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Total Results: 2,204 records

Showing results for "drugs".

181. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - they are based on insufficient or low evidence and the broad categorization into newer and older drugs … Comparative safety of antiepileptic drugs during pregnancy. Neurology. 2012 May 22;78(21):1692-9. … Gastrointestinal adverse effects of antiepileptic drugs in intractable epileptic patients. … Assessing bioequivalence of generic antiepilepsy drugs. … Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.

182. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - they are based on insufficient or low evidence and the broad categorization into newer and older drugs … Comparative safety of antiepileptic drugs during pregnancy. Neurology. 2012 May 22;78(21):1692-9. … Gastrointestinal adverse effects of antiepileptic drugs in intractable epileptic patients. … Assessing bioequivalence of generic antiepilepsy drugs. … Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.

183. Observed Association Between Antidepressant Use and Pneumonia Risk Was Confounded by Comorbidity Measures (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antidepressants-seniors-pneumonia_research.pdf
     May 01, 2008 - period preceding a hospitalization for depression [7], leading to the hypothesis that antidepressant drugs … Most diagnoses, drugs prescribed ever in the past, and currently prescribed drugs examined were substantially … range of potential signals to be further tested, did not measure actual exposure to antidepressant drugs … Risk of community- acquired pneumonia and use of gastric acid- suppressive drugs. … 536 (4.5) 636 (1.3) 2.24 (1.97 to 2.54) suicidal ideation 7 (0.1) 19 (0.0) 1.98 (0.78 to 5.07) drugs

184. Noninvasive Treatments for Low Back Pain: Current State of the Evidence (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
     November 01, 2016 - . �� Pharmacological interventions: Nonsteroidal anti- inflammatory drugs (NSAIDs) may be effective … Furthermore, several of the trials evaluating antidepressants were funded by the manufacturers of the drugs … Drugs FDA Black Box Warning Opioids (immediate-release) ��Misuse, abuse, addiction, overdose, and … death Nonsteroidal anti-inflammatory drugs ��Cardiovascular thrombotic events, including myocardial … can be fatal Antidepressants �� Suicidal thoughts and behaviors Table 5: FDA Black Box Warnings for Drugs

185. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
     March 09, 2010 - Center Systematic Review Protocol Project Title: The Effectiveness of Disease-Modifying Antirheumatic Drugs … Therapy with the so-called disease-modifying anti-rheumatic drugs (DMARDs) has become an increasingly … These drugs, which operate through a number of different mechanisms (see Table 2), share the common … effect of limiting radiologic progression of disease.4 Although these drugs can dramatically improve … There are many unanswered questions about the safety and effectiveness of these drugs, especially for

186. Atrial-Fibrillation Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_executive.pdf
     June 01, 2013 - to be similar enough to be grouped together and all beta blocker drugs to be similar enough to be … • Although based on limited studies and use of different drugs for pretreatment, current evidence … Procedural therapies: • Transcatheter PVI versus antiarrhythmic drugs – Based on eight RCTs (five … For KQ 3, our findings underscore the need for additional studies to compare rate-control drugs with … of the comparative safety and effectiveness of these different drugs and procedures.

187. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … health care sector, horizon scanning pertains to identification of new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … ALZT-OP1's developers hypothesize that administering these drugs in concert will relieve symptoms of

188. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
     January 01, 2012 - Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2011 May 12 [accessed 2011 Jul 15]. [2 p]. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2011 Oct 31 [accessed 2011 Nov 11]. [4 p]. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2012 Oct 16 [accessed 2012 Oct 16]. [3 p]. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2012 Jan 31 [accessed 2012 Jun 5]. [2 p]. … Bedminster (NJ): NPS Pharmaceuticals, Inc.; 2011 Dec 1 [accessed 2012 Jan 26]. [2 p].

189. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
     September 01, 2011 - This review did not evaluate pharmacokinetics of the drugs. … into the text of the report for methotrexate or the other drugs. … I would also indicate the drugs that you are referring to. … So a moderate SoE for symptoms only applies to a few drugs not the entire class. … Specific drugs are described in the text.

190. Evaluation and Treatment of Tinnitus: Comparative Effectiveness | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/tinnitus/research
     December 01, 2019 - pharmacological interventions, SOE is low for improvements to subjective loudness from neurotransmitter drugs … versus placebo; insufficient for antidepressants, other drugs, and food supplements with respect to

191. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Vertex Pharmaceuticals Incorporated. … Vertex Pharmaceuticals Incorporated.

