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Showing results for "drugs".

41. Evidence Report on the (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
    August 05, 2010 - Patients with osteoarthritis also use over-the-counter supplements not regulated by the FDA as pharmaceuticals … Pharmacokinetics, Indications, and Dosing of drugs to be included. … Oral drugs (trade names provided only for drugs under patent) Drug (any trade name): acetaminophen … Non-steroidal anti-inflammatory drugs. … Non-steroidal anti-inflammatory drugs for low-back pain.

42. Case Study Comparing Bayesian and Frequentist Approaches for Multiple Treatment Comparisons (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
    March 01, 2013 - Trospium chloride 60 mg once daily Placebo Esprit Pharma and Indevus Pharmaceuticals Inc. … (formerly Indevus Pharmaceuticals Inc.). … Oxybutynin 2.5 mg twice daily Placebo Funded by Smith and Nephew Pharmaceuticals Ltd. … chloride Propantheline and placebo Pharmcia Leo Therapeutics, Helsingborg, Sweden provided the pharmaceutical … preparations used in this study Toglia, 201075 Study: Post-hoc Karram, 200939 VENUS N: 739

43. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0024_06-09-2008.pdf
    January 01, 2008 - manic or depressive phases, rapid cycling, mixed states), do the typical and atypical antipsychotic drugs … For adults experiencing a first episode of schizophrenia, do the atypical antipsychotic drugs differ … comparative evidence that differences in adherence or persistence among the atypical antipsychotic drugs … developmental disorders or disruptive behavior disorders, do the typical and atypical antipsychotic drugs … Behavioral and Psychological Symptoms of Dementia (BPSD), do the typical and atypical antipsychotic drugs

44. Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics – Update | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/atypical-antipsychotics-off-label-update/research-protocol
    March 01, 2020 - These drugs have been studied for off-label use in several conditions. … 84 published studies on atypical antipsychotics and found that the most common off-label uses of the drugs … Sub-Question 2: How do atypical antipsychotic medications compare with other drugs, including first … How do they compare within the class and with other drugs used for the conditions? … across condition, and then compared within the class and with other drugs used for the conditions.

45. Diabetes Medications for Adults with Type 2 Diabetes: An Update | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/diabetes-update-2015/research
    December 01, 2019 - We searched Drugs@FDA and ClinicalTrials.gov for unpublished data. … SGLT-2] inhibitors) or metformin-based combination therapy (metformin plus one of these monotherapy drugs … Gastrointestinal adverse events were higher with metformin than other drugs except GLP-1 agonists, which … SGLT-2 inhibitors increased the risk of genital mycotic infections over other drugs.

46. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Results The table below lists the single topic for which (1) preliminary phase III data for drugs (or … Frustratingly, an unusually high percentage of investigational drugs have not met primary endpoints

47. FRN 35 - Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
    April 01, 2013 - Topiramate and propranolol decreased use of drugs for acute migraine attacks. … among approved drugs. … Approved drugs were more effective than off-label drugs except for the angiotensin II receptor blocker … or approved versus off-label drugs. … or approved versus off label drugs.

48. Treatments for Seasonal Allergic Rhinitis | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/allergy-seasonal/research
    December 01, 2019 - We sought to compare the following classes of drugs: oral and nasal antihistamines and decongestants; … Inclusion was limited to studies that reported an outcome of interest and directly compared drugs of … Across all comparisons, 20 of 39 drugs FDA approved for the treatment of SAR were studied. … Conclusions were limited by (1) lack of comparative evidence for all drugs within each class and (2)

49. Ced -Appendix-2 (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
    October 12, 2022 - Drugs and devices that are subject to CED should qualify for Medicare transitional pass-through status … Application of CED to on-label uses of drugs and biologicals restricts patient access. … Caution against the broad use of CED for on-label uses of drugs and biologics that have gone through … Ban CED for drugs with accelerated approval. … Recommends that on-label uses of drugs and biologicals be excluded from CED restrictions.

50. Evidence Report on the (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
    December 15, 2010 - specific dietary supplements (when compared to cardiovascular drugs alone or cardiovascular drugs and … Classes of commonly used cardiovascular drugs to be considered (excluding drugs used exclusively for … Analytic Framework for Dietary Supplement Use in Adults Taking Cardiovascular Drugs. … Drugs Aging 2009;26(Suppl 1):41-51. 4. Garner JB. … Drugs 2009;69:1777-98. 7. Miller KL, Liebowitz RS, Newby LK.

