-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0404_01-14-2011.pdf
January 01, 2011 - are the long-term (> 90-day) mortality, morbidity, and functional outcomes
associated with various drug … Compare two newer drug therapies, both FDA approved, for the treatment of
PAH (inhaled treprostinil … Compare combination drug therapies to monotherapy drug treatment
Pulmonary Arterial Hypertension … Based on disease etiology and severity of the disease, the timing and
optimal combinations of drug therapy … In
order to optimize PAH care, newer information regarding the latest drug therapies and combination
-
effectivehealthcare.ahrq.gov/products/alcohol-misuse-drug-therapy/research-protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - The drug has
been classified by the U.S. … Drug Enforcement Administration as a Schedule IV drug; it
became available for prescribing in June … Drug Enforcement Administration (DEA)
as a Schedule IV drug (i.e., with a low potential for abuse and … The drug also decreases glucose levels. … Food and Drug
Administration (FDA)).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
April 01, 2013 - , patient education, drug
surveillance, or interactive drug monitoring) influence
results? … ,
patient education, drug surveillance, or interactive drug
monitoring) influence results? … care, patient
education, drug surveillance, or interactive
drug monitoring) influence results? … care, patient
education, drug surveillance, or interactive
drug monitoring) influence results? … Food and Drug Administration.
-
effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-2007/research
-
effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1506.pdf
December 01, 2015 - Two third-
party payers consider Sovaldi a preferred drug; eight consider Harvoni a preferred drug. … Daklinza is an investigational HCV NS5A inhibitor.15 The drug
purportedly has a low drug-drug interaction … Gilead gets U.S. approval to sell new
hepatitis C drug: drug is seen building on the
highly successful … Sovaldi and reigniting debate
about drug prices. … Nat Rev Drug Discov. 2013 Jun;12(6):409-11.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - drug, each newer antiepileptic drug will be compared individually against the
older antiepileptic drug … innovator antiepileptic drug group, each generic antiepileptic drug
will be compared individually against … the innovator antiepileptic drug (as a separate trial) by
dividing the innovator antiepileptic drug … A theoretical
basis for a biopharmaceutic drug classification: the
correlation of in vitro drug product … Condition-
specific drug substitution legislation: epilepsy.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-pain_research-protocol.pdf
August 05, 2010 - that standard dosing as labeled or alternative dosage
strategies, such as intermittent dosing and drug … Oral drugs (trade names provided only for drugs under patent)
Drug (any trade name): acetaminophen … systemic lupus
erythematosus; rheumatoid
arthritis; stable angina,
chronic; unstable angina
Drug … impairment: reduce dose by
50%; elderly patients weighing < 50
kg: initiate at lowest dose
Drug … /day
Renal impairment and elderly: initiate
with lowest dose possible, then
monitor closely
Drug
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
April 01, 2012 - concentration-time curve (AUC), maximum drug concentration (Cmax),
drug half-life (t1/2), and oral … Clinical cardiovascular
effectiveness/efficacy of cardiovascular drug(s)
plus supplement versus drug … Intermediate cardiovascular
efficacy outcomes of cardiovascular drug(s) plus
supplement versus drug … Pharmacokinetic outcomes with
cardiovascular drug(s) plus supplement versus
drug(s) plus placebo, no … involved
in drug metabolism.
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
December 01, 2013 - Drug Enforcement Administration (DEA) designated lorcaserin as a Schedule IV
drug, which removed the … The drug has
been classified by DEA as a Schedule IV drug; it became available for prescribing in June … Drug
Enforcement Administration (DEA) as a Schedule IV drug (i.e., with a low potential for
abuse … It was the first drug approved to treat obesity since 1999.69,71,73
However, FDA referred the drug … FDA approves Qsymia, a weight-loss
drug. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
February 01, 2013 - Intervention RLS treatment, including both
drug therapies and nondrug
therapies. … RLS treatment, including both drug
therapies and nondrug therapies. … (Both drug and
nondrug treatment options could be
considered.)
