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  1. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
    April 01, 2012 - to determine whether they are potential candidates for the drug. … Food and Drug Administration (FDA); 2010 Apr 9. 39 p. … Food and Drug Administration (FDA); 2010 Apr 27. 35 p. … Available: http://www.vrtx.com/current-projects/drug- candidates/vx-770.html. 23. … /drug-candidates/vx-770.html http://investors.vrtx.com/releasedetail.cfm?
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
    April 01, 2013 - Are drug side effects lessened when two drugs are used at lower dosages instead of one drug at a higher … , patient education, drug surveillance, or interactive drug monitoring) influence results? … , patient education, drug surveillance, or interactive drug monitoring) influence results? … Are drug side effects lessened when two drugs are used at lower dosages instead of one drug at a higher … What is the appropriate timing to evaluate treatment success or failure for each drug/class of drug for
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management-1_research-2007.pdf
    January 01, 2007 - Plans (PDP) and Medicare Advantage Drug Plans (MA-PD). … Role of the clinical pharmacist in improving drug therapy. … Fatal adverse drug events: the paradox of drug treatment. J Intern Med 2001;250(4):327-41. 19. … Adverse drug events in emergency department patients. … for and/or existence of drug-drug, drug- disease, or drug-food interactions or problems) 55.0 5.6
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-high-risk-drugs-rapid-response.pdf
    January 01, 2024 - adjustment, (2) developing a monitoring plan for INR and adverse reactions, (3) documenting and managing drug-drug … (2) developing a monitoring plan for INR and adverse reactions, (3) documenting and managing drug-drug … , and whether the patient is at risk of either an ADE or drug-drug interaction. … Standardized warfarin monitoring decreases adverse drug reactions. … 2) developing a monitoring plan for INR and adverse reactions, (3) documenting and managing drug-drug
  5. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2019.pdf
    January 01, 2019 - Delirium Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting Long-Term Drug … Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review Management of Infertility … Study Comparative Effectiveness of Analgesics to Reduce Acute Pain in the Prehospital Setting Long-Term Drug … Therapy and Drug Discontinuations and Holidays for Osteoporosis Fracture Prevention: A Systematic Review … www.tandfonline.com/doi/full/10.1080/10903127.2019.1657213 https://annals.org/aim/fullarticle/2731605/long-term-drug-therapy-drug-discontinuations-holidays-osteoporosis-fracture-prevention
  6. Dia 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/ijzerman_ahrq-webinar-mcda.pdf
    January 01, 2011 - pressure high blood pressure No adverse events Out-of-Pocket Costs 5 US$ 3 US$ 5 US$ Drug … A Drug B Drug C All MCDA and CA methods decompose a decision problem into a set of criteria … pressure high blood pressure No adverse events Out-of-Pocket Costs 5 US$ 3 US$ 5 US$ Drug … A Drug B Drug C C1 = 0.5 C2 = 0.33 C3 = 0.17 L1.1 = 0.5 L1,2 = 0.25 L1,3 = 0.25 drug A
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
    March 01, 2013 - Psoriatic Arthritis Surveillance Assesment_CER 54_Low CER #54: Drug Therapy for Psoriatic Arthritis … Key Findings: - Key Question 1: Conclusion regarding biologic Disease- Modifying Antirheumatic Drug … This drug is not approved for PsA. … This drug is not approved for PsA. EPC Investigator felt the conclusions were up to date. … Drug Therapy for Psoriatic Arthritis in Adults: Update of a 2007 Report.
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medication-therapy-management_research-protocol.pdf
    January 01, 2014 - Background and Objectives for the Systematic Review The Medicare Prescription Drug, Improvement, … Public Law 108-173)1 established the requirements that Part D plan sponsors must meet with regard to drug … include providing education and counseling, improving medication adherence, and detecting adverse drug … substitution issue; complex regimen that can be simplified with same therapeutic benefit; and potential for drug-drug … : needed drug initiated; unnecessary drug discontinued; change in drug dose, form, or frequency; or
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0264_01-14-2008.pdf
    January 01, 2008 - For children with juvenile idiopathic arthritis, do drug therapies differ in their ability to reduce … For children with juvenile idiopathic arthritis, do drug therapies differ in their ability to Juvenile … For children with juvenile idiopathic arthritis, do drug therapies differ in harms, tolerability, adherence … What are the comparative benefits and harms of drug therapies for juvenile idiopathic arthritis in
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
    February 15, 2017 - Vilazodone: Drug Information. http://www.uptodate.com/contents/vilazodone-drug- information? … Olanzapine: Drug Information. http://www.uptodate.com/contents/olanzapine-drug- information? … Quetiapine: Drug Information. http://www.uptodate.com/contents/quetiapine-drug- information? … Amoxapine: Drug Information. http://www.uptodate.com/contents/amoxapine-drug- information? … Imipramine: Drug Information. http://www.uptodate.com/contents/imipramine-drug- information?