51. Migraine in Children: Preventive Pharmacologic Treatments | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/migraine-prevention/research
    December 01, 2019 - percent, reduction in migraine-related disability, and improvement in quality of life with off-label drugs … (No preventive drugs were approved in children.) … Also eligible were studies that compared drugs with nonpharmacologic interventions or drug management … Long-term preventive benefits are unknown both for drugs and nonpharmacologic interventions. … Future randomized trials of drugs with favorable benefits-to-harms ratio in adults are needed to identify

52. Dietary Supplements in Adults Taking Cardiovascular Drugs | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/dietary-supplements
    March 01, 2021 - SHARE: Dietary Supplements in Adults Taking Cardiovascular Drugs … Internet Citation: Dietary Supplements in Adults Taking Cardiovascular Drugs

53. S5 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/s5.pdf
    October 01, 2007 - The advent of Medicare Part D for outpatient prescription drugs has drawn significant attention to the … or outcome misclassification), random er- ror, confounding by clinical conditions, indications for drugs … , both alone and in comparison across drugs. … Assessment of adherence to and persistence on disease-modifying antirheumatic drugs (DMARDs) in patients … Comparison of meta- analytic results of indirect, direct, and combined comparisons of drugs for chronic

54. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0264_01-14-2008.pdf
    January 01, 2008 - Summary: The nominator questions the comparative effectiveness of disease-modifying antirheumatic drugs … idiopathic arthritis Intervention(s): Corticosteroids; Synthetic disease-modifying anti-rheumatic drugs … intramuscular gold); biologic DMARDs (i.e., etanercept, infliximab, adalimumab, anakinra) Excluded drugs … penicillamine (toxicity), oral gold (marginal efficacy), chloroquine and hydroxychloroquine (antimalarial drugs

55. Migraine-Prevention Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine-prevention_executive.pdf
    June 01, 2013 - , pediatricians prescribe drugs approved for adults or off- label drugs (approved for clinical conditions … Off-Label Pharmacologic Agents: Antiepileptic Drugs Topiramate. … Two small RCTs compared drugs with active nonpharmacologic treatments. … No studies compared combined treatments for migraine prevention with drugs alone. … Drugs for preventing migraine headaches in children.

56. Medicare Prescription Drug Coverage | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/medicare-prescription-drug-coverage
    November 17, 2014 - It's insurance that helps people pay for prescription drugs. … You have to pay part of the cost of prescription drugs. … Toolkit Research Report April 5, 2012 Data Points #9: Utilization of antidiabetic drugs

57. Horizon Scanning_Rapid Cost Analyses of Selected Potential High-Impact Intervention Reports (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
    January 01, 2015 - When considering categories of these interventions, such as drugs, devices, and procedures, new pharmaceuticals … that new pharmaceuticals/biotechnologies and new off-label uses of existing pharmaceuticals constitute … New Era of High-Cost Pharmaceuticals The proportion of costs attributable to new specialty pharmaceuticals … Although anti-obesity drugs are not part of the high-cost paradigm seen with specialty pharmaceuticals … The demand for new antiobesity drugs has been addressed in large part by three new oral drugs approved

58. Treatment of Atrial Fibrillation | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/atrial-fibrillation/research
    December 01, 2019 - Results Our review included 182 articles (148 unique studies): 14 studies relevant to rate-control drugs … , 3 relevant to strict versus lenient rate control, 6 relevant to rate-control procedures versus drugs … in patients for whom initial pharmacotherapy was ineffective, 42 relevant to antiarrhythmic drugs and … electrical cardioversion for conversion to sinus rhythm, 83 relevant to rhythm-control procedures and drugs … review found high strength of evidence supporting pulmonary vein isolation (PVI) versus antiarrhythmic drugs

59. The Incident User Design in Comparative Effectiveness Research | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/incident-user-design/research
    August 01, 2019 - coronary heart disease events among patients using COX-2 selective non-steroidal anti-inflammatory drugs … For older drugs, a 365-day window may identify patients starting a new episode of therapy, but not … Most of these patients used other disease-modifying antirheumatic drugs (DMARDs) and have now switched … If newer drugs were started more recently, the newer drugs may appear safer than older drugs because … COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease.

60. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia_hi_impact.pdf
    January 01, 2012 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … interventions expected to be within 0 to 4 years of potential diffusion (e.g., in phase III trials for pharmaceuticals … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … The search is on for ways to definitively diagnose AD and for drugs, biologics, and alternative or