192. Noninvasive Treatments for Low Back Pain: Current State of the Evidence | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/back-pain-treatment/clinician
     June 01, 2021 - Pharmacological interventions: Nonsteroidal anti- inflammatory drugs (NSAIDs) may be effective in treating … Table 5 : FDA Black Box Warnings for Drugs Used To Treat Low Back Pain Drugs FDA Black Box Warning … immediate-release) Misuse, abuse, addiction, overdose, and death Nonsteroidal anti-inflammatory drugs … Furthermore, several of the trials evaluating antidepressants were funded by the manufacturers of the drugs

193. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
     July 09, 2013 - In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … The search is on for ways to definitively diagnose AD and for drugs, biologics, and alternative or … The Horizon Scanning System is tracking several drugs in late-phase development. … Peripheral and Central Nervous System Drugs Advisory Committee.

194. Tinnitus Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
     August 01, 2013 - Five articles12-16 investigated antidepressant drugs versus placebo. … These drugs included sertraline,12,13 paroxetine,14 trazodone,15 and nortriptyline.16 Dosage levels … The neurotransmitter drugs were gabapentin,17 baclofen,18 alprazolam,19 and acamprosate.20,21 Three … studies investigated other drugs, including methylprednisolone versus placebo,22 vardenafil versus … , food supplements, and other drugs Evidence suggests that neurotransmitter drugs showed improvement

195. Introduction (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-1_research.pdf
     February 01, 2009 - Annual age-specific utilization of DMARDs, glucocorticoids, non-steroidal anti- inflammatory drugs (NSAIDs … rheumatoid arthritis, disease modifying anti-rheumatic drugs, epidemiology Effective Health Care … 8 Introduction The treatment of rheumatoid arthritis (RA) with disease modifying anti-rheumatic drugs … Interestingly, about 10% of patients were not using any study drugs on the index dates. … The changing use of disease-modifying anti-rheumatic drugs in individuals with rheumatoid arthritis

196. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
     September 01, 2011 - A few years ago, these drugs were all off label for autism, depression, augmentation of depression, … Actually, we refrained from doing pooled analyses across, drugs in response to reviewers comments … So, we think the report is suitably restrained on drawing conclusions across drugs. … As these drugs are approved for use in MDD, rationale for inclusion of the data in the report should … The drugs are still included in the chart for comparative purposes.

197. rheumatoid-arthritis-medicine-update-protocol-170515 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
     May 15, 2017 - Newly approved drugs and those under review by the FDA are described in Section B (see Table 1) above … Few data are available on efficacy for these drugs; even less is known about how their effectiveness … and harms compared with that of existing drugs. … What has Changed New drugs: Additional clinical trials of three biosimilar drugs and a tsDMARD (an … Clinical trials of new drugs for the treatment of rheumatoid arthritis: focus on early disease.

198. Disposition of Comments Report for Biologic and Nonbiologic Systemic Agents and Phottherapy for Treatment of Chronic Plaque Psoriasis (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
     November 27, 2012 - , just as non- biologics for psoriasis are not considered a “class” of drugs either. … We have added the terms biologic and nonbiologic to our glossary with a listing of the drugs which … Suggest specifically mentioning the nonbiologic drugs. Thank you for this suggestion. … Are they naïve to both drugs (mtx, adalimumab, etanercept?) Thank you for this suggestion. … More information about each of the drugs and phototherapy would be helpful.

199. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
     March 28, 2019 - We have listed the included drugs and also how they were decided upon. … Only studies that evaluated one of the drugs in Table 1 were eligible. … These drugs could have been in comparison to a TCA. … to meaningfully compare drugs in this class and assess their relative harms. … Thus, it is incorrect to claim that drugs does not cause adverse events based on public data.

200. Treatments for Adults with Schizophrenia: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
     September 23, 2016 - Second-Generation Antipsychotic Drugs Aripiprazole (Abilify®, Aristada™*) Asenapine (Saphris® ), … and in 2013 for 2nd versus 2nd generation drugs. … Consensus development conference on antipsychotic drugs and obesity and diabetes. … Drug Class Review of Atypical Antipsychotic Drugs; Update 3. … Drug Class Review: Second Generation Antipsychotic Drugs. Final Report - Update 4.