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Showing results for "drugs".

61. Case Study Comparing Bayesian and Frequentist Approaches for Multiple Treatment Comparisons | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/indirect-comparisons/research
    September 01, 2019 - research grant databases up to November 2011 to find randomized studies published in English that examined drugs … In our study, two drugs emerged as attractive because while neither had any significant chance of being … among the least safe drugs, both had greater than 50 percent chances of being among the top three drugs

62. PEPTIC ULCER #11 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - NPS Pharmaceuticals, Inc.. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2014 Jun. 18 p. 8. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2011 May 12 [accessed 2011 Jul 15]. [2 p]. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2011 Oct 31 [accessed 2011 Nov 11]. [4 p]. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2012 Dec 21. 45 p. 14.

63. Evaluation of Effectiveness and Safety of Antiepileptic Medications in Patients With Epilepsy (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
    February 01, 2008 - Antiepileptic Drugs. Fifth ed. … Antiepileptic Drugs. Fourth ed. New York, Raven Press; 1995. p. 799-806. 19. … Antiepileptic Drugs. Fifth ed. … Therapeutic equivalence of generic drugs letter to health practitioners. … Are there potential problems with generic substitution of antiepileptic drugs?

64. S9 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/s9.pdf
    October 01, 2007 - detailed (including beneficiary identifiers, contract identifiers pharmacy provider infor- mation on drugs … Key Words: Medicare, Part D, pharmaceuticals (Med Care 2007;45: S9–S12) The Medicare Part D benefit … Part D plan covers 15%, and the beneficiary pays a 5% coinsurance, or copayments of $2 for generic drugs … and $5 for nongeneric drugs. … Drugs provided (including the National Drug Classifica- tion �NDC� code, compound code, and quantity

65. Nonopioid Pharmacologic Treatments for Chronic Pain: Evidence Summary (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
    April 01, 2020 - for Chronic Pain: Evidence Summary Purpose of Review Evaluate the benefits and harms of nonopioid drugs … neuropathy/post-herpetic neuralgia and fibromyalgia, and small with nonsteroidal anti-inflammatory drugs … (NSAIDs), acetaminophen, topical formulations such as capsaicin, and drugs used for other conditions … Few differences were found between drugs. … Differences were not found between drugs or doses.

66. Dietary Supplements | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/dietary-supplements
    July 25, 2017 - Supplements do not have to go through the testing that drugs do. … Systematic Review Archived April 30, 2012 Dietary Supplements in Adults Taking Cardiovascular Drugs … Effectiveness of Dietary Supplement Versus No Dietary Supplement Use in Adults Taking Cardiovascular Drugs

67. Off-Label Use of Atypical Antipsychotics: An Update | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/atypical-antipsychotics-off-label-update/research
    March 01, 2020 - Food and Drug Administration (FDA) for treatment of schizophrenia, bipolar disorder, and for some drugs … We performed a systematic review on the efficacy and safety of atypical antipsychotic drugs for use in … meta-analysis and 10 trials of risperidone or olanzapine for PTSD, 36 trials for depression of which 7 assessed drugs

68. A Multicenter, Observational Cohort Study to Assess the Cardiovascular Risks of Medications Prescribed for Attention Deficit Hyperactivity Disorder | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/adhd-medicines-risks/abstract
    December 01, 2019 - now are more than 2.5 million children and 1.5 million adults in the United States. who receive ADHD drugs … Reporting System (AERS) for cases of sudden death and arrhythmias in conjunction with use of these drugs … ADHD drugs and serious cardiovascular events in children and young adults. N Engl J Med 2011 Nov 1.

69. PULMONARY with "Discussions" in Exec Summary (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1506.pdf
    October 01, 2015 - Boston (MA): Vertex Pharmaceuticals, Inc.; 2014 Nov 05 [accessed 2014 Dec 11]. [3 p]. … Boston (MA): Vertex Pharmaceuticals Inc.; 2015 Jan 11 [accessed 2015 May 13]. [5 p]. … Boston (MA): Vertex Pharmaceuticals Inc.; 2015 May 12 [accessed 2015 May 13]. [2 p]. … Boehringer Ingelheim Pharmaceuticals, Inc. … Ridgefield (CT): Boehringer Ingelheim Pharmaceuticals, Inc.; 2014 Oct. 18 p.

70. #14 SUBSTANCE ABUSE (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/14_substanceabuse_potential_high_impact_june_2012.pdf
    January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … However, experts shared the belief that these drugs’ benefits would prove to be only incremental … Prescription drugs: abuse and addiction. [internet].

