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Showing results for "drugs".

101. does use of generic medications for seizures result in poorer control (more ER visits and or hospitalizations than the use of brand name medications. | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/does-use-of-generic-medications-for-seizures-result-in-poorer-control-more-er-visits-and-or-hospitalizations-than-the-use-of-brand-name-medications
     November 01, 2017 - yes If yes, explain the specific technologies, devices, drugs, or interventions you would like to … come out against the substitution of "A" rated generics and neurologists use a large amount of brand drugs … In addition many states include these drugs in their narrow therapeutic index laws. … If there is in fact a difference between the therapeutic effect of these drugs then more rational and

102. The American College of Chest Physicians (ACCP) proposes to update the medical therapies section of 2007 updated publication on Medical Therapies for Pulmonary Arterial Hypertension: ACCP Evidence-Based Clinical Practice Guidelines.1 1.… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/the-american-college-of-chest-physicians-accp-proposes-to-update-the-medical-therapies-section-of-2007-updated-publication-on-medical-therapies-for-pulmonary-arterial-hypertension-accp-evidence-based-clinical-practice-guidel
     November 01, 2017 - yes If yes, explain the specific technologies, devices, drugs, or interventions you would like to … see compared: 2 new drugs have now been approved for the treatment of PAH: inhaled treprostinil … ambrisentan Comparisons should be made between these new drugs and the older ones, listed here … Side effects of various drugs include but are not limited to liver function abnormalities, elevated serum … Since the 2007 update of the medical therapies section of the 2004 guidelines, 2 new drugs have been

103. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
     May 19, 2010 - These drugs have been studied for off-label use in several conditions. … published studies on atypical antipsychotics and found that the most common off-label uses of the drugs … treatment for agitation in dementia, association between the increased risk of death and antipsychotics drugs … Sub-Question 2: How do atypical antipsychotic medications compare with other drugs, including first … How do they compare within the class and with other drugs used for the conditions?

104. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1412.pdf
     October 01, 2015 - Cambridge (MA): Vertex Pharmaceuticals, Inc.; 2011 Nov 03 [accessed 2014 Apr 10]. [4 p]. … Cambridge (MA): Vertex Pharmaceuticals, Inc.; 2010 Nov 08 [accessed 2011 Jan 04]. [1 p]. … Boston (MA): Vertex Pharmaceuticals, Inc.; 2014 Nov 05 [accessed 2014 Dec 11]. [3 p]. … Boehringer Ingelheim Pharmaceuticals, Inc. … Ridgefield (CT): Boehringer Ingelheim Pharmaceuticals, Inc.; 2014 Oct. 18 p.

105. #06 Developmental Delays ADHD, and Autism (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/06_devdelays_autism_potential_high_impact_june_2012.pdf
     January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … These drugs will likely face intense scrutiny, considering the challenges of accurately diagnosing

106. Prescription Drug Abuse | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/prescription-drug-abuse
     November 27, 2017 - Using the medicine for another purpose, such as getting high Abusing some prescription drugs can … People who abuse these drugs may not understand the risks.

107. Methods-Guidance-Reporting-Bias Methods (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-reporting-bias_methods.pdf
     November 01, 2013 - Regulatory Documents Reviews of Drugs Compared With Devices Drugs and devices are both regulated by … • Reviewers should search Drugs@FDA for information on drugs; if a search is not conducted reviewers … However, the Web site typically does not have documents related to older drugs and very new drugs. … International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals … For drugs: generic name, or temporary identifier for drugs that do not yet have a generic name; for

108. Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis – An Update of the 2007 Report | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/osteoporosis-bone-fracture/research-protocol
     March 01, 2020 - Controlled clinical trials that report fracture outcomes for one or more of the drugs of interest will … Articles of any study design that report on adherence/persistence for any of the drugs of interest will … In our search to identify clinical studies of drugs of interest to this review, we will use terms for … osteoporosis, osteopenia, low bone density, and the drugs listed in the key questions (as well as any … In our search for the key AE, we will use terms for the AE and each of the drugs of interest for this

109. Addressing Knowledge Gaps in the Treatment of Hypertension Using ACE/ARB Therapies | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/hypertension-treatment-knowledge-gaps/abstract
     December 01, 2019 - Commonly used two classes of drugs, angiotensin converting enzyme inhibitors (ACEIs) and angiotensin … actionable information for patients, physicians and policy makers to make decision in uses of these drugs

110. Dementia | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/dementia
     February 19, 2025 - Drugs are available to treat some of these diseases. … While these drugs cannot cure dementia or repair brain damage, they may improve symptoms or slow down

111. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
     December 01, 2013 - San Diego (CA): Arena Pharmaceuticals, Inc; 2010 Nov 9 [accessed 2011 Dec 16]. [3 p]. … New data from Arena Pharmaceuticals' pivotal BLOSSOM trial of lorcaserin demonstrate improvements … Washington (DC): Arena Pharmaceuticals, Inc.; 2009 Oct 27 [accessed 2011 Apr 21]. [4 p]. … San Diego (CA): Arena Pharmaceuticals; 2012 Jun 27 [accessed 2012 Jul 5]. [4 p]. … Arena Pharmaceuticals. Lorcaserin hydrochloride. Drugs Future. 2007;32(9):766-70. 78.

112. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/04_dementia_potential_high_impact_june_2012.pdf
     January 01, 2012 - In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … The search is on for ways to definitively diagnose AD and for drugs, biologics, and alternative or … Peripheral and Central Nervous System Drugs Advisory Committee.

113. Diagnosis and Treatment of Clinical Alzheimer’s-Type Dementia: Evidence Summary (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/Evidence%20Summary_1.pdf
     April 01, 2020 - Finally, although only a few prescription drugs are approved by the U.S. … – There was minimal evidence addressing whether efficacy of prescription drugs for CATD treatment … (n=454), and five that compared prescription drugs with supplements (n=258). … Two trials compared different prescription drugs (n=414). … Evidence on the efficacy and harms of CATD drugs had several limitations.

114. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/13_pulmonary_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … Vertex Pharmaceuticals Incorporated. … Vertex Pharmaceuticals Incorporated.

115. PHARMACO-EPIDEMIOLOGIC METHODS FOR A STUDY OF (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-cardiovascular-elderly_research.pdf
     February 01, 2009 - .10 Another observational study found higher mortality in those given haloperidol vs. two atypical drugs … FDA warns antipsychotic drugs may be risky for elderly. JAMA 2005;293:2462. 3. Strong C. … Using antipsychotic agents in older patients: expert consensus panel for using antipsychotic drugs … Antipsychotic drugs: prolonged QTc Interval, Torsade de Pointes, and sudden death. … Antipsychotic drugs in dementia: what should be made of the risks? JAMA 2005;294:1963-1965.

116. Urinary-Incontinence-Treatment Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
     April 01, 2012 - The absolute risk difference in continence was less than 20 percent for all drugs. … Adverse effects were common with all drugs and varied between the drugs. … Treatment discontinuation due to adverse effects of drugs is common. … Benefits and harms with drugs did not differ by individual quality criteria. … • Drugs for urgency UI demonstrated similar effectiveness.

117. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - Coordinating Council for Comparative Effectiveness Research, AHRQ is interested in innovations in drugs … In the health care sector, horizon scanning pertains to identifying new (and new uses of existing) pharmaceuticals … For purposes of horizon scanning, AHRQ’s interests are broad and encompass drugs, devices, procedures … Information is compiled for expert comment on topics at a granular level (i.e., similar drugs in the … The topic, buprenorphine implant (Probuphine,™ Titan Pharmaceuticals, Inc., South San Francisco, CA

118. Diagnosis and Comparative Effectiveness of Treatments for Urinary Incontinence in Adult Women | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/urinary-incontinence-treatment/research-protocol
     December 01, 2020 - Harms: Adverse events resulting from drugs. … Adrenergic drugs for urinary incontinence in adults. … Anticholinergic drugs versus placebo for overactive bladder syndrome in adults. … Anticholinergic drugs versus other medications for overactive bladder syndrome in adults. … delirium/confusional state; urinary tract infection (symptomatic); atrophic urethritis/vaginitis; use of pharmaceuticals

119. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
     January 01, 2017 - and in 2013 for SGA versus SGA drugs. … in effects associated with individual drugs. … This analysis found that all of the drugs included were superior to placebo. … The newer drugs primarily have evidence only for symptom-based outcomes and adverse events. … • Ensure comparable dosing with the best dosing titration methods for all drugs included.

120. Dietary-Supplements Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
     January 01, 2013 - CER #51: Dietary Supplements in Adults Taking Cardiovascular Drugs Original release date: April … ................................ 5 1 Dietary Supplements in Adults Taking Cardiovascular Drugs … Comparative Effectiveness Review (CER) #51, Dietary Supplements in Adults Taking Cardiovascular Drugs … Dietary Supplements in Adults Taking Cardiovascular Drugs. … OR exp Phytotherapy/ or exp Plant Preparations/ or exp Plant Extracts/ or exp Drugs, Chinese Herbal/