-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - they are based on
insufficient or low evidence and the broad categorization
into newer and older drugs … Comparative safety of antiepileptic drugs
during pregnancy. Neurology. 2012 May
22;78(21):1692-9. … Gastrointestinal adverse effects of
antiepileptic drugs in intractable epileptic
patients. … Assessing bioequivalence of generic
antiepilepsy drugs. … Suicidal risk and suicide attempts in
people treated with antiepileptic drugs for
epilepsy.
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1512.pdf
December 01, 2015 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … http://www.cesar.umd.edu/cesar/drugs/ketamine.pdf
http://www.cesar.umd.edu/cesar/drugs/ketamine.pdf
http … J
Psychoactive Drugs. 2015 Sep-Oct;47(4):276-
85. … Rochester (MI):
JHP Pharmaceuticals, LLC; 2012 Mar 01
[accessed 2012 Mar 15]. [6 p]. … Rochester (MI): JHP
Pharmaceuticals, LLC; 2011 Jun. 4 p.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-seniors-pneumonia_research.pdf
May 01, 2008 - period
preceding a hospitalization for depression [7], leading to the hypothesis that antidepressant drugs … Most diagnoses, drugs
prescribed ever in the past, and currently prescribed drugs examined were substantially … range of potential signals to be further
tested, did not measure actual exposure to antidepressant drugs … Risk of community-
acquired pneumonia and use of gastric acid-
suppressive drugs. … 536 (4.5) 636 (1.3) 2.24 (1.97 to 2.54)
suicidal ideation 7 (0.1) 19 (0.0) 1.98 (0.78 to 5.07)
drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_executive.pdf
June 01, 2013 - to be similar enough to be grouped together
and all beta blocker drugs to be similar enough to be … • Although based on limited studies and use of different
drugs for pretreatment, current evidence … Procedural therapies:
• Transcatheter PVI versus antiarrhythmic drugs
– Based on eight RCTs (five … For KQ 3, our findings underscore the need for additional
studies to compare rate-control drugs with … of the comparative safety and effectiveness
of these different drugs and procedures.
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
July 09, 2013 - In the health care sector, horizon
scanning pertains to identifying new (and new uses of existing) pharmaceuticals … Information is compiled for expert comment on topics at a
granular level (i.e., similar drugs in the … The search is on for ways to definitively diagnose AD and for drugs, biologics, and alternative
or … The Horizon Scanning System is tracking several
drugs in late-phase development. … Peripheral and Central Nervous System Drugs
Advisory Committee.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
March 09, 2010 - Center Systematic Review Protocol
Project Title: The Effectiveness of Disease-Modifying Antirheumatic
Drugs … Therapy with the so-called disease-modifying anti-rheumatic drugs (DMARDs) has
become an increasingly … These drugs, which operate through a
number of different mechanisms (see Table 2), share the common … effect of limiting radiologic
progression of disease.4 Although these drugs can dramatically improve … There are
many unanswered questions about the safety and effectiveness of these drugs, especially for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-interventions-comparing_methods.pdf
November 01, 2008 - independent agencies that
inform health care decisionmaking through systematic reviews of technologies, pharmaceuticals … Care (IQWiG) in Germany, the Haute Autorité de Santé (HAS) in France, and the
Canadian Agency for Drugs … research with a focus on
the outcomes, comparative clinical effectiveness, and appropriateness of pharmaceuticals … Reviews
builds on nearly 10 years of experience doing systematic reviews of diverse topics, including
drugs … For example, the results of trials comparing the abilities of
different oral diabetes drugs to control
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_slutsky_comparing_medical_interventions.pdf
November 01, 2008 - independent agencies that
inform health care decisionmaking through systematic reviews of technologies, pharmaceuticals … Care (IQWiG) in Germany, the Haute Autorité de Santé (HAS) in France, and the
Canadian Agency for Drugs … research with a focus on
the outcomes, comparative clinical effectiveness, and appropriateness of pharmaceuticals … Reviews
builds on nearly 10 years of experience doing systematic reviews of diverse topics, including
drugs … For example, the results of trials comparing the abilities of
different oral diabetes drugs to control
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - .
�� Pharmacological interventions: Nonsteroidal anti-
inflammatory drugs (NSAIDs) may be effective … Furthermore, several of the
trials evaluating antidepressants were funded by the
manufacturers of the drugs … Drugs FDA Black Box Warning
Opioids
(immediate-release)
��Misuse, abuse, addiction, overdose, and … death
Nonsteroidal
anti-inflammatory
drugs
��Cardiovascular thrombotic events, including
myocardial … can be fatal
Antidepressants �� Suicidal thoughts and behaviors
Table 5: FDA Black Box Warnings for Drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - We have listed
the included drugs and also how they
were decided upon. … Only studies that
evaluated one of the drugs in Table 1
were eligible. … These drugs could have
been in comparison to a TCA. … to
meaningfully compare drugs in this class and assess their
relative harms. … Thus, it is incorrect to claim
that drugs does not cause adverse events based on public
data.
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
June 01, 2013 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … Vertex Pharmaceuticals Incorporated. … Vertex Pharmaceuticals Incorporated.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - This review did not evaluate
pharmacokinetics of the drugs. … into the text of
the report for methotrexate or the other
drugs. … I would also indicate the drugs that you are referring
to. … So a moderate SoE for symptoms only applies to a few drugs not
the entire class. … Specific drugs are
described in the text.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - dossiers from five pharmaceutical companies
(AstraZeneca, Eli Lilly, GlaxoSmithKline, Warner
Chilcott Pharmaceuticals … • Mirtazapine led to higher weight gains than
comparator drugs. … The
incidence was 8 percent (95% CI, 3 to 11 percent)
higher than with comparator drugs. … The strength of evidence that trazodone
leads to higher rates of somnolence than
comparator drugs is … Evidence of high and moderate strength supports some
differences among individual drugs with respect
-
effectivehealthcare.ahrq.gov/health-topics/prescription-drug-abuse
-
effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1412.pdf
December 22, 2014 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Telaprevir’s manufacturer, Vertex Pharmaceuticals, withdrew the
drug from the market in September 2014 … Viekira Pak: The Viekira Pak (AbbVie, North Chicago, IL, and Enanta Pharmaceuticals,
Inc., Watertown … In 2013, the plan spent $377 million for pharmaceuticals for all of its 600,000 members.
7
Oregon … Cambridge (MA):
Vertex Pharmaceuticals; 2011 May. 23 p.
3. Ferenci P.
-
effectivehealthcare.ahrq.gov/products/juvenile-arthritis-dmards/research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
August 01, 2013 - Five articles12-16
investigated antidepressant drugs versus placebo. … These
drugs included sertraline,12,13 paroxetine,14 trazodone,15
and nortriptyline.16 Dosage levels … The neurotransmitter drugs were gabapentin,17 baclofen,18
alprazolam,19 and acamprosate.20,21 Three … studies
investigated other drugs, including methylprednisolone
versus placebo,22 vardenafil versus … , food
supplements, and other
drugs
Evidence suggests that neurotransmitter drugs showed
improvement
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
November 01, 2017 - characteristics
(e.g., age, type and dose of opioid involved in overdose,
or involvement of other drugs … in overdose, response
to naloxone (e.g., based on Glasgow Coma Scale score),
other substances and drugs … Amphastar Pharmaceuticals. FDA Advisory Committee Briefing
Materials. … Amphastar Pharmaceuticals. … opioide overdose 2016. http://www.fda.gov/downloads/
AdvisoryCommittees/CommitteesMeetingMaterials/Drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the
-
effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1506.pdf
December 01, 2015 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations
in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the