71. #05 DEPRESSION (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Available: http://www.cesar.umd.edu/cesar/drugs/ketamine. pdf. 4. … CNS Drugs. 2012 Mar 1;26(3):189-204. … http://www.cesar.umd.edu/cesar/drugs/ketamine.pdf http://www.cesar.umd.edu/cesar/drugs/ketamine.pdf http … Rochester (MI): JHP Pharmaceuticals, LLC; 2011 Jun. 4 p.

72. #06 Developmental Delays ADHD, and Autism (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/06_devdelays_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … These drugs will probably face intense scrutiny, considering the challenges of accurately diagnosing

73. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
    January 01, 2007 - Available therapies for RA include corticosteroids; synthetic disease-modifying antirheumatic drugs, … Finally, very little is known about the benefits or risks of these drugs in different patient subgroups … : comparative risk of harms: infliximab) vs. anti-TNF Moderate Low drugs Biologic DMARDs vs. … Moderate Moderate In patients with no previous use of study drugs, higher ACR 20/50 response rates … Adjusted indirect comparisons also indicated that anakinra has lower efficacy than anti-TNF drugs.

74. Financing and Economics of Conducting N-of-1 Trials (Chapter 3) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-2
    August 01, 2019 - successful resolution of therapeutic uncertainty in specific patients when the underlying condition and drugs … approach have been well described. 7-9 At times, clinicians may simply give a patient two or more drugs … If two active comparator drugs were used, patients were crossed over from one active drug to another, … This experience is consistent with reports of new or more common significant side effects when drugs … , especially for commonly used or expensive drugs.

75. Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression: An Update of the 2007 Comparative Effectiveness Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antidepressants-update/research
    December 01, 2019 - These drugs include selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake … inhibitors (SNRIs), and other drugs with related mechanisms of action that selectively target neurotransmitters … Statistically significant differences in response rates between some drugs are small and likely not clinically … sertraline to higher rates of diarrhea, and mirtazapine to higher rates of weight gain than comparator drugs

76. Dietary-Supplements Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
    April 01, 2012 - Comparative Effectiveness Review Number 51 Dietary Supplements in Adults Taking Cardiovascular Drugs … (when compared with cardiovascular drugs alone or cardiovascular drugs and a different dietary supplement … • Studies included cardiovascular drugs not marketed in the United States. … Drugs Aging. 2009 Dec;26(Suppl 1):41-51. PMID: 20136168. 13. Garner JB. … Dietary Supplements in Adults Taking Cardiovascular Drugs.

77. DEcIDE 32: The Incident User Design in Comparative Effectiveness Research (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
    May 01, 2012 - ...............................................................................3 Recently Marketed Drugs … If newer drugs were started more recently, the newer drugs may appear safer than older drugs because … their apparent rate would be lower; investigators would observe a higher event rate for older drugs … in a class; requiring all patients in the cohort to have a 365-day window without use of any drugs … For drugs that are available as combination products, it is important to handle the baseline period

78. The Effectiveness of Disease-Modifying Antirheumatic Drugs (DMARDS) in Children With Juvenile Idiopathic Arthritis (JIA) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/juvenile-arthritis-dmards/research-protocol
    December 01, 2019 - Evidence Reports The Effectiveness of Disease-Modifying Antirheumatic Drugs … SHARE: The Effectiveness of Disease-Modifying Antirheumatic Drugs … Therapy with the so-called disease-modifying anti-rheumatic drugs (DMARDs) has become an increasingly … of limiting radiologic progression of disease. 4 Although these drugs can dramatically improve the … There are many unanswered questions about the safety and effectiveness of these drugs, especially for

79. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
    September 01, 2011 - Disease-Modifying Antirheumatic Drugs (DMARDs) in Children With Juvenile Idiopathic Arthritis (JIA) … Treatment with the class of agents known as disease-modifying anti- rheumatic drugs (DMARDs) has become … , which are created by biologic processes, or non-biologic drugs, which are manufactured chemically. … Furthermore, it is possible that the effectiveness of these drugs varies by category of JIA. … be used for difficult-to-treat JIA, or the impact of using multiple drugs.

80. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
    November 03, 2011 - The FDA has approved no drugs for migraine prevention in children. … prevention, which include novel antiepileptic drugs, calcium channel modulators, glutamate blockers … o Use of drugs for acute migraine (prescribed or over-counter). … Drugs approved by the FDA for migraine prevention and off-label drugs examined in clinical trials. … Studies that examined eligible drugs on populations with other diseases.