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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0404_01-14-2011.pdf
    January 01, 2011 - are the long-term (> 90-day) mortality, morbidity, and functional outcomes associated with various drug … Compare two newer drug therapies, both FDA approved, for the treatment of PAH (inhaled treprostinil … Compare combination drug therapies to monotherapy drug treatment Pulmonary Arterial Hypertension … Based on disease etiology and severity of the disease, the timing and optimal combinations of drug therapy … In order to optimize PAH care, newer information regarding the latest drug therapies and combination
  2. effectivehealthcare.ahrq.gov/products/alcohol-misuse-drug-therapy/research-protocol
  3. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
    June 01, 2014 - The drug has been classified by the U.S. … Drug Enforcement Administration as a Schedule IV drug; it became available for prescribing in June … Drug Enforcement Administration (DEA) as a Schedule IV drug (i.e., with a low potential for abuse and … The drug also decreases glucose levels. … Food and Drug Administration (FDA)).
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
    April 01, 2013 - , patient education, drug surveillance, or interactive drug monitoring) influence results? … , patient education, drug surveillance, or interactive drug monitoring) influence results? … care, patient education, drug surveillance, or interactive drug monitoring) influence results? … care, patient education, drug surveillance, or interactive drug monitoring) influence results? … Food and Drug Administration.
  5. effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-2007/research
  6. effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1506.pdf
    December 01, 2015 - Two third- party payers consider Sovaldi a preferred drug; eight consider Harvoni a preferred drug. … Daklinza is an investigational HCV NS5A inhibitor.15 The drug purportedly has a low drug-drug interaction … Gilead gets U.S. approval to sell new hepatitis C drug: drug is seen building on the highly successful … Sovaldi and reigniting debate about drug prices. … Nat Rev Drug Discov. 2013 Jun;12(6):409-11.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
    February 01, 2008 - drug, each newer antiepileptic drug will be compared individually against the older antiepileptic drug … innovator antiepileptic drug group, each generic antiepileptic drug will be compared individually against … the innovator antiepileptic drug (as a separate trial) by dividing the innovator antiepileptic drug … A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product … Condition- specific drug substitution legislation: epilepsy.
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
    August 05, 2010 - that standard dosing as labeled or alternative dosage strategies, such as intermittent dosing and drug … Oral drugs (trade names provided only for drugs under patent) Drug (any trade name): acetaminophen … systemic lupus erythematosus; rheumatoid arthritis; stable angina, chronic; unstable angina Drug … impairment: reduce dose by 50%; elderly patients weighing < 50 kg: initiate at lowest dose Drug … /day Renal impairment and elderly: initiate with lowest dose possible, then monitor closely Drug
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
    April 01, 2012 - concentration-time curve (AUC), maximum drug concentration (Cmax), drug half-life (t1/2), and oral … Clinical cardiovascular effectiveness/efficacy of cardiovascular drug(s) plus supplement versus drug … Intermediate cardiovascular efficacy outcomes of cardiovascular drug(s) plus supplement versus drug … Pharmacokinetic outcomes with cardiovascular drug(s) plus supplement versus drug(s) plus placebo, no … involved in drug metabolism.
  10. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
    December 01, 2013 - Drug Enforcement Administration (DEA) designated lorcaserin as a Schedule IV drug, which removed the … The drug has been classified by DEA as a Schedule IV drug; it became available for prescribing in June … Drug Enforcement Administration (DEA) as a Schedule IV drug (i.e., with a low potential for abuse … It was the first drug approved to treat obesity since 1999.69,71,73 However, FDA referred the drug … FDA approves Qsymia, a weight-loss drug. [internet].
