-
effectivehealthcare-admin.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
June 01, 2014 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … available in generic form from several
manufacturers, as well as in branded form, as Ketalar® (JHP Pharmaceuticals … CNS Drugs. 2012 Mar
1;26(3):189-204. … PMID:
14640353
http://www.cesar.umd.edu/cesar/drugs/ketamine.pdf
http://www.cesar.umd.edu/cesar/drugs … Rochester (MI): JHP
Pharmaceuticals, LLC; 2011 Jun. 4 p.
-
effectivehealthcare-admin.ahrq.gov/products/arthritis-psoriatric/research-protocol
December 01, 2019 - Available therapies for PsA include corticosteroids, oral disease-modifying antirheumatic drugs (DMARDs … Finally, very little is known about the benefits or risks of these drugs in different patient subgroups … Simponi®
Tocililizumab
Actemra®, RoActemrai®
Comparators:
All key questions: all review drugs
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_executive.pdf
September 01, 2011 - Currently, nine atypical antipsychotic drugs
have been approved by FDA: aripiprazole,
asenapine, clozapine … These drugs
have been used off-label (i.e., for
indications not approved by FDA) for the
treatment of … While it is legal for a physician to
prescribe drugs in such a manner, it is
illegal for the manufacturer … How do they compare within
the class and with other drugs used for the conditions? … How do they
compare within the class and with other drugs used for
the conditions?
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1312.pdf
January 01, 2016 - San Diego (CA): Amylin
Pharmaceuticals, Inc.; 2010 Jun 15 [accessed
2011 Feb 22]. [3 p]. … Amylin Pharmaceuticals. … San Diego (CA): Amylin
Pharmaceuticals, Inc.; 2012 Jan 27 [accessed
2012 Feb 20]. [4 p]. … San
Diego (CA): Amylin Pharmaceuticals, Inc.; 2012
Jan 27. 11 p. … Get drugs straight to the eye.
[internet].
-
effectivehealthcare-admin.ahrq.gov/products/migraine-treatments/protocol
March 01, 2020 - However, simple analgesics including nonsteroidal anti-inflammatory drugs (NSAIDs) used on 15 or more … reason, the American Headache Society has explicitly stated that opioids and butalbital-containing drugs … therapy versus: (1) nonopioid pharmacologic therapy (e.g., acetaminophen, nonsteroidal anti-inflammatory drugs … effectiveness of nonopioid pharmacologic therapy (e.g., acetaminophen, nonsteroidal anti-inflammatory drugs … infusion, topical nonopioid abortive drug, including:
Acetaminophen
Nonsteroidal anti-inflammatory drugs
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
January 09, 2020 - However, simple analgesics including
2
nonsteroidal anti-inflammatory drugs (NSAIDs) used … reason, the American Headache Society has explicitly stated
that opioids and butalbital-containing drugs … therapy versus: 1) nonopioid
pharmacologic therapy (e.g., acetaminophen, nonsteroidal anti-inflammatory drugs … effectiveness of nonopioid pharmacologic therapy (e.g.,
acetaminophen, nonsteroidal anti-inflammatory drugs … , topical nonopioid abortive
drug, including:
• Acetaminophen
• Nonsteroidal anti-inflammatory drugs
-
effectivehealthcare-admin.ahrq.gov/products/pneumonia-antibiotic-treatment/research-protocol
December 01, 2019 - For drugs with a narrow therapeutic index, such as vancomycin and the aminoglycosides, the risk of toxicities … also reduce nephrotoxicity in patients who are receiving aggressive dosing, concurrent nephrotoxic drugs … discussion, a new KQ was added to examine the effect of using prolonged or continuous infusions of drugs … creatinine clearance, time above MIC, and ratio of AUC to MIC (see Table 1 below for drug classes and drugs … Relationship OR MIC OR AUC OR Microbial Sensitivity OR Time Kill Curve)
Antibiotics
(Terms for drugs
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research.pdf
July 01, 2012 - In
isolation, identifying specific drugs to avoid is not sufficient for improving safety. … Drugs
2009;69(4):393-406.
21. Touchette DR, Burns AL, Bough MA, et al. … Different brand name drugs have
different Orange Book AB ratings, and generics vary in their combination … If so, with what drugs and what was the reaction?
