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effectivehealthcare.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
July 09, 2013 - In the health care sector, horizon
scanning pertains to identifying new (and new uses of existing) pharmaceuticals … Information is compiled for expert comment on topics at a
granular level (i.e., similar drugs in the … The search is on for ways to definitively diagnose AD and for drugs, biologics, and alternative
or … The Horizon Scanning System is tracking several
drugs in late-phase development. … Peripheral and Central Nervous System Drugs
Advisory Committee.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_executive.pdf
June 01, 2013 - to be similar enough to be grouped together
and all beta blocker drugs to be similar enough to be … • Although based on limited studies and use of different
drugs for pretreatment, current evidence … Procedural therapies:
• Transcatheter PVI versus antiarrhythmic drugs
– Based on eight RCTs (five … For KQ 3, our findings underscore the need for additional
studies to compare rate-control drugs with … of the comparative safety and effectiveness
of these different drugs and procedures.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
March 09, 2010 - Center Systematic Review Protocol
Project Title: The Effectiveness of Disease-Modifying Antirheumatic
Drugs … Therapy with the so-called disease-modifying anti-rheumatic drugs (DMARDs) has
become an increasingly … These drugs, which operate through a
number of different mechanisms (see Table 2), share the common … effect of limiting radiologic
progression of disease.4 Although these drugs can dramatically improve … There are
many unanswered questions about the safety and effectiveness of these drugs, especially for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - .
�� Pharmacological interventions: Nonsteroidal anti-
inflammatory drugs (NSAIDs) may be effective … Furthermore, several of the
trials evaluating antidepressants were funded by the
manufacturers of the drugs … Drugs FDA Black Box Warning
Opioids
(immediate-release)
��Misuse, abuse, addiction, overdose, and … death
Nonsteroidal
anti-inflammatory
drugs
��Cardiovascular thrombotic events, including
myocardial … can be fatal
Antidepressants �� Suicidal thoughts and behaviors
Table 5: FDA Black Box Warnings for Drugs
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - dossiers from five pharmaceutical companies
(AstraZeneca, Eli Lilly, GlaxoSmithKline, Warner
Chilcott Pharmaceuticals … • Mirtazapine led to higher weight gains than
comparator drugs. … The
incidence was 8 percent (95% CI, 3 to 11 percent)
higher than with comparator drugs. … The strength of evidence that trazodone
leads to higher rates of somnolence than
comparator drugs is … Evidence of high and moderate strength supports some
differences among individual drugs with respect
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - This review did not evaluate
pharmacokinetics of the drugs. … into the text of
the report for methotrexate or the other
drugs. … I would also indicate the drugs that you are referring
to. … So a moderate SoE for symptoms only applies to a few drugs not
the entire class. … Specific drugs are
described in the text.
-
effectivehealthcare.ahrq.gov/health-topics/drug-reactions
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effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Coordinating
Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the
-
effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1506.pdf
December 01, 2015 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations
in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the
-
effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the
-
effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
November 01, 2017 - characteristics
(e.g., age, type and dose of opioid involved in overdose,
or involvement of other drugs … in overdose, response
to naloxone (e.g., based on Glasgow Coma Scale score),
other substances and drugs … Amphastar Pharmaceuticals. FDA Advisory Committee Briefing
Materials. … Amphastar Pharmaceuticals. … opioide overdose 2016. http://www.fda.gov/downloads/
AdvisoryCommittees/CommitteesMeetingMaterials/Drugs
-
effectivehealthcare.ahrq.gov/products/juvenile-arthritis-dmards/research
-
effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1306.pdf
June 01, 2013 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … In the health care sector, horizon
scanning pertains to identifying new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … Autism treatments and drugs.
[internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
August 01, 2013 - Five articles12-16
investigated antidepressant drugs versus placebo. … These
drugs included sertraline,12,13 paroxetine,14 trazodone,15
and nortriptyline.16 Dosage levels … The neurotransmitter drugs were gabapentin,17 baclofen,18
alprazolam,19 and acamprosate.20,21 Three … studies
investigated other drugs, including methylprednisolone
versus placebo,22 vardenafil versus … , food
supplements, and other
drugs
Evidence suggests that neurotransmitter drugs showed
improvement
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effectivehealthcare.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
January 01, 2012 - For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … Results
The table below lists the four topics for which (1) preliminary phase III data for drugs and … Most
research activity in this priority area is focusing on drugs and biologics for irritable bowel … Curr
Opin Investig Drugs 2001 Apr;2(4):505-9.
PMID: 11566007
43. Tappenden K, Edelman J.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
November 27, 2012 - , just as non-
biologics for psoriasis are not considered a “class” of drugs either. … We have added
the terms biologic and nonbiologic to our
glossary with a listing of the drugs which … Suggest specifically mentioning the nonbiologic drugs. Thank you for this suggestion. … Are they
naïve to both drugs (mtx, adalimumab, etanercept?)
Thank you for this suggestion. … More information about each of the drugs
and phototherapy would be helpful.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
May 15, 2017 - Newly approved drugs and those under review by the FDA are described in Section B
(see Table 1) above … Few data are available on efficacy for these drugs; even less is
known about how their effectiveness … and harms compared with that of existing drugs. … What has Changed
New drugs: Additional clinical trials of three biosimilar drugs and a tsDMARD (an … Clinical trials of new drugs
for the treatment of rheumatoid arthritis: focus on early disease.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
September 01, 2011 - A few years ago, these drugs were all off label for autism, depression,
augmentation of depression, … Actually, we refrained from
doing pooled analyses across,
drugs in response to reviewers
comments … So, we think the
report is suitably restrained on
drawing conclusions across
drugs. … As these drugs are
approved for use in MDD, rationale for inclusion of the data in the report should … The drugs
are still included in the
chart for comparative
purposes.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-1_research.pdf
February 01, 2009 - Annual age-specific utilization of DMARDs, glucocorticoids, non-steroidal anti-
inflammatory drugs (NSAIDs … rheumatoid arthritis, disease modifying anti-rheumatic drugs, epidemiology
Effective Health Care … 8
Introduction
The treatment of rheumatoid arthritis (RA) with disease modifying anti-rheumatic drugs … Interestingly, about 10% of patients were not using any study drugs on
the index dates. … The changing
use of disease-modifying anti-rheumatic drugs in
individuals with rheumatoid arthritis