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicare-medication-use_research.pdf
    April 01, 2014 - Drugs are consolidated into 95 drug groups, and drug groups are consolidated into 18 drug categories … and drug group use and catastrophic coverage use. … The effect of Medicare Part D coverage on drug use and cost sharing among seniors without prior drug … Costs for Medicare drug coverage: yearly deductible for drug plans. … categories and groups Drug category Drug group Drug category Drug group Drug category Drug group ADHD
  12. #14 SUBSTANCE ABUSE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/substanceabuse_hi_impact.pdf
    January 01, 2012 - Food and Drug Administration (FDA) in October 2011 about preparing its new drug application and the … National Institute on Drug Abuse (NIDA). Prescription drugs: abuse and addiction. [internet]. … Food and Drug Administration. [internet]. … Food and Drug Administration. [internet]. … [internet]. drug- rehabs.com; [accessed 2011 Jan 5]. [3 p].
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_executive.pdf
    June 01, 2013 - , patient education, drug surveillance, or interactive drug monitoring) influence results? … , patient education, drug surveillance, or interactive drug monitoring) improve safety of the treatments … , patient education, drug surveillance, or interactive drug monitoring) influence results? … care, patient education, drug surveillance, or interactive drug monitoring) improve safety of the … Adverse drug reactions and off-label drug use in paediatric outpatients.
  14. effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
    January 01, 2012 - Therefore, selection of a comparator of the same treatment modality (e.g., drug vs. drug) and same … However, in a CER comparing the effects of drug A versus drug B, misclassification of exposure A would … A lower-dose comparison drug may make the study drug look more effective, 66 Developing an Observational … CER Protocol: A User’s Guide while a higher-dose comparison drug may make the study drug look safer … Pharmacoepidemiol Drug Saf. 2012;21 Suppl 2:81-9. 16. Maldonado G, Greenland S.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-208-bipolar-evidence-summary.pdf
    August 01, 2018 - their lifetime.6 Of all psychiatric conditions, BD is the most likely to co-occur with alcohol or drug … abuse disorders.7 Purpose of Review To assess the effectiveness of drug and nondrug therapies for … Drug treatments have several purposes. … The publications comprised 67 unique drug studies for acute mania, seven drug studies for depression … We found scattered evidence for some drug interventions that were assessed 3 Table A.
  16. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
    January 01, 2012 - The drug is classified by the U.S. … Drug Enforcement Administration (DEA) as a Schedule IV drug, which means DEA will review FDA’s recommendation … This drug combination acts on the central nervous system as an appetite suppressant. … FDA approved the drug on July 17, 2012, on the basis of two completed, phase III trials. … Food and Drug Administration (FDA).
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-therapy-management_executive.pdf
    November 01, 2014 - - drug interactions or adverse event � Drug therapy problems that are resolved as defined by primary … studies but typically including the following: needed drug initiated; unnecessary drug discontinued … Gurwitz JH, Rochon P, Food and Drug Administration. … Out-of-Bounds: Rising Prescription Drug Prices for Seniors. … Association of Chain Drug Stores Foundation.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-prevention_research-protocol.pdf
    November 03, 2011 - Food and Drug Administration (FDA) for migraine prevention in adults come from different drug classes … surveillance, or interactive drug monitoring. … , patient education, drug surveillance, or interactive drug monitoring) influence results? … , patient education, drug surveillance, or interactive drug monitoring) influence results? … Regulating off-label drug use--rethinking the role of the FDA.
  19. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
    January 01, 2012 - Naltrexone/bupropion drug is a combination oral, sustained- release drug intended to fight the body's … A new drug application for treating obesity has not been submitted as of this writing. … This drug combination acts on the central nervous system as an appetite suppressant. … Food and Drug Administration (FDA). … FDA accepts new drug application filing for Qnexa. [internet].
  20. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - -based, online aggregator of prescription drug prices listed prices for the drug at about $27,000 per … Available: http://www.vrtx.com/current-projects/drug- candidates/vx-770.html. … Food and Drug Administration (FDA); 2012 Jan 31 [accessed 2012 Feb 22]. [2 p]. … Drug coverage guidelines. [internet]. … Food and Drug Administration (FDA); [accessed 2012 Jun 28]. [2 p].

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