2. What is your height?
3. … C4.6
C4.7
C4.8
C4.9
C4.10
Patient forgets to use/take drug
Patient has concerns with drugs
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
August 01, 2017 - Food and Drug Administration (FDA) has
approved several prescription drugs for insomnia, typically … Food and Drug Administration
(FDA) for insomnia.
d Other benzodiazepines include drugs approved by … the FDA for insomnia (estazolam, flurazepam, lorazepam, quazepam, and triazolam) and drugs
not approved
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
May 01, 2006 - trials
comparing darbepoetin to epoetin showed no
statistically significant difference between these
drugs … trials comparing
darbepoetin to epoetin showed no statistically
significant difference between these drugs … trials comparing
darbepoetin to epoetin showed no statistically
significant difference between these drugs
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_research-protocol.pdf
December 06, 2010 - Available therapies for RA include
corticosteroids, oral disease-modifying antirheumatic drugs (DMARDs … Finally, very little is known about the
benefits or risks of these drugs AMONG different patient subgroups … review did not include certolizumab pegol, golimumab,
and tocilizumab (listed above), because these drugs … Golimumab Simponi®
Tocililizumab Actemra®, RoActemrai®
• Comparators:
For all KQs: all review drugs
-
effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/1-which-patients-benefit-the-most-from-mtm-services-11-which-factors-or-combinations-of-factors-are-most-predictive-of-the-clinical-benefit-of-mtm-services-111-disease-factors-eg-diabetes-vs-copd-multi-morbidity-vs-single-di
November 01, 2017 - on medications, patient out-of-pocket expenditures on medications, or type of medication [high-risk drugs … yes
If yes, explain the specific technologies, devices, drugs, or interventions you would like to
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/s16.pdf
October 01, 2007 - controlled trials (RCTs) remain the ac-
cepted “gold standard” for determining the efficacy of new drugs … Follow-up and monitoring is
designed to promote adherence to the drugs under study and
to detect any … Drug coverage—Which bisphosphonate drugs should be included on a
drug fomulary? … , quality of intervention
Timing of intervention
Cointerventions, quality of care
Adherence (for drugs … Treatment with drugs to lower
blood pressure and blood cholesterol based on an individual’s absolute
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/s89.pdf
October 01, 2007 - Rapid Cycle
Analysis Team
Background: Rare but serious adverse events associated with vac-
cines or drugs … meningococcal vaccine, drug safety
(Med Care 2007;45: S89–S95)
Concerns about the safety of vaccines and drugs … the
Centers for Disease Control and Prevention (CDC) and Food
and Drug Administration (FDA) and, for drugs … In addition, because drugs treat specific conditions, the pool
of users for a new medication is limited … early detection of potential adverse events after the
introduction of new vaccines, and possibly new drugs
-
effectivehealthcare-admin.ahrq.gov/products/diabetes-glucose-control/research
January 01, 2020 - Exenatide, manufactured as Byetta by Amylin Pharmaceuticals, Inc. … Additionally, a separate, linkable file is available which includes pharmacy claims for prescription drugs … In Table 3 , we provide details about the other drugs for DM used by these patients. … Experts weigh in on promotion, prescription of off-label drugs. JAMA 2007;297:683-684.
-
effectivehealthcare-admin.ahrq.gov/products/insomnia/clinician
March 01, 2021 - Food and Drug Administration (FDA) has approved several prescription drugs for insomnia, typically for … d Other benzodiazepines include drugs approved by the FDA for insomnia (estazolam, flurazepam, lorazepam … , quazepam, and triazolam) and drugs not approved by the FDA for insomnia (alprazolam and clonazepam)
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Coordinating Council for Comparative Effectiveness
Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs,
devices, procedures … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … Cambridge
(MA): Aegerion Pharmaceuticals, Inc.; 2012 Dec.
12 p. … Cambridge (MA):
Aegerion Pharmaceuticals, Inc.; 2013 Apr. 12 p.
-
effectivehealthcare-admin.ahrq.gov/products/management-infantile-epilepsy/research
March 01, 2023 - about initiate the diet rated fewer seizures as their top priority (65-69%); however, need for fewer drugs … Although parents worry about both short and long term adverse effects from drugs, included studies only … However, without randomization, inferring efficacy for drugs, dietary, and surgical therapies is likely … For example, although many different drugs and combinations of drugs are currently used in this population … , we only identified evidence for five drugs of which only levetiracetam had evidence sufficient to conclude
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/multinational-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - focused on the outcomes, effectiveness, comparative clinical
effectiveness, and appropriateness of pharmaceuticals … Food and Drug Administration [FDA], Health
Canada, Japanese Pharmaceuticals and Medical Devices Agency … http://www.fda.gov/downloads/Drugs/Drug
Safety/ucm089809.pdf. Accessed January
10, 2017.
21. … http://www.fda.gov/downloads/Drugs/Guida
nces/ucm073122.pdf. Accessed January 10,
2017.
37. … /downloads/Drugs/DrugSafety/ucm089809.pdf
http://www.wma.net/en/30publications/10policies/b3/
http://
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - most regulatory approvals, and the source of most advertising and other claims made on
behalf of drugs … For example,
a systematic review of nonsteroidal anti-inflammatory drugs (NSAIDs) found cyclo-oxygenase … Do selective
cyclo-oxygenase-2 inhibitors and traditional
non-steroidal anti-inflammatory drugs … Gastrointestinal toxicity with celecoxib vs
nonsteroidal anti-inflammatory drugs for
osteoarthritis … Causality assessment
of adverse reactions to drugs—I.