Treatment for RLS. … With RLS
Drug: SPM 962
NCT00656110 Neuroma Injections to Treat Restless Legs
Syndrome - RCT
Drug … Drug Interaction Study With
Gabapentin Enacarbil and Morphine
Drug: morphine; Placebo
NCT01516372
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
November 01, 2023 - Our concluding assessment of this drug remains the same
as the prior 2014 review. … We reviewed studies for three medications with Food and Drug
Administration approval for alcohol use … As before, we included all medications with Food and
Drug Administration indications for alcohol use … https://effectivehealthcare.ahrq.gov/products
/alcohol-misuse-drug-therapy/research
2. … Drug and placebo responses in chronic
alcoholics. Psychiatric Research Reports.
1968 Mar;24:44-60.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_disposition-comments.pdf
April 18, 2013 - We used the WHO drug classification
system that does not include tonabersat. … We
corrected the drug class for this medication
following your recommendations.
3. … We added the tables with the numbers of the
enrolled for each drug class. … We found no trials that reported drug effects in
gender subgroups. … We requested the FDA review of
this drug.
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
July 01, 2013 - The drug has
been classified by the U.S. … Drug Enforcement Administration as a Schedule IV drug; it
became available for prescribing in June … Health care delivery infrastructure and patient management: As an oral drug, this drug
would not significantly … Drug
Enforcement Administration (DEA) as a Schedule IV drug (i.e., with a low potential for
abuse … FDA approves Qsymia, a weight-loss
drug. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
June 01, 2013 - The drug is administered orally,
at a dosage of 250 mg, once daily. … Available:
http://www.vrtx.com/current-projects/drug-
candidates/vx-770.html.
3. … Food and Drug Administration (FDA); 2012 Jan 31
[accessed 2012 Feb 22]. [2 p]. … Aetna non-Medicare prescription drug plan. Subject:
cystic fibrosis. [internet]. … Food and Drug Administration (FDA) [accessed
2012 Jun 28]. [2 p].
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-protocol_amended110619.pdf
November 02, 2019 - [mp=title, abstract, heading word, drug trade name, original title, device
manufacturer, drug manufacturer … [mp=title, abstract, heading word, drug
trade name, original title, device manufacturer, drug manufacturer … [mp=title, abstract, heading word, drug trade name, original
title, device manufacturer, drug manufacturer … [mp=title, abstract, heading word, drug trade name,
original title, device manufacturer, drug manufacturer … [mp=title, abstract, heading word, drug trade name, original
title, device manufacturer, drug manufacturer
-
effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
January 28, 2016 - Five third-party payers consider Sovaldi a preferred drug;
nine consider Harvoni a preferred drug. … Daklinza
purportedly has a low drug-drug interaction profile, which could support its use in patients … Guideline
#CG-DRUG-07. [internet]. … Hepatitis virus drug therapy.
Drug policy #05.01.50. [internet]. … Specialty drug list. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/s5.pdf
October 01, 2007 - Lohr, PhD
Background: Interest in new methods for comparative effective-
ness, drug and patient safety … structure both interventional and database-oriented studies, particu-
larly those concerned with adverse drug … Key Words: comparative effectiveness, drug safety, health care,
methods, patient safety, pharmaceuticals … ), trends in evidence-based practice and effective
health care, together with Medicare Prescription Drug … L.
108–173), have converged to spotlight issues of drug effec-
tiveness and safety.
-
effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1412.pdf
December 22, 2014 - In October 2014, a new sofosbuvir drug
combination drug was approved (Harvoni; Gilead Sciences) that … It has also been approved as part of a fixed-dose
combination with the drug ledipasvir, a drug that … purportedly has a low drug-drug interaction profile, which could support its use in patients with … Gilead gets U.S. approval to sell
new hepatitis C drug: drug is seen building on
the highly successful … Food and Drug Administration (FDA).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
April 01, 2012 - 1
Comparative Effectiveness Review
Number 54
Drug Therapy for Psoriatic Arthritis in Adults:
Update … Food and Drug Administration (FDA)
has approved adalimumab, etanercept,
golimumab, and infliximab for … KQ 3: For patients with PsA, do drug therapies differ in
harms, tolerability, patient adherence, or … KQ 4: What are the comparative benefits and harms of
drug therapies for PsA in subgroups of patients … Drug Therapy for Psoriatic
Arthritis in Adults: Update of a 2007 Report.