-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
November 01, 2017 - characteristics
(e.g., age, type and dose of opioid involved in overdose,
or involvement of other drugs … in overdose, response
to naloxone (e.g., based on Glasgow Coma Scale score),
other substances and drugs … Amphastar Pharmaceuticals. FDA Advisory Committee Briefing
Materials. … Amphastar Pharmaceuticals. … opioide overdose 2016. http://www.fda.gov/downloads/
AdvisoryCommittees/CommitteesMeetingMaterials/Drugs
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effectivehealthcare-admin.ahrq.gov/about
February 01, 2021 - by providing the best available evidence on the outcomes, benefits and harms, and appropriateness of drugs
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effectivehealthcare-admin.ahrq.gov/products/rheumatoid-arthritis-medicine-1/research
March 30, 2009 - Annual age-specific utilization of DMARDs, glucocorticoids, non-steroidal anti-inflammatory drugs (NSAIDs … rheumatoid arthritis, disease modifying anti-rheumatic drugs, epidemiology. … Introduction
The treatment of rheumatoid arthritis (RA) with disease modifying anti-rheumatic drugs … Interestingly, about 10% of patients were not using any study drugs on the index dates. … The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis from
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effectivehealthcare-admin.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1412.pdf
December 22, 2014 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Telaprevir’s manufacturer, Vertex Pharmaceuticals, withdrew the
drug from the market in September 2014 … Viekira Pak: The Viekira Pak (AbbVie, North Chicago, IL, and Enanta Pharmaceuticals,
Inc., Watertown … In 2013, the plan spent $377 million for pharmaceuticals for all of its 600,000 members.
7
Oregon … Cambridge (MA):
Vertex Pharmaceuticals; 2011 May. 23 p.
3. Ferenci P.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1412.pdf
February 01, 2015 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Results
The table below lists the two topics for which (1) preliminary phase III data for drugs were … Repurposing diabetes
drugs for brain insulin resistance in Alzheimer
disease. … CNS Drugs. 2014
Dec;28(12):1185-9. … CNS Drugs. 2013 Jul;27(7):505-14.
Also available: http://dx.doi.org/10.1007/s40263-
013-0076-8.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-appendix-a.pdf
September 26, 2023 - alternative medicine/
12 exp Dietary Supplements/
13 exp Integrative Medicine/
14 Hallucinogenic Drugs … "dialectical behavioural therap*" or Digital or dimethyltryptamine or DMT or doximity or
drug or drugs … OR "dialectical behavioural therap*" OR Digital OR
dimethyltryptamine OR DMT OR doximity OR drug OR drugs
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effectivehealthcare-admin.ahrq.gov/products/nonopioid-chronic-pain/protocol
March 01, 2019 - most common forms of pharmacologic treatment for pain include opioids, nonsteroidal anti-inflammatory drugs … (NSAIDs), acetaminophen, topical formulations of drugs such as lidocaine, and other drugs such as antiseizure … Interventions:
Oral pharmacologic agents: nonsteroidal anti-inflammatory drugs, acetaminophen, muscle … including topiramate, lamotrigine, levetiracetam, phenytoin, valproic acid, zonisamide, tiagabine
Drugs … Supplemental Evidence And Data for Systematic review (SEADS): Manufacturers of included drugs will be
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - Oral DMARDs
Anti-‐tumor
necrosis
factor
drugs
vs.
… Oral DMARDs
Anti-tumor necrosis factor drugs vs. … Oral DMARDs
Anti-tumor necrosis factor drugs vs. … Oral DMARDs
Anti-tumor necrosis factor drugs vs. … Oral DMARDs
Anti-tumor necrosis factor drugs vs.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - Oral DMARDs
Anti-‐tumor
necrosis
factor
drugs
vs.
