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effectivehealthcare.ahrq.gov/products/eccs-2006/white-paper
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effectivehealthcare.ahrq.gov/sites/default/files/14_substance_abuse_potential_high_impact_2012-12-11.pdf
January 01, 2012 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … Results
The table below lists two topics for which (1) preliminary phase III data were available for
drugs … Prescription drugs: abuse and addiction. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
March 10, 2010 - The lack of information about who is most likely to
experience adverse affects from the drugs. … Nowhere in the medical literature are these drugs
considered "chemotherapy". … After all, some women on all of the drugs got breast cancer. … We did not attempt to combine trials of different drugs. … Is there any literature about any of
these drugs with women younger than 50?
-
effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
October 01, 2007 - ORIGINAL ARTICLE
Assessment of Adherence to and Persistence on
Disease-Modifying Antirheumatic Drugs … Griffin, MD, MPH*§¶
Objective: Biologic disease-modifying antirheumatic drugs (DMARDs)
are efficacious … The discontinuation of
either of the drugs determined the end of the episode. … The impact of non-compliance
on the cost-effectiveness of pharmaceuticals: a review of the literature … New drugs for rheumatoid arthritis. N Engl J Med.
2004;350:2167–2179.
43.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - work loss.3, 4
Common oral medications for
osteoarthritis include nonsteroidal anti-
inflammatory drugs … Food and Drug Administration
(FDA) as pharmaceuticals, including
glucosamine and chondroitin.5 Opioid … In addition, benefits and
harms may vary for individual drugs within
a class. … Non-steroidal anti-
inflammatory drugs. … Non-
steroidal anti-inflammatory drugs for low-back pain.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0404_01-14-2011.pdf
January 01, 2011 - treatment might be severity dependent and should be
defined by functional class
Intervention(s): Newer drugs … failure, improved dyspnea, improved functional class, improved quality of life);
side effects of various drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/07_diabetes_potential_high_impact_june_2012.pdf
January 01, 2012 - They
are extended-release exenatide for injection (Bydureon
™
, Amylin Pharmaceuticals, Inc., San … exenatide, leaving sole
development responsibility to Amylin Pharmaceuticals. … No major
hypoglycemia
events occurred.
47
In July 2011, Amylin Pharmaceuticals, Eli Lilly, and … San Diego (CA): Amylin
Pharmaceuticals, Inc.; 2012 Jan 27 [accessed
2012 Feb 20]. [4 p]. … San
Diego (CA): Amylin Pharmaceuticals, Inc.; 2012
Jan 27. 11 p.
-
effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
January 28, 2016 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … unmet need for new antiviral drugs for treating chronic HCV
infection. … Manufacturers with the most advanced candidates include the Janssen
Pharmaceuticals unit of Johnson … It excluded 72 drugs in 2015, including Harvoni, Sovaldi, and Olysio. … Available:
http://blue.regence.com/trgmedpol/drugs/dru366
.pdf.
91.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
March 01, 2012 - This is seldom an issue for antiepileptic drugs unless they are
given intraveneously. … However, when we looked at the
newer drugs actually compared, there are only
but a few newer drugs … Each of these properties clearly impacts the
effective selection and use of these drugs. … The problem of
pharmacokinetic interactions of other drugs with
antiepileptic drugs is important to … -
lowering drugs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0477_11-01-2011.pdf
January 01, 2011 - The nominator is also concerned with
adverse side effects of pharmaceuticals used to treat fibromyalgia … (e.g., cyclobenzaprine); simple analgesics; opioid analgesics (e.g.,
tramadol); anti-inflammatory drugs
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - Antipsychotic drugs, neurotransmitters, and Schizophrenia. … New drugs for the treatment of schizophourenic patients. … Developing novel antipsychotic
drugs: strategies and goals. … Effectiveness of antipsychotic drugs in
patients with chouronic Schizophrenia. … Comparative effectiveness of antipsychotic drugs.
