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Showing results for "drugs".

21. Chicago-Area DEcIDE Center (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
    May 01, 2009 - years (based from 12/31/06) were coded as 1.0, drugs approved between 4-13 years as 0.5, and drugs … Bayesian approaches to the value of information: implications for the regulation of new pharmaceuticals … c The Drug Safety index value is coded as 1 for drugs with a black box warning, 0.5 for drugs that had … drugs that entered 4 to 13 years ago, and zero for drugs that entered more than 13 years ago and zero … the drugs shifted from the top tier).

22. Disease-Modifying Antirheumatic Drugs (DMARDs) in Children With Juvenile Idiopathic Arthritis (JIA) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/juvenile-arthritis-dmards/research
    December 01, 2019 - Home Evidence Reports Disease-Modifying Antirheumatic Drugs … SHARE: Disease-Modifying Antirheumatic Drugs … Structured Abstract Objectives To summarize the benefits and harms of disease-modifying antirheumatic drugs … DMARDs across categories of JIA, and registries are needed to better understand the risks of these drugs … Project Timeline Disease-Modifying Antirheumatic Drugs (DMARDs) in Children With Juvenile Idiopathic

23. Dietary Supplements in Adults Taking Cardiovascular Drugs | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/dietary-supplements/research
    December 01, 2019 - Evidence Reports Dietary Supplements in Adults Taking Cardiovascular Drugs … SHARE: Dietary Supplements in Adults Taking Cardiovascular Drugs … cardiovascular drug pharmacokinetics of coadministration of dietary supplements with cardiovascular drugs … evidence regarding variability among subgroups, and of statistical interactions between supplements and drugs … Project Timeline Dietary Supplements in Adults Taking Cardiovascular Drugs Aug 16, 2010

24. Addressing Knowledge Gaps in Type 2 Diabetes Therapeutics: Comparative Effectiveness and Safety of Oral Antidiabetic Drugs | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/diabetes-oral-drugs-safety-knowledge-gaps/research
    November 01, 2017 - Knowledge Gaps in Type 2 Diabetes Therapeutics: Comparative Effectiveness and Safety of Oral Antidiabetic Drugs … Knowledge Gaps in Type 2 Diabetes Therapeutics: Comparative Effectiveness and Safety of Oral Antidiabetic Drugs … Comparative effectiveness of incident oral antidiabetic drugs on kidney function. … Knowledge Gaps in Type 2 Diabetes Therapeutics: Comparative Effectiveness and Safety of Oral Antidiabetic Drugs … https://effectivehealthcare.ahrq.gov/products/diabetes-oral-drugs-safety-knowledge-gaps/research

25. Migraine-Adults-Executive-130408 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
    April 01, 2013 - or approved versus off-label drugs. … Discussion All approved drugs, some off-label beta blockers, and the angiotensin inhibiting drugs were … The relative effect size of drugs was moderate: drugs would result in to 200 to 400 cases of clinical … or approved versus off-label drugs. … Modeling choice behavior for new pharmaceutical products.

26. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/high-risk-drugs-protocol.pdf
    July 27, 2023 - Center Rapid Response Protocol Project Title: Making Healthcare Safer IV: Protocols for High-Risk Drugs … The “Protocols for High-Risk Drugs: Reducing Adverse Drug Events Related to Anticoagulants” as a patient … High-Alert Drugs: Patient Safety Practices for Intravenous Anticoagulants.

27. Report of a Pilot Project: Rapid Cost Analyses of Selected Potential High-Impact Intervention Reports | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/horizon-scan/research-2015
    November 01, 2017 - Health care horizon scanning is an activity undertaken to identify technological and system innovations (pharmaceuticals … New drugs for treating one disease—direct-acting oral antivirals for interferon-free treatment of hepatitis … When considering categories of these interventions, such as drugs, devices, and procedures, new pharmaceuticals … /biotechnologies and new off-label uses of existing pharmaceuticals constituted about 60 percent of estimated … annual spend of more than $1 billion each totaled $35 billion in estimated spend (including the new oral drugs

28. #14 SUBSTANCE ABUSE (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/substanceabuse_hi_impact.pdf
    January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Prescription drugs: abuse and addiction. [internet]. … Titan Pharmaceuticals provides probuphine update after meeting with U.S.

29. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0128_07-01-2009.pdf
    January 01, 2009 - Results of Topic Selection Process & Next Steps  Generic versus brand name antiepileptic drugs … come out against the substitution of „A‟ rated generics, and neurologists use a large amount of brand drugs … In addition, many states include these drugs in their narrow therapeutic index laws. … : All patients with seizures stratified by seizure type Intervention(s): Brand name antiepileptic drugs … Comparator(s): Generic antiepileptic drugs Outcome(s): Seizure control, emergency department visits

30. White Paper: Enhancing Systematic Review Methods by Incorporating Unpublished Drug Trials (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
    December 01, 2024 - Visit the Drugs@FDA website and navigate to the approval history. c. … Check Drugs@FDA. … Drug maturity Not-so-new drugs Relatively new drugs Older drugs are more likely to have missing and … We focused on three psychiatric drugs. … Regulatory agencies hold the key to improving Cochrane reviews of drugs.