… Oral DMARDs
Anti-tumor necrosis factor drugs vs. … Oral DMARDs
Anti-tumor necrosis factor drugs vs. … Oral DMARDs
Anti-tumor necrosis factor drugs vs. … Oral DMARDs
Anti-tumor necrosis factor drugs vs.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/s131.pdf
October 01, 2007 - Patients With the Same Treatment Indication:
“Alternative Drug Users”
Selecting comparison drugs that … have the same per-
ceived medical indication for head-to-head comparisons of
active drugs will reduce … In studies of the effectiveness of drugs, it is question-
able whether to include patients who have a … In routine care, adherence to drugs is unfortunately
substantially lower than in RCTs. … Selective prescribing can lead
to over-estimation of the benefits of lipid-lowering drugs.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
March 01, 2013 - Study
did not compare specific drugs. … Association between disease-modifying
antirheumatic drugs and diabetes risk in
patients with rheumatoid … Association between systemic antipsoriatic
drugs and cardiovascular risk in patients
with psoriasis … Evidence Table
Author, Year Study Design Study name Drugs Year
conducted
N,
Population
F/U … Author, Year Study Design Study name Drugs Year
conducted
N,
Population
F/U
Length
Efficacy
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
November 01, 2023 - update for baclofen and 7 new trials for topiramate, and a small
number of studies reported on some drugs … With the help of our technical expert panel, we
limited drugs with off-label uses to those that are … Therefore,
some drugs reviewed as emerging therapies and some only available outside the United
States … In terms of results, our assessment of the effects of those drugs with
Food and Drug Administration
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effectivehealthcare-admin.ahrq.gov/products/back-pain-treatment/clinician
November 15, 2016 - Pharmacological interventions: Nonsteroidal anti- inflammatory drugs (NSAIDs) may be effective in treating … Table 5 : FDA Black Box Warnings for Drugs Used To Treat Low Back Pain
Drugs
FDA Black Box Warning … immediate-release)
Misuse, abuse, addiction, overdose, and death
Nonsteroidal anti-inflammatory drugs … Furthermore, several of the trials evaluating antidepressants were funded by the manufacturers of the drugs
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effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1506.pdf
June 01, 2015 - health care sector, horizon
scanning pertains to identification of new (and new uses of existing) pharmaceuticals … Information is compiled for expert comment on topics at a granular
level (i.e., similar drugs in the … Results
The table below lists the three topics for which (1) preliminary phase III data for drugs or … Safety of antiobesity drugs. Ther Adv Drug Saf.
2013;4(4):171-81. … Anti-
obesity drugs: Past, present and future. Dis Model
Mech. 2012 Sep;5(5):621-6.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-evidence-summary.pdf
August 01, 2018 - Some drugs aim to reduce symptoms associated with acute
manic or mixed mania/depression episodes, some … For drugs not approved for BD,
paliperidone also improved acute mania compared to
placebo (low-strength … a number of
observational studies being excluded, including those
that looked at broad classes of drugs … , or individual drugs
across broad populations. … However,
none of the drugs reached MID.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/s81.pdf
October 01, 2007 - Nurses coded causative drugs
into major classes. … Fewer
classes of drugs commonly cause bleeding. … to these mechanisms are warfa-
rins, heparins, antiplatelet agents, nonsteroidal anti-inflam-
matory drugs … We derived a list of codes reflecting indications where
guidelines17,18 dictate the use of drugs that … Development of models was greatly facilitated by focusing
on the group estimated to be exposed to drugs
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
April 01, 2012 - Coordinating Council for Comparative Effectiveness Research,
AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices,
procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar
drugs in the … The table below lists the three topics for which (1) preliminary phase III were
available for drugs … Impact
Interventions Report, we aggregated related topics for summary and discussion (e.g., individual drugs
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
June 29, 2019 - many older adults are
unable to tolerate non-opioid analgesics (e.g., non-steroidal anti-inflammatory drugs … Cyclooxygenase-2
selectivity of non-steroidal anti-inflammatory drugs and the risk of myocardial infarction … Do selective cyclo-oxygenase-2
inhibitors and traditional non-steroidal anti-inflammatory drugs increase … A metaanalysis of severe upper
gastrointestinal complications of nonsteroidal antiinflammatory drugs … Meta-analysis of dyspepsia and
nonsteroidal antiinflammatory drugs.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - Some opioids may be less
effective than other drugs. … Key Messages
• Opioids are probably less effective than
nonsteroidal anti-inflammatory drugs (NSAIDs … by the Centers for Disease
Control and Prevention, evaluates the benefits and
harms of nonopioid drugs … Key Messages
As initial therapy in the prehospital setting:
• Nonsteroidal anti-inflammatory drugs … Key Messages
As initial therapy in the prehospital setting:
Nonsteroidal anti-inflammatory drugs
-
effectivehealthcare-admin.ahrq.gov/products/opioids-older-adults/protocol
August 16, 2019 - many older adults are unable to tolerate non-opioid analgesics (e.g., non-steroidal anti-inflammatory drugs … Cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs and the risk of myocardial infarction … Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase … A metaanalysis of severe upper gastrointestinal complications of nonsteroidal antiinflammatory drugs. … Meta-analysis of dyspepsia and nonsteroidal antiinflammatory drugs.