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Total Results: 2,208 records

Showing results for "drugs".

181. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - they are based on insufficient or low evidence and the broad categorization into newer and older drugs … Comparative safety of antiepileptic drugs during pregnancy. Neurology. 2012 May 22;78(21):1692-9. … Gastrointestinal adverse effects of antiepileptic drugs in intractable epileptic patients. … Assessing bioequivalence of generic antiepilepsy drugs. … Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.

182. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - they are based on insufficient or low evidence and the broad categorization into newer and older drugs … Comparative safety of antiepileptic drugs during pregnancy. Neurology. 2012 May 22;78(21):1692-9. … Gastrointestinal adverse effects of antiepileptic drugs in intractable epileptic patients. … Assessing bioequivalence of generic antiepilepsy drugs. … Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.

183. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … Combination phentermine-topiramate (Qsymia®, Vivus, Inc., Mountain View, CA)  Lorcaserin (Belviq®, Arena Pharmaceuticals … Phentermine-topiramate is a controlled-release formulation of two separate FDA-approved drugs. … Arena Pharmaceuticals and Eisai announce FDA approval of Belviq (lorcaserin HCl) for chronic weight … San Diego (CA): Arena Pharmaceuticals; 2012 Jun 27 [accessed 2012 Jul 5]. [4 p].

184. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
     January 28, 2016 - health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … unmet need for new antiviral drugs for treating chronic HCV infection. … Manufacturers with the most advanced candidates include the Janssen Pharmaceuticals unit of Johnson … It excluded 72 drugs in 2015, including Harvoni, Sovaldi, and Olysio. … Available: http://blue.regence.com/trgmedpol/drugs/dru366 .pdf. 91.

185. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
     March 09, 2010 - Center Systematic Review Protocol Project Title: The Effectiveness of Disease-Modifying Antirheumatic Drugs … Therapy with the so-called disease-modifying anti-rheumatic drugs (DMARDs) has become an increasingly … These drugs, which operate through a number of different mechanisms (see Table 2), share the common … effect of limiting radiologic progression of disease.4 Although these drugs can dramatically improve … There are many unanswered questions about the safety and effectiveness of these drugs, especially for

186. Atrial-Fibrillation Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_executive.pdf
     June 01, 2013 - to be similar enough to be grouped together and all beta blocker drugs to be similar enough to be … • Although based on limited studies and use of different drugs for pretreatment, current evidence … Procedural therapies: • Transcatheter PVI versus antiarrhythmic drugs – Based on eight RCTs (five … For KQ 3, our findings underscore the need for additional studies to compare rate-control drugs with … of the comparative safety and effectiveness of these different drugs and procedures.

187. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/11_pepticulcer_potential_high_impact_june_2012.pdf
     January 01, 2012 - For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Results The table below lists the four topics for which (1) preliminary phase III data for drugs and … Most research activity in this priority area is focusing on drugs and biologics for irritable bowel … Curr Opin Investig Drugs 2001 Apr;2(4):505-9. PMID: 11566007 43. Tappenden K, Edelman J.

188. Evaluation and Treatment of Tinnitus: Comparative Effectiveness | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/tinnitus/research
     December 01, 2019 - pharmacological interventions, SOE is low for improvements to subjective loudness from neurotransmitter drugs … versus placebo; insufficient for antidepressants, other drugs, and food supplements with respect to

189. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … ALZT-OP1's developers hypothesize that administering these drugs in concert will relieve symptoms of

190. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
     September 01, 2011 - This review did not evaluate pharmacokinetics of the drugs. … into the text of the report for methotrexate or the other drugs. … I would also indicate the drugs that you are referring to. … So a moderate SoE for symptoms only applies to a few drugs not the entire class. … Specific drugs are described in the text.