31. Obesity (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
    April 17, 2012 - Antiobesity Drugs for Treatment of Obesity  Key Facts: Three drugs are in phase III development for … In December 2010, Arena Pharmaceuticals announced a plan to resubmit the lorcaserin NDA by the end … Arena Pharmaceuticals. Lorcaserin hydrochloride. Drugs Future 2007;32(9):766-70. 12. … Meta-analyses of phase 3 trials show obese and overweight patients taking Arena Pharmaceuticals' … Istanbul: Arena Pharmaceuticals, Inc.; 2011 May 26 [accessed 2011 Nov 16]. [3 p].

32. Comparative Effectiveness and Safety of Analgesics for Osteoarthritis – An Update to the 2006 Report | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/osteoarthritis-pain/research-protocol
    December 01, 2019 - Patients with osteoarthritis also use over-the-counter supplements not regulated by the FDA as pharmaceuticals … In addition, efficacy and safety may vary for individual drugs within a class. … Pharmacokinetics, Indications, and Dosing of Drugs to be Included. … Non-steroidal anti-inflammatory drugs. … Non-steroidal anti-inflammatory drugs for low-back pain.

33. Nonopioid Pharmacologic Treatments for Chronic Pain | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/nonopioid-chronic-pain/research
    June 01, 2022 - Purpose of Review Evaluate the benefits and harms of nonopioid drugs in randomized … neuropathy/post-herpetic neuralgia and fibromyalgia, and small with nonsteroidal anti-inflammatory drugs … While most comparisons of drugs and doses did not identify differences, diclofenac improved pain and … Other drugs studied, including acetaminophen (osteoarthritis), capsaicin (neuropathic pain), cannabis … Withdrawal from study due to adverse events was significantly increased with nonopioid drugs, with the

34. Disposition of Comments for Migraine in Adults: Preventive Pharmacologic Treatments (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
    April 18, 2013 - We did review off-label drugs available in the US. … of the outcomes with different drugs. … The large number of off label drugs may reflects the fact that approved drugs have undesirable balance … drugs from different classes. … , as well as individual drugs.

35. Communicating Harms and Benefits of Prescription Drugs to Healthcare Consumers (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/communicating_risk_hickam.ppt
    December 01, 2006 - Communicating Harms and Benefits of Prescription Drugs to Healthcare Consumers Communicating Harms … and Benefits of Prescription Drugs to Healthcare Consumers John M. … Center Agency for Healthcare Research and Quality Effective Health Care Program 1.bin Themes Drugs

36. Newer Medications for Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: A Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/prostatic-hyperplasia-medications/research
    December 01, 2019 - Abstract Objective To assess the efficacy, comparative effectiveness, and adverse effects of newer drugs … We identified trials testing other drugs (mirabegron, oxybutynin, darifenacin, sildenafil, and vardenafil … Conclusions Several drugs newly used for LUTS attributed to BPH, alone or in combination with older … outcomes were similar to older AB monotherapy and adverse effects were often higher with the newly used drugs

37. Medicines | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/medicines
    December 06, 2016 - Even safe drugs can cause unwanted side effects or interactions with food or other medicines you may … Systematic Review Archived April 30, 2012 Dietary Supplements in Adults Taking Cardiovascular Drugs … Effectiveness of Dietary Supplement Versus No Dietary Supplement Use in Adults Taking Cardiovascular Drugs … Data White Paper September 30, 2006 Communicating Harms and Benefits of Prescription Drugs

38. Drug Abuse | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/drug-abuse
    April 01, 2021 - Abused drugs include Methamphetamine Anabolic steroids Club drugs Cocaine Heroin Inhalants … Marijuana Prescription drugs , including opioids Drug abuse also plays a role in many major

39. Evaluation of Effectiveness and Safety of Antiepileptic Medications in Patients with Epilepsy | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/epilepsy-medicine/research-protocol
    December 01, 2019 - Antiepileptic Drugs . Fourth ed. New York, Raven Press; 1995. p. 799-806. … Antiepileptic Drugs . Philadelphia, Lippincott Williams & Wilkins; 2002. p. 901-5. … Therapeutic equivalence of generic drugs letter to health practitioners. … drugs, generic/ therapeutic equivalency/ (brand adj name).mp. … drugs, generic/ therapeutic equivalency/ (brand adj name).mp.

40. S96 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/s96.pdf
    October 01, 2007 - Of 10,383 reports in 2004, 100% listed patient age, sex, and disposition; 98% listed the implicated drugs … provides detailed and timely infor- mation on outpatient ADEs treated in EDs and identifies specific drugs … Deiden- tified data are then forwarded to CDC where all case reports involving pharmaceutical products … drugs are suspected, this information may be added as a free-text description. … Risk assessment of drugs, biologics and therapeutic devices: present and future issues.