protocol.pdf
      April 11, 2018 - considerations for AECOPD include short- acting/long-acting inhaled bronchodilators, anti-inflammatory drugs … in patients with advanced COPD suffering from an episode of AECOPD is unclear, especially as these drugs … mechanical ventilations • Complementary and alternative medicine interventions • Investigational drugs … and drugs that are only available outside of the U.S

1400. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd_executive.pdf
      September 01, 2011 - $3,355 per employee during a 3-year observation period—approximately 65 percent related to prescription drugs … .1 At the same time, it is well recognized that some drugs used to treat GERD (such as proton pump inhibitors … Among them are the publication of approximately 3,000 new studies; the introduction of novel drugs; the … The large disease burden, economic impact, and market potential for new drugs and devices explain the