191. Noninvasive Treatments for Low Back Pain: Current State of the Evidence | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/back-pain-treatment/clinician
     June 01, 2021 - Pharmacological interventions: Nonsteroidal anti- inflammatory drugs (NSAIDs) may be effective in treating … Table 5 : FDA Black Box Warnings for Drugs Used To Treat Low Back Pain Drugs FDA Black Box Warning … immediate-release) Misuse, abuse, addiction, overdose, and death Nonsteroidal anti-inflammatory drugs … Furthermore, several of the trials evaluating antidepressants were funded by the manufacturers of the drugs

192. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
     January 01, 2012 - Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2011 May 12 [accessed 2011 Jul 15]. [2 p]. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2011 Oct 31 [accessed 2011 Nov 11]. [4 p]. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2012 Oct 16 [accessed 2012 Oct 16]. [3 p]. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2012 Jan 31 [accessed 2012 Jun 5]. [2 p]. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2011 Dec 1 [accessed 2012 Jan 26]. [2 p].

193. Tinnitus Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
     August 01, 2013 - Five articles12-16 investigated antidepressant drugs versus placebo. … These drugs included sertraline,12,13 paroxetine,14 trazodone,15 and nortriptyline.16 Dosage levels … The neurotransmitter drugs were gabapentin,17 baclofen,18 alprazolam,19 and acamprosate.20,21 Three … studies investigated other drugs, including methylprednisolone versus placebo,22 vardenafil versus … , food supplements, and other drugs Evidence suggests that neurotransmitter drugs showed improvement

194. CER 218 Disposition of Comments: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
     April 23, 2019 - Table 5) Comment: Table 4 defines the interventions to be included in this systematic review as “Drugs … to determine whether these harms were associated with long-term treatment with these osteoporosis drugs … Class-Specific Harms of Drugs Used for Osteoporosis Treatment has several important errors. … to determine whether these harms were associated with long-term treatment with these osteoporosis drugs … Results Public Commenter #1 (Rafael Pirtillo Ferman -Altietus College) Drugs still working Thank

195. Introduction (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-1_research.pdf
     February 01, 2009 - Annual age-specific utilization of DMARDs, glucocorticoids, non-steroidal anti- inflammatory drugs (NSAIDs … rheumatoid arthritis, disease modifying anti-rheumatic drugs, epidemiology Effective Health Care … 8 Introduction The treatment of rheumatoid arthritis (RA) with disease modifying anti-rheumatic drugs … Interestingly, about 10% of patients were not using any study drugs on the index dates. … The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis

196. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
     July 09, 2013 - In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … The search is on for ways to definitively diagnose AD and for drugs, biologics, and alternative or … The Horizon Scanning System is tracking several drugs in late-phase development. … Peripheral and Central Nervous System Drugs Advisory Committee.

197. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
     September 01, 2011 - A few years ago, these drugs were all off label for autism, depression, augmentation of depression, … Actually, we refrained from doing pooled analyses across, drugs in response to reviewers comments … So, we think the report is suitably restrained on drawing conclusions across drugs. … As these drugs are approved for use in MDD, rationale for inclusion of the data in the report should … The drugs are still included in the chart for comparative purposes.

198. rheumatoid-arthritis-medicine-update-protocol-170515 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
     May 15, 2017 - Newly approved drugs and those under review by the FDA are described in Section B (see Table 1) above … Few data are available on efficacy for these drugs; even less is known about how their effectiveness … and harms compared with that of existing drugs. … What has Changed New drugs: Additional clinical trials of three biosimilar drugs and a tsDMARD (an … Clinical trials of new drugs for the treatment of rheumatoid arthritis: focus on early disease.

199. Disposition of Comments Report for Biologic and Nonbiologic Systemic Agents and Phottherapy for Treatment of Chronic Plaque Psoriasis (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
     November 27, 2012 - , just as non- biologics for psoriasis are not considered a “class” of drugs either. … We have added the terms biologic and nonbiologic to our glossary with a listing of the drugs which … Suggest specifically mentioning the nonbiologic drugs. Thank you for this suggestion. … Are they naïve to both drugs (mtx, adalimumab, etanercept?) Thank you for this suggestion. … More information about each of the drugs and phototherapy would be helpful.

200. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
     March 28, 2019 - We have listed the included drugs and also how they were decided upon. … Only studies that evaluated one of the drugs in Table 1 were eligible. … These drugs could have been in comparison to a TCA. … to meaningfully compare drugs in this class and assess their relative harms. … Thus, it is incorrect to claim that drugs does not cause adverse events based on public data.