-
effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
October 01, 2007 - powerful and under-used resource for health services
research on the use and outcomes of prescription drugs … Key Words: Medicaid, prescription drugs, methodology, claims,
outcomes, adherence
(Med Care 2007;45: … Whereas participants in
randomized clinical trials (RCTs) of drugs sometimes fail to
represent the full … Examination of which beneficiaries use which drugs is simply a starting point; further
insight can be … while hospitalized, over-
the-counter drugs, and nonformulary drugs purchased out-of-
pocket.28
Many
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1512.pdf
December 01, 2015 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … http://www.cesar.umd.edu/cesar/drugs/ketamine.pdf
http://www.cesar.umd.edu/cesar/drugs/ketamine.pdf
http … J
Psychoactive Drugs. 2015 Sep-Oct;47(4):276-
85. … Rochester (MI):
JHP Pharmaceuticals, LLC; 2012 Mar 01
[accessed 2012 Mar 15]. [6 p]. … Rochester (MI): JHP
Pharmaceuticals, LLC; 2011 Jun. 4 p.
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations
in drugs … health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … ALZT-OP1's developers hypothesize that
administering these drugs in concert will relieve symptoms of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-mortality-elderly_research.pdf
March 01, 2009 - first reported higher
mortality in elderly patients taking haloperidol compared with two atypical drugs … FDA warns antipsychotic drugs
may be risky for elderly. JAMA 2005 May
25;293(20):2462.
3. … Cardiac arrest and ventricular arrhythmia in
patients taking antipsychotic drugs: cohort
study using … Antipsychotic
drugs: prolonged QTc interval, torsade de
pointes, and sudden death. … Antipsychotic drugs
in dementia: what should be made of the risks?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - they are based on
insufficient or low evidence and the broad categorization
into newer and older drugs … Comparative safety of antiepileptic drugs
during pregnancy. Neurology. 2012 May
22;78(21):1692-9. … Gastrointestinal adverse effects of
antiepileptic drugs in intractable epileptic
patients. … Assessing bioequivalence of generic
antiepilepsy drugs. … Suicidal risk and suicide attempts in
people treated with antiepileptic drugs for
epilepsy.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - they are based on
insufficient or low evidence and the broad categorization
into newer and older drugs … Comparative safety of antiepileptic drugs
during pregnancy. Neurology. 2012 May
22;78(21):1692-9. … Gastrointestinal adverse effects of
antiepileptic drugs in intractable epileptic
patients. … Assessing bioequivalence of generic
antiepilepsy drugs. … Suicidal risk and suicide attempts in
people treated with antiepileptic drugs for
epilepsy.
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_slutsky_comparing_medical_interventions.pdf
November 01, 2008 - independent agencies that
inform health care decisionmaking through systematic reviews of technologies, pharmaceuticals … Care (IQWiG) in Germany, the Haute Autorité de Santé (HAS) in France, and the
Canadian Agency for Drugs … research with a focus on
the outcomes, comparative clinical effectiveness, and appropriateness of pharmaceuticals … Reviews
builds on nearly 10 years of experience doing systematic reviews of diverse topics, including
drugs … For example, the results of trials comparing the abilities of
different oral diabetes drugs to control
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-interventions-comparing_methods.pdf
November 01, 2008 - independent agencies that
inform health care decisionmaking through systematic reviews of technologies, pharmaceuticals … Care (IQWiG) in Germany, the Haute Autorité de Santé (HAS) in France, and the
Canadian Agency for Drugs … research with a focus on
the outcomes, comparative clinical effectiveness, and appropriateness of pharmaceuticals … Reviews
builds on nearly 10 years of experience doing systematic reviews of diverse topics, including
drugs … For example, the results of trials comparing the abilities of
different oral diabetes drugs to control
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-seniors-pneumonia_research.pdf
May 01, 2008 - period
preceding a hospitalization for depression [7], leading to the hypothesis that antidepressant drugs … Most diagnoses, drugs
prescribed ever in the past, and currently prescribed drugs examined were substantially … range of potential signals to be further
tested, did not measure actual exposure to antidepressant drugs … Risk of community-
acquired pneumonia and use of gastric acid-
suppressive drugs. … 536 (4.5) 636 (1.3) 2.24 (1.97 to 2.54)
suicidal ideation 7 (0.1) 19 (0.0) 1.98 (0.78 to 5.07)
drugs