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
    February 01, 2013 - Intervention RLS treatment, including both drug therapies and nondrug therapies. … RLS treatment, including both drug therapies and nondrug therapies. … (Both drug and nondrug treatment options could be considered.) Treatment for RLS. … With RLS Drug: SPM 962 NCT00656110 Neuroma Injections to Treat Restless Legs Syndrome - RCT DrugDrug Interaction Study With Gabapentin Enacarbil and Morphine Drug: morphine; Placebo NCT01516372
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
    November 01, 2023 - Our concluding assessment of this drug remains the same as the prior 2014 review. … We reviewed studies for three medications with Food and Drug Administration approval for alcohol use … As before, we included all medications with Food and Drug Administration indications for alcohol use … https://effectivehealthcare.ahrq.gov/products /alcohol-misuse-drug-therapy/research 2. … Drug and placebo responses in chronic alcoholics. Psychiatric Research Reports. 1968 Mar;24:44-60.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
    April 18, 2013 - We used the WHO drug classification system that does not include tonabersat. … We corrected the drug class for this medication following your recommendations. 3. … We added the tables with the numbers of the enrolled for each drug class. … We found no trials that reported drug effects in gender subgroups. … We requested the FDA review of this drug.
  14. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
    July 01, 2013 - The drug has been classified by the U.S. … Drug Enforcement Administration as a Schedule IV drug; it became available for prescribing in June … Health care delivery infrastructure and patient management: As an oral drug, this drug would not significantly … Drug Enforcement Administration (DEA) as a Schedule IV drug (i.e., with a low potential for abuse … FDA approves Qsymia, a weight-loss drug. [internet].
  15. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - The drug is administered orally, at a dosage of 250 mg, once daily. … Available: http://www.vrtx.com/current-projects/drug- candidates/vx-770.html. 3. … Food and Drug Administration (FDA); 2012 Jan 31 [accessed 2012 Feb 22]. [2 p]. … Aetna non-Medicare prescription drug plan. Subject: cystic fibrosis. [internet]. … Food and Drug Administration (FDA) [accessed 2012 Jun 28]. [2 p].
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
    November 02, 2019 - [mp=title, abstract, heading word, drug trade name, original title, device manufacturer, drug manufacturer … [mp=title, abstract, heading word, drug trade name, original title, device manufacturer, drug manufacturer … [mp=title, abstract, heading word, drug trade name, original title, device manufacturer, drug manufacturer … [mp=title, abstract, heading word, drug trade name, original title, device manufacturer, drug manufacturer … [mp=title, abstract, heading word, drug trade name, original title, device manufacturer, drug manufacturer
  17. effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
    January 28, 2016 - Five third-party payers consider Sovaldi a preferred drug; nine consider Harvoni a preferred drug. … Daklinza purportedly has a low drug-drug interaction profile, which could support its use in patients … Guideline #CG-DRUG-07. [internet]. … Hepatitis virus drug therapy. Drug policy #05.01.50. [internet]. … Specialty drug list. [internet].
  18. S5 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s5.pdf
    October 01, 2007 - Lohr, PhD Background: Interest in new methods for comparative effective- ness, drug and patient safety … structure both interventional and database-oriented studies, particu- larly those concerned with adverse drug … Key Words: comparative effectiveness, drug safety, health care, methods, patient safety, pharmaceuticals … ), trends in evidence-based practice and effective health care, together with Medicare Prescription Drug … L. 108–173), have converged to spotlight issues of drug effec- tiveness and safety.
  19. effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1412.pdf
    December 22, 2014 - In October 2014, a new sofosbuvir drug combination drug was approved (Harvoni; Gilead Sciences) that … It has also been approved as part of a fixed-dose combination with the drug ledipasvir, a drug that … purportedly has a low drug-drug interaction profile, which could support its use in patients with … Gilead gets U.S. approval to sell new hepatitis C drug: drug is seen building on the highly successful … Food and Drug Administration (FDA).
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
    April 01, 2012 - 1 Comparative Effectiveness Review Number 54 Drug Therapy for Psoriatic Arthritis in Adults: Update … Food and Drug Administration (FDA) has approved adalimumab, etanercept, golimumab, and infliximab for … KQ 3: For patients with PsA, do drug therapies differ in harms, tolerability, patient adherence, or … KQ 4: What are the comparative benefits and harms of drug therapies for PsA in subgroups of patients … Drug Therapy for Psoriatic Arthritis in Adults: Update of a 2007 Report.

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